Most instances of choriocarcinoma of the ovary are gestational in origin. In contrast, nongestational choriocarcinoma of the ovary is an exceedingly rare primary germ cell neoplasm that has worse prognosis than gestational neoplasm. We report a case of pure nongestational choriocarcinoma of the ovary in view of the rarity of its kind. The patient was a 35-year-old Korean unmarried woman who had suffered from vaginal bleeding and feeling of abdominal inflation for two months. The X-ray studies and CT scanning revealed a child head sized cystic mass on the right pelvic cavity and multiple nodular densities in both lung fields and the liver. The mass in pelvic cavity was excised and histologically confirmed to be a nongestational pure choriocarcinoma, arising from the right side ovary.
Child ; Male ; Female ; Humans

Acute generalized exanthematous pustulosis (AGEP) has symptoms of abrupt onset of a widespread pustular eruption on an erythematous. base. Most cases appear to be related to drug reactions, mainly antibiotics, but viral infections and hypersensitivity to mercury may cause AGEP. The essential features of AGEP include. (1) numerous (several dazen) small((5mm), mostly non follicular pustules arising on a widespread erythema:purpura and target-like lesions may be associated; (2) histology showing intraepidermal or subcorneal pustules associated with one or more of the following.clermal edema, vasculitis, perivascular eosinophils, or focal necrosis of keratinocytes; (3) fever (over 38C); (4) neutrophilia, and (5) acute evolution with spontaneous resulotion of pustules within 15 days. We report a case of AGEP which presented with widespread tiny pustules on the whole body except the face, palms and soles. There were petechia, purpura, and vesiculobullous lesions on the axilla, popliteal fossa and upper abdomen. A biopsy specimen from a pustule showed subcorneal pustules with perivascular polymorphous cellular infiltration, marked dermal edema and necrotic keratinocytes. There was complete resolution of the lesions within 10 days.
Abdomen ; Acute Generalized Exanthematous Pustulosis* ; Amoxicillin ; Anti-Bacterial Agents ; Axilla ; Biopsy ; Drug Eruptions ; Edema ; Eosinophils ; Fever ; Hypersensitivity ; Keratinocytes ; Necrosis ; Purpura ; Vasculitis

Sixty-three patients with permanent sigmoid colostomy were surveyed to evaluate their satisfaction and complications with the "irrigation technique" and the "atural evacuation" of the colostomy management (irrigation technique; 32 patients, natural evacuation; 31 patients). All patients had colostomy for at least 12 months without disease recurrence. Each patient was interviewed in addition to standard questionnaire. The irrigation was not associated with any major complication including colonic perforation. The irrigation was used younger age group than the natural evacuation (53+/-10 vs. 62+/-12, P=0.01). The frequency of bowel movement was lower in the irrigation than in the natural evacuation (5.1+/-2.5/wk vs. 10.8+/-9.0/wk, P=0.04). Five patients (16%) of the irrigation experienced spontaneous bowel action but only one patient suffered from it. The time spent for managing irrigation was 59+/-13 minutes. Twenty-three patients (74%) of the natural evacuation suffered from one or moreproblems such as expensive apparatus, leakage, skin irritation or odor. Sixteen patients (52%) of the natural evacuation and 2 patients (6%) of the irrigation were restricted in social activity (P=0.0001). Thirteen patients (42%) of the natural evacuation and 1 patient (3%) of the irrigation were dissatisfied with colostomy management (P=0.002). Thus, the irrigation technique seems to be more effective and satisfactory method for managing colostomy without compromising patient's social activity when it is performed in appropriately selected patients.
Colon ; Colon, Sigmoid ; Colostomy* ; Humans ; Odors ; Surveys and Questionnaires ; Rectal Neoplasms ; Recurrence ; Skin

PURPOSE: The purpose of this study was to describe role conflict and job satisfaction of Neurosurgery Clinical Nurse Specialist(NCNS) and to identify associated factors. METHOD: The target populations was 77 NCNSs from 30 general hospitals. Data were collected with self-administered questionnaires and analyzed using t-test and ANOVA. RESULTS: The overall mean scores of role conflict and job satisfaction were 3.60(+/-0.54) and 3.04(+/-0.46) respectively. Significant variables affecting role conflict were the working period as NCNS, the number of colleague NCNSs in working hospital, and assignment of prescription rights. The significant variable affecting job satisfaction was assignment of prescription rights. There was no statistically significant correlation between job and role conflict. CONCLUSION: The variable effecting both role conflict and job satisfaction was the extent of prescription rights. In order to improve the quality of patient care and to protect Neurosurgery Nurse Clinical Specialist, the enactment of law on prescription practice is needed.
Health Services Needs and Demand ; Hospitals, General ; Human Rights ; Humans ; Job Satisfaction* ; Jurisprudence ; Neurosurgery* ; Nurse Clinicians* ; Patient Care ; Prescriptions ; Specialization ; Surveys and Questionnaires

Acrodermatitis enteropathica(AE) which starts in early infancy after weaning is a rare hereditary chronic disorder of zinc absorption. AE is characterized by alopecia, diarrhea and skin lesions localized to periorificial areas and acrally on the extremities. However, recent reports presented Transient Symptomatic Zinc Deficiency(TSZD) in preterm infants. TSZD is clinically similar to AE and skin lesions rapidly heals after zinc supplementation. When the treatment was withheld, no recurrence was seen. We experienced a TSZD case in a cow's milk fed, preterm infant, so We report it with a brief review of literature.
Absorption ; Acrodermatitis ; Alopecia ; Diarrhea ; Extremities ; Humans ; Infant* ; Infant, Newborn ; Infant, Premature* ; Milk* ; Recurrence ; Skin ; Weaning ; Zinc*

No abstract available.

No abstract available.
Breast Feeding* ; Breast* ; Iron*

BACKGROUND: Until the recent development of the Q-switched lasers, it was impossible to remove tattoos without causing scarring and sometimes disfiguring. Variations in wavelengths and pulse widths may result in different clinical effects or risks. OBJECTIVE: The purpose of this study was to investigate the therapeutic effects of the alexandrite laser in removing tattoos clinically, histologically and ultrastructually. METHODS: Fourty-two patients with gray, black, and blue-black colored tattoos were treated with fluences ranging from 6.5 to 8.0 J/cm2 at a minimal interval of 6 weeks. We took pictures of each tattoo prior to treatment and each treatment session in order to evaluate clinical irnprovement. Biopsy specimens were obtained from 8 patients, on prearranged times: before, immediately after, one week after and 6 weeks after irradiation. RESULTS: The results if the treatment of 42 patients with tattoos were analyzed. After two treatment sessions, 89% of patients showed 51% to 95% improvement. Transient hyperpigmentation and hypopigmentation occurred in 7 patients. However, skin atrophy, hypertrophic scar or infection did not occur. Ir a biopsy specimen taken 6 weeks after irradiation on light microscopy, most of tattoo granules disappeared without collagen fiber change. However, macrophage engulfing tattoo granules and a minute amount of tattoo granules still remained in the dermis on electron microscopy. CONCLUSION: The .alexandrite laser is considered to be a safe and effective treatment rnodality for removal of gray, black, and blue-black tattoo pigments.
Atrophy ; Biopsy ; Cicatrix ; Cicatrix, Hypertrophic ; Collagen ; Dermis ; Humans ; Hyperpigmentation ; Hypopigmentation ; Lasers, Solid-State* ; Macrophages ; Microscopy ; Microscopy, Electron ; Skin

As the breast is a symbol of feminity, so nipple areolar complex is a crucial aesthetic unit of the breast. Symmertrical and appropriate nipple areolar complex completes the breast reconstruction. Throughout the history of breast reconstruction, various methods of nipple areolar reconstruction have been developed. Composite graft and several local flap methods have been used for reconstruction of nipples. Skin grafts from contralateral areolar or inguinal area and tattooing methods have been introduced for areolar reconstruction. Among 85 patients of breast reconstruction during recent three years, we experienced only 14 cases of nipple areolar reconstruction. This fact is partly from conservative attitude of Korean women to breast reconstruction and also from the long time-period needed to accomplish an acceptable breast mound. For nipple reconstrction, we performed eight H-shape local flaps, three fish tail shape local flaps, and three composite grafts. For reconstruction of areola, full thickness skin graft was used in 13 cases(10 from inguinal area, 3 from contralateral areola) and tattooing was used in a case. We experienced necrosis of reconstruction nipple in two cases(one in fish tail shape local flap cases and one in composite graft cases). There was no other remarkable complication. Among the three methods of nipple reconstruction. H-shape local flap method was a reliable one which provides stable nipple projection as well as simplicity. In most cases areola was successefully reconstructed with full thickness skin graft and if the size of contralateral areola is large enough to share, contralateral areolar sharing seems to be the best choice. In conclusion, the combination of a H-shape local flap and a full thickness skin graft from the inguinal area provides a satisfactory projection of the nipple and pigmentation of the nipple and pigmentation of the areola comparable to the other side.
Breast ; Female ; Humans ; Mammaplasty ; Necrosis ; Nipples* ; Pigmentation ; Skin ; Tattooing ; Transplants

Diabetes mellitus is a chronic disease that requires continuous self-management to prevent complications. Diet therapy is essential for the treatment of diabetes mellitus, and proper nutrition education should be provided to patients so that changes in eating habits and lifestyle can be induced. This review examines the current status and effects of nutrition education programs for diabetic patients in Korea.
Chronic Disease ; Diabetes Mellitus ; Diet Therapy ; Eating ; Education* ; Humans ; Korea* ; Life Style ; Self Care