A case of congenital self-healing histiocytosis was studied with S-100 antibody and electron microscopy. Many tumor cells were positive for S-100 protein and a few contained Birbeck´s grandles and dense bodies. A pathlogic fracture was first noticed on the seventh day. The lesions involuted spontaneously by the end of a weeks
Histiocytosis* ; Microscopy, Electron ; S100 Proteins

BACKGROUND: At least 30 per cent of diabetics, which is said to comprise over 3% of general population in Korea, have one or more cutaneous complications during the course of the disease. These skin changes may be the consequences of microangiopathy, arteriosclerosis, direct metabolic disturbances and/or the sequelae of chronic therapy. OBJECTIVE: We tried to observe certain cutaneous and nail changes in diabetics and to relate them with systemic complications, blood sugar level and duration of diabetes. METHODS: During the period of 12 months from March, 1992 to February, 1993, a total of 1858 outpatients diagnosed as diabetes mellitus at Eulji General Hospital were examined. RESULTS: The cutaneous manifestations are observed in 79.5% of diabetics examined and cutaneous infections are the most prevalent(52.3%). Pruritus(p<0.01), anogenital pruritus(p<0.01), peripheral dedema(p<0.05) are more common in females and infections, shin spots, finger pebbles(p<0.01) are more common in males. Systemic complications are observed in 50.7% and the cutaneous manifestations are observed more frequently in patients with systemic complications(p<0.05). Shin spots, diabetic foot, peripneral edema diabetic bullosis are observed frequently associated with systemic microangiopathic complications such as retinopathy, nephropathy and neuropathy(p<0.01). There is a significant correlation between blood sugar level and fungal infections and anogenital pruritus(p<0.01). The frequencies of shin spots, diabetic foot and diabetic bullosis increase with the length of time diabetes has been present. Nail changes are observed in 39.6% of diabetics and onychomycosis is the most frequent(34.5%). CONCLUSION: It is suggested that cutaneous shgns especially fungal infections in diabetics are on the increase in Korea. A variety of skin conditions are encountered with diabetes mellitus and the dermatologist may be able to make a significant contribution in the control of diabetes mellitus by identifying skin signs and conditions as diabetic complications.
Arteriosclerosis ; Blood Glucose ; Diabetes Complications ; Diabetes Mellitus* ; Diabetic Foot ; Edema ; Female ; Fingers ; Hospitals, General ; Humans ; Korea ; Male ; Onychomycosis ; Outpatients ; Skin

The purpose of this study was to identity the level of burden and quality of life of the subjects. The subjects of this study were 68 mothers of nephrotic syndrome patients who children hospitalized in 2 Pediatric wards of University Hospital in Seoul. The data were collected through a questionnaires and the period of the data collection was from August 1st to September 30th ,1998. The instruments for this study were Burden Measurement Instrument developed by Montgomery et. al (1985) and Quality of life scale designed by Ro, Yoo JA (1988). The statistical analysis was used by SPSS, t-test, ANOVA and Pearson correlation coefficient. The results of were as follows : 1. The level of burden showed a mean score 54.47 and the level quality of life, a mean score 140.20. 2. The level of burden differed according to s religion, pt's purpose of admission and perceived patient's condition by mothers. 3. The level of quality of life differed according to perceived pt's condition by mothers. 4. There was a negative correlation between burden and quality of life(r=-3.97, p<.001).
Child* ; Data Collection ; Humans ; Mothers* ; Nephrotic Syndrome* ; Quality of Life* ; Seoul ; Child Health ; Surveys and Questionnaires

Lymphangioleiomyomatosis(LAM) is a rare disease of women of child-bearing age in which there is progressive hyperplasia of atypical smooth mucle along lymphatics in the lung, and/or axial lymphatics in the thorax and abdomen, resulting in honeycombing of lung. Interestingly there has been a speculation that it represents a forme furste or incomplete expression of tuberous sclerosis complex. This is based on the observation that patients with tuberous sclerosis can manifest pulmonary lesions indistinguishable from LAM. We report a case of LAM occuring in a 39-year-old female, who complained of recurrent pneumothorax, chest pain and shortness of breath. Three years ago, the patient had right nephrectomy under the diagnosis of ruptured angiomyolipoma. A X-ray film of the chest showed honeycombing with a diffusely reticulonodular pattern and cyst-like spaces. She had a characteristic facial appearance of adenoma sebaceum, which her father and uncle had. Microscopically, the lung showed a marked smooth muscle proliferation around the slit-like lymphatic spaces and also some respiratory bronchioles.
Female ; Humans ; Adenoma

This is a nonequivalent control group pretest- posttest design in quasi experimental basis to assess how the thermal head and feet support influences on early stage weight gain in premature neonates. The clients were selected among the premature infants with the weight under 2000gms and with the gestational period under 37 weeks, admitted over 15 days in K university hospital, Seoul. The control group of 29 were selected from January 1998 to August 1998, who were without head and feet thermal support, and the experimental group of 30 were selected from September 1998 to May 1999, who were with the two thermal interventions. The results of the study follow, 1.The experimental group with thermal interventions showed more weight gain than the control group without thermal interventions, which was statistically significant between the two groups. 2.The physiological weight loss after birth showed less in the experimental group than in the control group. 3.The recovery of the birth weight after the physiologic weight loss showed no statistical difference between the experimental group and the control group. Consequently, the thermal head and feet supportive nursing intervention could be applied as a nursing intervention program to help the premature neonates' development. With the results above we should like to suggest the following: 1) A continuous application in the practice of our thermal supportive intervention for the premature neonates, a development of the content through evaluation, and a comparision of the results through a long time study. 2) A neccessity of deveopment of various study and cross comparision. 3) A neccessity of multi-angular study on the premature infants' characteristics influencing the thermal therapy and the study of the individual differences of the clients.
Birth Weight ; Body Weight ; Foot* ; Head* ; Humans ; Individuality ; Infant, Newborn* ; Infant, Premature ; Nursing ; Parturition ; Seoul ; Time and Motion Studies ; Weight Gain* ; Weight Loss ; Child Health

Recently the high-density porous polyethylene[Medpor(r)]has been used as a new orbital implant for the reconstruction after enucleation or evisceration to reduce the implant exposure and migration, and to increase the prosthesis motility. We performed 16 cases of Medpor(r) orbital implantation combined with enucleation, evisceration or secondary orbital implantation between November 1997 and December 1998. Then, we investigated the postoperative complication, prosthesis motility, fibrovascular ingrowth pattern into the implant and MCP[Medpor(r) Coupling Post]insertion to increase the prosthesis motility for the average of 10 months [range, 6 to 18 months]. We performed a total of 16 cases of implantation :10 cases after evisceration, 5 cases after enucleation and 1 case as secondary implantation. There were 3 cases of conjunctival dehiscence, 1 case of retrobulbar hemorrhage and 1 case of superior sulcus deformity. There were no implant exposure, migration or severe inflammation. Postoperative prosthesis motility was found in 13 cases as good, 2 cases as fair and 1 case as poor. After enucleation or evisceration, Medpor(r) orbital implantation showed no significant difference from the previous porous orbital implants in postoper ative complication, prosthesis motility and fibrovascular ingrowth into the implant. It appears to be a good orbital implant because of the lower material cost, convenience in the operative procedure and other advantages. But long-term follow-up may be necessary for the detection of clinical change, the complication of MCP insertion and for the evaluation of the fibrovascular ingrowth pattern after Medpor(r) implantation.
Congenital Abnormalities ; Follow-Up Studies ; Inflammation ; Orbit* ; Orbital Implants* ; Postoperative Complications ; Prostheses and Implants ; Retrobulbar Hemorrhage ; Surgical Procedures, Operative

The purpose of this study was to identify the effect of the supportive nursing intervention program on Burden and Quality of Life in Mothers of Children with Nephrotic Sybdrome. The data were collected from a group of 67 mothers of nephrotic syndrome patients(34 in the intervention group, 33 in the control group) from July 1, 1998 to Dec, 30, 1988, Measurements were burden and quality of life from both groups at pre and post intervention. The supportive nursing educational program consists of individual lectures and discussion at the individual level. Listed are the summarized result: 1. The intervention group had a lower level of burden (p<0.05) than the control group intervention. 2. The level of quality of life was not significant during the intervention. According to this study a developed supportive musing intervention program is effective for reduction of the burden. For future research, it is necessary that experiments concerning quality of life in mothers of children with nephrotic syndrome, be conducted.
Alprostadil ; Child* ; Education, Nursing* ; Humans ; Lectures ; Mothers* ; Nephrotic Syndrome ; Nursing* ; Quality of Life*

A 34-year-old Korean woman who had been taking warfarin for 14 years after mitral valve replacement became pregnant. She was heparinized betwen 6 and14 weeks of gestation and was then restarted on oral anticoagulants. At 32 weeks of gestation, fetal ultrasonography revealed overt enlargement of the left lateral ventricles. There was an echogenic mass in the right hemisphere with mild ventricular enlargement. An elective repeat cesarean section was performed. Three days later, the neonate underwent a Burr-hole procedure, from which bloody fluid was drained and the intracranial hemorrhage was confirmed. We must keep in mind the severe adverse fetal outcomes associated with warfarin-induced fetal intracranial hemorrhage during pregnancy. Despite its therapeutic advantages, regular fetal monitoring, ultrasonography, and management of prothrombin time are needed.
Adult ; Anticoagulants ; Cesarean Section, Repeat ; Female ; Fetal Monitoring ; Heparin ; Humans ; Infant, Newborn ; Intracranial Hemorrhages ; Lateral Ventricles ; Mitral Valve ; Pregnancy ; Prothrombin Time ; Ultrasonography, Prenatal ; Warfarin

OBJECTIVE: The purpose of this study was to evaluate the clinical characteristics and the management of the unusual ectopic pregnancies. METHODS: Sixty one patients who were diagnosed as unusual ectopic pregnancies in the Department of Obstetrics and Gynecology, Inje University Ilsan Paik Hospital from December 1999 to June 2006, were retrospectively analyzed. The chief complaints, past histories, time of diagnosis, serum beta-hCG concentrations and method of the management were reviewed. RESULTS: During the designated study period, the incidence rate of the ectopic pregnancy was 9.5% of the all deliveries and that of the unusual ectopic pregnancy was 18.8% of the total ectopic pregnancies. In twenty two cases, implantation sites were not found out exactly by sonography at initial diagnosis. Theses ectopic pregnancies were cornual pregnancy (3 cases), ovarian pregnancy (6 cases), abdominal pregnancy (3 cases), and unclassified unusual ectopic pregnancy (10 cases). Unusual ectopic pregnancies which were diagnosed before six weeks of gestation were eleven cases. These unusual ectopic pregnancies were 6 cases in cervical pregnancy, 1 case in abdominal pregnancy, and 4 cases in unclassified unusual ectopic pregnancy. Initial mean serum beta-hCG concentration was the highest in cornual pregnancies and the lowest in abdominal pregnancies. MTX (methotrexate) was administered in seven cases, operation was done in forty six cases, and expectant management was done in nine cases. All initial treatment was successful except one case with cornual pregnancy, which was MTX administered with alternative regimen. CONCLUSIONS: In our study the diagnostic accuracy of the unusual ectopic pregnancy was 63.9% and the successful treatment was done in 98.3% of them. There were significant statistical differences between the serum beta-hCG concentrations and the kinds of unusual ectopic pregnancies (p<0.001).
Female ; Gynecology ; Humans ; Incidence ; Obstetrics ; Pregnancy ; Pregnancy, Abdominal ; Pregnancy, Ectopic ; Retrospective Studies

PURPOSE: To evaluate the factors affecting the outcome of occlusion treatment for amblyopia. METHODS: We analyzed 80 amblyopic patients who had been followed up more than 6 months after occlusion treatment according to the age at start of treatment, initial corrected visual acuity of amblyopic eye, difference of corrected visual acuity between two eyes, type of amblyopia, type of occlusion and patient compliance. RESULTS: Mean age was 6.01+/-1.76 (3~12) years at start of treatment and mean treatment period was 4.51+/-3.40 (2~12) months. Success of treatment was defined as optotype acuity of 0.5 or better in the amblyopic eye and less than one-line difference between the two eyes. The success rate was 74% (59/80) and the time for initial visual improvement was 1.57+/-0.77 months. The age at start of treatment did not correlate with the success rate and period of treatment. But the less the difference of corrected visual acuity between the two eyes and the greater the initial corrected visual acuity, the higher the success rate and the shorter the period of treatment. And the better the compliance, the higher the success rate. Aniosmetropic amblyopia and strabismic amblyopia had the higher success rate and shorter treatment of period than mixed type amblyopia. In anisometropic amblypia, hyperopic and astigmatic type had the shorter period of treatment than myopic type. In the group of the smaller difference in refractive error, the success rate was high and period of treatment was short. In strabismic amblyopia, exotropia had the higher success rate and shorter peroid of treatment than esotropia. But the prism diopter did not correlate with the success rate and period of treatment. CONCLUSIONS: For occlusion treatment of amblyopia, we must consider many factorsto establish the treatment plan and to predict the outcome of treatment.
Amblyopia* ; Compliance ; Esotropia ; Exotropia ; Humans ; Patient Compliance ; Refractive Errors ; Visual Acuity