1.Subungual Glomus Tumor: Report of A Case.
Seong Un KIM ; Chung Koo CHO ; Tae Ha WOO
Korean Journal of Dermatology 1976;14(1):69-71
One case of subungual glomus tumor was reported which had characteristic clinical manifestations of paroxysmal pain and tenderness for about 20 years. Histopathologically it was confirmed as subungual glomus tumor. This case was treated completely with simple surgics,l excision of the mass.
Glomus Tumor*
2.Extracranial Extension of A Pterional Meningioma: Case Report.
Young KIM ; Young Soo HA ; Jin Un SONG
Journal of Korean Neurosurgical Society 1984;13(4):743-747
The authors report a case of pterional meningioma invading the sphenoid bone, orbital roof and lateral orbit, and temporal bone with hyperostosis, which extended into temporal muscle. Extensive removal of orbital, sphenoid and basal skull bone was carried out with total excision of tumor mass in and out of the cranium. Preoperative exophthalmos still remained postoperatively. The mode of extension, result of surgery and CT findings are discussed.
Exophthalmos
;
Hyperostosis
;
Meningioma*
;
Orbit
;
Skull
;
Sphenoid Bone
;
Temporal Bone
;
Temporal Muscle
3.Expression of CD44 Splice Variants(v4/5 and v6), alpha-Smooth Muscle Actin, and nm23 Proteins in IB-IIB Uterine Cervical Cancer.
Hee Kyung CHANG ; Man Ha HUH ; Dong Hee KIM ; Un Dong PARK
Korean Journal of Pathology 1997;31(6):546-556
We examined the expressions of CD44 splice variants (v4/5, v6), alpha-smooth muscle actin, nm23 to evaluate their roles as prognostic factors in 70 cases of uterine cervical carcinoma (stage IB to IIB) who were surgically treated from January 1989 to June 1990 with a clinical follow-up of a minimum of 5 years. The expression was examined by an immunohistochemical method using archival formalin fixed paraffin embedded tissue. In the 70 cases, 61 cases were squamous cell carcinoma and 9 cases were adenocarcinoma. CD44v4/5, CD44v6, alpha-smooth muscle actin, and nm23 were detected in 41.4%, 70%, 100%, and 74.3% of tumor samples, respectively. CD44 splice variants and nm23 showed membrane and cytoplasmic staining of tumor cells, respectively. The expression of alpha-smooth muscle actin showed cytoplasmic staining confined to stromal cells and was classified into three grades by the extent in stromal cells: with less than 10% of stromal cells; 32.9%, 10-50% of stromal cells; 40.0%, more than 50%; 27.1%. These expressions were not correlated with histologic types, lymph node involvement, recurrence, and grades of tumor infiltrating lymphocyte (TIL). But CD44v4/5 had significantly inverse correlation with TIL (p=0.049). The expression of CD44v4/5 was significantly correlated with that of CD44v6 (p=0.05), and that of alpha-smooth muscle actin was inversely correlated with that of nm23 (p=0.049). In conclusion, in FIGO IB-IIB uterine cervical carcinoma CD44 variants, nm23, and SMA show high prevalence, however, with little prognostic significance assessed by recurrence and lymph node metastasis.
Actins*
;
Adenocarcinoma
;
Carcinoma, Squamous Cell
;
Cytoplasm
;
Follow-Up Studies
;
Formaldehyde
;
Lymph Nodes
;
Lymphocytes
;
Membranes
;
Neoplasm Metastasis
;
Paraffin
;
Prevalence
;
Recurrence
;
Stromal Cells
;
Uterine Cervical Neoplasms*
4.Study on Pubertal Changes in Adolescent Girls.
Sang Mi HA ; Ki Soo PAI ; Un Jun HYOUNG ; Duk Hi KIM
Journal of the Korean Pediatric Society 1990;33(7):989-998
No abstract available.
Adolescent*
;
Female*
;
Humans
5.A Case of Intramedullary Glioblastoma Multiforme in Child.
Moon Chan KIM ; Young Soo HA ; Jin Un SONG
Journal of Korean Neurosurgical Society 1976;5(2):259-264
A case of primary cervical intramedullary glioblastoma multiforme which is infrequently reported is presented. An 11 year old girl was admitted to the Department of Neurosurgery, Catholic Medical College in September 1976 because of flaccid paralysis of both upper extremities, neck pain and vomiting for 3 months. On admission, the patient was found to have flaccid paralysis of both arms and weakness of both legs. Sensory examination revealed hyperthesia below C2 dermatome. Babinski's toe sign was positive bilaterally and she was unable to void. Plain cervical spine revealed widening of interpedicular distance at C5 & 6. Myelogram through lumbar and cisternal route showed obstruction and widening of cord at the level of C4 & 7 respectively. Total laminectomy was performed through C3 to C6 and a purplish-blue mass was extruded out through the dorsal myelotomy. Pathologic diagnosis of the tumor was glioblastoma multiforme. Postoperatively there was marked improvement of motor power of all limbs. The patient has not shown any worsening in neurological status until this paper is submitted since she was discharged from the hospital October 1976.
Arm
;
Child*
;
Diagnosis
;
Extremities
;
Female
;
Glioblastoma*
;
Humans
;
Laminectomy
;
Leg
;
Neck Pain
;
Neurosurgery
;
Paralysis
;
Spine
;
Toes
;
Upper Extremity
;
Vomiting
6.A Case of Intramedullary Glioblastoma Multiforme in Child.
Moon Chan KIM ; Young Soo HA ; Jin Un SONG
Journal of Korean Neurosurgical Society 1976;5(2):259-264
A case of primary cervical intramedullary glioblastoma multiforme which is infrequently reported is presented. An 11 year old girl was admitted to the Department of Neurosurgery, Catholic Medical College in September 1976 because of flaccid paralysis of both upper extremities, neck pain and vomiting for 3 months. On admission, the patient was found to have flaccid paralysis of both arms and weakness of both legs. Sensory examination revealed hyperthesia below C2 dermatome. Babinski's toe sign was positive bilaterally and she was unable to void. Plain cervical spine revealed widening of interpedicular distance at C5 & 6. Myelogram through lumbar and cisternal route showed obstruction and widening of cord at the level of C4 & 7 respectively. Total laminectomy was performed through C3 to C6 and a purplish-blue mass was extruded out through the dorsal myelotomy. Pathologic diagnosis of the tumor was glioblastoma multiforme. Postoperatively there was marked improvement of motor power of all limbs. The patient has not shown any worsening in neurological status until this paper is submitted since she was discharged from the hospital October 1976.
Arm
;
Child*
;
Diagnosis
;
Extremities
;
Female
;
Glioblastoma*
;
Humans
;
Laminectomy
;
Leg
;
Neck Pain
;
Neurosurgery
;
Paralysis
;
Spine
;
Toes
;
Upper Extremity
;
Vomiting
7.Expression of tumor necrosis factor receptor superfamily in carotid atheroma.
Mi Hyang KWAK ; Mi Kyung KIM ; Se Hwa KIM ; Won Ha LEE ; Un Ho RYOO ; Jeong Euy PARK
Korean Circulation Journal 2000;30(12):1563-1573
BACKGROUND AND OBJECTIVES: It has been reported that various inflammatory and immune reactions are involved in the development and progression of atherosclerosis. We tried to investigate whether the TNF receptor superfamilies are involved in the development and progression of atherosclerosis. MATERIALS AND METHOD: Thirteen carotid atheroma specimens(frozen sections : 10 cases, paraffin section : 5 cases) were obtained from the patients who underwent carotid endarterectomy at Samsung Medical Center and one normal aortic tissue was obtained from a transplantation donor in brain death. In the carotid endarterectomy specimens and a normal aortic tissue , the expressions of R110(TR1), 139(TR2) and DR3(TR3), members of the TNF receptor superfamilies were evaluated by immunohistochemical staining with monoclonal antibodies. Simultaneously, we evaluated the expressions of foam cells, smooth muscle cells, T-lymphocytes and B-lymphocytes. RESULTS: Immunohistochemical analysis identified a strong expressions of foam cells and smooth muscle cells in all atheroma. But, the expression of T-lymphocytes was minimal and that of B-lymphocytes was rare. The expression of DR3(TR3) was seen in all atheroma as strongly positive. The expression of 139(TR2) was observed well in frozen sections, but not in paraffin sections. Whereas, that of R110(TR1) was observed in paraffin sections as weakly positive, but not in frozen section. The areas where the TNF receptor superfamilies were expressed correlated to the area of foam cell presence. The expression of DR3 also correlated with expression of smooth muscle cells. In normal aortic tissue, the expression of inflammatory cells or TNF receptor superfamilies was not observed except smooth muscle cells which were observed in normal artery. CONCLUSION: Foam cells and smooth muscle cells were abundantly present in atheroma. The TNF receptor superfamilies are expressed in the atheroma and the region of expression was coincident with the presence of foam cells.
Antibodies, Monoclonal
;
Arteries
;
Atherosclerosis
;
B-Lymphocytes
;
Brain Death
;
Endarterectomy, Carotid
;
Foam Cells
;
Frozen Sections
;
Humans
;
Myocytes, Smooth Muscle
;
Paraffin
;
Plaque, Atherosclerotic*
;
Receptors, Tumor Necrosis Factor*
;
T-Lymphocytes
;
Tissue Donors
;
Tumor Necrosis Factor-alpha*
8.A Case of Vulvar Syringoma in a 9-year Old Child.
Dong Joo KIM ; Jong Heon BAEK ; Dong Yeup LEE ; Myoung Shin KIM ; Un Ha LEE ; Jeong Hee HAHM
Korean Journal of Dermatology 2015;53(1):74-76
No abstract available.
Child*
;
Humans
;
Syringoma*
;
Vulva
9.Cutaneous Metastasis from Pancreatic Cancer Simultaneously Developed on the Scalp and Chest.
Dong Yeup LEE ; Dong Joo KIM ; Soo Kyung LEE ; Myoung Shin KIM ; Un Ha LEE ; Jeong Hee HAHM
Korean Journal of Dermatology 2016;54(8):662-664
No abstract available.
Neoplasm Metastasis*
;
Pancreatic Neoplasms*
;
Scalp*
;
Thorax*
10.Aprotinin Therapy for Cardiac Operation in Adult -Full dose regimen.
Un Ha JANG ; Tae Yun OH ; Mi Hye KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1999;32(4):358-363
BACKGROUND: Recently, many cardiac centers have been using aprotinin to reduce operative bleeding in cardiac operations using cardiopulmonary bypass. A variety of reports have confirmed the effectiveness of the drug in cardiac operations. In addition to the operations which could be considered to cause severe operative bleeding such as redo operation, long cardiopulmonary bypass operation and etc, the use of aprotinin is increasing in the field of primary cardiac operations. Varying doses of regimen have been introduced since the first report by Royston et al, and also various opinions on the effectiveness and safeness of the each regimen have been reported. We reviewed our own experience of the full dose aprotinin regimen(Hammersmith regimen) retrospectively. MATERIAL AND METHOD: From October 1994 to February 1998, 40 cases of cardiac operative patients were randomized into two groups: aprotinin group(20 patients) which received a full dose aprotinin regimen and control group(20 patients) which did not receive aprotinin. To evaluate the degree of bleeding decrease, we analysed and compared the amount of postoperative 6 hours and 24 hours bleeding in the each group. To confirm the renal dysfunction, we measured the postoperative creatinine level. RESULT: In the amount of postoperative 6 hours bleeding, a statistically significant bleeding decrease was demonstrated in the aprotinin group compared to the control group(aprotinin group: 186+/-40cc, control group:409+/-69cc, P=0.010). Similar result was observed in the postoperative 24 hours(aprotinin group:317+/-53cc, control group: 671+/-133cc, P=0.024). CONCLUSION: We concluded that full dose regimen of aprotinin can remarkably reduce postoperative bleeding in cardiac operations without significant renal dysfunctions.
Adult*
;
Aprotinin*
;
Cardiopulmonary Bypass
;
Creatinine
;
Hemorrhage
;
Humans
;
Retrospective Studies
;
Thoracic Surgery