1.Clinical analysis of 34 diffuse axonal injured (DAI) patients below GCS 8.
Yonsei Medical Journal 1992;33(4):326-336
A consecutive series of 34 severe head-injured patients (DAI) were studied prospectively. Patients were categorized according to a new, simple classification system comprised of four lesion types according to the compression or obliteration of the ventricles or cisterns. Five patients belonged to type II and 19 patients to type IV. Each type was further subdivided into two GCS score ranges (5 to 8 and below 5). The distribution of the posttraumatic infarction was mainly in the frontal and temporal lobes (60% of all cases). Our data demonstrated that the ICP was significantly lower at a 30 degrees head elevation than at 0 degree (18.6 +/- 7.21 mmHg vs 23.0 +/- 10.60 mmHg. t = 4.22 p< 0.001), but head position did not statistically affect CPP (69.4 +/- 19.86 mmHg vs 68.2 +/- 19.87 mmHg. t = -0.54, p< 0.59). The effect of intensive therapy on ICP, CPP and AVDO2 was studied in all cases, employing steroids and diuretics in a modified intensive care scale. In cases where barbiturates were employed, there were statistically significant changes in ICP and AVDO2 (p< 0.001), but CPP was not affected (p< 0.59). Surviving patients were analyzed by using the GOS and the neurological grading score (NGS, Nihon University) of the persistent vegetative state. Our data suggests that head elevation of 30 degrees and barbiturate therapy are more effective on ICP and AVDO2, and NGS more exact than GOS in vegetative patients.
Adolescent
;
Adult
;
Aged
;
Cerebrovascular Circulation
;
Craniocerebral Trauma/*physiopathology/radiography
;
*Glasgow Coma Scale
;
Human
;
Intracranial Pressure
;
Middle Age
;
Oxygen/blood
;
Posture
;
Prospective Studies
;
Tomography, X-Ray Computed
2.Enhancing effect of IL-2, IFN-gamma and poly(A). poly(U) on growth inhibition of murine lymphocytes against cryptococcus neoformans.
Young Min PARK ; Tai You HA ; Byong Suk PARK
Journal of the Korean Society for Microbiology 1991;26(1):105-116
No abstract available.
Cryptococcus neoformans*
;
Cryptococcus*
;
Interleukin-2*
;
Lymphocytes*
3.Bilateral breast carcinoma.
Tea Ha PARK ; Il Young PARK ; Jai Hak LEE
Journal of the Korean Cancer Association 1991;23(2):436-442
No abstract available.
Breast Neoplasms*
;
Breast*
4.The Effect of Job Stress and Social Support on the Organizational Effectiveness of Hospital Employees.
Jong Wook KO ; Young Joon SEO ; Ha Young PARK
Korean Journal of Preventive Medicine 1996;29(2):295-308
The purpose of this study is to investigate the effect of job stress and social support on the organizational effectiveness of hospital employees and to examine the role of social support in the experience of job stress among the employees. Previous studies have yielded mixed results regarding the role of social support. Some studies provide supporting evidence for the buffering effect of social support, while others do not. Still others report findings about reverse buffering effects. These inconsistent findings are, in part, accounted for by methodological problems such as poor measurement, small sample size, and the existence of high multicollinearity. To examine more rigorously the role of social support in relation to the negative effects of job stress, this study was carefully designed to overcome methodolgical shortcomings found in the past research. In addition, unlike the previous studies, which were concerned mostly with health-related variables as consequences of job stress, in this study, three work-related variables (job satisfaction, organizational commitment, and intent to stay) which had close relationships with organizational effectiveness were examined as output variables. The sample used in this study consisted of 353 employees from a university hospital in the suburbs of seoul. Data were collected with self-administered questionnaires and analyzed using canonical analysis and hierarchical regression analysis. The results of this study indicate that; (l) job stress has negative main effects on job satisfaction, organizational commitment, and intent to stay; (2) social support has positive main effects on the same three output variables, (3) social support does not moderate the harmful effects of job stress on the three outcome variables, and (4) the three-way interaction effects of (social support * job stress * gender) and of (social support * job stress * education) are not supported The implications of these findings for the management of human resources are discussed.
Humans
;
Job Satisfaction
;
Surveys and Questionnaires
;
Sample Size
;
Seoul
5.Clinical study of truncal vagotomy with pyloroplasty for perforation of duodenal ulcer.
Kil Young PARK ; Jin Young KIM ; Jong Ha SON
Journal of the Korean Surgical Society 1991;41(4):421-430
No abstract available.
Duodenal Ulcer*
;
Vagotomy, Truncal*
6.Effects of Capsaicin on Production of Cytokines and Nitric Oxide, Salmonella Infection and NF-kappa B Activation.
Tai You HA ; Suhn Young IM ; Jae Seung PARK ; Hyun Ju HA ; Du Young CHOI
Korean Journal of Immunology 1998;20(3):349-363
"Capsaicin, the pungent principle of hot peppers, is a neurotoxin that depletes primary sensory neurons of neuropeptides like tachykinin. The objectives of these experiment was to examine the effects of capsaicin on Salmonel/a typhimurium-induced production of cytokines such as TNF-a, IL-1B, IL-6, IL-10 and IL-12 and on production of nitric oxide in peritoneal macrophages. In addition, the effects of capsaicin on survival rates of S. typhimurium-infected mice and on nuclear transcription factor (NF-kB) activation were also investigated. Mice were pretreated with a single s.c. injection of 100 ug of capsaicin and were infected i.v. with S. typhimurium (5xO5/mouse) in 0.2 ml volume after capsaicin pretreatment. The serum cytokine levels were measured 30, 60, 120, 180 and 240 min after Salmonella infection, using ELISA kits. The activation of NF-B was also examined by gel shift assay in spleens, thymuses and brains of mice that had been pretreated with a single s.c. injection of 100 ug of capsaicin. It was found that Sa/mone/la infection induced the production of TNF-a, IL-1B, IL-6, IL-10 and IL-12, but capsaicin pretreatment inhibited the production of TNF-a, IL-1B, IL-10 and IL-12, but enhanced IL-6 production 120 min after Salmonella infection. Interestingly, the capsaicin pretreatment inhibited the activation of NF-kB in spleens and thymuses. There were no differences in the numbers of bacteria in livers, brains, spleens, kidneys and lungs between capsaicin- pretreated mice and the control animals in applied experimental conditions. Suprisingly, however, capsaicin pretreatment increased both the survival rates of Sa/mone//a-infected mice and production of nitric oxide by peritoneal macrophages compared with capsaicin-untreated control mice. Taken together, these results indicate that the capsaicin-sensitive primary sensory neurons may play an important modulatory role in the production of cytokine, nitric oxide and NF-B activation and the pathogenesis of salmonellosis."
Animals
;
Bacteria
;
Brain
;
Capsaicin*
;
Cytokines*
;
Enzyme-Linked Immunosorbent Assay
;
Interleukin-10
;
Interleukin-12
;
Interleukin-6
;
Kidney
;
Liver
;
Lung
;
Macrophages, Peritoneal
;
Mice
;
Neuropeptides
;
NF-kappa B*
;
Nitric Oxide*
;
Salmonella Infections*
;
Salmonella typhimurium
;
Salmonella*
;
Sensory Receptor Cells
;
Spleen
;
Survival Rate
;
Tachykinins
;
Thymus Gland
;
Transcription Factors
7.Short-term outcome in manic patients with delusions or hallucinations.
Hee Cheol KIM ; Young Nam PARK ; Jae Chang HA
Journal of Korean Neuropsychiatric Association 1992;31(4):697-707
No abstract available.
Delusions*
;
Hallucinations*
;
Humans
8.Training Effectiveness and Behavior towards the Elderly of Caregiver Trainees.
Journal of Korean Academy of Adult Nursing 2010;22(2):200-210
PURPOSE: The purpose of this study was to examine the training effectiveness and behavior towards the elderly of 180 caregiver trainees. METHODS: Data were collected from five caregiver training institutions located in G city. All subjects were surveyed about the training effectiveness and behavior towards the elderly by using the Training Effectiveness Scale and the Behavior towards the Elderly Scale. Data were analyzed by SPSS/WIN 12.0 program. RESULTS: The study subjects gained a training effectiveness score of 3.84 out of 5 points and a behavior towards the elderly score 3.40 out of 4 points. The training effectiveness differed significantly depending on subject's characteristics, intention to work as a caregiver, and hours of training. There were significant differences in behavior towards the elderly depending on their age and hours of training. The training effectiveness was significantly correlated with the level of behavior towards the elderly. CONCLUSION: These findings demonstrated the necessity of developing a level of educational training that will help improve caregiver trainees' care by positively changing their behavior towards the elderly.
Aged
;
Caregivers
;
Humans
;
Intention
9.The comparative study of the surgical treatment of axillary osmidrosis by inaba's manual, and combined subcutaneous tissue shaving method.
Dong Ha HWANG ; Ki Young AHN ; Dae Hwan PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(6):1310-1316
No abstract available.
Subcutaneous Tissue*
10.Driving of Motor Vehicles of the Epileptic Patients.
Yeung Ju BYUN ; Mee Young PARK ; Jung Sang HA
Yeungnam University Journal of Medicine 1994;11(1):16-29
No abstract available.
Humans
;
Motor Vehicles*