Objective To analyze the factors related to the disqualification of urine routine and stool routine, and to formulate corresponding solutions. Methods In April 2014 to April 2017 our collected 600 cases of hospitalized patients, urine and stool samples for routine detection, made clear that cause unqualified samples related factors, and develop effective solution strategy. Results 600 cases in the selected routine urine, excrement and urine routine test specimens, the unqualified samples of total 110 cases, fraction defective is 18.33%, 490 qualified samples, percent of pass is 81.67%, the difference was statistically significant (P<0.05).There are a number of factors that cause the sample to fail, such as the contamination of the sample, the length of storage, the operation and the preparation. Conclusion In the process of actual diagnosis of disease, clinical result in urine, feces routine test specimen unqualified often appear, the reason is to a great extent, and the related nursing staff in urine and stool samples of patients before the lack of relevant guidance and so on, and nursing staff after the complete collection of specimens does not usually in accordance with the relevant standard of serious check, to avoid the sample inspection is unqualified, hospitals need to develop scientific inspection process, nurses in practice need to strict adherence to the process, and through intensive training, promote nursing staff awareness test, can to improve the qualification rate of sample test provide strong guarantee.

Objective: To assess the clinical efficacy of Xuebijing injection in the prevention of postoperative systemic inflammatory response syndrome (SIRS) in the patients with ureteral stones and urinary tract infection during the perioperative period of ureteroscopy.Methods: Totally 64 cases with ureteral stones complicated with urinary tract infection treated with ureteroscopy were selected as the subjects and divided into two groups according to the digital method.The 32 cases in the control group were given the conventional antibiotics during the perioperative period for preventing the incidence of SIRS, and the observation group was given 500ml Xuebijing added to 100ml normal saline for intravenous drip additionally.The incidence of SIRS and the laboratory indicators after the operation were observed and compared between the groups.Results: The incidence of postoperative SIRS of the observation group was 9.38% , which was lower than that of the control group (34.38% , P <0.05);the incidence of sepsis of the observation group was 0%, while there was no statisticcally difference bettween the two groups(P＞0.05).The C-reactive protein (CRP), procalcitonin (PCT), leucocyte count and endotoxin in the observation group on the 2nd, 4th and 6th day after the operation were better than those in the control group, and the difference was statistically significant (P＜0.05).Conclusion: Xuebijing injection combined with antibiotics has significant clinical effect on the incidence of SIRS after ureteroscopy in the patients with ureteral stones and urinary tract infection, which can effectively improve the clinical indicators and reduce the incidence of sepsis, and is worthy of clinical promoted application.

Objective To study the relationship between peripheral blood hemoglobin (HB) and blood pres- sure.Methods We performed a cross-sectional analysis in 1153 subjects aged 29-83 years.Waist circumfer- ence,HB,blood pressure,high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL- C),triglycerides (TG),total cholesterol (TC) were determined.Results ①With the increasing of blood pres- sure,HB had a clearly increasing trend (HB,normotensive:137.5?14.7 vs prehypertension:143.4?14.4 vs hy- pertension:144.3?13.8 g/L,P

Adolescent ; Adult ; Age Distribution ; Child ; Child, Preschool ; Female ; Hepatitis A ; epidemiology ; virology ; Hepatitis A Virus, Human ; pathogenicity ; Hepatitis B ; epidemiology ; virology ; Hepatitis B virus ; pathogenicity ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Socioeconomic Factors ; Young Adult

Objective To study the status and influencing factors on drug therapy compliance for the spinal tuberculosis patients after leaving hospital, so as to advance the corresponding nursing intervention strategies and to consolidate the cure effect. Methods 168 spinal tuberculosis patients in community were investigated by the basic information schedule table, compliance with regular treatment schedule table, the degree of disease cognition questionnaire, and the social support questionnaire. All questionnaires were collected and statistically treated. Results The scores of drug therapy compliance for the spinal tuberculosis pateints after leaving hospital were in a lower level, and the rate of compliance with regular treatment for spinal tuberculosis patients was 46.8%. The drug therapy compliance was affected by the years of age, the degree of disease cognition, the adverse reaction of medicine, the economy condition, the degree of civilization and the degree of social support (P <0.05). The drug therapy compliance was positively correlated with the degree of disease cognition, the economy condition, the degree of civilization and the degree of social support. The drug therapy compliance was negatively correlated with the years of age and the adverse reaction of medicine. Conclusions The druy therapy compliance for the spinal tuberculosis patients out of hospital is generally in a lower level Nursing stuffs should adopt active nursing interventions to raise the drug therapy compliance for spinal tuberculosis patients based on the influencing factors.

Objective To understand patient's self-efficiency sense in fever clinic of first type HIN1 influenza and its influencing factors. Methods Totally 826 patients coming to the fever clinic of our academy were investigated by the general situation questionnaire, the general self-efficacy scale, first type HI NI influenza cognitive questionnaire, the social support rating scale. Results The scores (2.44 +0.63 ) of the general self- efficacy scale by the fevering patients were lower than the norm notably ( P < 0. 05 ). The scores of the general self-efficacy scale were affected by the years of age, gender, marital status, education background, the degree of social support, the degree of the disease cognition and positively correlated with the age, education background, the degree of social support and the degree of the disease cognition( P <0. 05 ). Conclusions The scores of the general self-efficacy scale getting from the levering patients were low generally. Nursing stuffs should understand the state of the self-efficacy sense and analyze the influence factors, adopt positive intervention to help patients improving the self-efficacy sense to strengthen the result of preventing and controlling influenza.

OBJECTIVETo study the effect of Jingjielianqiao Decoction in promoting leg ulcer in rabbits.

METHODSNine adult male New Zealand albino rabbits with chronic leg ulcers were randomized into 3 groups, namely group A treated with Jingjielianqiao Decoction, group B with Shengjiyuhong Decoction, and group C with normal saline. Gross observation of the wounds was carried out regularly for evaluating the changes in the ulcerous area, depth and wound surface excretion. After 3 weeks of treatment, the tissues on the edge of the ulcer were sampled and prepared for routine pathological examination, electron microscopy and immunohistochemistry for vascular endothelial growth factor (VEGF) and CD34. The number of blood vessels and their areas were also recorded.

RESULTSThe wounds showed no significant differences between the 3 groups by gross observation during the treatment, but after completion of the 3-week treatment, routine pathological examination and electron microscopy revealed significant differences between the groups. Immunohistochemistry for VEGF and CD34 yielded comparable results between groups A and B (positive control), but showed significant differences between group C and the other two groups (P<0.01).

CONCLUSIONJingjielianqiao Decoction and Shengjiyuhong Decoction can obviously promote the healing of leg ulcer in rabbits.

Animals ; Antigens, CD34 ; analysis ; Drugs, Chinese Herbal ; therapeutic use ; Immunohistochemistry ; Leg Ulcer ; drug therapy ; metabolism ; pathology ; Male ; Microscopy, Electron ; Phytotherapy ; Rabbits ; Random Allocation ; Skin ; drug effects ; pathology ; ultrastructure ; Vascular Endothelial Growth Factor A ; analysis ; Wound Healing ; drug effects

OBJECTIVETo observe the pharmacodynamics of Jingjielianqiao decoction in promoting the healing of acute radiation-induced skin ulcers in mice.

METHODSSkin ulcers were induced in mice by radiation, and Jingjielianqiao decoction, rivanol or normal saline was applied for the treatment. The swelling of the legs was measured in mice using volumetric method, and the ulcer area after treatment was compared among the 3 groups.

RESULTSNo significant difference was found in the anti-inflammatory effects between Jingjielianqiao decoction group and rivanol group (P>0.05), but a significant difference was noted between Jingjielianqiao decoction group and normal saline group and also between rivanol group and normal saline group (P<0.01). Significant differences were observed in the ulcer healing among the 3 groups (P<0.01).

CONCLUSIONJingjielianqiao decoction can significantly suppress radiation-induced acute inflammation and shows better effect than rivanol in promoting the healing of acute radiation-induced skin ulcer in rats.

Animals ; Drugs, Chinese Herbal ; administration & dosage ; pharmacology ; therapeutic use ; Female ; Phytotherapy ; Radiodermatitis ; drug therapy ; Rats ; Rats, Wistar ; Skin Ulcer ; drug therapy ; etiology ; Wound Healing ; drug effects

OBJECTIVETo elucidate the possible mechanism of oral carcinogenesis and to explore the value of clinical application of the detection of cytokeratin (CK) 19 for oral squamous cell carcinoma (OSCC) patients.

METHODSThe cancerous tissues, para-cancerous tissues and excised lymph nodes were collected from 20 operated patients with OSCC. The patients didn't receive radiotherapy and chemotherapy before hospitalization. The relative expression of CK19 mRNA in those tissues was detected by fluorescent quantitative polymerase chain reaction (FQ-PCR).

RESULTSThe expression of CK19 mRNA in the cancerous tissues was 1.85 and 1.66 times higher than that in normal oral mucosa and in para-cancerous tissues, respectively. The expression of CK19 mRNA in lymph nodes from 9 patients with OSCC was positive and the positive rate was 45% (9/20). The positive rate of CK19 mRNA in all lymph nodes from 9 patients with OSCC was 81.8% (18/22), and the positive rate of CK19 mRNA in all lymph nodes from 20 patients with OSCC was 41.9%(18/43). CK19 mRNA level in the cancerous tissues relative to para-cancerous tissues and normal oral mucosa of the patients whose CK19 mRNA expression was positive was lower than that of the patients whose CK19 mRNA expression was negative in lymph nodes, respectively.

CONCLUSIONThe possible reason that the expression of CK19 mRNA in the cancerous tissues was higher than that in para-cancerous tissues and normal oral mucosa was that the CK19 synthesis in cancerous tissues increased obviously. The detection of CK19 mRNA in lymph nodes was regarded probably as one of the markers for detecting OSCC micrometastasis in lymph nodes. The detection of CK19 mRNA in lymph nodes by FQ-PCR was more sensitive than hematoxylin-eosin staining in diagnosing OSCC micrometastasis.

Carcinoma, Squamous Cell ; Female ; Humans ; Keratin-19 ; Male ; Middle Aged ; Mouth Mucosa ; Mouth Neoplasms ; RNA, Messenger

Disease Management ; Humans ; Pulmonary Disease, Chronic Obstructive ; diagnosis ; drug therapy ; surgery