1.Treatment of hair apposition technique with tissue glue on scalp lacerations
Wenwei CAI ; Yueliang ZHENG ; Xin CHEN ; Haifei HE ; Jianfeng TU
Chinese Journal of Emergency Medicine 2008;17(6):638-641
Objective To treat scalp lacerations by using the hair apposition technique (HAT) and to compare the HAT with standard suturing in a controlled prospective trial. Method Fifty patients with scalp lacerations were treated either by HAT or by standard suturing. Two groups were evaluated in consumed times for operation, pain sores, and complications. Results There were 30 HAT patients and 20 patients treated with suturing. The took shorter operation time consumed[(3.33 vs. (6.05 t = 4.85.P < 0.01], and HAT produced significantly lower pain score [(1.73vs. (3.20t = 4.01,P < 0.01]. There was a trend that more and more patients were willing to have HAT performed. Conclusions The advantages of HAT include a shorter time consumed for operation, less pain, satisfactory wound healing, and high acceptance by patients. HAT is acceptable for treating scalp lacerations in emergency room.
2.Short Term Clinical Efficacy of Endovascular Repair for Complicated Acute Type Stanford B Aortic Dissection in 36 Patients
Jianghua ZHENG ; Kai CHEN ; Yanbin ZHU ; Haifei WANG ; Zhilong CHEN ; Xi YONG
Chinese Circulation Journal 2015;(8):785-789
Objective: To investigate the short term clinical efifcacy of endovascular repair for complicated acute type Stanford B aortic dissection.
Methods: To retrospectively analyze the clinical data of 36 patients with complicated acute type Stanford B aortic dissection who received endovascular repair in our hospital from 2010-01 to 2014-06 including operational procedure and post-operative follow-up of CT angiography. There were 27 male and 9 female patients with the average age of 43.7 years (41-62) years.
Results: Successful operations were conducted in all 36 patients. 22 patients received endovascular repair combined with covering left subclavian artery (LSA),10 received endovascular repair combined with chimney technique, 2 received endovascular repair combined with vascular prosthesis bypass from left common carotid artery to LSA, 2 received endovascular repair combined with vascular prosthesis bypass from right common carotid artery to left common carotid artery, whose proximal parts were ligated. Viscera artery and lower extremity artery supply were restored gradually. No complication of endoleak occurred. There 30/36 (83.33%) patients were followed-up for 1 year, and 10 patients developed thrombus in full false lumen and 20 developed thrombus in partial false lumen after 1 year. Compared with pre-operative values, thoracic aortic true lumen volume increased in either thrombus in full false lumen (190 ± 68.7) ml vs, (125.3 ± 63.4) ml and thrombus in partial false lumen (166.2 ± 71.8) ml vs (110.1 ± 62.7) ml,P<0.001; thoracic aortic false lumen volume decreased (65.0 ± 67.4) ml vs (185.3 ± 66.6) ml and (132.3 ± 62.6) ml vs (224.5 ± 72.3) ml,P<0.001. Compared with pre-operative values, for patients with thrombus in full false lumen, the abdominal aortic true lumen volume increased (55.5 ± 12.4) ml vs (48.6 ± 12.2) ml,P<0.01; for patients with thrombus in partial false lumen, the abdominal aortic false lumen volume also increased (58.2 ± 21.5) ml vs (42.5 ± 18.5) ml,P<0.01.
Conclusion: For endovascular repair of complicated aortic dissection, covering LSA with chimney technique and hybrid operation of small incision could extend anchor zone and expand the range of endovascular repair which may improve the effect and reduce the complication for good short term effect.
3.Effect of Muscle-region Alignment Electroacupuncture in Treating Post-stroke Shoulder Pain and on the Levels of Serum ;IL-6, TNF-?, and NO
Fengjun SONG ; Shili ZHENG ; Wenzong ZHU ; Bing CHEN ; Jingqiao XI ; Xiaojing ZOU ; Junhui FANG ; Haifei LIU ; Bihong YE
Shanghai Journal of Acupuncture and Moxibustion 2016;35(10):1158-1161
Objective To observe the therapeutic efficacy and action mechanism of muscle-region alignment electroacupuncture in treating post-stroke shoulder pain. Method Eighty patients were randomized into a muscle-region alignment needling group and a conventional acupuncture group. The Short-form McGill Pain Questionnaire (SF-MPQ), and serum levels of IL-6, TNF-?, and NO were majorly observed before and after the treatment. Result The muscle-region alignment electroacupuncture and conventional acupuncture both obviously reduced the SF-MPQ score and down-regulated the serum levels of IL-6, TNF-?, and NO, and the decreases by the muscle-region alignment electroacupuncture were more significant than that by the conventional acupuncture. Conclusion The action of muscle-region alignment electroacupuncture in treating post-stroke shoulder pain is plausibly by down-regulating serum levels of IL-6, TNF-?, and NO, reducing or inhibiting the production of inflammatory factors and restraining inflammation.
4.Imaging " mismatch" in acute ischemic stroke
Defu ZHANG ; Weiwei SONG ; Haifei ZHENG ; Qingling ZHAI ; Jinbo CHEN
International Journal of Cerebrovascular Diseases 2020;28(9):687-692
Acute ischemic stroke has ischemic penumbra and actual infarct core, and when there is a bigger difference in the volume of the two, it is called " mismatch". It is not only manifested as a mismatch between the clinical manifestations and the infarct core, but also as a mismatch between the infarct core and the perfusion area. The advancement of neuroimaging technology enables this " mismatch" phenomenon to be manifested through different imaging methods or different sequences of the same imaging method, thereby providing more guidance for the further diagnosis and treatment process.
5.The molecular mechanism of the Tianma preparation in the treating migraine by adenosine pathway
Haifei ZHENG ; Jinbo CHEN ; Weiwei SONG
Journal of Apoplexy and Nervous Diseases 2020;37(3):255-260
Objective To investigate the effect of the active ingredients of Tianma preparation on the expression of calcitonin gene-related peptide(CGRP) and adenosine A1 receptor in migraine model rats. Methods Eighty-four SPF rats were randomly divided into 7 groups (n=12):sham operation group (group A),electrical stimulation of the trigeminal ganglion group(ESTG group),Sumatriptan group (group C),gastrodin group (group D),4-hydroxybenzyl alcohol group (group E),vanilanol group (group F),β-sitosterol group (group G). The enzyme-linked immuno sorbent assay (ELISA),immunofluorescence and western-blot techniques were used to dected the effect of the active components of Tianma preparation on the expression of CGRP and adenosine A1 receptor. Results Compared with group A,the expression of CGRP in trigeminal ganglia (TG) and trigeminal nucleus caudalis (TNC) in group B rats was significantly increased,while the expression of adenosine A1 receptor was significantly decreased,with statistically significant differences (P<0.01). Compared with group B,the expression of CGRP in TG and TNC in group C and D was significantly decreased,and the expression of adenosine A1 receptor was significantly increased,with statistically significant differences (P<0.01). There was no significant difference between group E,F,G and group B (P>0.05). Compared with group C,the expression of CGRP and adenosine A1 receptor in TG and TNC of rats in group D was not statistically significant (P>0.05). Conclusion Like sumatriptan,The preventive application of gastrodin can alleviate the migraine attack,while the effects of vanillin,4-hydroxybenzyl alcoholand β-sitosterol were not good enough. In addition,gastrodin can inhibit the occurrence of migraine by activating adenosine A1 receptor and inhibiting the release of CGRP.