To establish new criteria to determine the depth of bladder cancer as well as to obtain the findings of each stage of bladder cancer we reviewed high resolution MR images of 18 bladder cancer patients including seven cases (26%) with superficial bladde4r wall invasion. All MR scans were done before biopsy or surgery. Multiple layers of the bladder wall (inner black, middle white, outer black) were demonstrated in 11 cases out of a total 18 cases. Thickening of the middle layer caused by tumor infiltration or edema of lamina propria was seen in 8 of 12 patients with stage T2 or greater, and was suggestive of superficial muscle invasion when multiple layers were demonstrated. Disruption of outer layer (as well as inner layer) and external protrusion of tumor itself were indicative of perivesical invasion. When multiple layers were not demonstrated, the depth of tumor invasion could not be judged. High resolution MR imaging can depict submucosal invasion, muscle invasion, and perivesical invasion secondary to bladder cancer.
Biopsy ; Edema ; Humans ; Magnetic Resonance Imaging* ; Mucous Membrane ; Urinary Bladder Neoplasms* ; Urinary Bladder*

Behcet's disease, though originally described as a triad of oral and genital aphthous ulcers and inflammatory, occular lesion, has had several new elements added to its description. The gastrointestinal manifestation of Behcet's disease including colitis and esophageal ulceration has been recognized in recent years. Four cases of Behcet's disease with colitis and one case with esophageal ulceration are presented and characteristic radiographic findings are described. In colitis and ulcerative esophagitis in Behcet's disease, the ulcers show collar-button appearance and tend to perforate at multiple sites, producing panperitonitis and esophagobronchial fistula, and intervening mucosa is usually normal.
Colitis ; Esophagitis ; Fistula ; Mucous Membrane ; Stomatitis, Aphthous ; Ulcer

A retrospective quality assurance study of intraoperative consultation (frozen section) was carried out to assess the accuracy and to determine the reasons of discordance. Of 14,977 surgical pathology cases accessioned over a 6-month period in Asan Medical Center, frozen sections were done on 1,270 (8.5%) patients and 2,392 frozen sections (1.88 frozen sections/case) were performed. Discordance was noted in 106 cases (4.4%) and diagnosis was deferred in 26 cases (1.1%). All deferred cases were reviewed with the result of 53.8% justified and 46.2% unjustified. The discordant cases were divided into three categories as to their clinical significances: category A (no affect on patient care) 61.3%, B (minimal affect) 9.4%, and C (major affect) 29.2%. Of 31 category C cases, 7 cases were false positive and 24 cases were false negative. Misinterpretation (70.8%) was the leading cause of discordance, followed by sampling error (15.1%), failure to identify lesion (8.5%), and technical problem (5.7%). More than one-third (35.8%) of all discordances were of central nervous system cases. Total central nervous system cases were 403 (16.8%) with a significantly higher disordance rate (9.8%) and deferral rate (2.5%) in comparison to the other cases with 3.4% discordance rate and 0.8% deferral rate. There were 43 colorectal cancer cases of intraoperative consultation for adequacy of resectional margins. The surgical margins were between 0.4 cm and 28 cm (mean: 6.7 cm) away from the tumor and there was no tumor-positive case. The study indicates surgical pathology should 1) promote interpretative skills in cases involving minute fragments of neurosurgical cases, 2) defer the diagnosis and ask for more tissue on inadequate or inappropriate specimens and 3) give only gross opinions without unnecessary frozen section procedures in the event of simple, clear-cut cases.
Abscess ; Anti-Bacterial Agents ; Biopsy ; Central Nervous System ; Chungcheongnam-do ; Colitis, Ulcerative ; Colorectal Neoplasms ; Diagnosis ; Diagnosis, Differential ; Endoscopy ; Enterocolitis, Pseudomembranous* ; Frozen Sections* ; Humans ; Mucous Membrane ; Necrosis ; Pathology ; Pathology, Surgical ; Retrospective Studies ; Selection Bias

Although causative factors are not completely defined, carcinogenesis of colorectal cancer is attributed to multiple genetic alterations. The abnormal expressions of oncogenes are regarded to be responsible for the production of malignant phenotype, subsequent invasion and metastasis. From 63 surgically resectable colorectal adenocarcinoma patients, expression of oncogenes in colorectal cancer tissue was evaluated with immunohistochemical staining methods using monoclonal antibodies to products of the oncogenes. To evaluate the possibility of oncogenes as a prognostic factor, we studied the relationship between the expression of oncogenes and the clinicopathologic findings which are well known prognostic factors. Rates of expression in colorectal cancer tissue were 27% for c-myc, 74.6% for c-Ha-ras and 77.8% for c-erbB-2 oncogenes. The positive rate of c-erbB-2 oncogene was higher in the well differentiated group than in the poorly differentiated group. The rates of expression of c-myc and c-Ha-ras oncogenes were significantly correlated each other. Expression of these oncogenes in colorectal cancer were not correlated with the pathologic stage, location of cancer, DNA ploidy pattern and histologic differentiation except between c-erbB-2 and histologic differentiation. In conclusion, there seems to be a possibility that c-erbB-2 could be used as a prognostic factor of colorectal cancer. However, further and more intensive study seems to be required.
Adenocarcinoma ; Antibodies, Monoclonal ; Carcinogenesis ; Colorectal Neoplasms* ; DNA ; Humans ; Neoplasm Metastasis ; Oncogenes* ; Phenotype ; Ploidies

No abstract available.
Abstracting and Indexing as Topic/standards ; *Editorial Policies ; *Guidelines as Topic ; Humans ; Korea ; Linguistics ; Manuals as Topic ; Nursing Research/*standards ; Peer Review, Research ; Periodicals as Topic/*standards ; Research Design/standards ; Societies, Scientific ; Translating ; Writing/*standards

The history of rehabilitation of disabilities in Korea began with the foreigners and missionaries who were interested in it after Korean War. In 1981. Disabled Persons Welfare Act was enacted and the 88 Paralympics brought the nations attention to the welfare and rehabilitation of persons with disabilities. Since then, the facilities and the services for the disabled persons have expanded rapidly and the rehabilitation treatment and nursing intervention are drawing more attention. Against this background, the survey on the current status of disabilities, welfare service, facilities, and rehabilitation nursing was conducted. The results of this survey are as follows 1. According to the 2000 census of disabilities. the number of persons with disabilities in Korea is estimated at 1.449.500. or 3.09% of the entire Korean population, 0.74% up from 2.35% in 1995. 2. Disability Types in 2000 The 2000 census showed that the persons with disabilities numbered 1.449, 496 out of the total population and 1.024,371 persons are registered for disability. making up 70.7% of the estimated disabled population. Among them, physically disabled persons accounted for the largest 41. 7% (605.127) and mentally retarded persons stood at the smallest 9% (13.481). 3. Percentage of Disability Presence The survey showed that more than 90% of disability were acquired. However, 44.8% of mental disability and 61.4% of hearing /speaking disability were not acquired after birth. This means that these disabilities happened by congenital cause or birth accident. 4. Yearly Figure of Registered Disabled Persons In 1989. 218,601 persons registered for disability and, in 2000, the number increased by 4.7 times to 1.024.371. These figures are different from the actual number of disabled persons. According to the 1995 census. 1.053.486 were disabled persons but only 378,323 registered for disability. And. in the 2000 census. 1.024,371 out of the 1.449.496 of disabled persons registered for disability. 5. Welfare Service for Persons with Disability 62.6% of the total disabled people are registered and physically disabled persons accounted for the highest percentage of 96.7%. 26.5% of non-registered disabled people said that they didn't know the registration procedure. The rest of them replied that they didn't think they were disabled or that registration didn't seem to give any benefits 6. Welfare Policies for Disabled Persons The welfare benefits given to the disabled are as follows: Issuance of disabled sign for car drivers. Permission to use LPG fuel. Reduction of public facility fees. Household allowance. Tax reduction or exemption, Medical allowance and education subsidy for children, and Housing. 7. Current Condition of Welfare Facilities by Disability Type. The welfare institutions for disabilities numbered 188i in total and they can accommodate 16,823 persons. Categories of these institutions are physical disability(37), visual disability(10). hearing/speaking disability(l4). mental retardation(59), and sanatoriums(68). 6. Human Resource of Rehabilitation of Disabilities Advanced education programs include rehabilitation nursing in its curriculum and this was selected as the program of Korean Academic Society of Nursing in 1990. In November 1997, Korean Academic Society of Rehabilitation Nursing was launched and many academic meeting and seminars were held. This organization is also making efforts to develop the education program for qualified rehabilitation nursing professionals and to develop the standards of rehabilitation nursing practice. In the professionals of the rehabilitation there are rehabilitation specialist, physical therapist, speech therapist, occupational therapist. It is needed to come up with the measures to supply stable human resources following the demand of disabled persons and to recognize the private certificates for rehabilitation professionals as official ones after reviewing the education and training programs of private institutions. 9. Rehabilitation Nursing 1) Rehabilitation nursing was taught as an independent subject in 11 undergraduate programs and 9 graduate programs. 2) Research on rehabilitation nursing in Korea were 24 experimental research and 11 non-experimental research. The intervention of experimental research were mostly education and exercise rehabilitation programs. 3) In the three rehabilitation hospitals, nursmg IS divided into two categories, direct nursing and education & counseling. Direct nursing includes tracheostomy or nasogastric tube care, urination and defication, skin care, pain control, complication, prevention and care, prevention of injury from a fall. etc.
Censuses ; Child ; Counseling ; Curriculum ; Disabled Persons ; Education ; Emigrants and Immigrants ; Family Characteristics ; Fees and Charges ; Hearing ; Housing ; Humans ; Korea* ; Korean War ; Mentally Disabled Persons ; Missions and Missionaries ; Nursing ; Parturition ; Penicillin G Benzathine ; Physical Therapists ; Public Facilities ; Rehabilitation Nursing* ; Rehabilitation* ; Skin Care ; Specialization ; Taxes ; Tracheostomy ; Urination

CT is a highly accurate method of detecting and clarifying the narure of space-occupying lesions within theliver nd pancreatic disease. It was found to be a reliable, non invasive method for detecting the lesion. A normalrange of attenuation values were obtained from 71 CT examinations of the upper abdomen, that is liver, spleen,pancreas, aorta, before and after contrast enhancement in whom no radiologic or laboratory abnormality of theseorgans were detected from March to Sept. 1983. The results were as follows; 1. The age distribution was from 28years to 71 years. The sex ratio was 45 male to 26 female. 2. Mean Hounsfield Units (HU) in liver before contrastenhancement and after contrast enhancement liminute, 3 minutes, 5 minutes, 10 minutes were 56.1±3.85, 75.0±4.77,82.0±3.71, 84.3±2.76 and 88.2±3.95 HU respectively. 3. Mean Hounsfield Units in pancreas before contrastenhancement and after contrast enhancement 1 minute, 3 minutes, 5 minutes, 10 minutes were 43.0±4.30, 66.5±4.27,71.2±2.39, 74.4±3.00 and 79.2±2.(0 HU respectively. 4. Mean Hounsfield Units in spleen before contrastenhancement and after contrast enhancement 1 minute, 3 minutes, 5 minutes 10 minutes were 53.0±4.31, 71.4±2.84,75.3±2.70, 80.5±3.04 and 83.2±2.14 HU respectively. 5. Mean Housfield Units in aorta before contrastenhancement and after contrast enhancement 1 minute, 3 minutes, 5 minutes 10 minutes were 45.1±5.39, 86.7±6.86,92.5±5.33, 106.8±4.12 and 114.1±5.02 HU respectively. 6. The most significant finding was that the livernormaly had the highest attenuation values of any of the organs measured. When another viscera in upper abdomenhad a attenuation value greater than that of the liver, this reflected abnormal lesions.
Abdomen ; Age Distribution ; Aorta ; Female ; Humans ; Liver ; Male ; Methods ; Pancreas ; Pancreatic Diseases ; Sex Ratio ; Spleen ; Viscera

Eleven magnetic resonance(MR) and CT imagings were performed in nine patients with mild to moderate degree oddelayed neuropsychiatric symptoms following acute carbon monoxide(CO) poisoning, to evaluate the capability of MRin demonstrating any additional finding to CT. The MR images were obtained using 0.15 Tesla resistive system withvariuos combination of three pulse sequences, including partial saturation recovery, T2-weighted spine echo andinversion recovery. Bilateral white matter abnormalities suggesting demyelination were demonstrated in 4 patientswith MR and in only 2 patients wtih CT. The contrast discrimination between normal and abnormal white matterproved to be better with T2-wieghted spin echo and inversion recovery than with partial saturation recovery andCT. But necrosis of the globus pallidus(1 patient) and diffuse atrophy(3 patients) were equally demonstrated onboth MR and CT. It is suggested that MR be used as a initial imaging method in the evaluation of the delayedencephalopathy following acute CO poisoning, especially for the detection of the possible white matter lesions.
Brain Diseases ; Carbon Monoxide Poisoning ; Carbon Monoxide ; Carbon ; Demyelinating Diseases ; Discrimination (Psychology) ; Humans ; Methods ; Necrosis ; Poisoning ; Spine ; White Matter

Situs inversus totalis is a mirror image of the normal anatomy in the thoracic and the abdominal cavity. The cardiac apex, the stomach and the aortic arch are all on the right side. It is a rare condition with a genetic predisposition that is autosomal recessive and is associated with a 5-10% incidence of congenital heart disease. In a situs inversus totalis with cholelithiasis and choledocholithiasis, laparoscopic cholecystectomy was performed three days after endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy. In the laparoscopic cholecystectomy, pneumoperitoneum was made by a closed method, and the cholecystectomy was performed using the three trocar technique. Although we should pay much attention to the details of left-right reversal, these techniques can be safely and effectively applied to situs inversus totalis patients.
Abdominal Cavity ; Aorta, Thoracic ; Cholangiopancreatography, Endoscopic Retrograde* ; Cholecystectomy ; Cholecystectomy, Laparoscopic* ; Choledocholithiasis ; Cholelithiasis ; Female ; Gallstones ; Genetic Predisposition to Disease ; Heart Defects, Congenital ; Humans ; Incidence ; Pneumoperitoneum ; Situs Inversus* ; Stomach ; Surgical Instruments

Intussusception is rare in adult and usually caused by organic lesions, although there is a singnificant numbeof so-called idiopathic cases. The diagnosis of intussusception have been made by pali abdomen, barium enema andsmall bowel series. But recently ultrasound and CT make a contribution to diagnose intussusception. CT is not theprimary means for evaluation a gastrointestinal tract abnormality but also provides yaluable informations inevaluating disorders affecting the hollow viscera of the alimentary tract. CT image of intussusception demonstratea whirl like pattern of bowel loops separated by fatty stripe correlating to the intestinal walls. Abdominal ultrasonogram was used as the initial diagnostic test in 2 cases out of total 4 cases, with abdominal mass ofunknown cause. It revealed a typical pattern, composed of a round or oval mass with central dense echoes andperipheral poor echoes. We report 4 all cases of intussusception in adult who were performed by CT and/orultrasound. All cases were correlated with barium enema examination and/or surgical reports.
Abdomen ; Adult ; Barium ; Diagnosis ; Diagnostic Tests, Routine ; Enema ; Gastrointestinal Tract ; Humans ; Intussusception ; Ultrasonography ; Viscera