1.Immunogenicity and reactogenicity of a yeast recombinant DNA hepatitis B vaccine in healthy subjects.
Kyo Myong KIM ; Sang Eun CHU ; Hae Ran LEE ; Hae Sun YOON ; Kyu Man LEE ; Chang Hong MIN
Journal of the Korean Society for Microbiology 1991;26(6):493-498
No abstract available.
DNA, Recombinant*
;
Hepatitis B Vaccines*
;
Hepatitis B*
;
Hepatitis*
;
Yeasts*
2.University Students' Health Behavior, Depression, and Ego-resilience.
Journal of Korean Academy of Psychiatric and Mental Health Nursing 2016;25(2):113-122
PURPOSE: The objectives of the study were to examine university students' health behavior, depression, and ego-resilience in order to understand the relationship between these variables, and to identify factors influencing ego-resilience. METHODS: Data were collected from a sample of 302 students attending G University. The data collection period was from October 28, 2015 to December 21, 2015. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation coefficients, and multiple regression with the SPSS Statistics version 23 Program. RESULTS: The number of close friends was weakly correlated with depression and ego-resilience: specifically, the number of close friends had a weak negative correlation with depression, and a weak positive correlation with ego-resilience. Factors significantly influencing the students' ego-resilience were depression, type of residence, frequency of exercise, and gender, with a total explanatory power of 18%. CONCLUSION: These findings indicate that intervention programs to improve ego-resilience should be developed. Research into ego-resilience should be replicated with students from a variety of cultural background and diverse study areas.
Data Collection
;
Depression*
;
Friends
;
Health Behavior*
;
Humans
3.The Effects of Combination of Fentanyl with Morphine in Intravenous Patient-Controlled Analgesia.
Hee Dong YOON ; Tae Il KIM ; Hun CHO ; Hye Won LEE ; Hae Ja LIM ; Suk Min YOON ; Seong Ho CHANG
Korean Journal of Anesthesiology 1998;35(5):975-982
Background: The highly lipid soluble opioid, fentanyl, has a rapid onset and short duration of action. The present study was designed to examine the analgesic efficacy and side effects of the combination of fentanyl with morphine in patients using intravenous PCA. Methods: Patients were randomly assigned to receive one of three PCA regimens: M4 group (40 mg morphine+90 mg ketorolac+1.5 mg dorperidol), M2F2 group (20 mg morphine+200 ug fentanyl+90 mg ketorolac+1.5 mg dorperidol), or M2F4 group (20 mg morphine+400 ug fentanyl+90 mg ketorolac+1.5 mg dorperidol). All patients were given initial loading dose of 0.1 mg/kg morphine plus 1 mg droperidol at the end of surgery. Pain score, side effects, and overall satisfaction were assessed at 30 min, 1 hr, 8 hr, 24 hr, and 48 hr postoperatively. Results: The pain score was significantly higher in the M2F2 group than in the M4 group and M2F4 group during 1 hr and 8 hr postoperatively. The total opioid consumption was significantly greater in the M2F4 group than in the M4 group. Patient satisfaction was better in the M2F4 than other two groups. There were no differences in the overall incidence of side effects among three groups. Conclusions: The present results suggest that the combination of fentanyl with morphine for intravenous patient-controlled analgesia is a useful method, and the double dose of fentanyl in comparison with the equipotent morphine dose is recommended in the early postoperative period.
Analgesia, Patient-Controlled*
;
Droperidol
;
Fentanyl*
;
Humans
;
Incidence
;
Morphine*
;
Passive Cutaneous Anaphylaxis
;
Patient Satisfaction
;
Postoperative Period
4.A case of ossifying fibroma involving the maxillary and ethmoidsinuses and nasal cavity.
Hun Mook CHOI ; Hae Sang CHUNG ; Sung Chul YOON ; Young Min KIM ; Young Min PARK ; Kyu Sik CYN
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):172-177
No abstract available.
Fibroma, Ossifying*
;
Nasal Cavity*
5.The Preventive Effect of Lidocaine on the Withdrawal Associated with the Injection of Rocuronium in Children.
Seong Ho CHANG ; Hae Young KIM ; Ji Yong PARK ; Hye Won LEE ; Hae Ja LIM ; Suk Min YOON
Korean Journal of Anesthesiology 2004;46(6):665-669
BACKGROUND: For pediatric anesthesia we frequently use rocuronium bromide, which is often associated with a localized withdrawal of the arm or generalized movements, that may cause harm to the patient. Lidocaine is said to be one of the better agents and reduce the incidence of movement associated with rocuronium injection in adults. The purpose of this study was to compare the effects on movement associated with rocuronium injection according to the method of lidocaine administration in children. METHODS: Two hundreds and four pediatric patients undergoing general anesthesia were randomly assigned to one of six groups (each group n = 34). Fifty seconds after the injection of thiopental sodium 5 mg/kg, the SM group was given mixture of rocuronium bromide 0.6 mg/kg and normal saline 0.05 ml/kg (same amount of 2% lidocaine 1 mg/kg) for 5-10 seconds. The LM 1.0 and LM 2.0 groups were given a mixture of rocuronium bromide 0.6 mg/kg and 2% lidocaine 1 mg/kg or 2 mg/kg, respectively. The LS 1.0, LS 1.5 and the LS 2.0 groups were given 2% lidocaine 1.0 mg/kg, 1.5 mg/kg, and 2.0 mg/kg respectively, 50 seconds after the injection of thiopental sodium, and rocuronium was given 5 seconds after the administration of lidocaine. Withdrawal movements after the injection of rocuronium were investigated. RESULTS: All of the SM group showed withdrawal movement and the LM 2.0, LS 1.0, LS 1.5, and LS 2.0 groups showed less withdrawal movement than the SM group. And the LS 1.0, LS 1.5, and LS 2.0 groups showed less movement than the LM 1.0 group. LS 2.0 group showed less withdrawal movement than LM 2.0 group. CONCLUSIONS: The sequential administration of lidocaine and rocuronium produced a better result than the administration of a mixture in terms of reducing withdrawal movement on rocuronium injection.
Adult
;
Anesthesia
;
Anesthesia, General
;
Arm
;
Child*
;
Humans
;
Incidence
;
Lidocaine*
;
Neuromuscular Blockade
;
Thiopental
6.A Clinicl Analysis of 85 Cases of Thyroid Nodules.
Min Seog HONG ; Ma Hae CHO ; Chan Heun PARK ; Yoon Kyu PARK
Journal of the Korean Surgical Society 1997;53(6):786-794
No abstract available.
Thyroid Gland*
;
Thyroid Nodule*
7.Autommune Hemolytic Anemia Associated with Extracorporeal Circulation.
Suk Min YOON ; Hae Ja LIM ; Byung Te SUH
Korean Journal of Anesthesiology 1985;18(1):107-112
We noted hemoglobinuris during and after extracorporeal circulation for one case of mitral valve replacement. Laboratory results revealed autoimmune hemolytic anemia(AIHA) including a positive direct Coombs test. A patient with AIHA is serologically incompatible with his own red cells and with the red cells of most blood donors. Red cell transfusion is essential for the management of life threatenting anemia especially in this case. So it is essential, therefore, to have efficient clinician blood bank communication in order to arrive at a rational transfusion therapy for these patients.
Anemia
;
Anemia, Hemolytic*
;
Blood Banks
;
Blood Donors
;
Coombs Test
;
Extracorporeal Circulation*
;
Humans
;
Mitral Valve
8.Effect of Morphine on c-fos Expression of Incisional Pain Rat Brain.
Hae Wone CHANG ; Jong Hyun YOON ; Chong Min PARK
Korean Journal of Anesthesiology 2004;47(3):419-424
BACKGROUND: Not many recent studies have shown that morphine antinociception may be directly expressed in forebrain structures. It is generally accepted that c-fos is a marker of neuronal activity and its expresson is correlated with nerve pathway activated by nociceptive stimuli. The aim of this study is to examine the effect of morphine on c-fos expression in the incisional pain rat brain. METHODS: A 1 cm longitudinal incision was made through the skin, fascia and muscle of the plantar aspect of the hindpaw in enflurane-anesthetized rats. 10 mg/kg of morphine was injected intraperitoneally 1 hour before (pre-morphine group; n = 15) and 30 minutes after surgery (post-morphine group; n = 15). The same amount of saline was injected 30 minutes after surgery (control group; n = 15). Two hours later c-fos protein expressions in the thalamus, hypothalamus, cerebral cortex and amygdala were examined by immunohistochemistry using a specific antibody. RESULTS: Numerous c-fos positive cells were observed in thalamus, hypothalamus, cerebral cortex, and amygdala in all groups. There were no significant differences in c-fos expression between pre-morphine, post-morphine and control group (P <0.05). CONCLUSIONS: In this study we expected to decreased c-fos expression in incisional pain rat brain by morphine injection. But no differences were observed compared to control group in thalamus and cortex which transmitting pain to CNS, also in hypothalamus and amygdale which transmitting emotional stress to CNS. These results suggests that intraperitoneal morphine can not protect the c-fos expression of ascending pathway to thalamus, hypothalmus, amygdala and cerebral cortex. Also we can not support the effect of morphine on the descending pathway of pain. So we thought for the more information, additional study, for example, behavior test, PCR (polymerase chain reaction)study, may be needed.
Amygdala
;
Animals
;
Brain*
;
Cerebral Cortex
;
Fascia
;
Hypothalamus
;
Immunohistochemistry
;
Morphine*
;
Neurons
;
Polymerase Chain Reaction
;
Prosencephalon
;
Rats*
;
Skin
;
Stress, Psychological
;
Thalamus
9.The Effect of Cardiovascular and Arterial Blood Gas Changes during Laparoscope Assisted Vaginal Hysterectomy (LAVH).
Woon Young KIM ; Hae Ja LIM ; Suk Min YOON ; Young Chul PARK
Korean Journal of Anesthesiology 1994;27(7):800-807
In the last decade, advances in laparoscopic equipments have allowed the development of laparoscopic surgical treatment for gynecologic affeetion. The purpose of this study is to investigate the cardiovascular effects and blood gas changes during laparoscope assisted vaginal hysterectomy (LAVH) in Trendelenburg position and intraabdominal CO2 insufflation to obtain optimal surgical field. Mean arterial pressure (MAP), heart rate. SaO2, PaO2, end-tidal CO2 (ETCO2) PaCO2, pH, and peak airway pressure (PAP) were measured in twenty patients who underwent laparoscope assisted vaginal hysterectomy in Trendelenburg position and intraabdominal CO2 insufflation. Each measurement was taken immedistely after intubation (control), 15 minutes after Trendelenburg position, 30 minutes after CO2 insufflation, 15 minutes, 1 hour and 6 hrs. after CO2 deflation. ETCO2 and PAP were not measured 1 hour and 6 hrs. after deflation The results were as follows; 1) Mean arterial pressure and heart rate were decreased after Trendelenburg position, but increased after CO2 insufflation. 2) Arterial O2 saturation was decreased after CO2 insufflation, 1 hour after deflation 3) Arterial PO2 was decreased after CO2 insufflation. 4) End-tidal CO2 was increased after CO2 insufflation. 5) Arterial PCO2 was increased after CO2 insufflation compared to control value, but it was decreased at 15 minutes after CO2 deflation. Arterial PCO2 at 1 hour after CO2 deflation was higher than at 15 minutes after CO2 deflation and 6 hrs. after CO2 deflation. 6) Arterial pH was decreased after CO2 insufflation. 7) Peak airway pressure was increased after Trendelenburg position and after CO2 insufflation.
Arterial Pressure
;
Female
;
Head-Down Tilt
;
Heart Rate
;
Humans
;
Hydrogen-Ion Concentration
;
Hysterectomy, Vaginal*
;
Insufflation
;
Intubation
;
Laparoscopes*
10.The Effect of Cardiovascular and Arterial Blood Gas Changes during Laparoscope Assisted Vaginal Hysterectomy (LAVH).
Woon Young KIM ; Hae Ja LIM ; Suk Min YOON ; Young Chul PARK
Korean Journal of Anesthesiology 1994;27(7):800-807
In the last decade, advances in laparoscopic equipments have allowed the development of laparoscopic surgical treatment for gynecologic affeetion. The purpose of this study is to investigate the cardiovascular effects and blood gas changes during laparoscope assisted vaginal hysterectomy (LAVH) in Trendelenburg position and intraabdominal CO2 insufflation to obtain optimal surgical field. Mean arterial pressure (MAP), heart rate. SaO2, PaO2, end-tidal CO2 (ETCO2) PaCO2, pH, and peak airway pressure (PAP) were measured in twenty patients who underwent laparoscope assisted vaginal hysterectomy in Trendelenburg position and intraabdominal CO2 insufflation. Each measurement was taken immedistely after intubation (control), 15 minutes after Trendelenburg position, 30 minutes after CO2 insufflation, 15 minutes, 1 hour and 6 hrs. after CO2 deflation. ETCO2 and PAP were not measured 1 hour and 6 hrs. after deflation The results were as follows; 1) Mean arterial pressure and heart rate were decreased after Trendelenburg position, but increased after CO2 insufflation. 2) Arterial O2 saturation was decreased after CO2 insufflation, 1 hour after deflation 3) Arterial PO2 was decreased after CO2 insufflation. 4) End-tidal CO2 was increased after CO2 insufflation. 5) Arterial PCO2 was increased after CO2 insufflation compared to control value, but it was decreased at 15 minutes after CO2 deflation. Arterial PCO2 at 1 hour after CO2 deflation was higher than at 15 minutes after CO2 deflation and 6 hrs. after CO2 deflation. 6) Arterial pH was decreased after CO2 insufflation. 7) Peak airway pressure was increased after Trendelenburg position and after CO2 insufflation.
Arterial Pressure
;
Female
;
Head-Down Tilt
;
Heart Rate
;
Humans
;
Hydrogen-Ion Concentration
;
Hysterectomy, Vaginal*
;
Insufflation
;
Intubation
;
Laparoscopes*