OBJECTIVETo evaluate the early clinical and radiographic outcome of scaphoid non-unions treated with Acutrak headless compression screw.

METHODSFrom January 2008 to July 2011,21 patients with scaphoid non-union were treated in our department. There were 18 males and 3 females with a mean age of (23.6 +/- 4.6) years; 12 cases were on right hand and 9 were on left. According to Herbert-Fisher classification, there were 10 cases with type D1, 7 cases with type D2, 3 cases with type D3, and 1 case with type D4. The mean time from injury to operation was (12.4 +/- 2.7) months. All patients were treated with Acutrak headless compression screw fixation (6 cases received 2 screws fixation, 15 cases received 1 screw fixation, and Matti-Russe bone grafting was applied in 7 cases). The carpal height, the scaphoid index and changes of the scapholunate angle were assessed before and after the operation. Range of motion and grip strength were recorded and the wrist function was assessed according to the Patient-Rated Wrist Evaluation (PRWE).

RESULTSAverage duration of follow-up was (21.3 +/- 3.6) months. All the patients attained radiological union in a mean time of (13.3 +/- 2.4) weeks following the operation. No obvious complications were recorded. The surgical treatment allowed the preoperative mean scaphoid index of 0.61 +/- 0.13 and the preoperative mean scapholunate angle of (59.4 +/- 6.8) degree to be improved to 0.69 +/- 0.10 and (44.3 +/- 8.2)degree postoperatively, respectively. There was a substantial improvement in grip strength and pain amelioration after surgery. The preoperative mean PRWE score of 45.2 +/- 4.7 was improved to 76.1 +/- 5.2 postoperatively. All patients returned back to the original work,the average time from surgery to work was (6.0 +/- 1.1) months.

CONCLUSIONFor scaphoid non-unions, Acutrak headless compression screw fixation can provide anatomical reduction, provide satisfactory results with a high union rate, well return of function and minimal complications in the early stage.

Adolescent ; Adult ; Bone Screws ; Female ; Fracture Fixation, Internal ; Fractures, Ununited ; surgery ; Humans ; Male ; Range of Motion, Articular ; Scaphoid Bone ; injuries ; physiopathology ; surgery ; Treatment Outcome ; Wrist Injuries ; physiopathology ; surgery ; Wrist Joint ; physiopathology ; surgery ; Young Adult

In this paper, the process performance indexes (PPIs) P(p) and P(pk) were introduced and applied to evaluate the process capability and quality consistence of Chinese medicine products. The historical quality analysis data of Qingkailing injection were collected and taken as the research object. The confidence intervals of P(p) and P(pk) were estimated based on the Bootstrap sampling methods. Results showed that the value and width of the confidence interval P(p) of were smaller that of P(pk) suggesting that the P(pk) index was more sensitive than P(p) in process capability analysis. Within the production period concerned, the P(pk) values estimated from different quality indexes of Qingkailing injection, such as baicalin, cholic acid, geniposide and total nitrogen, were 1.122, 2.055, 1.564 and 0.891, respectively. It could be found that the cholic acid had the highest process capability, followed by the geniposide and baicalin. The total nitrogen had the lowest process capability, indicating that it is necessary to reinforce the quality management of total nitrogen related manufacturing processes. The case studies demonstrate the effectiveness and feasibility of PPIs, which are convenient to be used in production practice of Chinese medicine.
Chemistry, Pharmaceutical ; methods ; standards ; Drugs, Chinese Herbal ; chemistry ; standards ; Injections ; Quality Control

The compound that distributes in the herbs with one common effect was named as "co-effect compound" (CEC). The CECs of three traditional Chinese medicine(TCM) effects, purgative, relieving pain and clearing heat, had been found and studied. A strong corresponding relationship was found between the pharmacological activities of CECs and the TCM effect they belong to. The study shows that it may be a feasible method to connect traditional effect of TCM with modem pharmacological activity.
Anthraquinones ; isolation & purification ; pharmacology ; Anti-Inflammatory Agents, Non-Steroidal ; pharmacology ; Cathartics ; pharmacology ; Drugs, Chinese Herbal ; isolation & purification ; pharmacology ; Flavonoids ; isolation & purification ; pharmacology ; Medicine, Chinese Traditional ; Plants, Medicinal ; chemistry

Objective:To evaluate the early clinical and radiographic outcome of scaphoid non unions treated with Acu-trak headless compression screw. Methods:From January 2008 to July 2011,21 patients with scaphoid non union were treated in our department. There were 18 males and 3 females with a mean age of (23.6±4.6) years;12 cases were on right hand and 9 were on left. According to Herbert-Fisher classification,there were 10 cases with type D1,7 cases with type D2,3 cases with type D3,and 1 case with type D4. The mean time from injury to operation was (12.4±2.7) months. All patients were treated with Acutrak headless compression screw fixation (6 cases received 2 screws fixation,15 cases received 1 screw fixation,and Matti-Russe bone grafting was applied in 7 cases). The carpal height,the scaphoid index and changes of the scapholunate an-gle were assessed before and after the operation. Range of motion and grip strength were recorded and the wrist function was assessed according to the Patient-Rated Wrist Evaluation (PRWE). Results:Average duration of follow up was (21.3±3.6) months. All the patients attained radiological union in a mean time of (13.3±2.4) weeks following the operation. No obvious complications were recorded. The surgical treatment allowed the preoperative mean scaphoid index of 0.61±0.13 and the pre-operative mean scapholunate angle of (59.4±6.8)° to be improved to 0.69±0.10 and(44.3±8.2)° postoperatively,respectively. There was a substantial improvement in grip strength and pain amelioration after surgery. The preoperative mean PRWE score of 45.2 ±4.7 was improved to 76.1 ±5.2 postoperatively. All patients returned back to the original work ,the average time from surgery to work was (6.0±1.1) months. Conclusion:For scaphoid non unions,Acutrak headless compression screw fixation can provide anatomical reduction,provide satisfactory results with a high union rate,well return of function and minimal complica-tions in the early stage.

OBJECTIVETo observe the correlation relationship between acupuncture at Dicang (ST 4), Hegu (LI 4) and Houxi (SI 3) on the affected side of peripheral facial paralysis patients and activated areas in brain functional areas and central regulation mechanism of acupuncture at Hegu (LI 4) treatment.

METHODSEighteen cases with left peripheral facial paralysis were randomly divided into a Hegu group, a Dicang group and a Houxi group, 6 cases in each group. They were treated with electroacupuncture at left Dicang (ST 4), Hegu (LI 4) and Houxi (SI 3), respectively, and were examined with fMRI covering the whole brain at the same time. The fMRI data was analyzed by SPM software.

RESULTSIt was found that the left precentral gyrus area and the left postcentral gyrus area were activated when electroacupuncture at left Hegu (LI 4), and the right precentral gyrus area and the bilateral postcentral gyrus area were activated when electroacupuncture at left Dicang (ST 4), and there was no activated area at precentral gyrus area and post central gyrus area when electroacupuncture at left Houxi (SI 3).

CONCLUSIONThe sensory importation information from Hegu (LI 4) and Dicang (ST 4) can converge and coincide in the brain and may influence each other.

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Aged, 80 and over ; Brain ; diagnostic imaging ; physiopathology ; Facial Paralysis ; diagnostic imaging ; physiopathology ; therapy ; Female ; Human Body ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Radiography ; Young Adult

Higher education has gradually become essential in the economical society with the coming knowledge economic time. Cultivation of innovative dental talents is highly requested by modernization of China. Textbooks are crucial in cultivating high quality students of stomatology. A completely new epoch proposition appeared on how to construct an innovative teaching textbook system. The countermeasures, which are aiming at such aspects as the textbook evaluation system, author groups and textbook systems, are discussed in this paper.
Books ; China ; Humans ; Oral Medicine ; Students

Objective To detect EIA factor expression in human rectal cancer and normal tissue and to determine whether it is correlated with invasion and metastasis of human rectal cancer. Methods Real- time RT-PCR was used to detect E1AF expression in matched rectal cancers and normal tissues from g6 in- patients.Results Among the 86 rectal cancer samples tested,55 cases E1AF mRNA overexpression was ob- served. The mRNA expression of E1AF in the sample group was remarkably different from that in the control group.In carcinomas,E1AF mRNA expression correlated significantly with histological type,depth of inva- sion,lymph node and distant metastasis and advanced Duke stage.Conclusion E1AF is correlated signifi- cantly with invasion and metastasis of human rectal cancer and may be an important factor in the invasion and metastasis.

OBJECTIVETo investigate the sexual function and the quality of sexual life in patients with chronic prostatitis (CP), and to analyze the correlated factors and their influence on the quality of life (QOL) of the CP patients.

METHODSWe randomly selected 148 CP patients as the CP group and 71 healthy men as controls, asked them to fill out a questionnaire on sexual function and the quality of sexual life, obtained their scores on NHI-CPSI, and comparatively analyzed the results. We also made analyses on the influence of age, disease course, CP symptom scores and EPS level on sexual function and the quality of sexual life, as well as the impact of CP symptoms, sexual dysfunction and sexual life quality on the QOL of the CP patients.

RESULTSNo retro-ejaculation was found in either of the two groups. The mean score on sexual function and sexual life quality was 38.1 +/- 7.9 and 47.8 +/- 3.1 in the CP and the control group, respectively, with statistically significant differences (P < 0.05). Compared with the controls, the CP patients showed significantly decreased scores on libido, erectile function, ejaculation, orgasm frequency, self-confidence in sexual life, sexual satisfaction, and the partners' orgasm frequency and sexual satisfaction (P < 0.05). The indexes of sexual function and the QOL score were significantly correlated with CP symptoms, but not with the disease course and the WBC and lecithin counts in the prostatic fluid. The age of the patients was significantly correlated with the score of libido but not with other indexes of sexual function. CP symptoms, including pain, micturition and reduced sexual function and sexual life quality, along with the decreased orgasm frequency and sexual satisfaction of the patients' spouses, remarkably influenced the patients' QOL.

CONCLUSIONCP symptoms significantly decrease the indexes of sexual function of the patients and, in turn, their sexual life quality and QOL. Sexual dysfunction and reduced sexual life quality of CP patients are significantly correlated with CP symptoms, but not with the course of the disease, the age of the patient and the results of EPS detection.

Adult ; Case-Control Studies ; Erectile Dysfunction ; etiology ; Humans ; Male ; Middle Aged ; Prostatitis ; physiopathology ; Quality of Life ; Sickness Impact Profile ; Spouses ; Surveys and Questionnaires ; Young Adult

OBJECTIVETo investigate the oral health status of undergraduate university students and to guide their oral hygiene behaviors.

METHODS3516 college students in Northwest University for Nationalities were investigated in this study according to the criterion issued by World Health Organization (WHO) on the basic methods of oral health investigation in 1997.

RESULTSThe caries prevalence rate among the students investigated was 47.87%. The average decayed teeth were 1.29. The obturation rate of caries was 20.42%. The students came from city showed significant higher caries rate than those from countryside, and so did the female students compared with the male students. Dental calculus rate was 79.78%. The dental segments related were 3.75. The worst situation was among male students and students from countryside. The examined rates were 53.30% of crowded incisor, 42.58% of maximum upper-incisor anomaly, 50.60% of the maximum lower-incisor anomaly and 31.09% of molar malposition, respectively. More rates of dentofacial anomalies showed no differences of significance between different area and gender.

CONCLUSIONIn general, the oral health status of the college students are not ideal. It is necessary to advocate early examination, early prevention and early treatment among the students in university.

DMF Index ; Dental Caries ; Female ; Health Status ; Humans ; Male ; Oral Health ; Oral Hygiene ; Prevalence ; Students ; Universities

Adolescent ; Encephalocele ; etiology ; Humans ; Male ; Meningocele ; etiology ; Neurofibromatosis 1 ; complications ; diagnosis ; therapy ; Orbital Diseases ; etiology