Among the transfusion reaction, the hemolytic reaction due to mismatched blood transfusion is a fatal complication. After immediate fatal disaster, the renal complication is still life threatening and so its prevention and management are very important. We experienced five cases of acute renal failure and, two of five patients were developed at the SNU hospital and the remainders were transfered to the SNU hospital from local hospital. Two of five patients were showed oliguric renal failures and the remamders were showed non-o-liguric renal failures. All five patients were discharged without complication. We summerize the labaratory data of the five patients during hospitalization and together reviewed with the literatures.
Acute Kidney Injury* ; Blood Group Incompatibility ; Blood Transfusion* ; Disasters ; Hospitalization ; Humans ; Renal Insufficiency

An attempt was made to correlate the incidence of muscle pain following the administration of succinyIcholine and its prevention by prior administration of gallamine or d-tubocurarine. The overall incidence of pain after use of succinylcholine was 29 per cent. The prior injection of d-tubocurarine (0. 05 mg/kg) or gallamine (0. 3 mg/kg) completely pervented the muscle pain. It is presumed that d-tubocurarine or gallamine protects the patients from muscle pain by preventing a portion of the injected succinylcholine from depolarizing the muscle fibers.
Clinical Study* ; Gallamine Triethiodide ; Humans ; Incidence ; Myalgia ; Succinylcholine* ; Tubocurarine

It was presented the precise technique of percutaneous radial-artery catheterization with testing methods for assessment of status in the collateral circulation of the hand, and also presented continuous measurement of arterial blood pressure with connecting to Arenoids blood pressure manometer for blood pressure and commented the easiness numerous arterial blood samplings for the critically illed patients without pain.
Arterial Pressure ; Blood Pressure ; Catheterization* ; Catheters* ; Collateral Circulation ; Hand ; Humans

Ms report shows that hydroxyl radical, generated by a Fenton reaction involving adenosine 5'-diphosphate/Fe2+ complex (5-15 micrometer) and H2O2 (2 micrometer), induced differentiation of HL-60 cells in a dose- and time-dependent manner. This is evidenced by the increases in 12-O-tetradecanoylphorbol 13-acetate- and fMLP-stimulated superoxide production capability. The cells exposed to hydroxyl radical for defined periods (24~96 hr) continued to differentiate even after the hydroxyl radical generating system had been removed. The differentiated cells displayed fMLP-stimulated calcium mobilization and increased expression of myeloid-specific antigen CD11b and CD14. The extent of the differentiation was markedly reduced by desferrioxamine (100micrometer), dimethylthiourea (5 mM), N,N'-diphenyl-1,4-phenylenediamine (2 micrometer), and N-acetyl-L-cysteine (5 mM). The induction of differentiation by hydroxyl radical was enhanced by 3-isobutyl-1-methylxanthine (200 micrometer) and Ro-20-1724 (8 micrometer), and inhibited by dipyridamole (2 micrometer). These results suggest that hydroxyl radicals may induce commitment of HL-60 cells to differentiate into more mature cells of myelomonocytic lineage through specific signal-transduction pathway that is modulated by phosphodiesterase inhibitors.
1-Methyl-3-isobutylxanthine ; Acetylcysteine ; Adenosine ; Calcium ; Deferoxamine ; Dipyridamole ; HL-60 Cells* ; Humans ; Hydroxyl Radical ; Phosphodiesterase Inhibitors* ; Superoxides