Non-melanoma skin cancer in a psoriasis patient is known to be associated with the treatments for psoriasis such as long-term use of PUVA and cyclosporine rather than the psoriasis itself. We report here on a case of double primary squamous cell carcinoma and acanthosis on a patient who had no history of oral steroid and cyclosporine management. A 44 years old male patient presented for ulcerative skin lesion on both soles. He underwent an operation of wide excision and reconstruction for two separated malignant lesions with using a free flap and skin graft, respectively. Another skin lesion was found on his finger during the follow-up period and excisional biopsy was performed. No evidence of recurrence or metastasis of the squamous carcinoma was found during 2 years follow-up. The excisional biopsy done on his finger was revealed to be acanthosis and no further surgical intervention was needed. This case has an implication that physicians should consider the possibility of multiple skin cancers in a psoriasis patient irrespective of having received immunosuppression therapy, and physicians should try to make an early diagnosis to minimize the patient's morbidity and mortality.
Biopsy ; Carcinoma, Squamous Cell ; Cyclosporine ; Early Diagnosis ; Fingers ; Follow-Up Studies ; Free Tissue Flaps ; Humans ; Immunosuppression ; Male ; Neoplasm Metastasis ; Psoriasis ; Recurrence ; Skin ; Skin Neoplasms ; Transplants ; Ulcer

No abstract available.
Cutaneous Fistula ; Glomerulonephritis, Membranous* ; Humans ; Sarcoma, Kaposi*

No abstract available.

Varicocele has been considered the most common identifiable cause of adult infertility. but little has been known on the significance of histology and volume according to the grade in adults with varicocele. Herein, we have assessed bilateral testicular size before surgical ligation and performed bilateral testicular biopsies at the time of surgical ligation. The volume of each testes in adults with varicocele was smaller than those of normal adults and it was statistically significant. The grades of varicocele did not have a significant effect on differential testicular volumes, although the volume of the left testis in adults with varicocele was always less than that of the right testis. Histologic changes were showed degeneration of germinal epithelium, focal tubular atrophy, and premature sloughing of germinal epithelium into the lumen of the tubules. Tubular thickening was seen in most or the cases. Spermatogenesis was generally reduced in patients with varicocele, but there was no difference between the right and left testis. There was no correlation between the grade of the varicocele and the reduction in spermatogenesis.
Adult* ; Atrophy ; Biopsy ; Epithelium ; Humans ; Infertility ; Ligation ; Spermatogenesis ; Testis ; Varicocele*

No abstract available.
Holoprosencephaly*

Congenital hepatic fibrosis is an uncommon disease of children and young adults with two major risks: gastrointestinal hemorrhage caused by portal hypertension, and cholangitis related to bacterial infection of dilated intrahepatic bile ducts. It is characterizeed by stony hard hepatomegaly and portal hypertension with rather well preserved hepatic function and architecture, and frequent association of the renal lesions. We have recently experienced a case of congenital hepatic fibrosis in a 24 year-old Korean male. The chief complaint was hematemesis from esophageal varices. There were marked hepatosplenomegaly, mild pancytopenia and the liver function test was within normal engorgement and dilatation of portal and splenic veins and multiple cysts of both kidneys.
Child ; Adult ; Male ; Female ; Humans ; Cysts

No abstract available.

No abstract available.
Anemia, Aplastic* ; Hepatitis*

No abstract available.
Prune Belly Syndrome*