Necrotizing lymphadenitis was first recognised as a self-limiting lymphadenitis by Japanese workers in 1972. It is a distinct clinicopathologic entity, but can be mistaken as malignant lymphoma. We have studied clinicopathologic features in 15 cases of necrotizing lymphadenitis. This disease occurs predominantly in young adult. Male-female ratio is 2 : 1. The commonest presentation is lateral cervical lymphadenopathy. Pain, tenderness, and fever can be seen. Biopsy of the lymph nodes from all patients demonstrates the characteristic histologic features : multifocal, relatively circumscribed nodules in the cortex and/or paracortex, consisting of a mixture of activated large lymphoid cells, histiocytes and Small lymphocytes. Numerous karyorrhetic debris are present. Neutrophils and plasma cells are strikingly absent.
Asian Continental Ancestry Group ; Biopsy ; Fever ; Histiocytes ; Humans ; Lymph Nodes ; Lymphadenitis* ; Lymphatic Diseases ; Lymphocytes ; Lymphoma ; Neutrophils ; Plasma Cells ; Young Adult

Although causative factors are not completely defined, carcinogenesis of colorectal cancer is attributed to multiple genetic alterations. The abnormal expressions of oncogenes are regarded to be responsible for the production of malignant phenotype, subsequent invasion and metastasis. From 63 surgically resectable colorectal adenocarcinoma patients, expression of oncogenes in colorectal cancer tissue was evaluated with immunohistochemical staining methods using monoclonal antibodies to products of the oncogenes. To evaluate the possibility of oncogenes as a prognostic factor, we studied the relationship between the expression of oncogenes and the clinicopathologic findings which are well known prognostic factors. Rates of expression in colorectal cancer tissue were 27% for c-myc, 74.6% for c-Ha-ras and 77.8% for c-erbB-2 oncogenes. The positive rate of c-erbB-2 oncogene was higher in the well differentiated group than in the poorly differentiated group. The rates of expression of c-myc and c-Ha-ras oncogenes were significantly correlated each other. Expression of these oncogenes in colorectal cancer were not correlated with the pathologic stage, location of cancer, DNA ploidy pattern and histologic differentiation except between c-erbB-2 and histologic differentiation. In conclusion, there seems to be a possibility that c-erbB-2 could be used as a prognostic factor of colorectal cancer. However, further and more intensive study seems to be required.
Adenocarcinoma ; Antibodies, Monoclonal ; Carcinogenesis ; Colorectal Neoplasms* ; DNA ; Humans ; Neoplasm Metastasis ; Oncogenes* ; Phenotype ; Ploidies

This is case report of true class III malocclusion with macroglossia is corrected by glossectomy in 13 years female patient. After orthodontic treatment, the patient is bound to glossectomy because the corrected condition is relapsed to the previous condition due to relatively enlarged tongue compared with the original dental arch. By the interpretation of the cephalogram and model analysis, it is approved that the growth pattern and direction are normal range and mandible is located anterioly to the cranium. The results are follows: 1. We could treat the true Cl III malocclusion. 2. We could prevent the relapse of the treated condition by the surgical intervention, such as partial glossectomy. 3. Sensory, speech, swallowing and so other functions after the operation have been with in normal limit without any serious complications or seguellae.
Deglutition ; Dental Arch ; Female ; Glossectomy ; Humans ; Macroglossia* ; Malocclusion* ; Mandible ; Recurrence ; Reference Values ; Skull ; Tongue

We tried to treat 16 patients with superficial transitional cell carcinoma of the bladder with prophylactic and therapeutic intravesical chemotherapy. The 2 drugs used were adriamycin and thio-tepa and checked for efficacy by repeated cystoscopy with at least 3 months` interval. The clinical data and results of both groups are presented and the importance of intravesical treatment with minimal toxicity is discussed with a brief review of the literatures.
Carcinoma, Transitional Cell ; Cystoscopy ; Doxorubicin ; Drug Therapy* ; Humans ; Thiotepa ; Urinary Bladder Neoplasms* ; Urinary Bladder*

PURPOSE: The purpose of this study was to identify nicotine dependence, smoking-related attitude, and subjective norms across the stages of change for smoking cessation among adult smokers in a rural area. METHOD: The subjects were 276 current smokers (male=243, female=33). There were 3 stages of change for smoking cessation: pre-contemplation, contemplation, and preparation stage. Data was collected by an interview or self-reporting from February 12th to March 5th 2004, and analyzed with frequency, percentage, chi-square-test, Fisher's exact probability test, ANOVA, and Scheffe test using the SPSS-PC program. RESULT: According to the stages of change, 114(41.3%) current smokers were in pre-contemplation, 110(39.9%) in contemplation, and 52(18.8%) in the preparation stage. There was a higher percentage of males than females (chi-square=8.99, p=.011) in the preparation stage. The mean score of the smoking-related attitude (F=7.43, p=.001) and subjective norm(F=27.41, p=.001) were both lowest in the pre-contemplation stage and increased positively during the stages of change for smoking cessation. CONCLUSION: Based on these findings, the authors recommend that community-based smoking cessation programs should be developed by considering the intention or motives of current smokers and should be initiated in the preparation stage and primarily for male groups.
Adult ; Aged ; Aged, 80 and over ; Attitude to Health ; Female ; Humans ; Interviews as Topic ; Male ; Middle Aged ; Motivation ; Nicotine ; Questionnaires ; Rural Population ; Smoking Cessation/*psychology ; Tobacco Use Disorder/*psychology

PURPOSE: The purpose of this study was to investigate the effects of a community-based group smoking cessation program among adult smokers in a rural community. METHOD: The study design was quasi-experimental with a pre and posttest. A total of 55 adult smokers participated in the study. They were evaluated 1, 3, and 6 months after the program to identify the long-term effectiveness of the program. The program consisted of a total of 5 sessions provided twice a week. To test the effectiveness of the program, urine creatinine, expired air carbon monoxide, nicotine dependence, and smoking-related knowledge were used as dependent variables. Data was analyzed with the SPSS 10.0 program with a t-test, paired t-test, and Scheffe test. RESULT: Urine creatinine, expired air carbon monoxide, and nicotine dependence were significantly decreased after the program. Also, the rates of continuous abstinence were 81.8% at posttest, 65.5% at 1 month, 54.5% at 3 months, and 54.5% at 6 months follow-up. CONCLUSION: This community-based group smoking cessation program implemented by a nurse and smoking cessation counselors was effective for quitting smoking and decreasing urine creatinine and nicotine dependence. Therefore, this smoking cessation program could be recommended to induce smoking cessation as health promotion management in the rural community.
Adult ; Aged ; Breath Tests ; Carbon Monoxide/analysis ; Cotinine/urine ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Patient Education as Topic ; Rural Population ; Smoking/prevention & control/*psychology ; Smoking Cessation/*methods ; Tobacco Use Disorder/*therapy ; Treatment Outcome

The prognostic significance of vascular (blood and lymphatic vessels) invasion was evaluated in a retrospective review of 27 patients with upper urinary tract transitional cell carcinoma from January 1985 to December 1993, who underwent a nephroureterectomy with bladder cuff resection. Vascular invasion was found in 10 patients (37%). The incidence of vascular invasion was well correlated with tumor grade and stage. The incidence of postoperative metastases was significantly higher in the patients with (70%) than without (17.6%) vascular invasion (p<0.05). The survival rate of the patients with vascular invasion was significantly lower than in those without vascular invasion (p<0.01). In multivariate Cox`s regressional analysis the prognostic value of vascular invasion was independent of tumor grade and stage. These results indicate that vascular invasion should predict a more unfavorable outcome in patients with upper urinary tract transitional cell carcinoma as an independent morphological indicator.
Carcinoma, Transitional Cell* ; Humans ; Incidence ; Lymphatic Vessels* ; Neoplasm Metastasis ; Prognosis ; Retrospective Studies ; Survival Rate ; Urinary Bladder ; Urinary Tract*

PURPOSE: The purpose of this study was to identify the effects of a school-based obesity control program based on behavior modification and self-efficacy for obese elementary school children. The program was composed of strategies to modify diet and exercise habits and to increase self-efficacy. METHOD: The subjects were 57 obese children (experimental group = 28, control group = 29) whose Rohler index was 150 and over. The program was implemented once a week for 12 weeks from September 16 to December 12, 2003. The data was analyzed by Fisher's exact probability, chi2-test, t-test, and Wilcoxon Rank Sum test. RESULT: The Rohler index, fat mass and lean body mass of the experimental group positively changed after the intervention more than those of the control group, but there was a significant difference in the Rohler index only (t=2.06, p=.045). In addition, obesity stress significantly decreased (z=-2.86, p=.047) and dietary self-efficacy significantly increased (t=2.35, p=.023) in the experimental group than those of the control group. CONCLUSION: This study supports that a school-based obesity control program based on behavior modification and self-efficacy can be effective in decreasing obesity stress and increasing dietary self-efficacy. Parents, school nurses and the other support groups should be encouraged to participate from the planning stage of the program to be effective in weight control of obese elementary school children. Also school-based program should be implemented as an essential course in the curriculum, not as an elective.
Weight Loss ; *Self Efficacy ; *School Health Services ; Obesity/*therapy ; Male ; Humans ; Female ; Diet, Reducing ; Child ; *Behavior Therapy

The mechanism of erectile dysfunction associated with psychotherapeutic medication is not well defined. To determine whether psychotherapeutic drugs have a direct effect on penile cavernosal smooth muscle, the activity of 4 drugs from 4 major classes of psychotherapeutic agents, chlorpromazine, thioridazine, haloperidol and amitriptyline, was examined in vitro on isolated rabbit corpus cavernosum. Strips of corpus cavernosum were mounted in organ baths for isometric tension studies. The effect of the drugs on resting tension, their relaxant effect on norepinephrine (NE) precontracted tissue, and their effect on electrical field stimulated (EFS) relaxation of NE precontracted tissue were determined. Incubation with any of the drugs did not affect resting tension compared to a control. All drugs produced a dose-dependent relaxation in NE precontracted tissue which were significantly greater than the water treated control (p<0.0001). None of the drugs inhibited EFS relaxation. These result show that these classes of drugs do not affect the basal tone of the corpus cavernosum. All have intrinsic relaxant properties and none interfere with neurally stimulated relaxation. This study suggests that drugs from these 4 major classes of psychotherapeutic agents do not adversely affect penile cavernosal smooth muscle relaxation at the level of the penis and its associated neural elements. It may be inferred that reports of impotence in patients treated with these classes of drugs more likely reflect a central or primary psychopathologic process rather than a local corpus cavernosum effect.
Amitriptyline ; Baths ; Chlorpromazine ; Erectile Dysfunction ; Haloperidol ; Humans ; Male ; Muscle, Smooth ; Norepinephrine ; Penis ; Relaxation ; Thioridazine ; Water

No abstract available.
Cystadenoma, Mucinous* ; Mucins* ; Pancreas*