1.Polymers in the Cardiovascular System.
Journal of the Korean Medical Association 1997;40(4):444-450
No abstract available.
Cardiovascular System*
;
Polymers*
2.Effects of Alcohol Administration on Cytokines, Nitric Oxide, Infection Anaphylaxis and Melanoma Growth.
Tai You HA ; Hyun Ju HA ; Young Hyun KIM
Korean Journal of Immunology 1997;19(4):583-594
The present study was undertaken to investigate the effect of ethanol administration on the resistance of mice to Cryptococcus neoformans, IL-2 production of murine splenocytes, active systemic anaphylaxis induced by ovalbumin (OVA), serum TNF-alpha production, nitric oxide (NO) production by peritoneal machrophages and B16F10 melanoma colonization in lungs in mice. It was found that ethanol administration significantly inhibited the resistance of mice to C. neoformans infection, IL-2 production, active systemic anaphylaxis induction, serum TNF- alpha production and NO production. Ethanol administration significantly enhanced lung colonization when it was administered before i.v. melanoma inoculation. These results demonstrate that ethanol may play a critical role in tumorigenesis and immunoregulation as an immunomodulator.
Anaphylaxis*
;
Animals
;
Carcinogenesis
;
Colon
;
Cryptococcus neoformans
;
Cytokines*
;
Ethanol
;
Interleukin-2
;
Lung
;
Melanoma*
;
Mice
;
Nitric Oxide*
;
Ovalbumin
;
Tumor Necrosis Factor-alpha
3.A Case of the Giant Aneurysm in the Distal Portion of the Posterior Cerebral Artery: A Case Report.
Journal of Korean Neurosurgical Society 2000;29(7):963-967
No abstract available.
Aneurysm*
;
Posterior Cerebral Artery*
4.Clinical study of truncal vagotomy with pyloroplasty for perforation of duodenal ulcer.
Kil Young PARK ; Jin Young KIM ; Jong Ha SON
Journal of the Korean Surgical Society 1991;41(4):421-430
No abstract available.
Duodenal Ulcer*
;
Vagotomy, Truncal*
5.Echocardiographic Studies on Mitral Valvular Heart Disease.
Dae Ha KIM ; Young Jin KIM ; Hak Chung LEE
Korean Circulation Journal 1978;8(2):45-51
Echocardiography was done with Ekoline 20 model of Smith Kline Instrument in 91 patients of mitral valvular heart disease, 46 with mitral stenosis, 10 with mitral insufficiency, 38 with mitral stenoinsufficinency and 115 normal controls. The results obtained are as follows. 1. Right ventricular dimension was 13.61+/-5.61 mm/sq m. in normal controls, 16.50+/-5.06mm/sq m. in mitral stenosis, 20.17+/-3.28mm/sq m. in mitral insufficiency, 18.61+/-8.48mm/sq m. in mitral stenoinsufficiency revealing significant increment in all mitral valvular disease groups but there was no significant difference btw. each disease groups. 2. Left ventricular end-diastolic dimensions was 29.83+/-7.06mm/sq m. in normal controls, 41.57+/-7.77mm/sq m. in mitral insufficinency, 38.48+/-10.22mm/sq m. in mitral stenoinsufficiency revealing significant increment but there was no significant difference btw. mitral stenosis and normal controls. 3. Left atrial dimension was 17.57+/-4.96mm/sq m. in normal controls, 33.22+/-5.32mm/sq m. in mitral stenosis, 35.96+/-7.35mm/sq m. in mitral insufficiency, 35.00+/-8.22 in mitral stenoinsufficiency revealing significnat increment in whole mitral valvular disease. 4. E-F slope was 90.76+/-30.20mm/sec in normal controls 18.08+/-10.3mm/sec in mitral stenosis, 29.52+/-19.3mm/sec in mitral stenoinsufficiency revealing marked decrement. In mitral insufficiency, it was 65.3+/-45.4mm/sec revealing significant decrement but not so severe as previous. 5. There was no significant difference between normal controls and mitral valvular disease in valve excursion. 6. Left atrial dimension to aortic root size was 1.13+/-0.31 in normal controls, 1.77+/-0.63 in mitral stenosis, 1.56+/-0.60 in mitral regurgitation and 1.82+/-0.56 in mitral stenoinsufficinecy revealing significant increment in whole mitral valvular heart disease.
Echocardiography*
;
Heart Valve Diseases*
;
Humans
;
Mitral Valve Insufficiency
;
Mitral Valve Stenosis
6.Indication of Segmental Ostectomy by Bicoronal Approach in Reduction Maloplasty.
Young Hwan KIM ; Dong Ho HA ; Dong Il KIM
Journal of the Korean Society of Aesthetic Plastic Surgery 2001;7(1):63-68
No abstract available.
7.Apolipoprotein E Gene Polymorphism and Plasma Lipid Levels in Male Korean Patients with Chronic Renal Failure.
Yoon Ha LEE ; Hye Young KIM ; Wooseong HUH ; Se Ho CHANG ; Yoon Goo KIM ; Dae Joong KIM ; Ha Young OH
Korean Journal of Nephrology 1998;17(4):583-590
Accelerated atherosclerosis is not only a frequent complication but also the most common cause of death in patients with chronic renal failure (CRF). Although mechanisms are unclear, disorder of lipid metabolism may be a major factor. Since apolipo-protein (apo) E is known to play a major regulatory role in lipid metabolism, we evaluated apo E genotype in 72 male patients with CRF and compared with that in 194 rnale normal controls. In addition, we measured plasma lipid and apolipoprotein concentrations and evaluated them according to apo E genotype in patients and controls. Apo E genotype was determined with the INNO-LiPA Apo E kit (Innogenetics, Belgium), which is based on reverse hybridization. The results are as follows ; 1) The distribution of the three major apo E alleles in patients with CRF ( e 2: 6.2%, e 3: 80.6%, e 4: 13.2%) was not different from that in controls ( e 2: 4.1%, e 3: 87.6%, e 4: 8.3%). 2) In patients with CRF, total cholesterol, lowdensity lipoprotein (LDL) and high-density lipoprotein (HDL) levels were significantly lower and the triglyceride and lipoprotein (a) levels were significantly higher than those in controls. 3) In controls, E 4/3 group had significantly lower levels of HDL than E 3/3 and E 3/2 groups. In patients with CRF, E 4/3 group had significantly higher levels of total cholesterol and apo B lipoprotein than E3/2 group. In conclusion, although there was no significant difference in the apo E genotype frequencies between male patients with CRF and controls, apo E polymorphism may play an important role in the determination of individual differences in plasma lipids in male patients with CRF.
Alleles
;
Apolipoproteins B
;
Apolipoproteins E
;
Apolipoproteins*
;
Atherosclerosis
;
Cause of Death
;
Cholesterol
;
Genotype
;
Humans
;
Individuality
;
Kidney Failure, Chronic*
;
Lipid Metabolism
;
Lipoprotein(a)
;
Lipoproteins
;
Male*
;
Plasma*
;
Triglycerides
8.Acute hepatitis in a 10 month old girl with Rubeola.
Youn Ha KANG ; Young Min AHN ; Kyo Sun KIM
Journal of the Korean Pediatric Society 1985;28(2):174-176
No abstract available.
Female*
;
Hepatitis*
;
Humans
;
Infant*
;
Measles*
9.Clinical trial with intraperitoneal hyperthermic perfusion for intraabdominal cancer with peritoneal metastasis.
Jin Young KIM ; Soung Kee HONG ; Jong Ha SON
Journal of the Korean Surgical Society 1992;42(2):199-205
No abstract available.
Neoplasm Metastasis*
;
Perfusion*
10.The Effect of Decreased Serum Glucose on Collagen Contents of Penile Tunica Albuginea and Endothelial Change of Corpus Cavernosum in Long Evans Rat.
Hyun Pyo HONG ; Dae Yul YANG ; Ha young KIM
Korean Journal of Urology 2001;42(6):650-656
PURPOSE: It is reported that 65% of diabetic male patients over 60 of their age are impotent. However, there is no report concerning the effect of serum glucose control on erectile dysfunction in diabetic patient. This study was performed to evaluate the effects of serum glucose control on erectile dysfunction. MATERIALS AMD METHODS: The development of Diabetes mellitus was defined that the serum glucose level was above 200mg/dL in random test at 25 weeks. We designed the experimental specimen into 3 groups; group I: diabetic OLETF (Otsuka Long Evans Tokushima Fatty) rats without blood sugar control (n=10), group II: diabetic OLETF rats with blood sugar control with 4U insulin subcutaneous injection daily from 26 to 46 weeks (n=10), group III: diabetic OLETF rats with blood sugar control with 10U insulin subcutaneous injection daily from 26 to 46 weeks (n=10). We estimated the collagen content of penile tunica albuginea with the scanning electron microscopy and observed the endothelial layers of corpus cavernosum with the transmission electron microscopy in each group. RESULTS: The serum glucose level was 249 +/- 4.1mg/dL, 234 +/- 2.7mg/dL, 215 +/- 3.0mg/dL respectively in group I, II, III, and decreased in order of group II, III. The differences among groups were statistically significant (p<0.05). The thickness of collagen bundles of penile tunica albuginea was 0.98 +/- 0.1 micrometer, 0.94 +/- 0.3 micrometer, 0.92 +/- 0.1 micrometer respectively in group I, II, III, and decreased in order of group II, III. The differences among groups were statistically significant (p<0.05). The endothelial layers of corpus cavernosum were decreased in II, III. CONCLUSIONS: The serum glucose control in diabetic rats decreases the collagen con tents in penile tunica albuginea and the endothelial layers of corpus cavernosum.
Animals
;
Blood Glucose*
;
Collagen*
;
Diabetes Mellitus
;
Endothelium
;
Erectile Dysfunction
;
Humans
;
Injections, Subcutaneous
;
Insulin
;
Male
;
Microscopy, Electron, Scanning
;
Microscopy, Electron, Transmission
;
Rats*
;
Rats, Inbred OLETF