2.Effect of Stellate Ganglion Block on Patients with Cerebral Infarction:Report of 36 Cases
Li-hong SHI ; Hai-feng DENG ; Hai-li WANG
Chinese Journal of Rehabilitation Theory and Practice 2008;14(12):1168-1169
Objective To observe the effect of stellate ganglion block on patients with cerebral infarction.Methods36 patients with cerebral infarction were randomly divided into the control group and research group.Both two groups were treated with traditional treatment.The research group was added with stellate ganglion block.ResultsAfter 20 days treatment,the Neuro-function Deficit(NFD) scores of both two groups were significantly lower than that before treatment(P<0.01);but the NFD scores of the research group were significantly lower than that of the control group(P<0.01).The scores of Fugl-Meyer Assessment(FMA) and Barthel Index(BI) of both two groups were significantly higher after treatment(P<0.01);but the scores of FMA and BI of the research group were significantly higher than that of the control group(P<0.01).ConclusionStellate ganglion block can improve the nerve function of patients with cerebral infarction.
3.Intrathoracic drainage in treatment of 43 coal worker's pneumoconiosis patients with pleural effusion and pneumothorax.
Wei GAO ; Feng LI ; Shu-hai WU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(10):618-619
Aged
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Anthracosis
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complications
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Catheterization
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Drainage
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methods
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Humans
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Male
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Middle Aged
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Pleural Effusion
;
etiology
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therapy
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Pneumothorax
;
etiology
;
therapy
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Retrospective Studies
4.A case report of dental abnormality and prosthetic treatment of Satoyoshi syndrome.
Jian LI ; Ting JIANG ; Hai-Lan FENG
Chinese Journal of Stomatology 2008;43(4):213-215
Adolescent
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Alopecia
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diagnosis
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therapy
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Bone and Bones
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abnormalities
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Denture, Complete, Upper
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Diarrhea
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diagnosis
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therapy
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Female
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Humans
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Spasm
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diagnosis
;
therapy
5.Establishment of euglycemic clamp technique in beagle dogs
Bulletin of The Academy of Military Medical Sciences 2010;34(1):40-42,50
Objective To establish a euglycemic clamp technique in beagle dogs. Methods The euglycemic clamp technique was applied in healthy beagle dogs and the blood glucose, insulin, C-peptide, insulin and glucagon were monitored during the clamp. Results The blood glucose was controlled within the basal level.The coefficient of variation was less than 5% during the clamp. The serum insulin concentration finally reached(40.0±3.8)mIU/L stably and a significant inhibition was shown in endogenous insulin by the determination of C-peptide. But there was no significant increase in serum glucagon compared with basal values.Conclusion Methodology confirmed that the euglycemic clamp technique is successful in beagle dogs and can be applied in the study of pharmacodynamics of insulin preparations.
6.Analysis of the therapeutic effects of cataract extraction and intraocular lens implantation in silicon oil stored eyes with proliferative diabetic retinopathy
Wen-Si LI ; Feng ZHANG ; Hai LU ;
Ophthalmology in China 1993;0(04):-
Objective To compare the postoperative effect of pars plana vitrectomy,phacoemulsification and intraoeular lens (IOL)implantation with silicon oil removed,phacoemulsification and IOL implantation.Design A retrospective case-control study.Par- ticipants 91 cases(104 eyes)of proliferative diabetic retinopathy with tractive retinal detachment or vitreous hemorrhage were per- formed cataract surgery with IOL implantation.Methods All patients were followed up average 6 months,in whom 52 eyes with pars plana vitrectomy,phacoemulsification and IOL implantation(combined group),and the other 52 eyes with silicon oil removed,pha- coemulsification and IOL implantation(sequential group).The differences of the postoperative visual acuity and inflammatory reactions of the anterior chamber between the two groups were analyzed.Main outcome measures Visual acuity and inflammatory reactions of the anterior chamber.Results There were 14/52 eyes with best corrected visual acuity more than 0.1 in combined group and 8/52 eyes in the sequential group after the surgeries(X~2=-6.87,P=0.07) .Corneal edema happened in 16/52 eyes in combined group and 6/52 eyes in sequential group 1 week after the surgeries(X~2=11.53,P=0.001).Keratic precipitate happened in 20/52 eyes in combined group and 9/52 eyes in sequential group after the surgeries(X~2=5.79,P=0.019) .Conclusions The incidence of postoperative anterior chamber in- flammation is higher in Phacoemulsification combined with pars plana vitrectomy group.
7.Clinical observation of perioperative continuing aspirin therapy in tooth extraction surgery in patients with coronary heart disease
Ronghua LI ; Gang REN ; Hai FENG ; Yumin LI ; Kai YIN
Chinese Journal of Geriatrics 2014;33(10):1045-1048
Objective To investigate the influence of perioperative continuing aspirin therapy on tooth extraction surgery in elderly patients with coronary heart disease.Methods A total of 926 patients with coronary heart disease who required tooth extraction were enrolled in this study.Among them,241 patients discontinued aspirin therapy before tooth extraction,685 patients continued aspirin therapy before tooth extraction.The entering rate of operation was evaluated.100 patients continuing aspirin and 100 patients discontinuing aspirin were randomly selected.Systemic pressure,diastolic pressure and heart rate before and after tooth extraction were detected.100 matched healthy elderly patients were selected as normal control group.Multivariate logistic regression analysis was used to estimate the risk for tooth extraction.Results The entering rate of operation was 67.9% (131 cases) in 193 patients with angina pectoris discontinuing aspirin therapy and 82.1 % (312 cases) in 380 patients with angina pectoris continuing aspirin therapy (x2 =14.77,P<0.01).The entering rate of operation was 41.7% (20 cases) in 48 patients undergoing coronary revascularization and discontinuing aspirin therapy,and 80.7% (312 cases) in 305 patients undergoing coronary revascularization and continuing aspirin therapy (x2=33.95,P<0.01).The changes in systolic blood pressure before versus after dental extraction had a significant difference between the discontinuing aspirin group and control group [(15.9±5.5) mmHg vs.(12.2±4.7)mmHg,P<0.05,1 mmHg=0.133 kPa],while had no significant difference between the continuing aspirin group and control group [(13.6±4.5) mmHg vs.(12.2±4.7) mmHg,P>0.05].There were no significant differences in changes in diastolic blood pressure and heart rate in the intraoperative period between the patients and controls (P>0.05).The bleeding rate in patients continuing aspirin therapy was not significantly different as compared with control group (P> 0.05).Multivariate logistic regression analysis revealed that perioperative discontinuing aspirin therapy remained the second significant risk factor for tooth extraction.Conclusions Preoperative administration of aspirin should be continued in dental extraction surgery in elderly patients with coronary heart disease.
8.Relationship between the expression of leukemia stem cell immunophenotype and the treatment efficacy and prognosis.
Hai-bo ZHU ; Ming-feng ZHAO ; Yu-ming LI
Chinese Journal of Hematology 2012;33(1):58-60
Adolescent
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Adult
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Aged
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Aged, 80 and over
;
Child
;
Female
;
Humans
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Immunophenotyping
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Leukemia
;
diagnosis
;
immunology
;
therapy
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Male
;
Middle Aged
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Neoplastic Stem Cells
;
immunology
;
Prognosis
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Treatment Outcome
;
Young Adult
9.Progress in the study of near-infrared fluorescent probes for the detection of β-amyloid deposition in Alzheimer's disease.
Lei DU ; Hai-wei FENG ; Yu-yan LI
Acta Pharmaceutica Sinica 2015;50(5):528-534
Alzheimer's disease (AD) is the most common cause of cognitive impairment in older people. With the aging of society is more and more serious, AD caused great burden to patients and society. A β is a classical biomarker of AD, which has been widely used in clinical diagnosis of AD patients. Compared with positron emission tomography (PET) and single photon emission computed tomography (SPECT), near infrared fluorescence imaging has many advantages including highly sensitive, non-invasive, safety and inexpensive. Therefore, many research groups have focused on developing the molecular probes of near-infrared fluorescence (NIRF) imaging. In this article, we will review the progress of the probes of NIRF.
Alzheimer Disease
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diagnosis
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Amyloid beta-Peptides
;
analysis
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Fluorescence
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Fluorescent Dyes
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Humans
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Molecular Probes
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Positron-Emission Tomography
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Spectroscopy, Near-Infrared
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Tomography, Emission-Computed, Single-Photon
10.The value of procalcitonin compared to C-reactive protein and blood white cell count in early detection of sepsis following percutaneous nephrolithotomy
Guizhong LI ; Libo MAN ; Hai WANG ; Feng HE
Chinese Journal of Urology 2017;38(1):42-46
Objective To assess the value of procalcitonin (PCT) levels compared to C-reactive protein (CRP) levels and blood white cell count in early detection of sepsis following percutaneous nephrolithotomy.Methods This prospective observational study included 91 patients,including 59 male patients and 32 female patients,undergoing percutaneous nephrolithotomy between April 2014 and October 2015.Their mean age was (54 ± 15)years old,ranging 15 to 88 years old.The average size of stone was (20.9 7.0) am.Those patients were classified into two groups,based on whether the postoperative sepsis existed.In this group,51 cases were concluded in the sepsis group and 40 in the non-sepsis group.A statistically significant difference between patients with and without sepsis was found in the hydronephrosis (44 vs.25,P =0.009),urine white cell count [(402 ± 970) / μ1 vs.(70 ± 171) / μ1,P < 0.01],positive urine culture(36 vs.20,P < 0.05),positive pelvic urine culture (22 vs.5,P =0.001).There was not any significant difference in sex,age,size of calculi and blood culture between patients with and without sepsis (P > 0.05).Blood white blood cell count,CRP,and PCT were measured in patients with an acute onset of sepsis.Diagnostic accuracy of PCT values was analyzed by the receiver operating characteristics (ROC) curve.Results A statistically significant difference between patients with and without sepsis was found in the PCT [(7.43 ± 10.15)μg/L vs.(0.14 ± 0.10)μg/L,P < 0.01] and blood white cell count [(14.18 ± 6.47) × 109/L vs.(11.22±4.22) × 109/L,P <0.05].There was not any significant difference in CRP [(64.93 ± 68.60) mg/ml vs.(70.76 ± 53.36) mg/ml,P > 0.05] between patients with and without sepsis.ROC curve analysis showed that blood white cell count and PCT concentrations had similar predictive values for the development of sepsis (area under the curve,0.78 and 0.90,respectively) with the best cut-off values of blood white cell count for 12 × 109/L (sensitivity 50%,specify 88%) and 0.5 μg/L (sensitivity 64%,specify 100%)for PCT.54 cases were performed blood culture,which showed positive in 12 cases and negative in 42 cases.The significant difference of PCT level could be noticed in two groups [(16.99 ± 11.64) μg/ L vs.(3.77 ± 7.23) μg/ L,P < 0.05)].No significant difference was found in CRP,Blood white cells count among those groups (P < 0.05).ROC curve analysis showed that PCT concentrations had predictive values for the positive blood culture (area under the curve,0.80) with the best cut-off values of 8 μg/L (sensitivity 71%,specify 88%) for PCT.Conclusions PCT was a useful marker for the diagnosis of the sepsis after percutaneous nephrolithotomy as compared with WBC and CRP.