1.Discriminant Factors of Attitude Pattern toward Sexual Violence of College Women.
Korean Journal of Women Health Nursing 2009;15(4):312-319
PURPOSE: The purpose of this study was to determine the discriminant factors of attitude pattern toward sexual violence of college women. METHODS: A cross-sectional research design with non-probability samples was conducted. A total of 292 college women participated. The instruments were Attitude Pattern toward Sexual Violence, Self-Esteem Scale, Gender Role Scale, and Attitude toward Sexuality. Dependent variable is Attitude Pattern toward Sexual Violence, which is composed of two groups; cases either harmer blame or sufferer blame. Independent variables were self-esteem, attitude toward gender role, and attitude toward sexuality. Data were analyzed by SPSS WIN program and descriptive analysis, chi-square -test, and discriminant analysis. RESULTS: To assess the adequacy of classification, the overall hit ratio was 68.5%, and the significant predictor variable was attitude toward sexuality. CONCLUSION: Replication of the study needs to be considered to further enrich the specific knowledge base regarding attitude toward sexual violence among college women.
Female
;
Gender Identity
;
Humans
;
Knowledge Bases
;
Research Design
;
Sex Offenses
;
Sexual Behavior
;
Sexuality
2.The Study on Health Promoting Lifestyle of the Elderly Women.
Journal of Korean Academy of Nursing 2003;33(6):762-771
PURPOSE: This study was undertaken in order to determine factors affecting health promoting lifestyle of elderly women. METHOD: The subjects were 299 elderly community residing women over the age 65 living in 2 large cities. The instruments used for this study were a survey of general characteristics, health promoting lifestyle(47items), perceived health status(6 items), self-efficacy(17 items), and social support(18 items). The data was analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients, and Stepwise Multiple Regression. RESULT: The result of the study are as follows : The average item score for the health promoting lifestyle was 2.46, the highest score on the subscale was interpersonal support(M=2.83). A significant difference between age, education level, income, experience of smoking, alcohol, exercise, and health promoting lifestyle were found. Stepwise multiple regression analysis revealed that the most powerful predictor of health promoting lifestyle was social support(55%). CONCLUSION: Social support accounted for 54% of the variance in health promoting lifestyle in the elderly women. Therefore, health promoting programs that increase social support should be developed to promote a healthy lifestyle of the elderly women.
3.A Case of Lichen Planopilaris.
Mi Hae LIM ; Jong Hyuk PARK ; Seung Chul LEE ; Yong Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1997;35(1):139-143
Lichen planopilaris is believed to be a variant of lichen planus which is occasionally accompanied by classical lichen planus. A 68-year old male had asymptomatic skin colored or light violet colored papules and nodules on the occipital area followed by hair loss for 2 months. He had also violaceous pea to bean sized whitish scaly papules on the right lower extremity. Histopathological examination revealed the dilated follicles to be filled with horny material. There were also intense infiltrations of monocytes which were most prominent at the lower pole of the hair follicles on the scalp lesion. There was also hyperkeratosis, focal hypergranulosis and band-like infiltrations of lymphocytes at the dermo-epidermal junction on the lesion of the lower extremity. Direct immunofluorescence examination showed linear deposition of fibrin at the dermo-epidermal junction in the hair follicles. We had an opportunity to observe a man with lichen planopilaris who had loss of scalp hair which was accompanied by classical lichen planus on the lower extremity.
Aged
;
Fibrin
;
Fluorescent Antibody Technique, Direct
;
Hair
;
Hair Follicle
;
Humans
;
Lichen Planus
;
Lichens*
;
Lower Extremity
;
Lymphocytes
;
Male
;
Monocytes
;
Peas
;
Scalp
;
Skin
;
Viola
4.The comparison of feasibility and safety on fiberoptic guided intubation under conscious sedation with remifentanil and propofol.
Hae Mi LEE ; Jun SAKONG ; Dae Lim JEE
Korean Journal of Anesthesiology 2013;65(3):215-220
BACKGROUND: Oropharyngeal manipulation is problematic when patients have a gag reflex. Sedation can suppress gag reflex, but can cause serious airway problems. We compared remifentanil (Group R) and propofol (Group P) in terms of cooperation and loss of gag reflex, while drugs were administered incrementally using target controlled infusion (TCI). METHODS: Fifty seven patients who required awake fiberoptic intubation were randomized to Group R or Group P. After measurement of baseline gag trigger point index (GTPI), TCI was set to effect-site concentration (Ce) of 1 ng/ml (Group R) or 1 microg/ml (Group P), then titrated by 0.5 increment until GTPI score reached 0. The incidence of drop-out and decreased cooperation, Ramsay sedation scale (RSS) and Ce at loss of GR, and complications were assessed. RESULTS: Seven patients were dropped out in Group P due to deep sedation and disobedient behavior, but none in Group R (P = 0.015). Gag reflex suppressed as RSS increased in both groups (P < 0.001), however, the incidence of elimination of gag reflex clustered at RSS 2 in Group R (P < 0.001), whereas it was evenly distributed in Group P (P = 0.20). The incidence of patients who were spontaneously roused (gag reflex elimination at RSS 1 and 2) were higher in Group R than in Group P (P = 0.002). CONCLUSIONS: Deep sedation and impaired cooperation were observed only in Group P and spontaneously roused patients were higher in Group R, suggesting that remifentanil is more suitable for cooperative elimination of GR.
Conscious Sedation
;
Deep Sedation
;
Humans
;
Incidence
;
Intubation
;
Piperidines
;
Propofol
;
Reflex
;
Trigger Points
5.Clinical and Mycological Studies of Tinea Capitis in Chonnam Area (1986-1995).
Inn Ki CHUN ; Mi Hae LIM ; Seung Chul LEE ; Young Ho WON
Korean Journal of Medical Mycology 1996;1(1):83-89
BACKGROUND: The incidence, clinical characteristics and the causative fungi of tinea capitis vary according to geography and time. Although the clinical and mycological studies of tinea capitis have been widely reported in other provinces, the study in Chonnam province has not been estabilished yet. OBJECTIVE: The purpose of this study was to evaluate the prevalence, epidemiological and clinical features and the etiologic agents of tinea capitis in Chonnam area. METHODS: We performed clinical and mycological studies on 72 cases of tinea capitis which have been diagnosed by KOH examination or fungus culture or treatment trial among outpatients of Dermatologic Clinics of Chonnam University during 10 years. RESULTS AND CONCLUSION: The incidence of tinea capitis was 0.15% of outpatients and 2.6% of 2,889 superfical fungal infections. The ratio of male to female patients was 1 : 1.05. Most of patients(64 cases, 89%)were children under the age of 15, and 8 patients(11%) were the age of 15 to 80. The most common site of tinea capitis was parietal. Tinea faciale was combined in 14 cases(19.4%). In clinical features, the gray patch type was showed in 43.0%, pustular folliculitis-like in 25.0%, kerion celsi in 22.2%, seborrhic dermatitis-like lesion in 9.7% of patients with tinea capitis. Microsporum(M) canis was the most common causative fungi of tinea capitis(76.4%), with Ttichophyton(T) mentagrophytes(11.8%), T. rubrum(5.9%), T. verrucosum(2.0%), T. violaceum(2.0%), M. gypseum(2.0%) in the order of decreasing frequency.
Child
;
Female
;
Fungi
;
Geography
;
Humans
;
Incidence
;
Jeollanam-do*
;
Male
;
Outpatients
;
Prevalence
;
Rabeprazole
;
Tinea Capitis*
;
Tinea*
6.The association between serum IGF-1 and neonatal growth and disease in a NICU.
Jung Ok KIM ; Hae Ri LIM ; Heng Mi KIM
Korean Journal of Pediatrics 2009;52(2):176-180
PURPOSE: The objective of this study was to establish the serum IGF-1 level in newborn infants, and investigate its association with growth and diseases. METHODS: In a retrospective study, serum IGF-1 levels were measured for newborn infants admitted to NICU at Kyungpook University Hospital from March 2007 to July 2007. Birth data, disease history, and hospital course were obtained from medical records. RESULTS: Of 52 blood samples obtained at birth, serum IGF-l levels in 30 preterm infants (31.6+/-27.3 ng/mL) were lower than in 22 full-term infants (53.4+/-40.0 ng/mL; P<0.05). In sick full-term infants, serum IGF-1 levels (46.0+/-40.2 ng/mL) were lower than in healthy full-term infants (64.1+/-39.5 ng/mL; P<0.05). In preterm infants, there were no differences in IGF-1 levels between healthy (33.2+/-23.3 ng/mL) and sick infants (30.6+/-30.4 ng/mL); however, IGF-1 levels in both sick and healthy preterm infants were lower than in healthy full-term infants. Among infants admitted after 8 days of life, serum IGF-1 levels were higher in infants who gained weight (70.8+/-36.2 ng/mL) than in infants who lost weight (13.3+/-19.9 ng/mL; P<0.01); however IGF-1 levels showed no difference between gender or method of delivery. CONCLUSION: The study showed lower IGF-l levels in preterm infants than in full-term infants. Additionally, the IGF-l level in infants with weight loss was lower than in infants with weight gain. These results indicate that serum IGF-1 is associated with gestational age and postnatal growth.
Gestational Age
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Insulin-Like Growth Factor I
;
Medical Records
;
Parturition
;
Retrospective Studies
;
Weight Gain
;
Weight Loss
7.Polyvinyl Alcohol Embolization Adjuvant to Oily Chemoembolization in Advanced Hepatocellular Carcinoma with Arterioportal Shunts.
Yeo Ju KIM ; Hae Giu LEE ; Jeong Mi PARK ; Yeon Soo LIM ; Myung Hee CHUNG ; Mi Sook SUNG ; Won Jong YOO ; Hyun Wook LIM
Korean Journal of Radiology 2007;8(4):311-319
OBJECTIVE: To assess the feasibility and safety of polyvinyl alcohol (PVA) embolization adjuvant to transarterial oily chemoembolization (P-TACE) in advanced hepatocellular carcinoma (HCC) with arterioportal shunts (APS). MATERIALS AND METHODS: Nineteen patients who underwent PVA embolization for APS before a routine chemoembolization (TACE) procedure were retrospectively reviewed. 10 of these 19 patients underwent follow-up TACE or P-TACE after P-TACE (Group A), but nine patients underwent only initial P-TACE because of progression of HCC and/or underlying liver cirrhosis (Group B). Hepatic function tests, APS grades, and portal flow directions were evaluated before and after P-TACE sessions. Complications after procedures and survival days were also evaluated. RESULTS: In group A, APS grade was improved in eight patients and five of six patients with hepatofugal flow showed restored hepatopetal flow postoperatively. No immediate complication was developed in either group. Transient hepatic insufficiency developed in eight (42.1%) of 19 patients after P-TACE, and seven (87.5%) of these eight recovered within two weeks under conservative care. The mean and median survival time all study subjects was 280 days and 162 days. CONCLUSION: P-TACE is feasible and safe in advanced HCC patients with APS.
Adult
;
Aged
;
Aged, 80 and over
;
Antibiotics, Antineoplastic/administration & dosage
;
Arteriovenous Fistula/therapy
;
Carcinoma, Hepatocellular/mortality/*therapy
;
*Chemoembolization, Therapeutic
;
Contrast Media/administration & dosage
;
Feasibility Studies
;
Female
;
Humans
;
Iodized Oil/administration & dosage
;
Liver Circulation
;
Liver Neoplasms/mortality/*therapy
;
Male
;
Middle Aged
;
Mitomycin/administration & dosage
;
Polyvinyl Alcohol/*administration & dosage
;
Retrospective Studies
;
Treatment Outcome
8.Clarithromycin and Amoxicillin Susceptibility Testing of Helicobacter pylori by Disk Diffusion Method.
Heungsup SUNG ; Jung Oak KANG ; Mi Ae LEE ; Jongwook LEE ; Hae Kyung LEE ; Mi Kyung LEE ; Ji Hun LIM ; Mi Na KIM
Korean Journal of Clinical Microbiology 2009;12(1):30-36
BACKGROUND: CLSI provides a guideline only for a agar dilution method of testing clarithromycin susceptibility for Helicobacter pylori. This study was to evaluate a disk diffusion method for clarithromycin and amoxicillin. METHODS: One hundred and forty clinical isolates of H. pylori isolated from May 2005 to May 2007 were tested by the CLSI agar dilution method and a disk diffusion method using 2microgram (2CLR) and 15microgram (15CLR) clarithromycin disks and 2microgram (2AMX) and 10microgram (10AMX) amoxicillin disks. The interpretation criteria used for the disk diffusion method were established by linear regression and error rate-bounded method for disk diffusion zone of inhibition (DDZ) compared to MIC. RESULTS: Resistance and intermediate rates to clarithromycin were 21.4% and 1.4%, respectively. A number of isolates with MIC 0.5, 1, and 2 (microgram/mL) to amoxicillin were 7, 2, and 1, respectively. For 2CLR and 15CLR, the coefficients of determination (R2) between MIC and DDZ were 0.931 and 0.923 (P< 0.001), respectively, and the criteria for resistance/ susceptibility were 12/28 mm for 2CLR and 23/39 mm for 15CLR. For 2AMX and 10AMX, the R2 between MIC and DDZ were 0.478 and 0.421 (P< 0.001), respectively, and the criteria for resistance with breakpoint of 2microgram/mL were 21 mm for 2AMX and 32 mm for 10AMX. All isolates had DDZ<60 mm with 2CLR and 2AMX, but 61.4% and 75.7% of the isolates had DDZ<60 mm with 15CLR and 10AMX, respectively. CONCLUSION: Excellent correlation and agreement between MIC and DDZ were found for clarithromycin and amoxicillin. With 2microgram disks, the susceptibility breakpoints were 28 mm or less; thus, two disks could be tested in one plate.
Agar
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Amoxicillin
;
Clarithromycin
;
Diffusion
;
Helicobacter
;
Helicobacter pylori
;
Linear Models
9.Gene Expression of Endothelin-1 and Endothelin Receptor A on Monocrotaline-Induced Pulmonary Hypertension in Rats After Bosentan Treatment.
Kyoung Ah LIM ; Kwan Chang KIM ; Min Sun CHO ; Bo En LEE ; Hae Soon KIM ; Young Mi HONG
Korean Circulation Journal 2010;40(9):459-464
BACKGROUND AND OBJECTIVES: Endothelin (ET)-1, a potent endothelium-derived vasoconstrictor peptide, has a potential pathophysiologic role in pulmonary hypertension. Bosentan, a dual ET receptor (ET(A)/ET(B)) antagonist, is efficacious in treatment of pulmonary hypertension. The objectives of this study were to investigate the expression of ET-1 and ET receptor A (ERA) genes and to evaluate the effect of bosentan in monocrotaline (MCT)-induced pulmonary hypertension. MATERIALS AND METHODS: Four-week-old male Sprague-Dawley rats were treated as follows: control (n=36), subcutaneous (sc) injection of saline; MCT (n=36), sc injection of MCT (60 mg/kg); and bosentan (n=36), sc injection of MCT (60 mg/kg) plus 25 mg/kg/day bosentan orally. RESULTS: Serum ET-1 concentrations in the MCT group were higher than the control group on day 28 and 42. Quantitative analysis of peripheral pulmonary arteries revealed that the increase in medial wall thickness after MCT injection was significantly attenuated in the bosentan group on day 28 and 42. In addition, the increase in the number of intra-acinar muscular arteries after MCT injection was reduced by bosentan on day 14, 28 and 42. The levels of ET-1 and ERA gene expression were significantly increased in the MCT group compared with control group on day 5, and bosentan decreased the expression of ET-1 on day 5. CONCLUSION: ET-1 contributes to the progression of cardiopulmonary pathology in rats with MCT-induced pulmonary hypertension. Administration of bosentan reduced ET-1 gene expression in MCT-induced pulmonary hypertension in rats.
Animals
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Arteries
;
Endothelin-1
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Endothelins
;
Gene Expression
;
Humans
;
Hypertension, Pulmonary
;
Male
;
Monocrotaline
;
Pulmonary Artery
;
Rats
;
Rats, Sprague-Dawley
;
Receptors, Endothelin
;
Sulfonamides
10.Usefulness of interferon-γ release assay for the diagnosis of latent tuberculosis infection in young children.
Ki Wook YUN ; Young Kwang KIM ; Hae Ryun KIM ; Mi Kyung LEE ; In Seok LIM
Korean Journal of Pediatrics 2016;59(6):256-261
PURPOSE: Latent tuberculosis infection (LTBI) in young children may progress to severe active tuberculosis (TB) disease and serve as a reservoir for future transmission of TB disease. There are limited data on interferon-γ release assay (IGRA) performance in young children, which our research aims to address by investigating the usefulness of IGRA for the diagnosis of LTBI. METHODS: We performed a tuberculin skin test (TST) and IGRA on children who were younger than 18 years and were admitted to Chung-Ang University Hospital during May 2011-June 2015. Blood samples for IGRA were collected, processed, and interpreted according to manufacturer protocol. RESULTS: Among 149 children, 31 (20.8%) and 10 (6.7%) were diagnosed with LTBI and active pulmonary TB, respectively. In subjects lacking contact history with active TB patients, TST and IGRA results were positive in 41.4% (29 of 70) and 12.9% (9 of 70) subjects, respectively. The agreement (kappa) of TST and IGRA was 0.123. The control group, consisting of non-TB-infected subjects, showed no correlation between age and changes in interferon-γ concentration after nil antigen, TB-specific antigen, or mitogen stimulation in IGRAs (P=0.384, P=0.176, and P=0.077, respectively). In serial IGRAs, interferon-γ response to TB antigen increased in IGRA-positive LTBI subjects, but did not change considerably in initially IGRA-negative LTBI or control subjects. CONCLUSION: The lack of decrease in interferon-γ response in young children indicates that IGRA could be considered for this age group. Serial IGRA tests might accurately diagnose LTBI in children lacking contact history with active TB patients.
Child*
;
Diagnosis*
;
Humans
;
Interferon-gamma Release Tests
;
Latent Tuberculosis*
;
Skin Tests
;
Tuberculin
;
Tuberculosis