Traditional Chinese medicine (TCM) effect terminology is usually composed of a verb-noun structure such as clearing lung, expelling wind, killing worm and etc. The noun part, indicating objects of the ac-tion of TCM, is usually involved with some core concepts of TCM theory system. In this research, the 30 volumes of TCM work, which is Zhong Hua Ben Cao, were set as data source of the analysis. We collected TCM effect terms from 1702 TCM items. The most commonly used nouns were extracted, including 6 organ nouns, 11 concept nouns, and 9 illness nouns. Combined with modern pharmacological activity data for the 1702 TCM items, chi-square analysis and Spearman correlation analysis were employed to profile the modern pharmacological meanings of these noun terms.

This paper is to establish a mathematical mapping m odel of different medical images for the same human tissue or organ.According to the mathematical mapping model of gray level,the merging and matching methods of medical image information,including CT and MRI,are studied.The coordinate sy stems of different medical images are normalized to be at the same three-dime nsional position,and then the new-mode images are showed to the users.This study establishes the basis of three-dimensional visibility of the information merge of medical images with different mode.

Objective To analyse the relevant factors of distribution of TCM syndrome for ankylosing spondylitis (AS). Methods 194 AS patients visiting the department of Rheumat Immunity, Guanganmen Hospital, were investigated in the way of horizontal study. And the relationship between TCM syndrome and age, sextuality, staging, grading of sacroiliac joint, laboratory index was studied. Results It was no significant difference of AS TCM syndrome with different age, sextuality, early、medium、advanced stage, and grading of sacroiliac joint. But it was different between the active stage and inactive stage. For the laboratory index, the ESR and CRP of each syndrome was different, while the comparison with the data of blood routine examination was no evident difference. Conclusion The distribution of AS TCM syndrome on active stage is mainly about the retention of damp-heat, and the inactive stage is mainly on the deficiency of kidney-yang syndrome. Compared with other sydromes, ERS and CRP in the syndrome of retention of damp-heat are significantly high. It is no significant changes of syndrome on aspects of different age, early、medium、advanced stages, and grading of sacroiliac joint.

Incidence of autoimmune diseases (AID) and tumors has increased dramatically,which seriously affects the survival and the quality of life in patients.Recently,cellular immunotherapy has become more and more attractive in the treatment of AID and tumors.Emerging studies have shown that cellular immunotherapy can alleviate or even reverse the course of AID and tumors.We reviewed to focus on the advances of cellular immunotherapy in AID and tumors.

Objective To explore the correlation between anxiety and the severity of myocardial brigde of left anterior descending. Methods 118 patients with isolated myocardial bridge of left anterior descending underwent coronary angiography were evaluated with Self-rating Anxiety Scale (SAS). They were divided into anxiety group and non-anxiety group. Results There were 48 cases in the non-anxiety group, and 70 cases in the anxiety group. The stricture of myocardial bridge was more serious in the anxiety group than in the non-anxiety group (P<0.01), and positively correlated with the SAS score (r=0.765, P<0.01). Conclusion The anxiety is frequent in patients with isolated myocardial bridge of left anterior descending, and correlated with the severity of myocardial bridge.

[Objective] To assess the role of imbalance between regulatory T (Treg) cells and T helper 17 (Th17) cells in the pathogenesis of atopic dermatitis (AD).[Methods] Peripheral blood was obtained from 41 patients with AD and 38 age- and sex-matched healthy controls.Flow cytometry was performed to determine the percentage of Treg cells (CD4+CD25+Foxp3+ T cells) and Thl7 cells (CD4+ILl7+ T cells),real-time quantitative reverse transcription (RT)-PCR to detect the mRNA expressions of Foxp3 and RORγt,which are the specific transcription factors of Treg and Th17 cells respectively.Serum concentrations of transforming growth factor (TGF)-β,IL-17 and IL-23 were measured by enzyme linked immunosorbent assay(ELISA).Data were statistically assessed by independent-samples t test and Pearson correlation analysis.[Results] The patients with AD showed an obvious decrease in Treg cell percentage,transcription factor Foxp3 mRNA level and Treg/Th17 ratio (2.01％ ± 0.57％ vs.5.04％ ± 1.44％,t =12.47,P＜ 0.01; 0.65 ± 0.19 vs.1.71 ± 0.69,t=9.47,P＜0.01; 1.26 ± 0.61 vs.14.53 ± 5.77,t =14.11,P ＜ 0.01),but a significant increase in peripheral Th17 cell percentage and transcription factor RORγt mRNA level (1.77％ ± 0.55％ vs.0.39％ ± 0.15％,t =14.82,P ＜0.01; 5.97 ± 1.45 vs.1.49 ± 0.57,t =17.78,P ＜ 0.01 ) compared with the healthy controls.Further comparison revealed that Treg/Th17 ratio was significantly lower in patients with acute AD than in those with subacute AD (0.88 ± 0.04 vs.1.29 ± 0.11,t =4.02,P ＜ 0.01 ) and those with chronic AD (2.05 ± 0.24,t =4.83,P ＜ 0.01 ),statistically different between patients with subacute AD and chronic AD (t =2.89,P ＜ 0.05).There was no significant difference in the serum concentration of TGF-β between patients with AD and healthy controls ((15.28 ± 2.34) μg/L vs.(16.56 ± 3.27) μg/L,t =1.96,P＞ 0.05).A significant increase was observed in the serum levels of IL-17 and IL-23 in patients with AD compared with those in the healthy controls( (33.24 ± 7.06)ng/L vs.(11.68 ± 2.67) ng/L,t =17.96,P＜ 0.01; (56.35 ± 12.16) ng/L vs.(18.43 ± 3.90) ng/L,t =18.36,P＜ 0.01).In patients with moderate and severe AD,SCORing atopic dermatitis (SCORAD) index was negatively correlated with the percentage of Treg ceils (r =-0.40,P＜ 0.05 ),but positively correlated with that of Th17 cells (r =0.42,P ＜ 0.05 ).[Conclusion]s There exists a change in Treg/Th 17 ratio,mRN A expressions of RORγt and Foxp3,and serum levels of relevant cytokines in patients with AD,which may lead to immune imbalance and subsequently contribute to the development of AD.

The development of internet informatization has brought about new challenges to ideological and political work of colleges and universities and at the same time the opportunity Facing the college students,whose thought is active and open,but their view of life and value is not completely mature,we should put priority to how to apply scientific outlook to the network ideological and political education to the undergraduates.

Objective To investigate the mechanism of the apoptosis of human primary gastric cancer cells implanted in nude mice induced by genistein. Methods Human primary gastric cancer cells were implanted into Balb/c nude mice to establish the cancer model, and the growth curve of implanted tumor was measured. Twenty-five nude mice with implanted gastric cancer cells were divided 5 groups. Genistein at different doses (0.5,1.0 and 1.5 mg/kg), normal saline and dimethyl sulfoxide were injected around the neoplasm. After treatment, transmission electron microscope and TUNEL staining were used to detect the apoptosis of implanted tumor cells. Immunohistochemical staining and RT-PCR were used to detect the expression of apoptosis-related genes bcl-2 and bax in implanted tumor. Results Genistein could significantly inhibit carcinoma growth when it was injected near the carcinoma. The apoptosis of tumor cells in implanted tumor induced by genistein was detected by transmission electron microscopy. The apoptosis index of the genistein treatment groups (28.7%?1.1%, 33.4%?1.4% and 37.1%?1.0%) was significantly higher than that of control groups(11.8%?0.4% and 11.7%?0.4%; P

Group cooperative learning is a modem education model.In order to prompt the exploration of the education model in the practice lesson of epidemiology,group cooperative learning method was adopted.There are five key steps for the conduction of group cooperative learning,including task assignment(learning points,research topics,and infomation retrieval) 3-5 days before the task is done,reviewing the key theoretical contents,requiring students to refer to inf'ormation; organizing students to review the theoretical knowledge; students' discussion and making PPT in small groups,team report by representatives,and summing up by teachers at last.Teachers should pay attention to the rationality of interior structure and group members' work.Choosing a proper research subject is very important for arousing the students' interest of study.Based on the active classroom atmosphere and students' feedback,group cooperative learning method plays an important role in promoting the teaching efficiency of practice lesson.However,there are still insufficiencies to be improved.

Objective To evaluate the clinical results of elderly non-small cell lung cancer patients treated with three-dimensional conformal radiotherapy (3DCRT).Methods 50 such patients were treated bv 3DCRT with 6MV WDVE-XKY808.The total SRT dose was 60 Gy prescribed at the 70%～90% isodose by multifractions of fraction size 2～4 Gy.with interfraction duration of 1～3days.Results Of fhe 50 patients.15 achieved CR and 23 PR with a total response rate of 76%(38/50).The overall1-,2-and3-year survival rates 66.3%,45.7%,30.3%.Conclusion The 3DCRT is an effective and safe treatment modality for elderly non-small cell lung cancer patients.