The authors observed 4 cases of retinitis punctata albescens presented in a family, namely, a sister and 3 brothers of 6 siblings. Typical fundus findings were found in all four patients. Under ordinary illumination, the perripheral visual field was within the limit of normal, but concentrically contracted in 5 to 30 degrees under the reduced illumination.
Humans ; Lighting ; Retinitis* ; Siblings ; Visual Fields

The use of succinylcholine chloride(Anectin(R)) prior to intubation, can cause increased contracture of ocular muscles. Therefore the authors studied the change of the squint angle under general anesthesia using pancronium bromide (Myoblock(R)) in 81 horizontal strabismus patients who had no neurologic disease and mechanical restrictions of eye movement. We used the alternative cover test and Krimsky method to measure the eye position under general anesthesia.
Anesthesia ; Anesthesia, General* ; Contracture ; Eye Movements ; Humans ; Intubation ; Muscles ; Strabismus* ; Succinylcholine

Glaucoma screening is an important means of detecting early cases of glaucoma. It is particularly valuable if targeted either at groups who otherwise do not have access to the health care system or at groups who have the risk factors for glaucoma such as aging, being male and having a medical history of diabetes or vascular diseases. We conducted glaucoma screenings by tonometry and direct ophthalmoscopy in the outpatient department of ophthalmology at Korea University Haewha Hospital and in the homes for the aged that are located in Seoul between Sep. 1987 and Sep. 1989. A total of 282 subjects were screened in the outpatient department and 198 subjects were screened in the homes for the aged. Referral rate was 6.7% and 3.0%, respectively. Groups who have the risk factors showed greater referral rates than groups who have not, but they are not statistically significant(p>0.05).
Aged ; Aging ; Delivery of Health Care ; Glaucoma* ; Homes for the Aged ; Humans ; Korea ; Male ; Manometry ; Mass Screening* ; Ophthalmology ; Ophthalmoscopy ; Outpatients* ; Referral and Consultation ; Risk Factors ; Seoul ; Vascular Diseases

Glaucoma screening is an important means of detecting early cases of glaucoma. It is particularly valuable if targeted either at groups who otherwise do not have access to the health care system or at groups who have the risk factors for glaucoma such as aging, being male and having a medical history of diabetes or vascular diseases. We conducted glaucoma screenings by tonometry and direct ophthalmoscopy in the outpatient department of ophthalmology at Korea University Haewha Hospital and in the homes for the aged that are located in Seoul between Sep. 1987 and Sep. 1989. A total of 282 subjects were screened in the outpatient department and 198 subjects were screened in the homes for the aged. Referral rate was 6.7% and 3.0%, respectively. Groups who have the risk factors showed greater referral rates than groups who have not, but they are not statistically significant(p>0.05).
Aged ; Aging ; Delivery of Health Care ; Glaucoma* ; Homes for the Aged ; Humans ; Korea ; Male ; Manometry ; Mass Screening* ; Ophthalmology ; Ophthalmoscopy ; Outpatients* ; Referral and Consultation ; Risk Factors ; Seoul ; Vascular Diseases

Choristoma is a congenital abnormal growth of tissue with components which are not characteristic of the location. Most choristomas often affect tissues of one germinal layer, mainly ectodermal layer, but complex choristoma contains two or more choristomatous tissues(ectodermal, mesodermal and rarely entodermal tissue) except lacking pilosebaceous apparatus. We experienced a case of large bilateral saccular complex choristomas including scleral and episcleral cartilage in the upper part of cornea, limbus and sclera, which was confirmed histopathologically.
Cartilage* ; Choristoma* ; Cornea ; Ectoderm ; Mesoderm ; Sclera

The tendency toward significantly higher mean tensions in myopic eyes compared with eyes with emmetropia and hyperopia has been believed. The patients with high myopia have an unusually high risk of the development of open angle glaucoma. But there is little information in the literature concerning the range of refractive error in relation to intraocular pressure. This study was designed to provide this information in Koreans and to assess the possible prognostic value of the refraction in glaucoma. The results of this study were as follows: 1. The mean IOP of all the patient were 15.29 +/- 2.61mmHg. 2. The mean IOP of emmetropic patients with +2.0 to -2.0 diopters, myopic patients with -2.25 to -4.75 diopters, and high myopic patients with greater than -5.0 diopters were each 14.99 +/- 2.62mmHg, 5.64 +/- 2.38mmHg, 16.21 +/- 2.56mmHg, respectively, suggesting that as the degree of myopia became higher, so did the IOP became greater, as supported by a statistical analysis showing significance(p<0.001). 3. The mean IOP of hyperopic patients with greater than +0.5 diopters, emmetropic patients with +0.25 to -0.25 diopters, and myopic patients with greater than -0.5 diopters were each 14.41 +/- 2.61mmHg, 14.94 +/- 2.57mmHg, and 15.60 +/- 2.56mmHg, respectively, suggesting that as the refractive error showed a myopic status, it was accompanied by an increase of IOP, as was also supported by the statistical analysis showing significance(p<0.001). 4. In correlating sex with IOP, it was found that both sexes showed an increase of IOP as the refractive status changed from hyperopia to myopia, also supported by a significant statistical analysis(p<0.001). 5. In correlating age with IOP, each age group showed a general increase in IOP as the refractive status changed from hyperopia to myopia. As the age increased, however, it was not accompanied by an increase in IOP(p<0.001). 6. As the Cup/Disk ratio increased the mean IOP also tended to increase; this finding, however, showed no significance in the statistical analysis(p>0.01).
Emmetropia ; Glaucoma ; Glaucoma, Open-Angle ; Humans ; Hyperopia ; Intraocular Pressure* ; Myopia ; Refractive Errors

Reducing inflammation after photo refractive keratectomy may decrease postoperative pain and reduce corneal haze intensity. We evaluated the effect of the therapeutic lens(T-lens) and collagen shield on stromal inflammation. Adult New Zealand white rabbits were subjected to excimer laser PRK. Polymorphonuclear leukocytes(PMNs) of ablated corneal stroma were counted 10 hours after surgery with a microscope. The number of PMNs in the central cornea was lower in the T-lens group (29.77 +/- 11.6) and collagen shield group(36.77 +/- 5.9) than in the tarsorrhaphy group (75.33 +/- 14.6). Of all the groups, the eyes which were left unpatched showed the most marked infiltration of PMNs into the wound(226.83 +/- 18.2). The T-lens and collagen shield may reduce postoperative corneal haze intensity better than a pressure patch by suppression of stromal inflammation.
Adult ; Collagen* ; Cornea ; Corneal Stroma ; Humans ; Inflammation* ; Lasers, Excimer ; Pain, Postoperative ; Photorefractive Keratectomy* ; Rabbits

Hypotony and choroidal detachment have been found to be the most common complication after trabeculectomy, with a mean onset time of 5.6 days. We experienced five eyes of four patients with glaucoma, which developed a flat anterior chamber, hypotony, and choroidal detachment two to nine days after technically uncomplicated trabeculectomy. After treatment with topical and systemic corticosteroids and mydriatic-cycloplegic eyedrops, four of five eyes showed clinical improvement within six days. The one remaining eye eventually improved after surgical drainage of the choroidal detachment and reformation of the anterior chamber performed on the seventh postoperative day.
Adrenal Cortex Hormones ; Anterior Chamber ; Choroid* ; Drainage ; Glaucoma ; Humans ; Ophthalmic Solutions ; Trabeculectomy*

This study analyzed various aspects of what glaucoma patients think about their quality of life(QOL), knowledge of glaucoma, and compliance to treatment. For the study, survey and multifactorial analysis were performed in 165 patients in 10 subject with 60 questions. After the diagnosis of glaucoma, 25.5% of patients were not satisfied with their life compared with 7.3% of them before the diagnosis. Life satisfaction could be decreased from 3.76 point in Likert scale before the diagnosis to 3.07 point after the diagnosis. Life satisfaction decreased significantly in the highly educated group, in the upper or lower income group, and in those who thought as though they were generally healthy. Beside these results, 87.3% of patients were afraid of losing their vision, 78.2% of the patients who had not been operated preferred medical treatment to surgery.
Compliance ; Diagnosis ; Glaucoma* ; Humans ; Quality of Life*

The purpose of glaucoma filtering surgery is to maintain low intraocular pressure byoontinuous filtration of aqueous humor. Filtration failure commonly results from scarring at the surgical site. Fibroblast plays an important role in the scarring process. Mitomycin C and 5-fluorouracil are the antimetabolites capable of inhibiting fibroblast proliferation. In this animal experiment, the authors studied electron microscopically the effect of Mitomycin C and 5-fluorouracil on the fibroblast proliferation at the surgical site. Posterior sclerectomy was performed to 9 eyes of 9 normal rabbits. Postoperatively, 3 eyes recieved subconjunctival injection of Mitomycin C, 3 eyes 5-fluorouracil and 3 eyes normal saline as a control. Additional one eye of a rabbit was used for observation of normol fibroblast. Animals were killed two days, four days, six days following surgery at the time of 12 hours after the last injection. Globes were immediately removed and processed for transmission electron microscopic examination. The results were as follows; 1. Normal fibroblasts in episclera showed dilated cisternae of rough endoplasmic reticulum (RER). 2. Two days after operation, the fibroblasts were slightly activated. 3. Four days after operation, cytoplasmic organelles in fibroblasts were more activated. 4. Six days after operation, secreting forms of fibroblast were visible. The fibrillar materials of moderate electron density pooled in cisternae of RER, and the filamentous elements were in the periphery of the cytoplasm. 5. In Mitomycin C treated group, there was no remarkable change in the cytoplasmic organelles, but some dilation of RER was noted four days after operation. 6. In 5-fluorouracil treated group, there was the same feature as in Mitomycin C group, but milder. 7. Conclusively, Mitomycin C and 5-fluorouracil are considered effective on the inhibition of fibrogenesis with lowering of fibroblastic activity.
Animal Experimentation ; Animals ; Antimetabolites ; Aqueous Humor ; Cicatrix ; Cytoplasm ; Endoplasmic Reticulum, Rough ; Fibroblasts ; Filtering Surgery* ; Filtration ; Fluorouracil ; Glaucoma* ; Intraocular Pressure ; Mitomycin* ; Organelles ; Rabbits