1.The development of industrial health information management system.
Sung Hyun HAN ; Young Moon CHAE ; Young Hahn MOON ; Jaehoon ROH ; Kyung Jong LEE ; Myung Wha CHO ; Hae Young MIN
Korean Journal of Occupational and Environmental Medicine 1992;4(2):181-189
No abstract available.
Information Management*
;
Occupational Health*
2.A Case of Vitiligo Coexistent with Neurofibromatosis Type 1.
Ho Jung JUNG ; Hae Jeong YOUN ; Nam Kyung ROH ; Yang Won LEE ; Yong Beom CHOE ; Kyu Joong AHN
Korean Journal of Dermatology 2015;53(8):656-658
No abstract available.
Neurofibromatoses*
;
Neurofibromatosis 1*
;
Neurofibromin 1
;
Vitiligo*
3.Health characteristics and symptom of workers in reactive dye industries.
Kyung Jong LEE ; Young Hahn MOON ; Jaehoon ROH ; Hae Sim PARK ; Chein Soo HONG
Korean Journal of Preventive Medicine 1990;23(3):338-344
This study investigated the symptoms, medical and occupational history of 424 workers of 5 reactive dye Industries in the Inchon area in Korea. The study was performed on March 6 and July 19, 1989. The tests applied to the subjects were: serum total IgE, skin prick test with 7 inhalatory antigens, pulmonary function test, chest X-ray, methacholine test, and bronchoprovocation test. The workers were classified according to these tests into 4 groups (healthy, realitively healthy, need careful medical observation, and occupational asthma), and were compared in terms of the group characteristics and the symptom prevalence. The prevalence of occupational asthma of workers in reactive dye was 5.9%. Significant differences were observed among the 4 groups. The groups were significantly different in the variables of sex and duration of smoking among their general characteristics ; asthma, bronchitis, and other respiratory diseases with respect to their past medical history. This study suggests that we should pay special attention to the workers exposed to the risk of occupational asthma.
Asthma
;
Asthma, Occupational
;
Bronchitis
;
Immunoglobulin E
;
Incheon
;
Korea
;
Methacholine Chloride
;
Prevalence
;
Respiratory Function Tests
;
Skin
;
Smoke
;
Smoking
;
Thorax
4.A Case of Corporis Showing Tinea Imbricata-like Clinical Appearance.
Doe Kywn ROH ; Chul Jong PARK ; Jong Yuk YI ; Hae Kyung LEE
Korean Journal of Medical Mycology 2000;5(1):20-23
We, here in, report a case of tinea corporis which shows tinea imbricata-like clinical appearance. A 19-year-old man was presented with a 40-day history of annular patches with polycyclic rings on the right forearm. KOH staining, culture, PAPD PCR revealed this lesion as tinea corporis by Trichophyton rubrum showing tinea imbricata-like clinical appearance.
Forearm
;
Humans
;
Polymerase Chain Reaction
;
Tinea*
;
Trichophyton
;
Young Adult
5.Biomechanical analysis of Korean Ilizarov Fixator.
Hae Ryong SONG ; Jae Young ROH ; Se Hyun CHO ; Kyung Hoi KOO ; Soon Taek JEONG ; Young June PARK ; Jong Hoon PARK ; Young Chan HAN
The Journal of the Korean Orthopaedic Association 1997;32(2):332-339
The purpose of this study is to evaluate biomechanical stability of Korean Ilizarov fixator before clinical application. We measured the ultimate tensile load and stiffness of Ilizarov smooth wire and olive wire, bending stiffness of half-pin, ultimate compressive load and stiffness of Ilizarov ring using Instron 1331. Four types of Ilizarov assembly were tested for measuring stiffness of axial compression, anteroposterior bending, and lateral bending. There were group I fixed with only smooth wires; group II with only olive wires; group III with wires and half-pins; and group IV with only half-pins. The results of Korean Ilizarov apparatus were compared to those of American Ilizarov apparatus using unpaired t-test. The ultimate tensile strength of Korean smooth wire was greater than that of American wire. The ultimate tensile strength of Korean olive wire was lower than that of American wire. There was no significant difference of stiffness of axial compression, anteroposterior bending, and lateral bending between American and Korean apparatus. There was no significant difference of axial compression stiffness and bending stiffness between group III and group IV. In conclusion, Korean Ilizarov apparatus can be used with good stability for treatment of fracture, internal bone transport, and limb lengthening according to this biomechanical study.
Extremities
;
Olea
;
Tensile Strength
6.Squamous Cell Carcinoma of the Rectum: Report of Two Cases.
Na Rae KIM ; Dong Hae CHUNG ; Jeong Heum BAEK ; Yeon Ho PARK ; Hee Eun KYUNG ; Mi Sook ROH ; Seung Yeon HA
Intestinal Research 2010;8(2):172-176
Squamous cell carcinoma of the rectum is extremely rare. Herein we report two cases of rectal squamous cell carcinoma. Case 1 was a 44-year-old Korean female presenting with abdominal pain and rectal bleeding for 3 months before her hospital visit. A colonoscopic examination revealed an ulcerated rectal mass 8 cm proximal to the anal verge. Chemoradiotherapy was administered following Hartmann's procedure in case 1. The patient remained alive during 19 months of follow up. Case 2 was a 43-year-old Korean female who had severe constipation for 2 months. A barium enema and computed tomography of the pelvis showed a rectal mass adherent to the sacrum. Based on the results of a colonoscopic biopsy, a diverting colostomy was performed in case 2, with no further treatment. The pathologic findings showed that both tumors were composed of oval-shaped cells with abundant eosinophilic cytoplasm and intercellular bridges with keratin pearls, and thus were diagnosed as well-differentiated squamous cell carcinoma. Neither of the cases showed evidence of HPV infection. The pathogenesis of rectal squamous cell carcinoma has not been clarified. Herein we report two cases of rectal squamous cell carcinoma and briefly discuss the possible histogenesis.
Abdominal Pain
;
Adult
;
Barium
;
Biopsy
;
Carcinoma, Squamous Cell
;
Chemoradiotherapy
;
Colostomy
;
Constipation
;
Cytoplasm
;
Enema
;
Eosinophils
;
Female
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Keratins
;
Pelvis
;
Rectum
;
Sacrum
;
Ulcer
7.Tissue and Serum Inflammatory Cytokine Levels in Korean Psoriasis Patients: A Comparison between Plaque and Guttate Psoriasis.
Nam Kyung ROH ; Song Hee HAN ; Hae Jeong YOUN ; Yu Ri KIM ; Yang Won LEE ; Yong Beom CHOE ; Kyu Joong AHN
Annals of Dermatology 2015;27(6):738-743
BACKGROUND: The phenotypic heterogeneity of psoriasis could be explained by the alternate activation of either T-helper (Th)-1- or Th-17-related cytokines. However, evidence directly supporting this hypothesis is scarce. OBJECTIVE: To characterize the expression of Th-1- and Th-17-related cytokines according to the morphological psoriasis phenotype: guttate vs. plaque. METHODS: In this study, we enrolled 68 patients exhibiting either guttate or plaque psoriasis, and 10 healthy controls. To avoid age-related bias, age matching was performed for each group. Circulating levels of interferon (IFN)-gamma, interleukin (IL)-1RA, IL-2, IL-12p40, IL-17A, IL-22, and IL-23 were measured with an enzyme-linked immunosorbent assay (ELISA). Psoriasis-affected tissue was obtained through biopsy sampling from the eight patients who exhibited the most typical morphology. Levels of IL-1RA, IL-12p40, IL-17, IL-22, and IL-23 in the psoriasis tissue samples were measured with western blot analysis. RESULTS: ELISAs of the serum samples showed higher levels of inflammatory cytokines such as IL-1RA, IL-2, IL-23, and IFN-gamma in patients with psoriasis than in healthy controls. However, the inflammatory cytokine levels did not differ significantly between guttate and plaque psoriasis patients. Western blot analysis of psoriatic tissue revealed higher protein levels of Th-1- and Th-17-related cytokines in patients than in healthy controls. The levels of IL-12p40 and IL-23 were unexpectedly higher in plaque tissue than in guttate tissue. CONCLUSION: The morphological phenotype of psoriasis does not appear to be determined by a specific activation of either the Th-1 or Th-17 pathway. Rather, the cytokine profile influences disease activity and is altered according to the status of the lesion (early or chronic).
Bias (Epidemiology)
;
Biopsy
;
Blotting, Western
;
Cytokines
;
Enzyme-Linked Immunosorbent Assay
;
Humans
;
Interferons
;
Interleukin 1 Receptor Antagonist Protein
;
Interleukin-12 Subunit p40
;
Interleukin-17
;
Interleukin-2
;
Interleukin-23
;
Interleukins
;
Phenotype
;
Population Characteristics
;
Psoriasis*
8.Cutaneous Pili Migrans in the Sole of a Pediatric Patient.
Hae Jeong YOUN ; Min Seok HUR ; Song Hee HAN ; Nam Kyung ROH ; Yang Won LEE ; Yong Beom CHOE ; Kyu Joong AHN
Korean Journal of Dermatology 2017;55(5):305-307
Cutaneous pili migrans is a rare condition in which a hair shaft migrates under the superficial skin. We report a case in which a 2-year-old boy presented with an unusually shaped long hair strand that had penetrated the epidermis of the sole. We discuss the structure and fragility of skin in children, which may predispose their skin to invasion by a foreign body, viz., a long hair strand.
Child
;
Child, Preschool
;
Dermoscopy
;
Epidermis
;
Foreign Bodies
;
Hair
;
Humans
;
Male
;
Skin
9.Drug Reaction with Eosinophilia and Systemic Symptom Syndrome Induced by Lamotrigine.
Song Hee HAN ; Min Seok HUR ; Hae Jeong YOUN ; Nam Kyung ROH ; Yang Won LEE ; Yong Beom CHOE ; Kyu Joong AHN
Annals of Dermatology 2017;29(2):206-209
Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a type of severe adverse drug-induced reaction. Dermatologists should make a quick diagnosis and provide appropriate treatment for DRESS syndrome to reduce mortality rates, which can be as high as 10%. We present the case of a 47-year-old man with schizoaffective disorder treated with lamotrigine who developed DRESS syndrome to emphasize the importance of close observation of patients with drug eruption. He was consulted for erythematous maculopapular rashes on the trunk that developed 3 weeks after starting lamotrigine. A few days later, he developed generalized influenza-like symptoms. The skin rashes spread over his entire body, and the sense of itching was rapidly aggravated within a few days. Increased liver enzyme levels and significant eosinophilia were found on laboratory test results. His condition was diagnosed as DRESS syndrome, and he was treated with systemic and topical corticosteroids for 2 weeks.
Adrenal Cortex Hormones
;
Anticonvulsants
;
Diagnosis
;
Drug Eruptions
;
Drug Hypersensitivity Syndrome
;
Eosinophilia*
;
Exanthema
;
Humans
;
Liver
;
Middle Aged
;
Mortality
;
Pruritus
;
Psychotic Disorders
10.Normal Development of Sutures and Synchondroses in the Central Skull Base: CT Study.
Hong Gee ROH ; Hyung Jin KIM ; Jee Hee KANG ; Kyung Hee LEE ; Myung Kwan LIM ; Young Kuk CHO ; Cheol Su OK ; Chang Hae SUH
Journal of the Korean Radiological Society 2000;42(2):215-225
PURPOSE: To evaluate the developmental patterns of the sutures and synchondroses in the central skull base. MATERIALS AND METHODS: We evaluated the CT scans of 109 children(age range, 29 days to 15 years) with no skull base abnormality who had undergone axial CT of the skull base with 1-mm collimation. Using a five-tier scheme, we analyzed the developmental patterns of the 18 sutures and synchondroses related to the sphenoid and occipital bones. RESULTS: Fusion of the sutures and synchondroses related to the sphenoid bone progressed rapidly during the first two years. Thereafter, changes in the sphenoid bone were dominated by pneumatization of the sphenoid sinus. Fusion of the synchondroses within the sphenoid body, including intersphenoidal, intrapresphenoidal, and intrapostsphenoidal synchondrosis occurred early and in most cases was graded <=4. Fusion of the sphenosquamosal, sphenoethmoidal, and frontosphenoidal sutures was delayed, and residual sclerosis was a common finding. Except for Kerckring-supraoccipital synchondrosis, fusion of the six sutures and synchon-droses related to the occipital bone occurred more gradually than that of those related to the sphenoid bone. Among these, fusion of the occipitomastoidal suture and petro-occipital synchondrosis was the last to occur. CONCLUSION: A knowledge of the developmental patterns of sutures and synchondroses can help differentiate normal conditions from those such as fracture, osseous dysplasia, or congenital malformation, which are abnormal. Our results provide certain basic informations about skull base maturity in children.
Child
;
Humans
;
Occipital Bone
;
Sclerosis
;
Skull Base*
;
Skull*
;
Sphenoid Bone
;
Sphenoid Sinus
;
Sutures*
;
Tomography, X-Ray Computed