No abstract available.
Carcinoma, Renal Cell* ; Carcinoma, Squamous Cell* ; Cervix Uteri* ; Female ; Kidney*

No abstract available.
Skin*

School foodservice customers are likely to be tired of repeated cycle menus and their satisfaction for meals offered in school is inclined to be low. The menu variety is an important factor in increasing customer satisfaction. The purpose of this study was to investigate customer perspectives for applying rice based bread menus in order to add menu variety and promote using rice processed products in school foodservice. The questionnaire was distributed to 760 parent samples in elementary schools and 520 student samples in middle/high schools and a total of 665 and 387 usable data were collected, respectively. Food habits such as preference for cooking method, menu preference, food allergy and nutritional perspectives for menu and customer perception for rice based bread like quality, reliability, price, and purchasing convenience were investigated using 7 Likert scale. Also expected menu types applying rice based bread and offering frequency of rice bread menu were examined. Preference level for bread-based meals were moderate and students' preferences were slightly higher than parents. Menu types applying rice bread expected by middle/high school students were western food (49.4%), spaghetti (28.4%), set menu (13.7%), noodle (17.6%), Korean food (11.1%), Chinese food (10.9%) and porridge (4.5%). The most occupied rate was once in a week for expected offering frequency. Most respondents perceived that rice bread was more nutritive and qualitative than the wheat based one.
Asian Continental Ancestry Group ; Bread ; Cooking ; Surveys and Questionnaires ; Food Habits ; Food Hypersensitivity ; Food Preferences ; Humans ; Hypersensitivity ; Meals ; Parents ; Triticum

Background: The AdvanSure TB/NTM plus real-time PCR (AdvanSure plus PCR; LG Chem., Korea) assay has been developed to increase the diagnostic sensitivity of nontuberculous mycobacteria (NTM) compared with the currently used the AdvanSure TB/NTM real-time PCR (AdvanSure PCR;LG Chem., Korea) assay. In this study, we aimed to evaluate the performance of the AdvanSure plus PCR comparing the results with mycobacterial culture and the AdvanSure PCR. Methods: Patients (n=199) with suspected NTM or Mycobacterium tuberculosis complex (MTC) were tested using AdvanSure plus PCR, AdvanSure PCR, acid-fast bacilli staining, and mycobacteria culture. Additionally, 200 DNA samples (n=100, MTC and n=100, NTM) were obtained from positive MTC or NTM cultures for evaluation using the AdvanSure plus PCR assay. Results: The two real-time PCR systems showed a 94.0% (n=187/199) concordance rate (Kappa=0.94). Based on culture results, the sensitivity and specificity for the detection of MTC were 100% (45/45) and 83.8% (129/154) using AdvanSure plus PCR, and 100.0% (45/45) and 99.3% (153/154) using AdvanSure PCR, respectively. The sensitivity and specificity for NTM detection were 68.0% (n=17/25) and 90.2% (n=157/174), respectively, with AdvanSure plus PCR, and 64.0% (n=16/25) and 95.4% (n=166/174), respectively, using AdvanSure PCR. With culturepositive samples, AdvanSure plus PCR tested positive for 100% of both the MTC and NTM specimens. Seven (out of 200) culture-positive samples tested positive for both MTC and NTM using the AdvanSure plus PCR. Conclusion AdvanSure plus PCR had increased sensitivity but decreased specificity compared with AdvanSure PCR for the detection of NTM. The AdvanSure plus PCR assay can be used for the simultaneous detection of MTC and NTM in direct specimen and culture.

Maturity-onset diabetes of the young (MODY) is caused by autosomal dominant pathogenic variants in one of 14 currently known monogenic genes. Characteristics of patients with MODY include early-onset clinical disease with a family history of diabetes and negative autoantibodies and may present with heterogeneous phenotypes according to the different subtypes. Here, we report a patient with early-onset diabetes who presented asymptomatic mild fasting hyperglycemia with the absence of autoantibodies. She was diagnosed with glucokinase (GCK)-MODY caused by a GCK variant, c.1289T>C (p.L430P), identified by targeted gene-panel testing, and the affected father had the same variant. We interpreted this rare missense variant as a likely pathogenic variant and then she stopped taking oral medication. This case highlights the usefulness of genepanel testing for accurate diagnosis and appropriate management of MODY. We also note the importance of familial genetic testing and genetic counseling for the proper interpretation of MODY variants.

PURPOSE: The purpose of this study was to investigate nurses' perceptions on child abuse. METHODS: In this cross-sectional descriptive study, data were collected using a questionnaire and 217 nurses working in seven general hospitals were surveyed. The perception scale was divided into 4 subscales: physical, psychological, sexual abuse and neglect. RESULTS: Nurses who suspected child abuse accounted for 18.1% of the nurses, and 41.9% of the nurses stated that they did not to report suspected child abuse. The nurses reported receiving only a little education about the prevention of child abuse. The mean score for perception on child abuse was high (3.59±0.31). Recognition of sexual abuse ranked highest, psychological abuse ranked lowest. CONCLUSION: The findings from this research provide baseline information for understanding nurses' perceptions on child abuse, and may help in the development of appropriate education programs that will enable nurses to report child abuse.
Child ; Child Abuse* ; Child* ; Education ; Hospitals, General ; Humans ; Sex Offenses

PURPOSE: We evaluate the clinical outcomes after wavefront-guided (WFG) Epi-LASIK in mild and moderate myopia . METHODS: The uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), manifest refraction, total high order aberrations, contrast sensitivity for day and night vision, and pain score in 114 eyes of 61 patients who had undergone WFG Epi-LASIK were measured preoperatively and at 1 day, 1 week, 1 month, 2 months, and 6 months postoperatively. RESULTS: At 1 day, 1 week, 1 month, 2 months and 6 months postoperatively, UCVA & BCVA had improved significantly. At 1 month postoperatively, the spherical equivalent was -0.93+/-0.74 and showed a stable pattern at 6 months postoperatively. There was no statistically significant difference in total high-order aberration between preoperatively measurements and measurements taken at 6 months postoperative (p=0.745). At a frequency of 19 cpd, night contrast sensitivity showed significant statistical difference (p=0.010) but no difference at low and medium frequencies between preoperative measurements and postoperative six months measurements. Pain subsided at 2 weeks postoperative. All patients maintained clear cornea and suffered no complications. CONCLUSIONS: At 6 months postoperatively, patients who underwent Wavefront-guided Epi-LASIK showed successful results for the correction of moderate myopia and excellent contrast sensitivity at night time. Wavefront-guided Epi-LASIK may solve the visual quality problem after refractive surgery and, therefore, may be clinically useful.
Contrast Sensitivity ; Cornea ; Follow-Up Studies* ; Humans ; Myopia ; Night Vision ; Refractive Surgical Procedures ; Visual Acuity

BACKGROUND: Blood cultures are essential in diagnosing and treating sepsis. There are several factors that affect the diagnostic yield of blood cultures such as the number of blood sampling episodes, the incubation period, the type and volume of culture media, and the amount of blood drawn. This study aimed to elucidate whether monitoring the volume of blood drawn with an educational intervention could affect the diagnostic quality of blood cultures. METHODS: We implemented quality monitoring for the blood volume drawn during blood culture testing for adults in an emergency room. We instructed the nurses in the emergency room to draw the optimal amount of blood and to reduce the number of blood culture sets from three to two. We analyzed and compared the amount of blood drawn, the rate of positive blood cultures, the contamination rate, and time to positivity (TTP) between 908 patients pre-intervention and 921 patients post-intervention. RESULTS: The amount of blood drawn increased from 0.7±0.3 mL per bottle (pre-intervention) to 6.5±1.7 mL per bottle (post-intervention) (P<0.0001). The rate of positive blood culture post-intervention (12.14%) was higher than that pre-intervention (6.65%) (P<0.0001). The contamination rate post-intervention (1.82%) was also significantly greater than that pre-intervention (0.60%) (P<0.0001). Except for anaerobes, there was no significant difference in the distribution of microorganisms between the pre- and post-intervention periods. The TTP for anaerobe bottles post-intervention was significantly shorter than that of pre-intervention (16.1±16.3 versus 18.6±18.3 h). CONCLUSION: This study suggests that continuing education about adequate blood volume and aseptic techniques is needed to increase the rate of positive blood cultures and reduce the contamination rate of blood cultures.
Adult ; Blood Volume* ; Culture Media ; Education, Continuing ; Emergencies* ; Emergency Service, Hospital* ; Humans ; Sepsis

Subcutaneous pnniculitis-like T cell lymphoma (SPTCL) is a rare subtype of cutaneous T cell lymphoma which clinically and histopathologically mimics benign panniculitis. It presents as tender erythematous, subcutaneous nodules or plaques on the extremities and trunk, and displays systemic symptoms such as weight loss, fever, chills, fatigue or myaligia. The association of hemophagocytic syndrome (HPS) portends a poor prognosis. We report a case of SPTCL that occurred in a 20-month-old girl. She presented with multiple erythematous subcutaneous nodules on the face, right thigh, buttocks and trunk, plus fever and vomiting. Histopathological examination of the subcutaneous nodules revealed a dense infiltration of atypical T-lymphoid cells in the subcutaneous fat layer, with rimming of fat cells, numerous karyorrhetic bodies and histiocytes, phagocytosed apoptotic cells and Bean bag cells In spite of combination chemotherapy, she died of disseminated intravascular coagulation due to HPS.
Adipocytes ; Buttocks ; Chills ; Disseminated Intravascular Coagulation ; Drug Therapy, Combination ; Extremities ; Fatigue ; Female ; Fever ; Histiocytes ; Humans ; Infant ; Lymphohistiocytosis, Hemophagocytic* ; Lymphoma, T-Cell* ; Lymphoma, T-Cell, Cutaneous ; Panniculitis ; Prognosis ; Subcutaneous Fat ; Thigh ; Vomiting ; Weight Loss

There are many methods known to improve the effect of wound healing. Among them, low-power laser light have been used on the basis that it cause increase of new capillary formation, fibroblast, collagen synthesis, and blood flow. But there are some controversies, so the authors tried to prove the efficacy of low-power laser for wound healing on donor sites of skin graft. Performing this study, we also used hydrocelulla dressingr(Allevyn(R)), which is known to accelerate wound healing via providing a clean moist environment with its high absorption capacity, to compare the efficacy with that of low-power laser. We evaluated the wound healing results of fifty patients who underwent split-thickness skin graft for various reasons in Pusan National University Hospital from July 2000 to March 2001. Donor site wounds were formularized with the extent of 7 x 10cm2 width and 13/1000 inch depth on patients' thigh for accurate collection of data. Fifty patients were divided into five groups(n = 10 in each group) according to the method of treatment; Group I: hydrocellular drssing only, Group II: hydrocellular dressing and He-Ne laser, Group III: hydrocellular dressing, He-Ne and infrared (IR) laser, Group IV: hydrocellular dressing, He-Ne, infrared, and CO2 laser, and Group V: adaptive gauze dressing as a conventional method. All groups excluding group V were treated every other day. In laser treated groups, donor site wounds were subjected to irradiation with 500 Hz and 1 J/cm2. In assessing the efficacy of each treatmnet, time for complete epithelialization was assessed in all groups and all groups except for group V were examined every other day by questioning the patients about degree of pain according to the visual analogue pain scale(VAS) and calculated VAS improvement rate after treatment. As a result, laser treated groups(II, III and IV) were superior to hydroclullar dressing treated group(I), although the latter was more effective than the conventional group(V), in aspects of wound healing and pain relief. In conclusion, although hydrocellular dressing promotes wound healing in some aspects, low-power laser was more effective in wound healing and pain relief especially on donor site wounds after partial-thickness skin graft. We think that these low-power lasers with or without hydrocellualr dressing will be helpful in various fields of wound treatment as an adjunctive method.
Absorption ; Bandages* ; Busan ; Capillaries ; Collagen ; Fibroblasts ; Humans ; Lasers, Gas ; Skin ; Thigh ; Tissue Donors ; Transplants ; Wound Healing* ; Wounds and Injuries*