1.A new shockable rhythm detection algorithm for AED.
Cong LIU ; Hai-Lang SONG ; Xiao-Mei WU ; Zu-Xiang FANG
Chinese Journal of Medical Instrumentation 2009;33(5):320-322
EMG, This paper introduces a slope variability algorithm which uses the CU Database and the AHA Database. The sensitivity, specificity, positive predictivity and accuracy are calculated and these values are compared with the results from two earlier detection algorithms. The results show this algorithm is more effective and fast than other algorithms.
Algorithms
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Defibrillators
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Electric Countershock
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instrumentation
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Predictive Value of Tests
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Sensitivity and Specificity
2.Method and implementation of real-time QRS-waves detection based on wavelet transform.
Qin XIONG ; Zu-xiang FANG ; Hai-lang SONG ; Xiao-mei WU
Chinese Journal of Medical Instrumentation 2007;31(4):242-270
A method based on wavelet transform has been developed for detecting QRS-waves.The MIT-BIH database is used to evaluate this method, and the accuracy is over 99.5%. Then the method is implanted into the embedded system to implement the real-time detection of ECG. This method has good performances in time-delay and computation.
Algorithms
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Electrocardiography
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methods
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Wavelet Analysis
3.Development of an embedded mobile terminal for real-time remote monitoring of out-of-hospital cardiac patients.
Zhi-min XU ; Zu-Xiang FANG ; Da-Kun LAI ; Hai-Lang SONG
Chinese Journal of Medical Instrumentation 2007;31(3):182-191
A kind of real-time remote monitoring embedded terminal which is combined with mobile communication technology and GPS localization technology, has been developed. The results of preliminary experiments show that the terminal can transmit ECG signals and localization information in real time and continuously, supply a real-time monitoring of out-of-hospital cardiac patients and trace the patients.
Electrocardiography, Ambulatory
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instrumentation
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Telemedicine
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instrumentation
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Telemetry
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instrumentation
4.Dynamic Expressions of Tenascin-C at Different Phases of Atherosclerosis in ApoE-/- Mice
Yan LI ; cheng Jia SONG ; lang Hai YAN ; wen Jun HUANG ; Yu LU ; long Zhan MA ; bin Hai SHI
Chinese Circulation Journal 2017;32(12):1217-1221
Objective: To investigate the dynamic expressions of tenascin-C (TN-C) at different phases of atherosclerosis in ApoE-/-mice. Methods: Our research included in 2 groups: ApoE-/- group, n=50 SPF male mice with ApoE-/- and Control group, n=50 wild male C57BL/6 mice. Atherosclerosis model was established by high fat diet in both groups. The mice were sacrificed at 4, 8, 16, 24 and 32 weeks, blood lipids were examined, pathologic changes of plaque were observed by microscope for quantitative analysis and TN-C expressions in atherosclerosis plaque were measured by immunohistochemistry. Results: Compared with Control group, ApoE-/- group had elevated blood levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C), both P<0.05. In ApoE-/- group, plaque area and the ratio of plaque area/lumen area were increasing upon prolonged modeling time, all P<0.05; TN-C expressions were increasing by progress of atherosclerosis, the highest TN-C expression was found at 32 weeks of modeling (0.49±0.07) which was higher than it was at 8 weeks (0.04±0.02), 16 weeks (0.12±0.03) and 24 weeks (0.21±0.04), all P<0.05. Conclusion: TN-C expression was increasing with plaque progress which might be related to the development of atherosclerosis and plaque instability.
5.Structural changes of gut microbiota after gastric bypass in obese patients with type 2 diabetes.
Min LANG ; Ke-Hong ZHENG ; Song-Hua ZENG ; Yuan YANG ; Liang-Ping WU ; Zong-Hai HUANG
Journal of Southern Medical University 2017;37(10):1337-1344
OBJECTIVETo investigate the structural changes inintestinal flora and metabolic changes in type 2 diabetic patients with obesity(BMI≥40 kg/m)by sequencing the 16S rRNA genes.
METHODSStool samples were collected from 4 diabetic patients before and after gastric bypass surgery for extraction of the total DNA. The diversity of the intestinal flora in the samples was investigated by 16S rRNA sequencing. After surgery, the changes in glucose and lipid metabolism were evaluated in the patients, and the changesin body mass index (BMI) and waist to hip ratio were assessed at 3 month intervals.
RESULTSAfter gastric bypass, the patient's BMI, waist to hip ratio, glucose metabolism and lipid metabolism gradually recovered the normal levels. The proportion of Bacteroidetesis increased and the proportions of Firmicutes and Proteobacteria decreased in the intestinal bacteria after the surgery.
CONCLUSIONGastric bypass surgery can effectively alleviate the condition of obese patients with type 2 diabetes and improve the composition of the intestinal flora.
6.Safety and efficacy of polymer-free paclitaxel-eluting microporous stent in real-world practice: 1-year follow-up of the SERY-I registry.
Rui-Yan ZHANG ; Qi ZHANG ; Jin-Zhou ZHU ; Liang-Long CHEN ; Chen-Yun ZHANG ; Xu-Chen ZHOU ; Yong YUAN ; Zhi-Xiong ZHONG ; Lang LI ; Jian QIU ; Wei WANG ; Xi-Ming CHEN ; Zhi-Jian YANG ; Jin-Chuan YAN ; Shao-Liang CHEN ; Yu-Qing HOU ; Yan-Qing WU ; Hai-Ming LUO ; Jian-Ping QIU ; Li ZHU ; Yan WANG ; Guo-Sheng FU ; Jian-An WANG ; Kang-Hua MA ; Yue-Hui YIN ; Dai-Fu ZHANG ; Xue-Song HU ; Guo-Ying ZHU ; Wei-Feng SHEN ; null
Chinese Medical Journal 2011;124(21):3521-3526