1.Point mutation of K-ras oncogenes by paired polymerase chain reaction and gel electrophoresis in human colorectal cancers.
Woo Chan PARK ; Hae Myoung JEON ; Suk Kyun CHANG ; Sang Yong CHOO
Journal of the Korean Surgical Society 1993;44(1):1-10
No abstract available.
Colorectal Neoplasms*
;
Electrophoresis*
;
Genes, ras*
;
Humans*
;
Point Mutation*
;
Polymerase Chain Reaction*
2.Depressive Disorders among the College Students: Prevalence, Risk Factors, Suicidal Behaviors and Dysfunctions.
Myoung Sun ROH ; Hong Jin JEON ; Hae Woo LEE ; Hyo Jung LEE ; Sung Koo HAN ; Bong Jin HAHM
Journal of Korean Neuropsychiatric Association 2006;45(5):432-437
OBJECTIVES: The purpose of this study was to investigate the prevalence and correlates of major and minor depressive disorders in college students. METHODS: A cross-sectional study was completed on a sample of 906 students (507 men and 399 women) with the self-administered form of Korean version of Mini International Neuropsychiatric Interview (K-MINI). RESULTS: Estimated 12-month prevalence of major depressive disorder was 4.2% in men and 9.5% in women, and that of minor depressive disorder was 15.4% in men and 23.2% in women. The factors, 'female gender' and 'age of 20-21', were significantly associated with major depressive disorder. 'Poor adaptation to school' was significantly associated with major depressive disorder both in men and women, but 'poor interpersonal relationship' and 'history of school withdrawal' were associated only in men. Idea of self-injury and suicidal behaviors (suicidal ideation, plan and attempt) were significantly associated with major depressive disorder in women, but were not associated with minor depressive disorder. CONCLUSION: Major and minor depressive disorders are highly prevalent in the college students. Major depressive disorder was more associated with dysfunctions and suicidal behaviors than minor depressive disorder. Campus-based mental health service is needed for the high-risk students.
Cross-Sectional Studies
;
Depressive Disorder*
;
Depressive Disorder, Major
;
Female
;
Humans
;
Male
;
Mental Health Services
;
Prevalence*
;
Risk Factors*
3.Suicide-Related Behaviors among the College Students.
Myoung Sun ROH ; Hong Jin JEON ; Hae Woo LEE ; Hyo Jung LEE ; Sung Koo HAN ; Bong Jin HAHM
Journal of Korean Neuropsychiatric Association 2007;46(1):35-40
OBJECTIVES: This study evaluated the prevalence of suicide-related behaviors (suicidal ideation, plan and attempt) and the status of depression, anxiety and function in college students. METHODS: A cross-sectional study was completed to a sample of 880 students with the self-administered form of Korean version of the Mini International Neuropsychiatric Interview (K-MINI), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). RESULTS: Estimated lifetime prevalence of suicidal ideation was 39.2%, that of suicidal plan was 4.7% and that of suicidal attempt was 3.0%. Students with any suicide-related behaviors showed higher lifetime prevalence of major and minor depression, higher BDI and BAI scores, and poor interpersonal relationship, adaptation to college life and physical health compared to the students with no suicide-related behaviors. The average points of grades during their college life were not significantly different according to kinds of suicide-related behaviors they experienced (F=0.39, p=0.82). 96% of suicidal attempters did not use mental health services. CONCLUSION: Results suggest that a high proportion of college students experience suicide-related behaviors. The students who had experienced suicide-related behaviors showed higher depression and anxiety and poorer function compared to students with no suicide-related behaviors. Most of suicidal attempters, however, did not use mental health service. Establishing campus mental health system is necessary to early detect mental health problems and to prevent suicide of college students.
Anxiety
;
Cross-Sectional Studies
;
Depression
;
Depressive Disorder
;
Humans
;
Mental Health
;
Mental Health Services
;
Prevalence
;
Suicidal Ideation
;
Suicide
4.A Case Report of Anesthesia for Subtotal Pancreatectomy in a Patient with Nesidioblastosis.
Eun Hee JEON ; Joung Uk KIM ; Myoung Hoon KONG ; Hae Ja LIM ; Byoung Kuk CHAE ; Seong Ho CHANG
Korean Journal of Anesthesiology 1993;26(5):1051-1054
Nesidioblastosis is a rare disease characterized clinically by persistent hypoglycemia with inappropriately elevated circulating insulin concentration. Adequate early diagnosis should be established and subtotal pancreatectomy performed before itreversible cerebral damage caused by glucose deficit. The authors got a chance to anesthetize 56-day-old male patient for subtotal pancreatectomy because of nesidioblastosis, Following an induction of anesthesia with intravenous thiapental sodium 5 mg/kg and succinylchohne 1 mg/kg, endotracheal intubation was performed and anesthesia was maintained with pancuronium bromide and O2-N2O-enflurane. Intravenous fluid was maintained with 1-2-3 solution 30 ml and 15% D/W 40 ml mixed with 20 ml of 20 mEq/L NaCI.
Anesthesia*
;
Early Diagnosis
;
Glucose
;
Humans
;
Hypoglycemia
;
Insulin
;
Intubation, Intratracheal
;
Male
;
Nesidioblastosis*
;
Pancreatectomy*
;
Pancuronium
;
Rare Diseases
;
Sodium
5.The Anesthesia for Outpatient Facial Chemical Peeling Using Ketamine and Midazolam.
Eun Hee JEON ; Myoung Hun KONG ; Seong Ho CHANG ; Nan Suk KIM ; Hun CHO ; Hae Ja LIM
Korean Journal of Anesthesiology 1994;27(11):1575-1582
The surgeries based on the outpstient department have increased recently. One of the indications of outpatient surgery is chemical peeling of the face that usually re- quires only deep sedation of short duration. The purpose of this study was to evaluate the effeets of ketamine and midszolam for out patient facial chemical peeling. Fifty-nine unpremedicated patients undergoing chemical peeling of the face were anesthetized with bolus intravenous injection of 1mg/kg of ketamine and 0.1 mg/kg of midazolam. Additional dose of ketamine(10-20mg) was given as needed. During operation, we observed systolic and diastolic blood pressure with noninvasive blood pressure monitor and peripheral oxygen saturation(SpO2) with pulse oximeter. All patients were allowed to breathe spontane- ously without ventilatory support during the operation. There was no case of airway ob- struction and SpO2 value was over 97% in most cases. The systolic and diastolic blood pressure and pulse rate were increased after the injection of ketamine and midazolam. And we observed the untoward effect of anesthetics such as the purposeless movement(6.8%), involuntary phonation(3.4%), skin rash(3.4%) and headache(1.7%). In postoperative analysis about the recall, bad dream, mood, and the degree of satisfaction of this type of anesthesia, the rate of patient's positive acceptance was high(86.4%) and the reeovery time was 58min. We conclude that combination of intravenous ketamine and midszolam can produce satisfactory anesthesia with few complications for outpatient chemical peeling surgery of the face.
Ambulatory Surgical Procedures
;
Anesthesia*
;
Anesthetics
;
Blood Pressure
;
Blood Pressure Monitors
;
Deep Sedation
;
Dreams
;
Heart Rate
;
Humans
;
Injections, Intravenous
;
Ketamine*
;
Midazolam*
;
Outpatients*
;
Oxygen
;
Skin
6.Evaluation of Independent Risk Factors Affecting Renal Allograft Survival by Transplant Era.
Yu Seun KIM ; Soon Il KIM ; Myoung Soo KIM ; Kyu Ha HUH ; Man Ki JU ; Dong Jin JOO ; Hae Jin KIM ; Kyung Ock JEON ; Hyun Jung KIM ; Kiil PARK
The Journal of the Korean Society for Transplantation 2012;26(3):178-187
BACKGROUND: Using long-term (more than 30 years) data from a single center, this retrospective study evaluated changes of independent risk factors affecting renal allograft survival by transplant era. METHODS: Of 3,000 cases of kidney transplantation, 2,708 (90.3%), including their follow-up observations, were reviewed. Transplant era was classified according to immunosuppressive regimens as either early group (transplant serial No. 1~1,500) or recent group (transplant serial No. 1,501~3,000). RESULTS: There was a significant difference observed in pre-transplant clinical manifestations between the early and recent groups. The number of elderly recipients and donors, number of deceased donors, and cases related to pre-transplant diabetes, pre-emptive transplantation, and retransplantation were differed relative to transplant era. The short- and long-term graft survival rate of the recent group improved significantly, and the effect of human leukocyte antigen mismatching and living donor type disappeared in the recent group. Moreover, pre-emptive transplantation and retransplantation were effective only in the recent group. However, non-immunological factors such as elderly recipients and donors, and immunologic factors such as episodes of acute rejection and types of immunosuppressive regimen were persistent independent risk factors affecting graft survival rate. CONCLUSIONS: According to the retrospective survival analysis of a large number of recipients in a single center, risk factors for kidney transplant patients differed by transplant era. However, the independent risk factors associated with elderly recipients and donors (non-immunologic), and episodes of acute rejection, and types of immunosuppressive regimen (immunologic) persisted regardless of transplant era.
Aged
;
Follow-Up Studies
;
Graft Survival
;
Humans
;
Immunologic Factors
;
Kidney
;
Kidney Transplantation
;
Leukocytes
;
Living Donors
;
Rejection (Psychology)
;
Retrospective Studies
;
Risk Factors
;
Tissue Donors
;
Transplantation, Homologous
;
Transplants
7.Gallbladder Agenesis.
Ki Suk KIM ; Hae Myoung JEON ; Hun CHOI ; Jeong Soo KIM ; Jae Sung KIM ; Eu Gene KIM ; Kyoung A CHUN
Korean Journal of Hepato-Biliary-Pancreatic Surgery 1999;3(1):99-102
Gallbladder agenesis is a rare condition of hepatobiliary congenital anomaly. It is caused by failure of development of the caudal division of the primitive hepatic diverticulum or failure of vacuolization after the solid phase of embryonic development. It is divided into 2 groups: (1) those whose conditions are discovered clinically because of persistent symptoms and proven by abdominal exploration with operative cholangiography; and (2) those who are asymptomatic during life and whose conditions are discovered only at necropsy. If symptoms are present, they are unlikely to be related to gallbladder disease. It is impossible, at present, to make a preoperative diagnosis of gallbladder agenesis. Operative cholangiography is absolutely necessary to rule out an intrahepatic gall bladder. Confirmation at surgery and autopsy requires thorough dissection of the biliary tract and liver bed. Therefore, we presented this case with a brief review of the related literature.
Autopsy
;
Biliary Tract
;
Cholangiography
;
Diagnosis
;
Diverticulum
;
Embryonic Development
;
Female
;
Gallbladder Diseases
;
Gallbladder*
;
Liver
;
Pregnancy
;
Urinary Bladder
8.The Early Experience with a Totally Laparoscopic Distal Gastrectomy.
Jin Jo KIM ; Gyo Young SONG ; Hyung Min CHIN ; Wook KIM ; Hae Myoung JEON ; Cho Hyun PARK ; Seung Man PARK ; Keun Woo LIM ; Woo Bae PARK ; Seung Nam KIM
Journal of the Korean Gastric Cancer Association 2005;5(1):16-22
PURPOSE: In Korea, the number of laparoscopy-assisted distal gastrectomies for early gastric cancer patients has been increasing lately. Although minimally invasive surgery is more beneficial, no reported case of a totally laparoscopic distal gastrectomy has been reported because of difficulty with intracorporeal anastomosis. This study attempts, through our experiences, to determine the feasibility of a totally laparoscopic distal gastrectomy using an intracorporeal gastroduodenostomy in treating early gastric carcinoma. MATERIALS AND METHODS: We investigated surgical results and clinicopatholgic characteristics of eight(8) patients with an early gastric carcinoma who underwent a totally laparoscopic distal gastrectomy at the Department of Surgery, Our Lady of Mercy Hospital, The Catholic University of Korea, between June 2004 and September 2004. The intracorporeal gastroduodenostomy was performed with a delta-shaped ananstomosis by using only laparoscopic linear staplers (Endocutter 45 mm; Ethicon Endosurgery, OH, USA). RESULTS: The operative time was 369.4+/-62.5 minutes (range 275~65 minutes), and the anastomotic time was 45.1+/-14.4 minutes (range 32~0 minutes). The anastomotic time was shortened as surgical experience was gained. The number of laparoscopic linear staplers for an operation was 7.1+/-0.6. The number of lymph nodes harvested was 31.9+/-13.1. There was 1 case of transfusion and no case of conversion to an open procedure. The time to the first flatus was 2.8+/-0.5 days, and the time to the first food intake was 4.1+/-0.8 days. There were no early postoperative complications, and the postoperative hospital stay was 10.0+/-3.9 days. CONCLUSION: A totally laparoscopic distal gastrectomy using an intracorporeal gastroduodenostomy with a delta-shaped anastomosis is technically feasible and can maximize the benefit of laparoscopic surgery for early gastric cancer.
Conversion to Open Surgery
;
Eating
;
Flatulence
;
Gastrectomy*
;
Humans
;
Korea
;
Laparoscopy
;
Length of Stay
;
Lymph Nodes
;
Operative Time
;
Postoperative Complications
;
Stomach Neoplasms
;
Surgical Procedures, Minimally Invasive
9.Cardiac arrests in placenta accreta patient during emergency cesarean section: A case report.
Hea Jo YOON ; Joo Yeon JEON ; Myoung Goo KIM ; Pil Moo LEE ; Hae Kwang LEE ; Young Chul SHIN ; Jae Hoon BYUN ; In Ho LEE ; Young Seok JEE
Anesthesia and Pain Medicine 2013;8(2):132-135
We report the case of a patient who suffered two events of sudden cardiac arrests separately. Sudden onset of dyspnea and cardiac arrests occurred during cesarean section in a 35-year-old woman who delivered premature baby. Instant chest compression and epinephrine 1 mg was administered. She was diagnosed to have a placenta previa totalis with bleeding preoperatively and placenta accreta was noted intraoperatively. Cesarean hysterectomy was performed due to excessive hemorrhage associated with uterine atony. Another cardiac arrests occurred during hysterectomy. After instant successful resuscitation, she recovered her heart rhythm and transferred to tertiary hospital safely. She was discharged about two months later without any major physical or neurocognitive deficits.
Cesarean Section
;
Death, Sudden, Cardiac
;
Dyspnea
;
Emergencies
;
Epinephrine
;
Female
;
Heart
;
Heart Arrest
;
Hemorrhage
;
Humans
;
Hysterectomy
;
Placenta
;
Placenta Accreta
;
Placenta Previa
;
Pregnancy
;
Resuscitation
;
Tertiary Care Centers
;
Thorax
;
Uterine Inertia
10.Totally Laparoscopic Pylorus-preserving Gastrectomy with D2 Lymph Node Dissection.
Jin Jo KIM ; Kyo Young SONG ; Hyung Min CHIN ; Wook KIM ; Hae Myoung JEON ; Cho Hyun PARK ; Seung Man PARK ; Chang Jun AHN ; Keun Woo LIM ; Woo Bae PARK ; Seung Nam KIM
Journal of the Korean Surgical Society 2006;71(1):65-68
To improve postoperative quality of life, and to avoid postgastrectomy syndrome, pylorus-preserving gastrectomy (PPG) is considered as a good option in the middle third early gastric cancer. Convetional PPG has limitation in number 5 lymph node dissection because of preservation of blood supply and nerve innervation to the pylorus. To expand the indication of PPG, limitation on lymph node dissection must be overcomed. In case of laparoscopic PPG, there have been few reports in the literature. Herein we report a case of totally laparoscopic PPG with D2 lymph node dissection with review of literature.
Gastrectomy*
;
Laparoscopy
;
Lymph Node Excision*
;
Lymph Nodes*
;
Postgastrectomy Syndromes
;
Pylorus
;
Quality of Life
;
Stomach Neoplasms