The exact etiology and pathogenesis of myopia are not known yet, although various studies of the development of myopia in experimental animals have been made. Authors attemtped whether rabbits developed axial myopia by fusing their lids at birth in one eye, or not. The monocular vision was deprived by suture of upper and lower lids in 12 rabbits which were 5 day-old. The other eye was unsutured as the control. Ten months later, we assessed refractive error, corneal curvature, axial length, and intraocular pressure and enucleation was done. We observed the histologic change of sclera with light microscope. The eyes with lid suture were more myopic(-3.35 +/- 0.99D) than the controlled eyes(-0.21 +/- 0.46D) (p<0.01). The corneal curvature and intraocular pressure were not significantly different between two groups. The axial lengths of the sutured eves were increased(21.27 +/- 1.70mm) in comparison with those of the controlled(17.39 +/- 1.83mm)(p<0.01). We conclude the difference in axial length was caused by the elongation of the posterior segment of eyeball. since lens thickness, depth of anterior chamber, and corneal curvature were identical in both groups. These were correlated with histologic change that showed thinner posterior parts of sclera of the sutured eyes than those of the controlled eyes. The results of this study demonstrate that monocular lid fusion in rabbits produced an expenmental axial myopia.
Animals ; Anterior Chamber ; Eyelids* ; Intraocular Pressure ; Myopia* ; Parturition ; Rabbits* ; Refractive Errors ; Sclera ; Sutures* ; Vision, Monocular

Multicystic ovary was first described by Silver in 1958 as a rare case feature of acquired primary hypothyroidism. In 1980, Lindsay reported four girls with hypothyroidism associated with multicystic ovary diagnosed by pelvic ultrasonography. The mechanism of ovarian cyst formation and pseudoprecocious puberty in severe hypothyroidism in childhood are unknown. Increased ovarian sensitivity to GnRH and increased TSH level which acts on FSH receptor is one of the mechanism explained. We report a case of a girl with primary hypothyroidism presented with pseudoprecocious puberty and giant follicular ovarian cyst with torsion.
Adolescent ; Female ; Gonadotropin-Releasing Hormone ; Humans ; Hypothyroidism* ; Ovarian Cysts* ; Ovary ; Puberty ; Receptors, FSH ; Silver ; Ultrasonography

No abstract available.
Animals ; Dietary Fats* ; Rats*

PURPOSE: This study was done to identify and compare factors associated with intention to receive Human Papillomavirus (HPV) vaccine between male and female undergraduate students. METHODS: In the fall of 2010, 479 students responded to self-administered questionnaires about their intention to receive HPV vaccine, HPV knowledges, HPV related involvements and optimistic bias, subject's characteristics including opinion about HPV vaccine. Mann-Whitney U test, uni-variate and multi-variate logistic regression were used for data analysis with SPSS/WIN. RESULTS: Intention to receive vaccine were 22.0% of men and 25.0% of women. There were significantly different in HPV knowledge (Z=-2.74, p=.006), optimistic bias (Z=-4.60, p<.001), vaccine is necessary for women (Z=-4,30, p<.001), vaccine is necessary for men (Z=-4.37, p<.001), vaccine is necessary if only symptom exist (Z=-4.52, p<.001), but there were not different in intention to receive vaccine, involvement between men and women. Concern about vaccine safety (OR=3.19, 95% CI 1.63~6.23) was determinant of intention to receive HPV vaccine for men. CONCLUSION: This study showed gender differences in HPV knowledge, HPV related optimistic bias and opinion about HPV vaccine, which would be assessed and well managed in tailored HPV education for enhancing HPV vaccine acceptance.
Bias (Epidemiology) ; Female ; Humans ; Intention ; Logistic Models ; Male ; Papillomavirus Vaccines ; Surveys and Questionnaires ; Sexually Transmitted Diseases ; Statistics as Topic

PURPOSE: This study was done to examine mothers' acceptance and its influencing factors in daughters' human papillomavirus (HPV) vaccination to prevent cervical cancer. METHODS: From July 20 to August 31, 2010, 220 mothers of unmarried daughters responded to self-administered questionnaires about their acceptance of HPV vaccination for their daughters and the optimal age for HPV vaccination. Descriptive statistics, univariate logistic and multiple logistic regression were used for data analysis with SPSS/WIN 12.0. RESULTS: Mothers indicating their willingness to pay for their daughters to receive HPV vaccination accounted for 61.8%, and willingness with health insurance coverage, 84.5%. Mean optimal age for HPV vaccination was 19.78+/-3.96) years. With self-payment the factor influencing mothers willingness was necessity of HPV vaccination (OR=30.45, 95% CI=10.33~89.15). With health insurance coverage, income (OR=3.02, 95% CI: 1.19~7.62), necessity of HPV vaccination (OR=15.05, 95% CI=4.15~54.64), concern about HPV vaccine safety (OR=2.99, 95% CI=1.15~7.76), and experience of Pap test (OR=3.16, 95% CI=1.24~8.05) were factors influencing mothers willingness. Other influencing factors were optimal age for HPV vaccination, knowing about HPV (OR=7.66, 95% CI=2.19~26.82), and age of youngest daughter (OR=3.95, 95% CI=1.34~11.68). CONCLUSION: Financial support is anticipated for low income families in a primary approach to increase HPV vaccination. And focusing on earlier age and concerns about vaccination are necessary to gain mothers' acceptance.
Financial Support ; Humans ; Insurance, Health ; Logistic Models ; Mothers ; Nuclear Family ; Papillomavirus Vaccines ; Questionnaires ; Single Person ; Statistics as Topic ; Uterine Cervical Neoplasms ; Vaccination

PURPOSE: This study was conducted to identify the association of dietary intake levels with ante-natal depression among pregnant women. METHODS: Secondary data analysis was done using Can Pro software (version 3.0) to evaluate the diet intake levels with 24 hour recall diary method with 130 pregnant women visiting a general hospital. Statistical analysis included descriptive statistics, t-test, Mann-Whitney U test and adjusted logistic regression using the SPSS/WIN program. RESULTS: Whole dietary intake levels of pregnant women were insufficient according to Recommended Nutrient Intake (RI) with the except of phosphorus intake. There were significant differences in RI by gestation period and high risk pregnancies. Non-depressed women showed more intake in niacin (z=1.33, p=.018) and zinc (t=3.99, p=.048) than depressed women did. Niacin was a significant determinant of ante-natal depression (Exp (B)=5.88, p=.47, 95% CI [1.02~23.83]). CONCLUSION: Dietary intake assessment would be necessary during pregnancies for the screening of ante-natal depression. For ante-natal depression care, a tailored dietary intervention should be applied for women with insufficient nutrient intake.
Depression ; Diet ; Female ; Hospitals, General ; Humans ; Logistic Models ; Mass Screening ; Niacin ; Phosphorus ; Pregnancy ; Pregnant Women ; Statistics as Topic ; Statistics, Nonparametric ; Zinc

PURPOSE: The purpose of this study was to differentiate between women with three perimenstrual symptom severity patterns : premenstrual syndrome (PMS), premenstrual magnification (PMM), and low symptom (LS), and to explore the related dietary factors to premenstrual symptoms. METHOD: Women were asked to keep a diary record of perimenstrual symptoms and food intake for 50 days. RESULT: Symptom patterns were defined for 26 among 38 women ; Eight (21.1%) demonstrated a PMS pattern, three (7.9%) demonstrated a PMM pattern, and fifteen (39.5%) exhibited a LS pattern. There were significant differences in symptom scores during the premenstrual phase (x2=19.30, p=.000), menstrual phase (x2=13.32, p=.001), and post menstrual phase (x2=9.93, p=.007) for three groups. Protein, vit E, vit C, niacin, folic acid, and phosphorus in the premenstrual phase, and energy, and vit B6 in the menstrual period were significantly different between the three groups. Among dietary compositions, amino acids, lipids, fatty acids, saturated fatty acids, natrium, vit B6, niacin, and vit E were negatively related to PMS symptoms. CONCLUSION: Pattern of perimenstrual symptoms should be differentiated for individualized PMS management. As a more efficient diet assessment for PMS women, randomized nutritional analysis during the 3 phases of the menstrual cycle should be done and a replication study is necessary with a larger sample.
Amino Acids ; Diet ; Eating ; Fatty Acids ; Female ; Folic Acid ; Humans ; Menstrual Cycle ; Niacin ; Phosphorus ; Premenstrual Syndrome*

This study was done to determine the factors influencing smoking-cessation behavior in female university students. a total of 534 students participated in this cross sectional study by answering a questionnaire. The data collection was done between September 1 and October 31, 1997. The measurement tools used in this study were the self help change process scale(Cronbach's alpha=.9930 : developed by Oh&Kim, 1996) for smoking-cessation behaviors, the self efficacy scale(Cronbach's alpha=.8250 : developed by Sherer et al, 1982), the sex role acceptance scale(KR-20=.7757 : developed by Kim, 1991) and the social support scale(Cronbach's alpha=.9172 : developed by Park, 1985). The summarized results are follows : 1. The mean scores for smoking-cessation behaviors in smokers(N=150) was 91.72 that was considered a middle score compared to the total possible score of measurement tool(150.0). The mean score for smoking-cessation behaviors by smoking-cessation step showed significant different between the groups(F=11.71, p= .000). 2. The group with no experience in smoking(N=332) showed a high general self efficacy score(t=5.24, p= .000), and more openness to sex role acceptance(t=-2.15, p= .032) compared to the group with smoking experience(N=202). 3. General self efficacy, sex role acceptance, and social support were not different significantly between the groups according to the steps in smoking-cessation. 4. Significant factors influencing smoking-cessation behavior(total, sub concepts) were religion, sex role acceptance, social support, smoking duration, smoking attitude, time of smoking onset, amount of smoking, drinking, and perception of health status. 5. Smoking-cessation behaviors which explained 11% of the variance were smoking attitude, and smoking duration. In conclusion, this study identified factors influencing smoking-cessation behavior. Thereby it will help in the development of smoking-cessation ration other determinants of smoking cessation behaviors, evaluation of intervention efficiency, and comparative study by gender characteristics are needed.
Surveys and Questionnaires ; Drinking ; Female* ; Gender Identity ; Humans ; Self Efficacy ; Smoke ; Smoking ; Smoking Cessation ; Social Distance ; Women's Health

This study was done to determine the factors influencing smoking-cessation behavior in female university students. a total of 534 students participated in this cross sectional study by answering a questionnaire. The data collection was done between September 1 and October 31, 1997. The measurement tools used in this study were the self help change process scale(Cronbach's alpha=.9930 : developed by Oh&Kim, 1996) for smoking-cessation behaviors, the self efficacy scale(Cronbach's alpha=.8250 : developed by Sherer et al, 1982), the sex role acceptance scale(KR-20=.7757 : developed by Kim, 1991) and the social support scale(Cronbach's alpha=.9172 : developed by Park, 1985). The summarized results are follows : 1. The mean scores for smoking-cessation behaviors in smokers(N=150) was 91.72 that was considered a middle score compared to the total possible score of measurement tool(150.0). The mean score for smoking-cessation behaviors by smoking-cessation step showed significant different between the groups(F=11.71, p= .000). 2. The group with no experience in smoking(N=332) showed a high general self efficacy score(t=5.24, p= .000), and more openness to sex role acceptance(t=-2.15, p= .032) compared to the group with smoking experience(N=202). 3. General self efficacy, sex role acceptance, and social support were not different significantly between the groups according to the steps in smoking-cessation. 4. Significant factors influencing smoking-cessation behavior(total, sub concepts) were religion, sex role acceptance, social support, smoking duration, smoking attitude, time of smoking onset, amount of smoking, drinking, and perception of health status. 5. Smoking-cessation behaviors which explained 11% of the variance were smoking attitude, and smoking duration. In conclusion, this study identified factors influencing smoking-cessation behavior. Thereby it will help in the development of smoking-cessation ration other determinants of smoking cessation behaviors, evaluation of intervention efficiency, and comparative study by gender characteristics are needed.
Surveys and Questionnaires ; Drinking ; Female* ; Gender Identity ; Humans ; Self Efficacy ; Smoke ; Smoking ; Smoking Cessation ; Social Distance ; Women's Health

It was assumed that the maternal identity in primigravida is one of the most attribute of the motherhood, that is not biological but cognitive phenomena, appears active process as intelligent human being. The purposes of this study were that the identification the cognitive structure and the influencing factors of the maternal identity in primigravida. Theoretical framework in this study, maternal identity in primigravida was constructed as a cognitive output, has the cognitive structure of cognitive output, has cognitive structure of cognitive-perceptual factor, cognitive-behavioral factor, and cognitive-emotional factor. Influencing factors of maternal identity was constructed as a cognitive input, which were pregnancy related perceptions(pregnancy intention, minor discomfort, value of motherhood), interpersonal relationship(relationship with mother, relationship with husband, relationship with social network), preparation to motherhood(maternal knowledge, antenatal, self care), and biological factor(gestation period). This study was to descriptive correlational research design, was done from the 3rd January to the 15th March 1996, and the research subjects were selected conveniently 226 the primigravida during the gestation period, data collection method was self reported questionnaire cross-sectionally. Descriptive data analysis was done SAS PC+, testing the hypothetical model was done by covariance structural analysis using LISREL 8.03 program. The result of the hypothesis testing, the value of motherhood(gamma=.650, T=4.26) the maternal knowledge(gamma=.137, T=2.030), the gestation period(gamma=.113, T-2.621), showed significant causal effect on the maternal identity in primigravida. In conclusion, the maternal identity in primigravida had interrelated cognitive structure consist of perceptual, behavior, and emotional factors. Significant causal factors influencing the maternal identity were value identified. It seems to contribute toward the understanding the characteristics of the maternal identity as a cognitive domains that has been regarded highly abstract concept, so has not been validated empirically.
Surveys and Questionnaires ; Humans ; Intention ; Mothers ; Pregnancy ; Research Design ; Research Subjects ; Self Report ; Spouses ; Statistics as Topic