1.Monocular Axial Myopia following Neonatal Eyelid Suture in The Rabbits.
Hae Won KIM ; Hae Jung PAIK ; In Sook MIN
Journal of the Korean Ophthalmological Society 1995;36(9):1574-1581
The exact etiology and pathogenesis of myopia are not known yet, although various studies of the development of myopia in experimental animals have been made. Authors attemtped whether rabbits developed axial myopia by fusing their lids at birth in one eye, or not. The monocular vision was deprived by suture of upper and lower lids in 12 rabbits which were 5 day-old. The other eye was unsutured as the control. Ten months later, we assessed refractive error, corneal curvature, axial length, and intraocular pressure and enucleation was done. We observed the histologic change of sclera with light microscope. The eyes with lid suture were more myopic(-3.35 +/- 0.99D) than the controlled eyes(-0.21 +/- 0.46D) (p<0.01). The corneal curvature and intraocular pressure were not significantly different between two groups. The axial lengths of the sutured eves were increased(21.27 +/- 1.70mm) in comparison with those of the controlled(17.39 +/- 1.83mm)(p<0.01). We conclude the difference in axial length was caused by the elongation of the posterior segment of eyeball. since lens thickness, depth of anterior chamber, and corneal curvature were identical in both groups. These were correlated with histologic change that showed thinner posterior parts of sclera of the sutured eyes than those of the controlled eyes. The results of this study demonstrate that monocular lid fusion in rabbits produced an expenmental axial myopia.
Animals
;
Anterior Chamber
;
Eyelids*
;
Intraocular Pressure
;
Myopia*
;
Parturition
;
Rabbits*
;
Refractive Errors
;
Sclera
;
Sutures*
;
Vision, Monocular
2.A Case of Agnogenic Myeloid Metaplasia.
Min Sook UM ; Jo Sam KOO ; Jae Sun PARK ; Sook Ja PARK ; Hae Kyung JANG
Journal of the Korean Pediatric Society 1988;31(11):1486-1493
No abstract available.
Primary Myelofibrosis*
3.Changes of Plasma Homovanillic Acid in Neuroleptic Responsive and Non-responsive Schizophrenics.
Hae Sook SUH ; Chul Eung KIM ; Min Hee KANG
Journal of Korean Neuropsychiatric Association 1999;38(1):156-165
OBJECTIVES: Changes in plasma homovanillic acid(HVA) were investigated in neuroleptic responsive and non-responsive schizophrenics in order to delineate parameters of dopamine regulation, which may underlie differences in neuroleptic responsivity. METHOD: Twenty newly admitted acute schizophrenic patients were treated with haloperidol for 6 weeks. HVA was sampled at baseline, 3 days after initial neuroleptic dose, and after 1, 2, 3, 4, 6 weeks of treatment. Nine patients were classified as responders in this prospective haloperidol treatment trial. They had a score of change in the BPRS total scores of 25% or greater. Eleven patients were classified as nonresponders, based on a score of changes in the BPRS total scores of less than 25%. RESULTS: 1) The age of onset in respnder was older than nonresponder. 2) There were no significant changes in plasma HVA levels in total patients during 6 weeks haloperidol treatment period, but the nonreponders had a robust decrease in HVA level from baseline to 3 days and one week after haloperidol treatment in successive comparison. 3) There were no significant correlations between plasma HVA level and total scores of BPRS. CONCLUSIONS:This study suggested that neuroleptic non-responsive schizophrenics had a different plasma HVA concentration during haloperidol treatment but could not provide support to the idea that change in plasma HVA in response to neuroleptics can predict eventual clinical response to treatment. Further study is required in order to better characterize the changes in dopamine turnover in subgroups of schizophrenics.
Age of Onset
;
Antipsychotic Agents
;
Dopamine
;
Haloperidol
;
Homovanillic Acid*
;
Humans
;
Plasma*
;
Prospective Studies
;
Schizophrenia
4.The Value of Computerized Tompgraphy in Diagnosis and Early Surgery of the Orbital Blow Out Fractuers.
Ji Yeong YI ; Hae Jung PAIK ; In Sook MIN
Journal of the Korean Ophthalmological Society 1995;36(11):1854-1863
We compared the diagnostic accuracy of the simple x-ray with that of the computed tomography, and analyzed the surgical results according to the timing of operation in 52 patients with suspected orbital blowout fractures who complained diplopia after midfacial trauma. Of all the cases, 40 orbital fractures were confirmed with CT and forced duction test and the remaining 12 patients were thought to have transient functional impairment because the clinical signs were resolved with time. CT detected all the 40 actual fractures, so the dignostic accuracy(100%) was higher than that of the simple x-ray(75%) which detected 30 fractures of the 40 actual fractures(p=0.001). We operated 19 patients who have persistent diplopia, enophthalmos of more than 2 mm, and large fracture defect, and there was significant improvement of symptoms and signs in patients on whom operations were performed within 2 weeks after trauma rather than after 2 weeks.
Diagnosis*
;
Diplopia
;
Enophthalmos
;
Humans
;
Orbit*
;
Orbital Fractures
5.The Effects of Thoracic Epidural Anesthesia on Pulmonary Shunt during One Lung Anesthesia.
Hun CHO ; Yoon Sook LEE ; Nan Sook KIM ; Hye Won LEE ; Hae Ja LIM ; Sung Ho CHANG ; Suk Min YOON
Korean Journal of Anesthesiology 1999;37(5):793-798
BACKGROUND: Hypoxemia during one lung ventilation (OLV) for thoracotomy in patients in the lateral position remains a clinical problem. And thoracic epidural anesthesia (TEA) during one lung ventilation recently has been combined with general anesthesia in our clinical practice for thoracic surgery. Then the effects of TEA combined with general anesthesia on PaO2 remains controversial. The aim of this study to investigate whether thoracic epidural anesthesia (TEA) affect PaO2 and pulmonary shunt during one lung anesthesia. METHODS: Fifteen patients undergoing lobectomy with one lung ventilation were examined. Each group was injected normal saline (control group, n = 7) or 1% lidocaine (TEA group, n = 8) 8 ml through thoracic epidural catheter after induction. We compared pulmonary shunt fraction (Qs/Qt) after OLV 30, 60 minutes and after two lung ventilation (TLV). RESULTS: We found the significant increases of intrapulmonary shunt fraction (%) in the TEA group compared to control group at each event, OLV30, 60 and TLV. And significant increase of intrapulmonary shunt was found after one lung ventilation in the both groups. CONCLUSIONS: These results suggest that TEA may influence hypoxic pulmonary vasoconstriction (HPV) by blockade of sympathetic activity during OLV.
Anesthesia*
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Anesthesia, Epidural*
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Anesthesia, General
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Anoxia
;
Catheters
;
Humans
;
Lidocaine
;
Lung*
;
One-Lung Ventilation
;
Tea
;
Thoracic Surgery
;
Thoracotomy
;
Vasoconstriction
;
Ventilation
6.Metabolic syndrome in the overweight and obese adolescents and the impact of obesity on the cardiovascular system.
Young Mi HONG ; Young Whan SONG ; Hae Soon KIM ; Hae Sook PARK ; Jung Hae MIN ; Jo Won JUNG ; Nam Su KIM ; Chung Il NOH
Korean Journal of Pediatrics 2009;52(10):1109-1118
PURPOSE: Metabolic syndrome (MS), characterized by obesity and insulin resistance, elicits risk factors such as hyperlipidemia, hypertension, and glucose intolerance with additive effects on atherosclerosis, leading to cardiovascular diseases. The purposes of this study were to evaluate the prevalence of MS among overweight and obese adolescents and to investigate the impact of obesity on the cardiovascular system. METHODS: tal cholesterol, triglyceride, low-density-lipoprotein (LDL)-cholesterol, high-density-lipoprotein (HDL)-cholesterol, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and high-sensitive C-reactive protein (hs-CRP) were measured in the patients with a BMI of >85 percentile. Brachial-ankle pulse wave velocity (BaPWV) and ankle brachial index were measured using Vascular Profiler (VP)-1000. RESULTS: MS was confirmed in 19.5% of the overweight and obese adolescents and 50.8% of the obese adolescents. The systolic and diastolic blood pressure, height, weight, fat mass, %fat, BMI, obesity index, and waist circumference were higher in the overweight and obese adolescents with MS. Moreover, the triglyceride, AST, ALT, and hs-CRP levels were higher, whereas HDL-cholesterol level was significantly lower in this group. The overweight and obese adolescents with MS showed shorter diastolic and systolic times, higher heart rate and BaPWV, and longer E-wave deceleration time by echocardiography. CONCLUSION: Overweight and obese adolescents showed characteristic MS features such as hypertension and hyperlipidemia. Thus, obese adolescents predisposed to MS should be provided early treatment for obesity.
Adolescent
;
Alanine Transaminase
;
Ankle Brachial Index
;
Aspartate Aminotransferases
;
Atherosclerosis
;
Blood Pressure
;
C-Reactive Protein
;
Cardiovascular Diseases
;
Cardiovascular System
;
Cholesterol
;
Deceleration
;
Glucose Intolerance
;
Heart Diseases
;
Heart Rate
;
Humans
;
Hyperlipidemias
;
Hypertension
;
Insulin Resistance
;
Obesity
;
Overweight
;
Prevalence
;
Pulse Wave Analysis
;
Risk Factors
;
Waist Circumference
7.Analysis of Research Papers Published in the Journal of Korean Academy of Nursing.
Yeon Ok SUH ; Jeong Sook PARK ; Jin Hyang YANG ; Hae Won KIM ; Min Hyun SUK ; Hyun Sook SHIN ; Hee Jung JANG ; Myun Sook JUNG ; Myung Sill CHUNG
Journal of Korean Academy of Nursing 2007;37(6):1013-1019
PURPOSE: This study was to determine the current trend of nursing research as exploring both quantitative and qualitative methodologies, and to provide the explicit direction to improve the quality of published papers. METHODS: Total of 366 articles published between 2004 and 2006 was reviewed using the criteria of analysis. RESULTS: There was more number of quantitative studies than qualitative studies. More studies were conducted with subjects who had health problems, and studies that targeted women and elderly population have been significantly increased. In quantitative methodology, utilization of experimental and quasi-experimental designs has been increased, however descriptive study was dominant as yet. In qualitative methodology, studies using grounded theory and phenomenology were frequently published. It was noted that theoretical framework and rational for sample size were rarely presented in quantitative study. Philosophical position and the process of preparation for study, which guided the research, were not clearly described in qualitative study. CONCLUSION: The findings of this review suggest that published studies have been improved and diversified, however, detailed and clear evaluation tool that assesses study process and method should be developed as a way to further improve the quality of published papers.
Bibliometrics
;
Humans
;
Korea
;
Nursing Methodology Research/*standards
;
*Periodicals as Topic
;
Qualitative Research
8.Accuracy of References in Eight Nursing Journals in Korea.
Min Hyun SUK ; Hee Jung JANG ; Jeong Sook PARK ; Hae Won KIM ; Yeon Ok SUH ; Hyun Sook SHIN ; Jin Hyang YANG ; Myun Sook JUNG ; Myung Sill CHUNG
Journal of Korean Academy of Nursing 2008;38(1):180-185
PURPOSE: This study was to investigate the reference accuracy in major nursing journals in Korea. METHODS: The references in articles from eight nursing journals from 2006 were compared with PubMed for authors, year, title, journal, volume, and page accuracy. Four hundred sixty-six references were reviewed. Errors were classified as major or minor and categorized by bibliographic headings (author, title, journal, year, volume and page). RESULTS: Of the 466 references, 223(47.9%) had citation errors. The reference error rates ranged from 28.6% to 58.7%. Most errors occurred in the author element (37.9%), followed by title (20.9%), journal (19.0%), page (13.9%), volume (5.9%), and year (2.4%). CONCLUSION: This study identified a considerable error rate in the references of nursing journals. Inaccuracy of references is a reflection on scholarly work of authors and journals. Authors and Editorial committees are responsible for the accuracy of references.
*Bibliography as Topic
;
Humans
;
Korea
;
*Nursing
;
Peer Review, Research
;
Periodicals as Topic
9.Radiologic Localization and Lengths of Umbilical Artery Catheter to Major Aortic Branches Determined by Ultrasonography in Neonates.
Byoung Min CHOI ; Hae Won CHEON ; Kee Hwan YOO ; Young Sook HONG ; Joo Won LEE ; Soon Kyum KIM
Journal of the Korean Society of Neonatology 1999;6(2):225-233
PURPOSE: Incorrect positioning of umbilical artery catheter (UAC) results in an increased incidence of complications and erroneous pressure measurements. We radiologically localized major aortic branches and calculated the length of catheter from umbilicus to celiac artery, renal artery and aortic bifurcation for optimal positioning of UAC. To determine the neonatal body measurement that best predicts optimal UAC lengths, we studied three commonly used parameters-birth weight (BW), total body length (TBL) and shoulder-umbilicus length (SUL). METHODS: Fifty one high type of UAC were routinely identified by sonographic scanning from the epigastrium in longitudinal projection and 42 low type of UAC from the flank in coronal projection. The distances from the catheter tip to the celiac artery, the renal artery and to the aortic bifurcation were measured by electronic calipers and were compared with the length of the catheter from umbilicus to the tip on the chest anteroposterior radiograph. RESULTS: The celiac arteries originated from T10-T12, renal arteries Ll-L2, and aortic bifurcations L3-L5. There was positive correlation between BW, TBL or SUL and the length of catheter to the celiac artery (r2=0.476, 0.749 or 0.753), to the renal artery (r2= 0.785, 0.847 or 0.720), and to the aortic bifurcation (r2=0.714, 0.809 or 0.747). CONCLUSION: Although any one of the three parameters can be used clinically, we prefer the TBL and SUL parameters for its reliability and usefulness in emergency settings. The use of a new distribution plot of origins of major branches and regression equations for calculation of the lengths may help deciding the optimal position of UAC.
Catheters*
;
Celiac Artery
;
Emergencies
;
Humans
;
Incidence
;
Infant, Newborn*
;
Renal Artery
;
Thorax
;
Ultrasonography*
;
Umbilical Arteries*
;
Umbilicus
10.Posterior Thoracic Spinal Cord Artery Infarction.
Sang Don HAN ; Ha Young SHIN ; Sook Keun SONG ; Hae Sun KO ; Seung Min KIM ; Il Nam SUNWOO
Journal of the Korean Neurological Association 2005;23(5):718-720
No abstract available.
Arteries*
;
Infarction*
;
Spinal Cord Vascular Diseases
;
Spinal Cord*