15 experimental dogs with stainless steel plates and screws fixed in the femur were enrolled into a controlled study to assess histological outcome manifested surrounding the sites of intervention. Plates and screw were firmly attached to the bone. No abnormal reaction was observed macroscopically and microscopically. No inflammatory cells were found after a 45, 90, 135, and 180 days follow-up. The structure and the thickness of the connective membrane in contact with the fixed material had a tendency to become more and more stable. From the day 90, no differences were noted between the group of experimental animals and the control subjects using Chinese SMIC material.
Femoral Fractures ; Bone Screws