This study was undertaken to clarify whether the color changes of skin in summer are remarkable or not. The skin color of abdomen, extensor and flexor of forearm, forehead, and cheek were measured in 27 health male students who had never tanned their skin intentionally during this experiment with Color and Color Difference Meter(Nippon Denshoku Kogyo Ca. CP6R 1001-DP) which represents skin color as 'L', 'a', and 'b' values. The 'L', 'a', and 'b' values mean the degree of lightness, redness, and yellowness respectively. Measurements had been performed four times repeatedly from summer(june) to auturmn(October) with intervals of 6 weeks. The obtained values were evaluated with statistical method, and the results were sumrnarized as follows: l. Abdominal skin showed no significant color changes in this experiment. 2 Extensor and flexor skin of forearm showed significant decrease in lightness from July, and the degree of decrease was more remarkable on extensor skin than on flexor skin. The lighteness had not been recovered by October on extensor skin and by September on flexor skin. There was no significant change in redness and yellowness on both places in this experiment. 3. Forehead skin showed no significant change in lightness and yellowness in this experiment, and showed transient decrease in redness in July. 4. Cheek skin showed no significant change in lighteness and redness in this experiment, and showed transient increase in yellowness in October.
Abdomen ; Cheek ; Forearm ; Forehead ; Humans ; Intention ; Male* ; Skin* ; Triacetoneamine-N-Oxyl

Acinic cell tumor, a rare tumor of the salivary gland origin, consists of cells similar to the serous cells of the salivary gland. The tumor is almost exclusively paroti4 gland origin, accounting for 2. 7 to 4. 0% of all parotid tumors. The tumor is not,benign but has at least a low-grade malignant potential. We described herein a case of acinic cell tumor which had occurred on an unusual site, right inner epicanthal area of a 9-year-old girl Microscopically, a hematoxylin-eosin stained biopsy specimen showed rnany lobules com of round or polyhedral tumor cells. Each tumor cell had distinct cell membrane, clear cytoplasm, and relative1y eccentric nucleus. The cytoplasm of tumor cell cantaine4 diastase resistant PAS-positive material.
Acinar Cells* ; Amylases ; Biopsy ; Carcinoma, Acinar Cell* ; Cell Membrane ; Child ; Cytoplasm ; Female ; Humans ; Salivary Glands

No abstract available.
Dermatitis*

Eccrine spiradenoma is clinically characterized by a solitary, movable, tender noduie occurring most frequently on the ventral surfase of the upper body. A striking symptom is paroxysmal pain. Histopathologically, the encapsulated lobules of the tumor are composed of masses of basophilic cells, usually arranged in whorls, cords, and pseudogland.s. Within the whorls and pseudoglands, two types of celIs are notedperipheral intensely staining cells and central pale-staining cells. We describe herein a patient with an indolent eccrine spiradenoma, which had been diagnosed histopathologically.
Basophils ; Humans ; Strikes, Employee

Serologic tests for syphilis including VDRLand FTA-ABS tests have been carried out in 2,753 VISA applicants for emigration, 8, 501 blood donors and 2, 588 pregnant women from January to December 1981. We have also been observing biologic false positive rate in 759 VDRL-reactive persons among those tested for STS in Severance Hospital in the year 1981, All the above subjects were twenty years old or over. The results are summarized as follows: l. I 2, 753 VISA applicants, VDRL test showed postive in 42 applicants (l. 5 %). Of these 42 applicants, 37(1. 3%) had a rmotie FTA ABS test. 2. In 8,501 blood donors, the reactive rate for the VLRL test was 1.0pk. 3. ln 2, 588 pregnent women, the VDRL test showed gositive in 20 women (0.8%). Of these 20 women, l8(0.7%) had a reactive FTA-ABS test. 4. The cuantitative test of VL'RL resulted in low titer below 1: 4 in 97. 6% of VDRL-reactive VISA applicants and in 85. 0% of VLRL-reactive pregnant women, 5. The overall biologic false positive rate was 8. 7/o in 759 VDRL-reactive persons amorg those tested for STS in Severance Hospital in time year l98l, using the FTA-ABS test as the standard. In particular, it was higher, namely l7. 0/a, in 32 persons who were wezkly reactive to the VDRL test. From the results it is clear that the prevalence of syphilis is gradually decreasing recently compared to the mid 1970 s.
Blood Donors ; Emigration and Immigration ; Female ; Fluorescent Treponemal Antibody-Absorption Test ; Humans ; Korea* ; Pregnant Women ; Prevalence* ; Serologic Tests ; Syphilis*

Eruptive neonatal hemangiomatosis is an uncommon disorder, which is divided into two types according to the extent of involvement: Benign type with cutaneous hemangiomatosis only and diffuse type with widespread hemangiomas of skin and viscera. The organs commonly affected are the gastrointestinal tract, brain, liver and lung. The Diffuse type is often fatal. We herein report a case of eruptive neonatal hemangtomatosis with cutaneous and hepatic involvement. The size of the hepatic arteriovenous malformation was markedly decreased after 2 months' therapy with oral prednisolone.
Arteriovenous Malformations ; Brain ; Gastrointestinal Tract ; Hemangioma ; Liver ; Lung ; Prednisolone ; Skin ; Viscera

Sixty-five volunteers whose skin had never been tanned intentionally participated in this experiment. The skin colors of extensor and flexor of forearm, fore-head, and cheek were measured with Color and Color Difference Meter(Nippon Denshoku Kogyo Co. CP6R 1001-DP) which represents .kin color as 'L, a, and b in values. The L, a', and b values mean the degree of ligntness, redness, and yellowness respectively. Measurement has been performed seven times repeatedly in a year at regular intervals. From the study, the following results were obtained. ]'lexor skin of forearm showed the highest lightness in a year compared to the other regions. All of the regions examined showed the highest lightness in spring compared to the other seasons. 3. Cheek skin showed the highest redness among the four checked regions in a year. 4, All of the checked regions showed the higher redness in summer than in spring. and autumn. 5 All of the checked regions showed the lowest yellowness in May.
Cheek ; Female ; Forearm ; Humans ; Intention ; Seasons* ; Skin* ; Triacetoneamine-N-Oxyl ; Volunteers

A 18-month-old girl was seen because of an yellowish brown papular eruptions on the face, earlobes and neck of one year duration. A skin biopsy specimen revealed circumscribed cellular infiltrates composed of predorninantly pleornorphic histiocytes. Electron microscopy of biopsy material disclosed numerous worm like particles and coated vescles in limited area of the cell cytoplasm, consistent with the findinga described in benign cephalic histiocytosis. After six months of her first visit, the individual papules became flattened.
Biopsy ; Coated Vesicles ; Cytoplasm ; Female ; Histiocytes ; Histiocytosis* ; Humans ; Infant ; Microscopy, Electron ; Neck ; Skin

Contact hypersensitivity (CH) responsiveness to 24-dinitro-l-fluorobenzene(DNFB)is depressed in mice sensitized through unexposed skin sites after exposure to high dose of ultraviolet B radiation(UVB). Exposure of mice to ultraviolet A(UVA) radiation in combination with 8-methoxypsoralen(8-MOP) also results in a systemic suppression of CH. Our study was designed to determine whether a high dose of UVA radiation alone can induce a systemic suppression of CH, and if so, which phase of CH response is influenced by UVA radiation. Relatively large doses of UVA(400, 600, 800J/cm²) induced significant systemic suppression of CH when DNFB was applied to UVA-unirradiated abdominal skin. The duration of the rest period after UVA exposure did not cause any significant change in systemic suppresion of CH. Functional analyses showed that lymph node cells(LNCs) obtained from donors that were sensitized on the unirradiated skin site with DNFB 5 days after UVA treatment transferred normal ear-swelling responsiveness to non-primed recipients, thus implying that high doses of UVA can induce systemic suppression which is not affected in the induction phase of CH but affected in the elicitation phase of CH. UVA irradiation de-creased Langerhans cell(LC) numbers significantly with a dose of 100J/cm² or greater. LNCs obtained from donors that were sensitized on the irradiated skin site with DNFB 5 days after UVA treatment did not transfer normal ear-swelling responsiveness to non-primed recipients. This phenomenon may be related to the decreased number of LC after UV treatment. To look for possible mediators impairing the elicitation phase of the CH reaction, we checked prostaglandin E(PGE) levels in serum after 800J/cm² irradiation. A high dose of UVA did not increase the serum PGE level in mice as much as UVB irradiation, in which a significant increase of PGE may affect CH response.
Animals ; Dermatitis, Contact* ; Dinitrofluorobenzene ; Humans ; Lymph Nodes ; Mice ; Prostaglandins E ; Skin ; Tissue Donors

Contact hypersensitivity (CH) responsiveness to 24-dinitro-l-fluorobenzene(DNFB)is depressed in mice sensitized through unexposed skin sites after exposure to high dose of ultraviolet B radiation(UVB). Exposure of mice to ultraviolet A(UVA) radiation in combination with 8-methoxypsoralen(8-MOP) also results in a systemic suppression of CH. Our study was designed to determine whether a high dose of UVA radiation alone can induce a systemic suppression of CH, and if so, which phase of CH response is influenced by UVA radiation. Relatively large doses of UVA(400, 600, 800J/cm²) induced significant systemic suppression of CH when DNFB was applied to UVA-unirradiated abdominal skin. The duration of the rest period after UVA exposure did not cause any significant change in systemic suppresion of CH. Functional analyses showed that lymph node cells(LNCs) obtained from donors that were sensitized on the unirradiated skin site with DNFB 5 days after UVA treatment transferred normal ear-swelling responsiveness to non-primed recipients, thus implying that high doses of UVA can induce systemic suppression which is not affected in the induction phase of CH but affected in the elicitation phase of CH. UVA irradiation de-creased Langerhans cell(LC) numbers significantly with a dose of 100J/cm² or greater. LNCs obtained from donors that were sensitized on the irradiated skin site with DNFB 5 days after UVA treatment did not transfer normal ear-swelling responsiveness to non-primed recipients. This phenomenon may be related to the decreased number of LC after UV treatment. To look for possible mediators impairing the elicitation phase of the CH reaction, we checked prostaglandin E(PGE) levels in serum after 800J/cm² irradiation. A high dose of UVA did not increase the serum PGE level in mice as much as UVB irradiation, in which a significant increase of PGE may affect CH response.
Animals ; Dermatitis, Contact* ; Dinitrofluorobenzene ; Humans ; Lymph Nodes ; Mice ; Prostaglandins E ; Skin ; Tissue Donors