Non-melanoma skin cancer in a psoriasis patient is known to be associated with the treatments for psoriasis such as long-term use of PUVA and cyclosporine rather than the psoriasis itself. We report here on a case of double primary squamous cell carcinoma and acanthosis on a patient who had no history of oral steroid and cyclosporine management. A 44 years old male patient presented for ulcerative skin lesion on both soles. He underwent an operation of wide excision and reconstruction for two separated malignant lesions with using a free flap and skin graft, respectively. Another skin lesion was found on his finger during the follow-up period and excisional biopsy was performed. No evidence of recurrence or metastasis of the squamous carcinoma was found during 2 years follow-up. The excisional biopsy done on his finger was revealed to be acanthosis and no further surgical intervention was needed. This case has an implication that physicians should consider the possibility of multiple skin cancers in a psoriasis patient irrespective of having received immunosuppression therapy, and physicians should try to make an early diagnosis to minimize the patient's morbidity and mortality.
Biopsy ; Carcinoma, Squamous Cell ; Cyclosporine ; Early Diagnosis ; Fingers ; Follow-Up Studies ; Free Tissue Flaps ; Humans ; Immunosuppression ; Male ; Neoplasm Metastasis ; Psoriasis ; Recurrence ; Skin ; Skin Neoplasms ; Transplants ; Ulcer

No abstract available.
Cutaneous Fistula ; Glomerulonephritis, Membranous* ; Humans ; Sarcoma, Kaposi*

No abstract available.
Heart Arrest, Induced*

Congenital hepatic fibrosis is an uncommon disease of children and young adults with two major risks: gastrointestinal hemorrhage caused by portal hypertension, and cholangitis related to bacterial infection of dilated intrahepatic bile ducts. It is characterizeed by stony hard hepatomegaly and portal hypertension with rather well preserved hepatic function and architecture, and frequent association of the renal lesions. We have recently experienced a case of congenital hepatic fibrosis in a 24 year-old Korean male. The chief complaint was hematemesis from esophageal varices. There were marked hepatosplenomegaly, mild pancytopenia and the liver function test was within normal engorgement and dilatation of portal and splenic veins and multiple cysts of both kidneys.
Child ; Adult ; Male ; Female ; Humans ; Cysts

No abstract available.

PURPOSE: To evaluate the outcome of ductal carcinoma in situ (DCIS) patients who underwent surgery followed by radiation therapy (RT). MATERIALS AND METHODS: We retrospectively reviewed 106 DCIS patients who underwent surgery followed by postoperative RT between 1994 and 2006. Ninety-four patients underwent breast-conserving surgery, and mastectomy was performed in 12 patients due to extensive DCIS. Postoperative RT was delivered to whole breast with 50.4 Gy/28 fx. Tumor bed boost was offered to 7 patients (6.6%). Patients with hormonal receptor-positive tumors were treated with hormonal therapy. RESULTS: The median follow-up duration was 83.4 months (range, 33.4 to 191.5 months) and the median age was 47.8 years. Ten patients (9.4%) had resection margin <1 mm and high-grade and estrogen receptor-negative tumors were observed in 39 (36.8%) and 20 (18.9%) patients, respectively. The 7-year ipsilateral breast tumor recurrence (IBTR)-free survival rate was 95.3%. Resection margin (<1 or > or =1 mm) was the significant prognostic factor for IBTR in univariate and multivariate analyses (p < 0.001 and p = 0.016, respectively). CONCLUSION: Postoperative RT for DCIS can achieve favorable treatment outcome. Resection margin was the important prognostic factor for IBTR in the DCIS patients who underwent postoperative RT.
Breast ; Breast Neoplasms ; Carcinoma, Ductal* ; Carcinoma, Intraductal, Noninfiltrating* ; Estrogens ; Follow-Up Studies ; Humans ; Mastectomy ; Mastectomy, Segmental ; Multivariate Analysis ; Recurrence ; Retrospective Studies ; Survival Rate ; Treatment Outcome*

No abstract available.

No abstract available.
Anemia, Aplastic* ; Hepatitis*

No abstract available.
Holoprosencephaly*