1.Induction of ovulation by intermittent subcutaneous injection of pure follicle-stimulating hormone in polycystic ovarian syndrome.
Dong Suk KIM ; Seung Joon SHIN ; Hye Young KIM ; Hae Yang LEE ; Joon Young PARK ; Young Sun PARK
Korean Journal of Fertility and Sterility 1993;20(2):125-130
No abstract available.
Female
;
Follicle Stimulating Hormone*
;
Injections, Subcutaneous*
;
Ovulation*
;
Polycystic Ovary Syndrome*
2.Rapid detection of mycobacterium tuberculosis in uncultured sputum samples by polymerase chain reaction.
Sung Joon KIM ; Jang Seong KIM ; Dahl Kyun OH ; Hae Ran MOON ; Hong Mo MOON
Journal of the Korean Society for Microbiology 1993;28(5):373-380
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction*
;
Sputum*
3.A Case of Desmoid Tumor
Dong Hae KIM ; Chung Nam KANG ; Sung Joon KIM ; Ki Hong CHOI
The Journal of the Korean Orthopaedic Association 1972;7(3):351-354
A case report of desmoid tumor(musculo-aponeurotic fibromatosis) arising from sternum and upper part of anterior sheath of rectus abdominis muscle in a one and half years old male child is reported. The patient's parent noticed a protruding hard mass on the lower end of sternal portion two weeks previous to surgery. The mass had dense, grayish white and glistering character invading the upper part of rectus abdominis muscle and cartilagenous portion of sternum including xyphoid process. Wide excision of mass including myo-fascial tissue of the rectus abdominal apponeurosis was performed. The excised mass was 4×4×2cm in size and the microscopic findings were typical desmoid tumor. The operative wound had partial skin necrosis due to poor circulation of skin because of the mass extended up to subcutaneous tissue and biopsy scar but eventually healed. There is no any signs of recurrence of tumor on 7 months postoperative follow up but may need more observation to define it.
Biopsy
;
Child
;
Cicatrix
;
Fibromatosis, Aggressive
;
Follow-Up Studies
;
Humans
;
Male
;
Necrosis
;
Parents
;
Rectus Abdominis
;
Recurrence
;
Skin
;
Sternum
;
Subcutaneous Tissue
;
Wounds and Injuries
4.Two Cases of Gastritis Cystica Superficialis without Previous Gastric Surgery.
Ji Hae KWON ; Ji Min KIM ; Su Jin LIM ; Joon CHOI ; Chul Tae KIM ; Kang Hee KIM ; Seung Keun PARK ; Hae Suk KIM ; Ju Ho KIM
Korean Journal of Gastrointestinal Endoscopy 2002;24(2):92-95
Gastritis cystica superficialis (GCS) is a rare lesion which is characterized by glandular hyperplasia with regeneration and degeneration in the mucosa and muscularis mucosa. Recently, GCS is revealed as precancerous lesion, but most report has been associated with those found at the site of a gastroenterostomy. So, we report two cases with GCS who had not previous gastric surgery. A 45-year-old woman visited for epigastric discomfort and another 4Q-year-old woman for epigastric pain. They had not undergone any gastric surgery. The gastroscopy discovered one polyp on anterior wall of greater curvature, upper body and another polyp in the center of the fold of greater curvature, lower body. We removed it by snare polypectomy and the histologic finding showed the character of GCS.
Female
;
Gastritis*
;
Gastroenterostomy
;
Gastroscopy
;
Humans
;
Hyperplasia
;
Middle Aged
;
Mucous Membrane
;
Polyps
;
Regeneration
;
SNARE Proteins
5.163 Cases of Decompression Sickness Among Korean Divers.
Korean Journal of Occupational and Environmental Medicine 1994;6(2):364-376
This study was performed to obtain an useful and basic information of the decompression sickness (DCS) among Korean divers. The medical records of 163 cases of Korean civilian diver, who were diagnosed as DES and received recompression therapy according to U.S. Navy Standard Recompression Treatment Table at Ocean & Underwater Medical Research & Training Center of ROK Navy, for 10 years from Jan. 1983 to Dec.1992. The total of 163 cases of DCS were catagorized into 2 groups as Type I DCS and Type II DGS group. The major results obtained were as follows: 1. 70.5% of total cases were classified as type II DCS, and the ratio of type I to type II DCS was 1'2.5 and the ratio of male to female of DCS cases was about 4:1. 2. About one third of cases occurred in May and June, and 38.7% of cases occurred at Chung-mu and Chin-hae in Kyung-nam province, the Southern Coast of Korean Peninsula. 3. Among the type II DGS group, 85.2% occured in diving for harpshell, and 85.2% with hookah diving gear. 4. There were no cases following the decompression procedure such as well known U.S. Navy's, and 86.7% of cases did not follow the any kinds of decompression procedure for preventing DCS and most of dives were conducted repetitively with 4.2 times on an average. 5. The mean depth between type I(27.3m) and type 11 DCS group(33.3m) showed significant difference statistically (p<0.01) , but both frequences of repetitive dives and bottom times between two groups were not statistically significant (p>0.05) . 6. The rate of symptoms appeared on surfacing and within 10 min. after surfacing of type I and type II DCS were 40.0% and 70.5%, respectively. And 80.9% of type I and 92.2% of type II DCS group were aware of dysbaric symptoms within the first hour after surfacing. 7. The most frequent symptoms and its percentages were "Both limb pain (37.6%) ",Joint pain(27.1%)., and "Scapular pain(22.9%)" in type I DCS group, and "Limb weakness or paralysis (68.7%)" , "Respiratory chokes(27.8%)" and "Bladder dysfunction(22.2%)"intypellDCSgroup. . 8. Among the type II DCS group, 54.8% attempted inwater recompression as a primary management, but 54.2% of type I DCS group did not take any kinds of therapeutic measure after onset of dysharic symptoms till commencing recompression treatment. 9. Recompression treatment was delayed 126.9 hours in type I and 89.7 hours in type II DCS group on an average, and the cases of DCS, who delayed more than two days till visiting the recompression facility, were occupied 52.1% in type I and 29.6% in type II DCS group. 10. Among the total cases, 32.6% were experienced one more of dysbaric symptoms in the past.
Decompression Sickness*
;
Decompression*
;
Diving
;
Extremities
;
Female
;
Humans
;
Male
;
Medical Records
;
Paralysis
6.Three Cases of Primary Adenosquamous Carcinoma of Stomach.
Joon Hyuk CHOI ; Mi Jin KIM ; Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE
Yeungnam University Journal of Medicine 1988;5(2):189-193
Adenosquamous carcinoma of stomach is a mixed glandular-epidermoid tumor where both components are neoplastic. Its incidence is extremely rare. The five theories on the origin of squamous components are 1) island of ectopic squamous epithelium in the gastric mucosa, 2) squamous metaplasia of gastric epithelium, 3) squamous differentiation in a preexisting adenocarcinoma, 4) endothelial cell differentiated toward squamous elements, and 5) totipotential undifferentiated cells of the gastric mucosa. We experienced three cases of adenosquamous carcinoma. Case 1 was a 71-year-old female patient; an ulcerative lesion was present in the pylorus, measuring 5 cm in diameter. Case 2 was a 57-year-old male patient; an ulcerative lesion is present in the pylorus, measuring 6 cm in diameter. Case 3 was a 58-year-old female patient; an ulcerative lesion was present in the body and fundus, measuring 10 cm in diameter. Microscopic examination revealed a mixed malignant squamous and adenomatous component.
Adenocarcinoma
;
Aged
;
Carcinoma, Adenosquamous*
;
Endothelial Cells
;
Epithelium
;
Female
;
Gastric Mucosa
;
Humans
;
Incidence
;
Male
;
Metaplasia
;
Middle Aged
;
Pylorus
;
Stomach*
;
Ulcer
7.A Case of Early Age Onset Hailey-Hailey Disease Treated with Surgical Operation.
Yong Sub OH ; Sung Yul LEE ; Hae Joon SONG ; Young Chul KYE ; Soo Nam KIM
Annals of Dermatology 1994;6(1):86-89
Hailey-Hailey disease is a rare hereditary dermatosis that begins in the 2nd or 3rd decade of life. The skin lesion is characterized by a localized, recurrent eruption of small vesicles on an erythematous base. It courses remissions and exacerbations. It seldom begins in early childhood, and main treatment modalities are conservative ones. We report a case of Hailey-Hailey disease that began on a 7-month old infant and improved by surgical treatment. In according to review of the previous reports, it is probably the earliest onset age and it is may be the first case which was treated with surgery in Korea.
Age of Onset
;
Humans
;
Infant
;
Korea
;
Pemphigus, Benign Familial*
;
Skin
;
Skin Diseases
8.Differential Expression of Glucose Transporter Gene in Mouse Early Embryos.
Hye won YOUM ; Hye kyung BYUN ; Gyun ji SONG ; Hae kwon KIM ; Ho Joon LEE
Korean Journal of Fertility and Sterility 1998;25(1):77-86
The uptake of glucose for metabolism and growth is essential to most animal cells and is mediated by glucose-transporter (GLUT) proteins. The aim of this study was to determine which class of glucose transporter molecules was responsible for uptake of glucose in the mouse early embryo and at which stage the corresponding genes were expressed. In addition, co-culture system with vero cell was used to investigate the effect of the system on GLUT expression. Two-cell stage embryos were collected from the superovulated ICR female and divided into 3 groups. As a control, embryos were cultured in 0.4% BSA-T6 medium which includes glucose. For the experimental groups, embryos were cultured in either co-culture system with vero cells or glucose-free 76 medium supplemented with 0.4% BSA and pyruvate as an energy substrate. 2-cell to blastocyst stage embryos in those groups were respectively collected into microtubes (50 embryos/tube). Total RNA was extracted and RT-PCR was performed. The products were analysed after staining ethidium bromide by 2% agarose gel electrophoresis. Blastocysts were collected from each group at 120hr after hCG injection. They were fixed in 2.5% glutaraldehyde, stained with hoechst, and mounted for observation. In control, GLUT1 was expressed from 4-cell to blastocyst. GLUT2 and GLUT3 were expressed in morula and blastocyst. GLUT4 was expressed in all stages. When embryos were cultured in glucose-free medium, no significant difference was shown in the expression of GLUTI1, 2 and 3, compared to control. However GLUT4 was not expressed until morular stage. When embryos were co-cultured with vero cell, there was no significant difference in the expression of GLUT1, 2, 3 and 4 compared to control. To determine cell growth of embryos, the average cell number of blastocyst was counted. The cell number of co-culture (93.8+/-3.1, n=35) is significantly higher than that of control and glucose-free group (76.6 +/- 3.8, n=35 and 68.2+/-4.3, n=30). This study shows that the GLUT genes are expressed differently according to embryo stage. GLUTs were detectable throughout mouse preimplantation development in control and co-culture groups. However, GLUT4 was not detected from 2- to 8-cell stage but detected from morula stage in glucose-free medium, suggested that GLUT genes are expressed autocrinally in the embryo regardless of the presence of glucose as an energy substrate. In addition, co-culture system can increase the cell count of blastocyst but not improve the expression of GLUT. In conclusion, expression of GLUT is dependent on embryo stage in preimplantation embryo development.
Animals
;
Blastocyst
;
Cell Count
;
Coculture Techniques
;
Electrophoresis, Agar Gel
;
Embryonic Development
;
Embryonic Structures*
;
Ethidium
;
Female
;
Glucose Transport Proteins, Facilitative*
;
Glucose*
;
Glutaral
;
Humans
;
Metabolism
;
Mice*
;
Morula
;
Pregnancy
;
Pyruvic Acid
;
RNA
;
Vero Cells
9.Adjustment of urinary mercury in health risk assessment of mercury.
Eunil LEE ; Hye Kyung PARK ; Hae Joon KIM
Journal of Korean Medical Science 1996;11(4):319-325
The determination of adjustment method of urinary mercury in spot urine is one of the important issues in assessing the health risks of mercury workers. But there have been debates about whether creatinine or other forms of correction for urinary concentration are better in reducing the variation of urinary mercury. We evaluated four adjustment methods-specific gravity, creatinine, log creatinine and excretion rate-by correlation between values adjusted by the four methods and individual exposure levels which were the geometric mean of daily air mercury level for 2 or 5 days, and mercury concentrations in 24 hour urine were also investigated to compare the results of spot urine. The correlation between values of spot urine and mercury exposure level was over 0.8 in all adjustment methods for workers who worked over 1 year. All four adjustment methods for urinary mercury were found to be similar in assessing the exposure, log creatinine and excretion rate method however were not practical to use due to lack of reference values, and variable standard values of specific gravity. And the creatinine adjusted values were more sensitive in low mercury exposure level. We therefore recommend the creatinine adjustment method for adjustment of urinary mercury.
Adult
;
Air Pollutants, Occupational/*urine
;
Female
;
Human
;
Male
;
Mercury/*urine
;
Middle Age
;
Risk Assessment
;
Time Factors
10.A case of kidney transplantation in primary oxalosis.
Sang Joon KIM ; Seung Ki MIN ; Hae Il JUNG ; Yong CHON
The Journal of the Korean Society for Transplantation 1993;7(1):237-243
No abstract available.
Hyperoxaluria, Primary*
;
Kidney Transplantation*
;
Kidney*