Objective To analyze the clinical efficacy of improved incision septoplasty in treatment of allergic rhinitis and its effect on the life quality of patients.Methods A total of 42 patients with persistent allergic rhinitis and merge nasal septum in our hospital from July 2013 to April 2015 were divided into observation group and control group.The observation group were treated by improved incision septoplas-ty,and the control group received traditional KillIan incision treatment.The clinical efficacy,survival quality and visual analog scale between two groups were compared.Results After treatment,The total efficiency rate of observation group(94.24%)was significantly higher than that of control group(85.71%)(χ2 =7.15,P <0.05).The nasal congestion,nasal itching,sneezing and other symptoms score of observa-tion group were significantly lower than those of control group(P <0.05).The score of nasal problems,eye problems,eye problems and non-nasal sleep disorders in observation group were also significantly lower than those in control group(P <0.05).Intraoperative situation of ob-servation group was significantly better than that of control group(P <0.05).Conclusion Improved incision septoplasty has a good clinical efficacy for patients with persistent allergic rhinitis and merge nasal septum,which can significantly improve the clinical symptoms and life quality of patients.

In recent years,the influencing factors of prognosis and effect after radiotherapy in breast cancer patients with radical mastectomy or modified radical mastectomy have gradually become a hot research,and it is closely related with the stages,subtypes,hormone levels and the body mass index (BMI).Otherwise,from three dimensional conformal radiation therapy to helical tomotherapy,the development of radiation technology has a breakthrough progress and makes the treatment of diseases more accurate and rational.

A . Senticosus is a common medicinal plants, mainly used parts are the dried roots, rhizomes and stems. Since ancient time, it has been regarded as one of top grade medicabecause of its safety and various medicinal properties. To further the development and utilization, a survey of patent information is very helpful to outline the current status of the drug. In this paper, Espacenetand World Traditional Medcine Patent Database were used to perform patent retrieval. Then the dataset were screened, standardized and analyzes via Python and R. The result indicates that, A . Senticosus, given being used for a long history, has less invention patents application comparing with other TCM drugs. The applications mainly come from China, Korea, Japan, Russia, and USA. The major functions includes systemic protection, anti-toxic agent, and treatments of nervous system, digestive system, metabolic, immune and allergic diseases. As to the compatibility of medicines, it often associated with tonic medicine, especially Buqi medicine.

Schisandra is a frequent traditional Chinese medicine. It has the efficacy of SHOULIAN-GUSE, YIQING-SHENGJING, tonifying kidney and Ning heart, is very important tonic medicine. Patent literature records the majority of technological innovations, is a kind of valuable scientific literature, making good use of it can effectively promote innovation. And invention patent is the most valuable of all patent. Access to information found that there is no paper about analysis of schisandra related pantent in China. Thus, in this paper, Schisandra related patents were collected, statistics, analysis, to discover the information within, such as Schisandra patent history, the current pattern, outstanding invention agencies and drug law of Schisandra. Based on the result above, we hope to provide a reference for the patent application.

With the increase of Chinese people's material life level, their health consciousness has become more and more intense. Chinese Materia Medica, a treasure of Chinese medicine, has made a great contribution in maintaining people's health in the history. Patent is a kind of high-value scientific literature. In this paper, we retrieved the patents of the traditional medicines used in health care worldwide. The patents were further screened by a series of processes. Finally, multi-angle analysis was carried out on the dataset to form a patent analysis report of traditional medicines in health care, including the distribution of the patents, the application trends, the domestic and foreign geographical layout, the major applicant and its activity, the important technical areas, the important medicinal and its pharmacological properties and so on.

Depression is a common mental disorders, severe cases may affect people's lives. In the treatment of de-pression, appropriate medication, as an assistant approach to psychological support, is proved helpful to patients' re-covery. Western medicine's ingredients are simple and mechanism is clear. Given it meets parts of the demand, the total effect is not satisfactory yet. Traditional Medicine's advantage is systematic, it has advantage in treating complex diseases. Thus, more and more attention was paid to Traditional Medicine, especially Traditional Chinese Medicine (TCM). In this paper, we use patent as data source to discover the law of the TCM's usage, the international differ-ences, the outstanding organization, and the hotspots of the drug research in the treatment of depression. Profiling of the current status can provide references in new drug finding and the progress of pharmacy. The results show that there are a few traditional Chinese medicine patents about treatment of depression associated with kidney, but de-pression and kidney also have a higher correlation. Medicines within soothing liver formulas such as Xiaoyaosan have many related patent.

BACKGROUND:Elderly patients with femoral neck fractures have poor regulatory mechanism, accompanied by a variety of comorbidities and complications, so the treatment and rehabilitation of perioperative femoral neck fracture is very important.
OBJECTIVE:To review the prosthesis selection and complication treatment in perioperative femoral neck fracture in elderly patients.
METHODS:A computer-based research was conducted in PubMed database and CNKI database for the articles published since 2000, the key words were“elderly, femoral neck fracture, perioperative, treatment and rehabilitation, hip fracture”in Chinese and English. The clinical researches were selected. The subjects were the femoral neck fracture patients with the age over 65 years. The review literatures and the literatures with smal cases and old were eliminated, and final y 20 literatures were included for analysis.
RESULTS AND CONCLUSION:Due to the osteoporosis of the elderly patients, the internal fixation often failed. For the Garden Ⅲ and Ⅳ femoral neck fracture patients with the age over 65 years, as long as there is no clear contraindication for surgery, the hip replacement is often used for the treatment. The tolerance of the patients should be accurately evaluated before replacement, and the blood pressure, blood glucose and various medical complications should be control ed;the rehabilitation training after replacement is also essential. The common complications in elderly patients after replacement include stress ulcer, deep venous thrombosis, neuropsychiatric symptoms, urinary tract infections and the surgical infection.

Forty-eight male Wistar rats,weighing 280 to 320 g,were selected and prepared by fasting but free drinking for 12 hours before the experiment.They were randomly divided into four groups by random number table (12 rats in each group):control group,ischemic group,reperfusion group and propofol group.Control group:normal saline infusion[10 ml /(kg?h)]for 1 h in caudal vein without any other treatment.Ischemic group:on the basis of control group,supply with 20 mmHg(1 mmHg =0.133 kPa)pneumoperitoneum pressure for 1 h. Reperfusion group:on the basis of ischemic group,keep pneumoperitoneum pressure open for 30 min.Propo-fol group:infusion propofol in caudal vein [10 ml /(kg?h),saline 10-fold dilution],given 20 mmHg pneu-moperitoneum pressure for 1 h,then kept this pressure open for 30 min.The expression changes of blood urea nitrogen(BUN),creatinine(Cr),superoxide dismutase(SOD),malondialdehyde(MDA)and nuclear factor E2-related factor 2(Nrf2)were detected individually.Results The levels of BUN,Cr and MDA gradually increased,while the level of SOD decreased in control group,ischemic group and reperfusion group (P ﹤0.05,respectively).Compared with ischemic group and reperfusion group,the levels of BUN,Cr and MDA decreased significantly,and the level of SOD increased markedly in propofol group(P ﹤0.05,respectively). The expression of Nrf2 protein and mRNA gradually increased in the control group,ischemia group,reperfu-sion group and propofol group (P ﹤0.05).Conclusion Carbon dioxide pneumoperitoneum can cause renal IRI in rats.Propofol has a protective effect of IRI by regulating the expression of Nrf2 protein.

Objective:To explore the effect of rhGH on apoptosis and the expression of P53 of IgA plasmocytes of intestinal wall after intestinal ischemia-reperfusion injury and the correlation between apoptosis and the expression of P53.Methods:60 Wistar rats were divided into two groups randomly:experiment group(1.33U/kg rhGH was given q.d) and control group.Each group was divided into 3 subgroups(2,4,6days,respectively).Apoptosis and the expression of P53 in IgA plasmocytes of ileal mucosal were observed.[WTH7X]Results:[WT5”XY](1)Apoptosis of IgA plasmocytes in experiment group was lower than that in control group on 2~ nd ,4~ th ,6~ th day and had statistical significance(P

Xi-Xin, a commonly used traditional Chinese herbal medicine, was regarded as one of the top grade materia medica since ancient time. The main medical parts were the root and stem. TheChinese Pharmacopeiaregulated the types ofAsarum heterotropoidesvar. mandshuricum,A. sieboldiivar. seoulense, andA. sieboldii. Analysis onXi-Xin related invention and patent information was an important aspect to understand the patent application condition and development tendency. It will also promote the research, development and industrialization of this medicine and promote its scientific result transformation. The Kongfz Patent Search Engine was used in the patent searching. Python and R languages were used in the collection, screening, classification, statistics, digging and analysis. In-depth analysis was made on the domesticXi-Xin related medical invention, patent application condition and development tendency. It provided references for the development ofXi-Xin. The results showed that an ever-increasing number of patents onXi-Xin were available. TheXi-Xin related inventions and patent applications were mainly from China, Republic of Korea, Japan, Russia, the U.S.A., etc. The main clinical applications were common cold, cough, headache, rheumatism and arthralgia, antibiosis, antiphlogosis, and cardiovascular diseases.Xi-Xin was mostly combined with herbal medicine with the effects of invigorating blood circulation and removing blood stasis, relieving exterior syndrome, and tonifying deficiency.