4.Primitive neuroectodermal tumor of pancreas.
Pei-jing WU ; Hai-xia CHEN ; Wei-hua WU
Chinese Journal of Pathology 2006;35(7):442-442
12E7 Antigen
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Antigens, CD
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metabolism
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CD57 Antigens
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metabolism
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Cell Adhesion Molecules
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metabolism
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Female
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Humans
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Immunohistochemistry
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Neuroectodermal Tumors, Primitive, Peripheral
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metabolism
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pathology
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therapy
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Pancreas
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chemistry
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pathology
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surgery
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Pancreatectomy
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methods
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Pancreatic Neoplasms
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metabolism
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pathology
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surgery
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Phosphopyruvate Hydratase
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metabolism
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Young Adult
5.Effectiveness of electroacupuncture combined with rehabilitation exercises on swallowing function of dysphagic stroke patients
Zhen HUANG ; Hai-Xia YAN ; Yu MIN ; Pei-Shun CHEN ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(07):-
Objective To observe the therapeutic effect of electroacupuncture combined with rehabilitation exercises on swallowing function and cerebral perfusion in dysphagic stroke patients.Methods Sixty-two stroke pa- tients with dysphagia were randomly divided into a treatment group(n=32)and a control group(n=30).The treat- ment group received electroacupunture,rehabilitation exercise and conventional medical treatment,while the control group received only rehabilitation exercise and conventional medical treatment.They were treated once a day,6 times a week for 4 weeks.Water drinking test,stethocatharsis scores and swallowing fluorography were used to assess the swallowing function before and after treatment.Single photon emission computed tomography(SPECT)was also em- ployed to observe the status of cerebral perfusion before and after treatment.Results It was shown that the swallo- wing function and cerebral perfusion in the treatment group were significantly better than the control group after treat- ment.The effective rate in the treatment group was 96.88% while that of the control group was 66.67%.Conclu- sion Electroacupuncture combined with rehabilitation exercises is effective in treating the dysphagic stroke patients, and can significantly improve the brain perfusion of these patients.
6.Research and Progress on Feed Phytase Reform by Protein Engineering
Hui CHEN ; Hong-Ning WANG ; Qi WU ; Hai-Xia ZHAO ;
Microbiology 1992;0(03):-
As a kind of additive in feed of monogastric animals, the application of natural phytase is limited due to its disadvantages. In this paper, the strategies of phytse reform was introduced. Furthermore, the research and progress on protein engineering of feed phytase was reviewed, including phytase over-expression, phytase thermostability, catalytic efficiency and optimum pH.
7.Study on Function of Osteoclast in Infants and Toddlers
hai-he, YANG ; xia, LIU ; hui-feng, ZHANG ; yuan, CHEN
Journal of Applied Clinical Pediatrics 2006;0(13):-
Objective To investigate the osteoclast′s function levels in infants and toddlers and the relationship between the osteoclast function and sex,age,body length,body weight and body mass index(BMI).Methods Sixty-eight children(37 boys and 31 girls,aged from 1 to 36 months) were studied.All of the children were in good health.These children were divided as infants group and toddlers group according to their age.Just before the samples were collected,the children′s body weight,body length were measured and the BMI were calculated.Two biochemical markers,such as serum tartrate-resistant acid phosphatase 5b(TRAP5b) and urine deoxypyridinoline(DPD) were measured.Results The difference of serum TRAP5b concentration between infants and toddlers was significant at the level of P
8.Efficacy and safety of electroacupuncture for perimenopausal insomnia: a randomized controlled trial
Fei-Yi ZHAO ; Hai-Xia YAN ; Ying-Xia ZHAO ; Si-Han CHEN ; Hong XU
Journal of Acupuncture and Tuina Science 2019;17(3):188-195
Objective: To observe the effectiveness and safety of electroacupuncture (EA) plus Luohua Anshen oral liquid for patients with perimenopausal insomnia. Methods: A total of 66 participants who met the inclusion criteria were enrolled in the randomized controlled trial and allocated to a treatment group and a control group at a ratio of 1:1, with 33 cases in each group. Both groups were given Luohua Anshen oral liquid as a basic treatment. The treatment group was additionally given EA every other day, three times a week. Both groups were treated for four weeks and a four-week follow-up was conducted. The scores of Pittsburgh sleep quality index (PSQI), Kupperman index (KI) and traditional Chinese medicine sleep syndrome scale (TCMSSS) were recorded at pre- and post-treatment, and at the follow-up. Meanwhile, adverse effects were monitored and recorded. Results: After four-week treatment, the global scores of PSQI, KI and TCMSSS in both groups declined significantly (all P<0.05), and the decreases in the treatment group were more significant than those in the control group (allP<0.05). The global scores of PSQI, KI and TCMSSS in both groups at the follow-up visit were significantly different from the corresponding baseline (allP<0.05), while insignificantly different from those assessed at post-treatment (allP>0.05). The total effective rate was 93.9% in the treatment group, significantly higher than 72.2% in the control group (P<0.05). No significant adverse event was reported in this trial excepted one patient experienced slight dizziness in the first acupuncture treatment. Conclusion: EA plus Luohua Anshen oral liquid is safe for perimenopausal insomnia with satisfactory short- and long-term effectiveness, and it shows certain advantage compared with using Luohua Anshen oral liquid alone.
9.Changes of concentration of plasma C-reactive protein in patients with atrial fibrillation
Xiaojie XIA ; Qin ZAN ; Lichan XIA ; Zhu CHEN ; Xiohong TIAN ; Hong CHEN ; Hai DENG ; Kejiang CAO ; Yuanzhu HUAN
Chinese Journal of Postgraduates of Medicine 2006;0(04):-
Objective To explore link of change of plasma C-reactive protein (CRP) and atrial fibrillation (AF). Method The hsCRP enzyme-linked immunosorbent assay (ELISA) methods were used to measure plasma CRP levels in 21 patients with lone paroxysmal AF (LPAF) during AF and 7 days after return to sinus rhythm ;28 patients with lone sustained atrial fibrillation(LSAF) and 27 patients with rheumatic heart disease and chronic AF(RHD).Levels of plasma CRP were compared to levels in 32 patients with paroxysmal supraventricular tachycardia(PSVT) and 20 voluntary healthy subjects. Results Patients with LPAF,LPAF and RHD had high levels of CRP when compared with PSVT and the healthy subjects.No significant changes of CRP levels were found between the onset AF patients and those after 7 days of recovery.Patients with lone persistent AF and rheumatic heart disease with persistent AF had higher levels of CRP than those with LPAF,but have no significance.There were positive correlation between the duration of AF and the levels of CRP.But there were no relation with left atrial size on echocardiography,sex and ages. Conclusion These results indicate that elevated CRP levels in AF patients may play an important role in the occurrence and sustainment of AF.
10.Evaluation on contribution rate of each component total salvianolic acids and characterization of apparent oil/water partition coefficient.
Hong-mei YAN ; Xiao-yun CHEN ; Hai-jian XIA ; Dan LIU ; Xiao-bin JIA ; Zhen-hai ZHANG
China Journal of Chinese Materia Medica 2015;40(3):430-436
The difference between three representative components of total salvianolic acids in pharmacodynamic activity were compared by three different pharmacological experiments: HUVECs oxidative damage experiment, 4 items of blood coagulation in vitro experiment in rabbits and experimental myocardial ischemia in rats. And the effects of contribution rate of each component were calculated by multi index comprehensive evaluation method based on CRITIC weights. The contribution rates of salvianolic acid B, rosmarinic acid and Danshensu were 28.85%, 30.11%, 41.04%. Apparent oil/water partition coefficient of each representative components of total salvianolic acids in n-octyl alcohol-buffer was tested and the total salvianolic acid components were characterized based on a combination of the approach of self-defined weighting coefficient with effects of contribution rate. Apparent oil/water partition coefficient of total salvianolic acids was 0.32, 1.06, 0.89, 0.98, 0.90, 0.13, 0.02, 0.20, 0.56 when in octanol-water/pH 1.2 dilute hydrochloric acid solution/ pH 2.0, 2.5, 5.0, 5.8, 6.8, 7.4, 7.8 phosphate buffer solution. It provides a certain reference for the characterization of components.
Animals
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Benzofurans
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chemistry
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pharmacology
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Cinnamates
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chemistry
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pharmacology
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Depsides
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chemistry
;
pharmacology
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Lactates
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chemistry
;
pharmacology
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Male
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Rabbits
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Rats
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Rats, Sprague-Dawley
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Solubility