While recently extending that research, however, the authors discovered that 236 members of the general population were mistakenly to be duplicated by the investigating agency (Word Research) and 1,241 were reported rather than 1,005. The authors present corrections and discuss the relevant data. The authors wish to apologize to the publisher and readers of Journal of Korean Medical Science for these errors.

While recently extending that research, however, the authors discovered that 236 members of the general population were mistakenly to be duplicated by the investigating agency (Word Research) and 1,241 were reported rather than 1,005. The authors present corrections and discuss the relevant data. The authors wish to apologize to the publisher and readers of Journal of Korean Medical Science for these errors.

The approval number of Institutional Review Board (IRB) was wrong in the article.

BACKGROUND: It is difficult to decide whether to inform the child of the incurable illness. We investigated attitudes of the general population and physicians toward prognosis disclosure to children and associated factors in Korea. METHODS: Physicians working in one of 13 university hospitals or the National Cancer Center and members of the general public responded to the questionnaire. The questionnaire consisted of the age appropriate for informing children about the prognosis and the reason why children should not be informed. This survey was conducted as part of research to identify perceptions of physicians and general public on the end-of-life care in Korea. RESULTS: A total of 928 physicians and 1,241 members of the general public in Korea completed the questionnaire. Whereas 92.7% of physicians said that children should be informed of their incurable illness, only 50.7% of the general population agreed. Physicians were also more likely to think that younger children should know about their poor prognosis compared with the general population. Physicians who opposed incurable illness disclosure suggested that children might not understand the situation, whereas the general public was primarily concerned that disclosure would exacerbate the disease. Physicians who were women or religious were more likely to want to inform children of their poor prognosis. In the general population, gender, education, comorbidity, and caregiver experience were related to attitude toward poor prognosis disclosure to children. CONCLUSION: Our findings indicate that physicians and the general public in Korea differ in their perceptions about informing children of poor prognosis.
Caregivers ; Child* ; Comorbidity ; Disclosure* ; Education ; Female ; Hospitals, University ; Humans ; Korea ; Prognosis ; Republic of Korea

Stent thrombosis is a rare, but potentially catastrophic complication of stent implantation. Dual antiplatelet therapy with aspirin and a thienopyridine (clopidogrel, prasugrel, or ticagrelor) is essential to minimize the risk of stent thrombosis in patients receiving drug-eluting stents. However, there is an ongoing debate regarding antiplatelet therapy in patients presenting with acute coronary syndrome and bleeding. Here, we report a case of a 59-year-old man with acute stent thrombosis immediately after percutaneous coronary intervention combined with acute coronary syndrome and gastrointestinal bleeding.
Acute Coronary Syndrome ; Aspirin ; Blood Transfusion ; Drug-Eluting Stents ; Gastrointestinal Hemorrhage ; Hemorrhage* ; Humans ; Middle Aged ; Percutaneous Coronary Intervention ; Stents* ; Thrombosis* ; Prasugrel Hydrochloride

Arthrobacter spp., which are coryneform gram-positive bacilli, are widely distributed in the environment, including soil. In humans, infection with Arthrobacter is recognized as an opportunistic infection. In particular, since the first reported case in 1996, human infection by A. woluwensis has been reported only four times. We report on a case of A. woluwensis bacteremia in a 76-year-old female patient with multiple myeloma. Performance of 16S rRNA gene sequence analyses resulted in identification of A. woluwensis. The patient was treated with teicoplanin, and the central venous port was removed. Since then, no growth has been observed on repeated blood cultures. The patient was discharged well after the fever subsided.
Aged ; Arthrobacter ; Bacteremia ; Female ; Fever ; Genes, rRNA ; Humans ; Multiple Myeloma ; Opportunistic Infections ; Sequence Analysis ; Soil ; Teicoplanin

This study examined whether amifostine (WR-2721) could attenuate memory impairment and suppress hippocampal neurogenesis in adult mice with the relatively low-dose exposure of acute radiation syndrome (ARS). These were assessed using object recognition memory test, the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay, and immunohistochemical markers of neurogenesis [Ki-67 and doublecortin (DCX)]. Amifostine treatment (214 mg/kg, i.p.) prior to irradiation significantly attenuated the recognition memory defect in ARS, and markedly blocked the apoptotic death and decrease of Ki-67- and DCX-positive cells in ARS. Therefore, amifostine may attenuate recognition memory defect in a relatively low-dose exposure of ARS in adult mice, possibly by inhibiting a detrimental effect of irradiation on hippocampal neurogenesis.
Acute Radiation Syndrome/drug therapy/*immunology/psychology ; Amifostine/*pharmacology/therapeutic use ; Animals ; Apoptosis/immunology ; Gamma Rays/*adverse effects ; Hippocampus/immunology ; Immunohistochemistry ; In Situ Nick-End Labeling ; Male ; Memory/*radiation effects ; Mice ; Mice, Inbred ICR ; Neurogenesis/immunology ; Radiation-Protective Agents/*pharmacology/therapeutic use

BACKGROUND: Catheter-related bacteremia is a frequent complication among hemodialysis patients using a tunneled cuffed catheter. The standard therapy of catheter-related bacteremia involves both systemic antibiotics and catheter replacement. This study was performed to evaluate the effect of antibiotic lock therapy in conjugation with systemic antibiotics without catheter removal on catheter-related bacteremia. METHODS: Thirty six chronic hemodialysis patients with tunneled cuffed catheter were monitored for infection between July 2001 and July 2005. We analyzed the efficacy of antibiotic lock protocol compared with systemic antibiotics alone. RESULTS: Twenty-nine episodes of catheter-related bacteremia occurred in 27 patients during the study periods. The incidence of catheter-related bacteremia was 1.5 episodes/1000 catheter-days. A single gram-positive coccus grew in the 16 cases (55.2 %), and gram-negative organisms grew in the 69 cases (31.0%). Sixteen of 18 patients (88.9%) treated with antibiotic lock protocol had successful catheter salvage versus only 6 of the 11 patients (54.5%) treated with systemic antibiotics alone (p=0.05). Three patients with Burkholderia pickettii and a patient with Acinetobactor calcoaceticus-baumannii complex were treated with antibiotic lock protocol with systemic ciprofloxacin and imipenem, respectively. CONCLUSION: This study suggests that antibiotic lock protocol in eradicating catheter-related bacteremia is effective treatment without requiring catheter replacement.
Anti-Bacterial Agents ; Bacteremia* ; Burkholderia ; Catheters ; Ciprofloxacin ; Humans ; Imipenem ; Incidence ; Renal Dialysis

The dengue virus causes dengue fever and dengue hemorrhagic fever. It is an arbovirus and is transmitted by mosquitoes, Aedes aegypti. Dengue fever is an acute viral illness characterized by fever, skin rash, severe headache, myalgia and arthralgia. Rabdomyolysis rarely occurs in dengue fever in contrast with other viral infections. In this case, the patient was suffering from fever and severe myalgia, especially both lower extremities, after traveling to Philippines. He was diagnosed with dengue fever complicated by rhabdomyolysis as a result of serologic test and bone scan. He completely recovered with conservative care and nutritional support. We experienced a case of dengue fever complicated by rhabdomyolysis, which was treated successfully with conservative care.
Aedes ; Arboviruses ; Arthralgia ; Culicidae ; Dengue Virus ; Dengue* ; Exanthema ; Fever ; Headache ; Humans ; Lower Extremity ; Myalgia ; Nutritional Support ; Philippines ; Rhabdomyolysis* ; Serologic Tests ; Severe Dengue

The dengue virus causes dengue fever and dengue hemorrhagic fever. It is an arbovirus and is transmitted by mosquitoes, Aedes aegypti. Dengue fever is an acute viral illness characterized by fever, skin rash, severe headache, myalgia and arthralgia. Rabdomyolysis rarely occurs in dengue fever in contrast with other viral infections. In this case, the patient was suffering from fever and severe myalgia, especially both lower extremities, after traveling to Philippines. He was diagnosed with dengue fever complicated by rhabdomyolysis as a result of serologic test and bone scan. He completely recovered with conservative care and nutritional support. We experienced a case of dengue fever complicated by rhabdomyolysis, which was treated successfully with conservative care.
Aedes ; Arboviruses ; Arthralgia ; Culicidae ; Dengue Virus ; Dengue* ; Exanthema ; Fever ; Headache ; Humans ; Lower Extremity ; Myalgia ; Nutritional Support ; Philippines ; Rhabdomyolysis* ; Serologic Tests ; Severe Dengue