A rare case of chondrosarcoma of the skull in a 57 year old female is reported. The tumor was located in the right parasella region, extra-dural type. A plain skull showed amorphous calcific densities in the right parasella area. Right carotid angiogram showed a slightly opening of carotid siphon on lateral view. CT brain scan showed a irregular mottled calcific density in the right parasella area. Osteoplastic craniotomy on right frontotemporal area was performed for removal of tumor. Then, patient was improved markedly.
Brain ; Chondrosarcoma* ; Craniotomy ; Female ; Humans ; Middle Aged ; Oculomotor Nerve Diseases ; Skull

A rare case of chondrosarcoma of the skull in a 57 year old female is reported. The tumor was located in the right parasella region, extra-dural type. A plain skull showed amorphous calcific densities in the right parasella area. Right carotid angiogram showed a slightly opening of carotid siphon on lateral view. CT brain scan showed a irregular mottled calcific density in the right parasella area. Osteoplastic craniotomy on right frontotemporal area was performed for removal of tumor. Then, patient was improved markedly.
Brain ; Chondrosarcoma* ; Craniotomy ; Female ; Humans ; Middle Aged ; Oculomotor Nerve Diseases ; Skull

The posterior lumbar interbody fusion not only has the advantage of avoiding collapse of the motion segment, it also accomplishes wide decompression of all neural components and distraction of the interverteral disc space. The modified technique of posterior lumbar interbody fusion with preservation of facet and cortical plate alleviates postoperative slippage and settlement. And also, modern improvements in operative illumination, better control of epidural hemorrhage by proper positioning of the patient, and the use of Surgicel as a tamponade in retracting epidural veins and dura definitely improve the technical feasibility of PLIF. Recently we encountered 3 cases of PLIF and the postoperative results were excellent.
Decompression ; Hemorrhage ; Humans ; Lighting ; Low Back Pain ; Veins

BACKGROUND: Although post operative pain has been reduced significantly since the advent of laparoscopic surgery, many patients still complain of moderate abdominal and shoulder pain after surgery. METHOD: Patients scheduled for elective laparoscopic cholecystectomy were assigned to three groups by simple randomization(12 patients per group). Group I patients(control) had no specific treatment, group II patients had 10 ml of normal saline instillation, and group III patients had 10 ml of 0.5% bupivacaine instillation. Instillation was made directly into the gallbladder bed and right subdiaphragmatic space under direct vision by the surgeon at the end of the procedure and before evacuating the pneumoperitoneum. RESULT: Compared to that of the group I, VAS of group II and III did not show any statistically significant difference. Compared to the group I, group II & III showed no significant difference in numbers of requests of Tiaprofenic acid during the 36hours after the surgery. CONCLUSION: Topical instillation of 0.5% bupivacaine 10 ml to the gallbladder bed and right subdiaphragmatic space after laparoscopic cholecystectomy is not effective for the post operative pain control.
Bupivacaine* ; Cholecystectomy, Laparoscopic* ; Gallbladder ; Humans ; Laparoscopy ; Pain, Postoperative* ; Pneumoperitoneum ; Shoulder Pain

Intracranial tuberculoma may imitate, both clinically and radiologically, the more commonly observed intracranial tumors. A 16 year old female patient was admitted due to exophthalmus(o.d) and headache. Neurologically papilledema was noted on the both fundus and exophthalmometry revealed that exophthalmus(17mm, 13mm). CT brain scan showed slightly high density lesion with surrounding low density in right frontotemporal area, attached to the sphenoid bone. And also hyperostosis was noted at the right sphenoid bone and dense homogeneous enhancement of mass after contrast infusion was seen. This case reports outlines the development of such a lesion masquerading as a typical meningioma of the sphenoid ridge. Discussion of intracranial tuberculoma follows, with special reference to clinical and radiological findings.
Adolescent ; Brain ; Female ; Headache ; Humans ; Hyperostosis ; Intracranial Pressure ; Meningioma* ; Papilledema ; Sphenoid Bone ; Tuberculoma* ; Tuberculoma, Intracranial

Parkinsonism is a clinical syndrome presenting with bradykinesia, tremor, rigidity, and postural instability. Nonmotor symptoms have recently been included in the parkinsonian syndrome, which was traditionally associated with motor symptoms only. Various pathologically distinct and unrelated diseases have the same clinical manifestations as parkinsonism or parkinsonian syndrome. The etiologies of parkinsonism are classified as neurodegenerative diseases related to the accumulation of toxic protein molecules or diseases that are not neurodegenerative. The former class includes Parkinson’s disease (PD), multiple-system atrophy, progressive supranuclear palsy, and corticobasal degeneration. Over the past decade, clinical diagnostic criteria have been validated and updated to improve the accuracy of diagnosing these diseases. The latter class of disorders unrelated to neurodegenerative diseases are classified as secondary parkinsonism, and include drug-induced parkinsonism (DIP), vascular parkinsonism, and idiopathic normal-pressure hydrocephalus (iNPH). DIP and iNPH are regarded as reversible and treatable forms of parkinsonism. However, studies have suggested that the absence of protein accumulation in the nervous system as well as managing the underlying causes do not guarantee recovery. Here we review the differential diagnosis of PD and parkinsonism, mainly focusing on the clinical aspects. In addition, we describe recent updates to the clinical criteria of various disorders sharing clinical symptoms with parkinsonism.

No abstract available.
Ilizarov Technique*

No abstract available.
Hemolytic-Uremic Syndrome* ; Postpartum Period*

BACKGROUND: Age-related differences in response to pain stimuli remain a controversial issue. The purpose of this study was to evaluate the effect of age on pain response using the formalin treated rats and streptozotocin-induced diabetic rats tested for mechnical, cold allodynia and thermal hyperalgesia. METHODS: We divided Sprague-Dawley rats into 3 groups by age, 5 weeks old (n = 10), 8 weeks old (n = 10), 12 weeks old (n = 10). Each group was divided into 2 subgroups (n = 5). One was formalin tested and the other was injected with streptozotocin 75 mg intraperitoneally for succesive two days. On the 3rd day after injection, we examined mechnical allodynia using a von Frey filament, and tested thermal hyperalgesia using a tail immersion test in 50degrees C or 5degrees C water. RESULTS: In the formalin test, pain response was higher in the younger age group (P < 0.05) in phase 2. In the streptozotocin-induced diabetic rats, no difference in mechanical allodynia was observed between the subgroups. In the 50degrees C water thermal hyperalgesia test, withdrawal latency decreased in each group after streptozotocin injection (P < 0.05) and 5-week animals had a lower withdrawal latency than the 12-week animals (P <0.05). In the 5degrees C water cold allodynia test, the 5-week animals showed a lower withdrawal latency than the other age groups (P < 0.05). CONCLUSIONS: In this study, the effect of age on the response to a pain stimulus depends upon the stimulus. This is important when designing the pain models. The mechnisms involved require further investigation.
Animals ; Formaldehyde ; Humans ; Hyperalgesia ; Immersion ; Pain Measurement ; Rats* ; Rats, Sprague-Dawley ; Streptozocin ; Water

The ORF5 gene encodes a major envelope glycoprotein (GP5), which is one of the three major proteins of porcine reproductive and respiratory syndrome virus (PRRSV). The GP5 protein has been known to be a 24.5-26kDa N-glycosylated envelope protein. The GP5 is involved in inducing neutralizing antibodies. For this reason, the GP5 is primary candidate for the PRRSV subunit vaccine. To produce the native form of GP5 in mammalian cells, we have cloned the ORF5 gene from PRRSV CNV-1 into the Semliki Forest virus (SFV)-based expression vector, resulting in recombinant pSFV-ORF5. By the infection with recombinant pSFV-ORF5 to BHK-21 cells, the GP5 expression was confirmed by immunocytochemistry and immunoblotting assay. The recombinant virus particle harboring ORF5 gene was infectious to BHK-21 and MARC-145. The RNA synthesis and expression of GP5 in the infected cell was also confirmed by RT-PCR.
Animals ; Base Sequence ; DNA Primers ; *Genes, Viral ; Plasmids/genetics ; Porcine respiratory and reproductive syndrome virus/*genetics ; Restriction Mapping ; Reverse Transcriptase Polymerase Chain Reaction ; Semliki forest virus/*genetics ; Swine ; Viral Envelope Proteins/genetics ; Viral Proteins/*genetics ; Virology/methods