No abstract available.

Comflicting results have been reported on whether ketamine potentiates the neuromuscular effect of succinylcholine or other non-depolarizing agents. Notably, there has been no reported clinical evatuation of the influence of ketamine upon the neuromuscular action of vecuronium a new muscle relaxant. The present study was undertaken to estimate the influence of ketamine upon the neuromuscular action of vecuronium with a single bolus injection of ED95. Forty-five ASA class l or ll surgical patients were divided into three groups: l, ll and lll and were given thiopental sodium(5mg/kg), ketamine 3mg/kg and ketamine 5mg/kg as induction agents, respectively. The duration and recovery index of group ll and lll (35.20+/-2.30 and 16.20+/-1.37 min., 52.60+/-3.98 and 25.47+/-3.78min., respectively) were longer than those in group l (24.87+/-1.59 and 10.66 +/- 1.23 min.). But group l had a lower TOF ratio(27.40+/-3.09%) at 75% single twitch recovery than group ll and lll (41.87+/-3.25 and 45.27+/-3.67%, respectively). The increase in duration and the recovery index of group lll were greater than that of group ll. It was concluded that ketamine woudly potentiate the neuromuscular action of vecuronium in a dose-dependent manner. We suggest that combination of ketamine and vecuronium requires careful postoperative neuromuscular monitoring for the recovery from a vecuronium induced neuromuscular block.
Humans ; Ketamine* ; Neuromuscular Agents ; Neuromuscular Blockade* ; Neuromuscular Monitoring ; Succinylcholine ; Thiopental ; Vecuronium Bromide

No abstract available.
Carcinoembryonic Antigen* ; Colorectal Neoplasms* ; Humans

Bilateral coronoid hyperplasia causes painless progressive trismus, resulting from coronoid process impingement on the posterior aspect of the zygomatic bone. The etiology of coronoid hyperplasia is unclear, with various theories proposed. An endocrine stimulus, increased temporalis activity, trauma, genetic inheritance and familial occurrence have all been proposed, but no substantive evidence exists to support any of these hypotheses. Multiplanar reformatting of axial scans and 3-dimensional reconstruction permit precise reproduction of the shape and size of the coronoid and malar structures, and relationships of all structures of the temporal and infratemporal fossae. This case shows remarkably increased mouth opening by coronoidectomy in a patient who complained of trismus due to hyperplasia of coronoid process.
Humans ; Hyperplasia* ; Mandible ; Mouth ; Reproduction ; Trismus* ; Wills

OBJECTIVES: The aim of this study is to investigate the correlation between 2-dimensional (2D) cephalometric measurement and 3-dimensional (3D) cone beam computed tomography (CBCT) measurement, and to evaluate the availability of 3D analysis for asymmetry patients. MATERIALS AND METHODS: A total of Twenty-seven patients were evaluated for facial asymmetry by photograph and cephalometric radiograph, and CBCT. The 14 measurements values were evaluated and those for 2D and 3D were compared. The patients were classified into two groups. Patients in group 1 were evaluated for symmetry in the middle 1/3 of the face and asymmetry in the lower 1/3 of the face, and those in group 2 for asymmetry of both the middle and lower 1/3 of the face. RESULTS: In group 1, significant differences were observed in nine values out of 14 values. Values included three from anteroposterior cephalometric radiograph measurement values (cant and both body height) and six from lateral cephalometric radiographs (both ramus length, both lateral ramal inclination, and both gonial angles). In group 2, comparison between 2D and 3D showed significant difference in 10 factors. Values included four from anteroposterior cephalometric radiograph measurement values (both maxillary height, both body height) and six from lateral cephalometric radiographs (both ramus length, both lateral ramal inclination, and both gonial angles). CONCLUSION: Information from 2D analysis was inaccurate in several measurements. Therefore, in asymmetry patients, 3D analysis is useful in diagnosis of asymmetry.
Cephalometry ; Cone-Beam Computed Tomography ; Facial Asymmetry ; Humans ; Malocclusion

The authors would like to delete the acknowledgement part.

Adrenergic Fibers ; Humans ; Male ; Mandibular Condyle ; Regeneration ; Sweat ; Sweat Glands ; Sweating ; Sweating, Gustatory ; Young Adult

The authors note that the units on page 188 were reported incorrectly.

BACKGROUND: Micro-needle patches have been recently used to increase skin permeability, which improves drug delivery, and for cosmetic purposes. However, these patches may often have limited efficacy due to insufficient skin penetration and reduced compliance caused by discomfort. OBJECTIVE: We evaluated the efficacy and the safety of soluble micro-spicule containing epidermal growth factor (MS-EGF) for the treatment of periocular wrinkles. METHODS: Twenty healthy volunteers aged 33 to 54 years were enrolled in a randomized, controlled, split-face study. For 4 weeks, a periocular wrinkle was treated daily with either a soluble MS-EGF cream or a cream containing EGF alone. All subjects underwent 8 weeks of follow-up. Efficacy was assessed using an ultrasonic measurement of dermal depth and density, digital skin image analysis, 5-point photonumeric scale for periocular wrinkles and subjective satisfaction. RESULTS: MS-EGF group showed statistically significant increase of dermal depth and density compared to EGF alone group after 4 and 8 weeks. In addition, there was a marked improvement shown in clinical and 3-dimensional skin image in MS-EGF group. The treatments were well-tolerated; no significant side-effect was noted. CONCLUSION: The MS-EGF formulation may represent an effective and biocompatible advance in the treatment of periocular wrinkles.
Compliance ; Epidermal Growth Factor* ; Follow-Up Studies ; Healthy Volunteers ; Permeability ; Skin ; Ultrasonics

With the advent of magnetic resonance image (MRI), direct visualization of the spinal cord tumors and their relationship to the surrounding structures becomes possible. A clinical analysis was done retrospectively in forty patients suffering from primary spinal tumors and were treated surgically from November 1991 to November 1995. There were 19 male and 21 female patients, peak incidence occurs in the sixth decade of life. The tumor with the highest incidence was neurogenic tumor (42.5%), followed by glial tumor and meningioma. The most frequent symptom was pain. On radiological evaluation, simple plain X-ray showed abnormality in 37.5% of cases, in which the most common positive finding was pedicle erosion (20%). CT was performed in 38 cases and MRI in 31. The MRI reveals not only morphologic abnormalities but also diversities in signal intensity. These findings helped us to establish pathologic diagnosis and operative planning. Surgery was performed via anterior(5%) and posterior(95%) approaches. Total removal was possible in 70% of the cases and subtotal removal in 30%. Evaluation of the patient's symptom and neurologic deficit was done one month after operation, it was found that about 80% of the patients recovered or have their conditions improved. Complications were developed in 3 cases.
Diagnosis ; Female ; Humans ; Incidence ; Magnetic Resonance Imaging ; Male ; Meningioma ; Neurologic Manifestations ; Retrospective Studies ; Spinal Cord Neoplasms