1.Erythrocyte 2,3-DPG and ATP Concentration in Intraoperative Salvaged Blood and CPD Stored Blood.
Sung Tae KIM ; Myung Hae PARK ; Hae Kyung KIM
Korean Journal of Anesthesiology 1993;26(3):506-511
The purpose of this study is to compare the quality of intraoperative salvaged blood with that of Citrate Phosphate Dextrose(CPD) stored blood in 32 patients having cardiac surgery involving cardiopulmonary bypass. 20 patients in the control group received one week cild CPD stored blood and 12 patients received autologous intraoperative salvaged blood which prepared and processed with the Hemonetics Cell Saver Plus autotransfusion device. 1) Salvaged blood had a higher hemoglobin concentration(l7.6 vs 13.1 g/dl, P<0.005), a higher 2.3-diphosphoglycerate concentration(3.1 vs 0.6 mmol/L, P<0.005), higher pH(7.6 vs 6.8, P<0.005) than CPD stored blood group. Salvaged blood had a lower ATP concentration was(47.7 vs 67.7 pmol/dl, P<0.005) than stored blood group. 2) Platelet count was l3.4 X 10(9)/L and WBC count was 5.09 X 10(9)/L in salvaged blood. 3) Salvaged blood volume was 1411+/-487.9 ml(range 580 to 2325 ml). Intraoperative salvaged blood had a superior oxygen carrying and delivery capacity, but modification of washing is required to lessen the platelet and white blood cell count in the salvaged blood.
2,3-Diphosphoglycerate*
;
Adenosine Triphosphate*
;
Blood Platelets
;
Blood Transfusion, Autologous
;
Blood Volume
;
Cardiopulmonary Bypass
;
Citric Acid
;
Erythrocytes*
;
Humans
;
Leukocyte Count
;
Oxygen
;
Platelet Count
;
Thoracic Surgery
2.Cephalometric analysis of mandibular growth in rabbits.
Hae Wook LEE ; Sung Tack KWON ; Chin Whan KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(2):216-221
No abstract available.
Rabbits*
3.A study on the hepatitis B markers of pregnant women and their infants in yeoju area.
Hae Joong KIM ; Pyoung Sham KU ; Sung Bong HONG
Korean Journal of Perinatology 1993;4(1):23-28
No abstract available.
Female
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Infant*
;
Pregnant Women*
4.Bactericidal Effect of Disinfectant Tego-51(R).
Jong Sung SUK ; Hae Shim CHOI ; Eui Chong KIM
Korean Journal of Nosocomial Infection Control 1997;2(1):55-59
BACKGROUND: Disinfection is essential for the prevention of hospital infoction. Tego-51, one of the amphoteric surfactants based on the dodecyl-di( aminoethyl)-glycine, has been considered as an effctive disinfectant having a broad specturn of antimicrobial activity. We evaluated the disinfective activity of Tego-51 against several clinical isolates of bacteria and yeasts including Helicobacter pyiori. METHODS: Twenty three strains of vacteria including H. pylori, and a strain of yeast were exposed to the various concentrations (0.05%, 0.01%, 0.005%) of Tego-51 for the various periods (0.5, 1, 2, 4, 8, 16min). After the exposure to Tego-51 disinfectant, 0.01 mL of mixture of microorfanisms and Tego-51 was inoculated into brain-heart infusion broth, into Sabouraud dextrose agar. or Wilkins-Chalgren agar with 10% sheep blood, and incubated at 37 degrees C for 48 hours or in the Campy Pouch microaerophilic system. RESULTS: Most strains were killed within 30 seconds after an exposure to 0.01% of Tego-51, but Proteus mirabilis was eradicated after two minutes of exposure. At the concentration of 0.005 % concentration. P. mirabilis and Bacillus subtilis were killed after eight minutes od exposure. H. pylori was killed with 0.005% Tego-51within 30 seconds. Conslusions: This study showed that Tego-51disinfectant was effective for the disinfection of commonly isolated bacteria and yeast from hospital. It may be recommended that Tego-51 should be used at concentration greater than 0.1% for the effective disinfection of skin, instruments and hospital floors.
Agar
;
Bacillus subtilis
;
Bacteria
;
Cross Infection
;
Disinfection
;
Glucose
;
Helicobacter
;
Mirabilis
;
Proteus mirabilis
;
Sheep
;
Skin
;
Surface-Active Agents
;
Yeasts
5.A Case of Cutaneous Ossification occurring in Pseudohypoparathyroidism.
Hyohyun AHN ; Ki Sung KIM ; Il Hwan KIM ; Hae Jun SONG ; Hae Won CHEON ; Joo Won LEE ; Chil Hwan OH
Annals of Dermatology 1999;11(4):263-266
In Albright's hereditary osteodystrophy (AHO) including the syndromes of pseudohypoparathyroidism (PHP) and pseudopseudohypoparathyroidism (PPHP), multiple areas of intracutaneous ossification are often encountered. The characteristic features are short stature, round face, short neck, obesity, cutaneous ossifications, and various skeletal anomalies including short metacarpal and metatarsal bones, curve of radius, and brachydactyly. The patient was a 10-month-old male infant. He presented slightly depressed erythematous hard plaques on the left upper chest and left thigh. We had taken biopsies from both skin lesions, confirming cutaneous ossification or bone formation. He also had the characteristic features of AHO. He had a history of admission due to patent ductus arteriosus and atrial septal defect. The laboratory results showed slightly decreased calcium, increased phosphorus and PTH levels. The patient received no specific corrective measures because his calcium and phosphorus levels were not far from normal values until newly developed similar skin lesions appeared.
Biopsy
;
Brachydactyly
;
Calcium
;
Ductus Arteriosus, Patent
;
Heart Septal Defects, Atrial
;
Humans
;
Infant
;
Male
;
Metatarsal Bones
;
Neck
;
Obesity
;
Osteogenesis
;
Phosphorus
;
Pseudohypoparathyroidism*
;
Pseudopseudohypoparathyroidism
;
Radius
;
Reference Values
;
Skin
;
Thigh
;
Thorax
7.A Case of Klippel-Trenaunay-Weber Syndrome Diagnosed by Antenatal Ultrasonography.
Yong Won PARK ; Jae Wook KIM ; Sung Hoon KIM ; Jae Sung CHO ; Yeon Hae LEE ; Sung Sik HAN ; Hae Kyung KWON
Korean Journal of Obstetrics and Gynecology 2000;43(6):1092-1095
Klippel-Trenaunay-Weber syndrome is a rare, sporadically occuring disorder characterized by hemihypertrophy (unilateral limb hypertrophy), varicose veins, hemangiomata and occasionally arteriovenous malformation. With the development of ultrasonography, this syndrome can be detected by antenatal sonography. We report a case of Klippel-Trenaunay-Weber syndrome that demonstrates huge mass with increased blood flow on left thigh detected by ultrasonography.
Arteriovenous Malformations
;
Extremities
;
Klippel-Trenaunay-Weber Syndrome*
;
Thigh
;
Ultrasonography*
;
Varicose Veins
8.Studies on the lectin binding patterns of the oviduct luminal epithelium and oocytes in mouse.
Myung Chan GYE ; Sung Rye KIM ; Hae Kwon KIM ; Moon Kyoo KIM
Korean Journal of Fertility and Sterility 1993;20(3):267-276
No abstract available.
Animals
;
Epithelium*
;
Mice*
;
Oocytes*
;
Oviducts*
;
Phenobarbital*
9.Coexistence of Porokeratosis of Mibelli and Disseminated Superficial Actinic Porokeratosis(DSAP).
Joo Won KIM ; Ki Sung KIM ; Chong Hyeok KIM ; Chil Hwan OH ; Hae Jun SONG
Annals of Dermatology 2000;12(2):144-147
There have been several reports of more than one type of porokeratosis occurring in the same family or the same individual. We hope to support the view of different phenotypic expressions of a common genetic aberration by describing an additional case of porokeratosis of Mibelli on the perianal area and DSAP on the face, forearms occurring in a 45-year-old man.
Actins*
;
Forearm
;
Hope
;
Humans
;
Middle Aged
;
Porokeratosis*
10.The Pulmonary Hemodynamic Effects of Nitric Oxide Inhalation on Hypoxic Pulmonary Vasoconstriction.
Hae Jeong JEONG ; Seong Kee KIM ; Chung Su KIM ; Jeon Jin LEE ; Sung Deok KIM
Korean Journal of Anesthesiology 1997;33(5):811-821
BACKGROUND: Nitric Oxide (NO) has been discovered to be an important endothelium-derived relaxing factor. The exogenous inhaled NO may diffuse from the alveoli to pulmonary vascular smooth muscle and produce pulmonary vasodilation, but any NO that diffuses into blood will be inactivated before it can produce systemic effects. To examine the effects of NO on pulmonary and systemic hemodynamics, NO was inhaled by experimental dogs in an attempt to reduce the increase in pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR) induced by hypoxia in dogs. METHODS: Eight mongrel dogs were studied while inhaling 1)50% O2 (baseline), 2)12% O2 in N2 (hypoxia), 3)followed by the same hypoxic gas mixture of O2 and N2 containing 20, 40 and 80 ppm of NO, respectively. RESULTS: Breathing at FIO2 0.12 nearly doubled the pulmonary vascular resistance from 173 56dyn sec cm-5 to 407 139dyn sec cm-5 and significantly increased the mean pulmonary artery pressure from 16 3mmHg to 22 4mmHg. After adding 20~80 ppm NO to the inspired gas while maintaining the FIO2 at 0.12, the mean pulmonary artery pressure decreased (p<0.05) to the level when breathing oxygen at FIO2 0.5 while the PaO2 and PaCO2 were unchanged. The pulmonary vascular resistance decreased significantly and the right ventricular stroke work index returned to a level similar to breathing at FIO2 0.5 by addition of NO into the breathing circuit. Pulmonary hypertension resumed within 3~5 minutes of ceasing NO inhalation. In none of our studies did inhaling NO produce systemic hypotension and elevate methemoglobin levels. CONCLUSIONS: Inhalation of 20~80 ppm NO selectively induced pulmonary vasodilation and reversed hypoxic pulmonary vasoconstriction without causing systemic vasodilation and bronchodilation. Methemoglobin and NO2 were within normal limit during the study.
Animals
;
Anoxia
;
Dogs
;
Endothelium-Dependent Relaxing Factors
;
Hemodynamics*
;
Hypertension, Pulmonary
;
Hypotension
;
Inhalation*
;
Methemoglobin
;
Muscle, Smooth, Vascular
;
Nitric Oxide*
;
Oxygen
;
Pulmonary Artery
;
Respiration
;
Stroke
;
Vascular Resistance
;
Vasoconstriction*
;
Vasodilation