2.Familial Lichen Planus.
Hyo Hyun AHN ; Dong Jun KIM ; Kil Ju LEE ; Hae Jun SONG ; Chil Hwan OH
Korean Journal of Dermatology 1998;36(3):473-476
Familial lichen planus is an uncommon disease, and there are 104 cases reported in the English literature. Several theories regarding the etiopathogenesis of lichen planus have been proposed. However, immunological mechanisms and genetic susceptibility have been emphasized the most. Several reports showed HLA analysis in lichen planus patients, and recently 2 cases have revealed an increased frequency of DR1 antigen in patients with lichen planus compared to a control group. We observed two brothers with typical skin lesions of lichen planus of almost simultaneous onset. We confirmed lichen planus by skin biopsies in both brothers and analyzed HLA typing. We also observed the occurrence of DR1 antigen in both of them.
Biopsy
;
Genetic Predisposition to Disease
;
Histocompatibility Testing
;
Humans
;
Lichen Planus*
;
Lichens*
;
Siblings
;
Skin
3.A Case of Cutaneous Ossification occurring in Pseudohypoparathyroidism.
Hyohyun AHN ; Ki Sung KIM ; Il Hwan KIM ; Hae Jun SONG ; Hae Won CHEON ; Joo Won LEE ; Chil Hwan OH
Annals of Dermatology 1999;11(4):263-266
In Albright's hereditary osteodystrophy (AHO) including the syndromes of pseudohypoparathyroidism (PHP) and pseudopseudohypoparathyroidism (PPHP), multiple areas of intracutaneous ossification are often encountered. The characteristic features are short stature, round face, short neck, obesity, cutaneous ossifications, and various skeletal anomalies including short metacarpal and metatarsal bones, curve of radius, and brachydactyly. The patient was a 10-month-old male infant. He presented slightly depressed erythematous hard plaques on the left upper chest and left thigh. We had taken biopsies from both skin lesions, confirming cutaneous ossification or bone formation. He also had the characteristic features of AHO. He had a history of admission due to patent ductus arteriosus and atrial septal defect. The laboratory results showed slightly decreased calcium, increased phosphorus and PTH levels. The patient received no specific corrective measures because his calcium and phosphorus levels were not far from normal values until newly developed similar skin lesions appeared.
Biopsy
;
Brachydactyly
;
Calcium
;
Ductus Arteriosus, Patent
;
Heart Septal Defects, Atrial
;
Humans
;
Infant
;
Male
;
Metatarsal Bones
;
Neck
;
Obesity
;
Osteogenesis
;
Phosphorus
;
Pseudohypoparathyroidism*
;
Pseudopseudohypoparathyroidism
;
Radius
;
Reference Values
;
Skin
;
Thigh
;
Thorax
4.A Case Combined Germ Cell Tumor in Testis.
Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE ; Jun Gyu SUH ; Kyung Chul LEE
Yeungnam University Journal of Medicine 1985;2(1):293-297
Primary germ cell tumor of the testis is rare, which occupies 1 to 2% of all reported malignant male neoplasms. Combined primary germ cell tumor of the testis composed of embryonal carcinoma and seminoma is more rare tumor. The authors experienced a case of 50-year old male who presented with painless enlargement of right testicle. He has had radical orchiectomy and diagnosed by pathologically as combined germ cell tumor of testis. The testicle is measuring 180 gm in weight and 9×6×5 cm in dimension, and almostly replaced by tumor mass. Grossly the tumor is rubbery solid smooth tumor mass, with variegated cut surface with geographically outlined diffuse necrotic area. Histologically the tumor is composed of two components of tumor, which are solid growth pattern of large round to polyhedral cells with clear or granular cytoplasm and distinct cell border, and anastomosing glandular and papillary arrangement of anaplastic epithelial cells. The former corresponds to seminoma, and the latter to embryonal carcinoma. Each tumor lobule is separated by abundant fibrous stroma.
Carcinoma, Embryonal
;
Cytoplasm
;
Epithelial Cells
;
Germ Cells*
;
Humans
;
Male
;
Neoplasms, Germ Cell and Embryonal*
;
Orchiectomy
;
Seminoma
;
Testis*
5.The Relationship between Human Neutrophil Elastase and Coronary Arterial Dilatation in Kawasaki Disease .
Jun Yong SHIM ; Hee Won CHOI ; Ja Hyun HONG ; Jong Kyun LEE ; Hae Yong LEE
Journal of the Korean Pediatric Society 2003;46(9):903-908
PURPOSE: Kawasaki disease is notorious for coronary arterial complication which is usually developed as a febrile disease in early childhood. Increased polymorphonucleus(PMN) cell levels in acute phases may be associated with the pathophysiology of Kawasaki disease. We studied the relationship between coronary arterial dilatation and elastase activity which was excreted from PMN cell and roles as an important factor for vasculitis. METHODS: Ten patients diagnosed with Kawasaki disease in Yonsei University Medical Center were examined between November, 2001 and January, 2002. In addition, 15 patients with other febrile diseases were also examined. Echocardiography was done in patients with Kawasaki disease on the first day of admission and four weeks after the onset of the disease. At each time, venous samples were drawn and separated into plasma and leukocytes. In patients with other febrile disease, samples were drawn on admission. Elastase activities in plasma and neutrophil extracts were measured. RESULTS: The significant increased plasma elastase activity, 6.19+/-0.74 U/mL, found in Kawasaki disease patients compared with the other febrile disease patients, 4.86+/-1.17 U/mL(P<0.05). And there was no significance between the above two diseases in terms of the elastase activity in neutrophil extracts. The relationship between initial elastase activity and the coronary arterial complication which was shown in subacute phase wasn't significant. CONCLUSION: Plasma elastase activity was increased in Kawasaki disease significantly, but the initial plasma elastase activity in the acute phase could not reflect the range of coronary arterial complication.
Academic Medical Centers
;
Dilatation*
;
Echocardiography
;
Humans*
;
Leukocyte Elastase*
;
Leukocytes
;
Mucocutaneous Lymph Node Syndrome*
;
Neutrophils*
;
Pancreatic Elastase
;
Plasma
;
Vasculitis
6.The 2 Cases of the Sacrospinous Ligament Fixation for the Massive Eversions of the Vagina after Total Abdominal Hysterectomy.
Kae Hyun NAM ; Kyung Jun CHOI ; Jeong Jae LEE ; Hae Hyeog LEE ; Kwon Hae LEE
Korean Journal of Obstetrics and Gynecology 1997;40(11):2626-2630
Massive eversion of the vagina is one of the most disturbing disorders confronting a woman. It is a complex disorder that always surgical, and all defects. The managements is always surgical, and all defects must be repaired concomitantly. Current surgical practice relies primarily on the strength of the endopelvic fascia and certain ligaments. Massive eversion of the vagina can be treated by a variety of transvaginal and transamdominal surgical technique. In most instances a transvaginal approach is useful. If strong cadinal and uteroscral support in not available fiocation of the vginal vault to the sacrospinous ligment is useful. In 1987, Miyazaki introduced his Miya Hook ligature carrier. With this instrume nt, introduction of the needle became safer and easier than with the Deschamp aneurysm needle. We had experienced two cases of massive eversion of vagina after the total abdominl hyst erectomy who were treated succesfully with sacrospinous ligement fixation by using Miya Hook. We report above two cases and review briefly.
Aneurysm
;
Fascia
;
Female
;
Humans
;
Hysterectomy*
;
Ligaments*
;
Ligation
;
Needles
;
Vagina*
7.Acute Bacterial Meningitis after Continuous Epidural Analgesia: A case report.
Mi Sung LEE ; Wha Choon JANG ; Jun Goo RIM
Korean Journal of Anesthesiology 1998;34(6):1258-1262
Recently, continuous epidural catheter insertion is common practice not only in anesthesia but also in pain clinic. Meningitis is rare but serious complication of epidural analgesia. Acute bacterial meningitis occurred in a 82-year-old female patient with thoracic herpes zoster after continuous thoracic epidural analgeia. An MRI of thoracic region did not show an epidural abscess or granulation tissue. Gram stain and culture of the epidural catheter tip and the CSF yielded Staphylococcus aureus. Immediate treatment with antibiotics and supportive therapy was instituted and then the patient discharged without neurologic sequalae.
Aged, 80 and over
;
Analgesia, Epidural*
;
Anesthesia
;
Anti-Bacterial Agents
;
Catheters
;
Epidural Abscess
;
Female
;
Granulation Tissue
;
Herpes Zoster
;
Humans
;
Magnetic Resonance Imaging
;
Meningitis
;
Meningitis, Bacterial*
;
Pain Clinics
;
Staphylococcus aureus
8.The Performance Evaluation of Public Municipal Hospitals: Data Envelopment Analysis and Panel Analysis.
Eun Young CHUNG ; Young Jun SEO ; Hae Jong LEE
Health Policy and Management 2015;25(4):295-306
This study aims to examine the performance of public municipal hospitals through the analysis of data envelopment analysis, efficiency, profitability, and publicness by using panel data during period from 2006 to 2010. The main findings of the study are as follows. First, as a result of efficiency analysis during the period from 2006 to 2010, it was revealed that the number of staff by each job category, labor cost ratio, the number of operating beds need to be decreased. Second, the performance data represented by the indicators of efficiency, profitability and publicness were complementary and showed a tendency of being increased or decreased in same direction. Third, from the result of panel analysis, the efficiency was mainly influenced by the structural factors, while the profitability was influenced by managerial factors, and the publicness by medical environment. In conclusion, in order to enhance the performance of public municipal hospitals in Korea, it is important to harmonize the effort for efficiency, financial and policy support by central and local government, and the continuous participation of community residents.
Hospitals, Municipal*
;
Korea
;
Local Government
10.A Clinical Study of Intussusception in Infancy and Childhood.
Geom Huyn JANG ; Yong Hae LEE ; Jun Taek PARK ; Chang Hee CHOI
Journal of the Korean Pediatric Society 1984;27(5):447-456
No abstract available.
Intussusception*