The study was performed on 41 patients using concurrently ultrasound and CT scanner. They were diagnosed surgically and by blood amylase quantified 3 fold higher than normal subjects. Kappa’s indicators were applied for evaluating the concord between ultrasound and CT scanned images. Results showed that both methods of diagnosis were effective for identification and monitoring acute inflammation of the pancrea. In the prognosis, CT scanning is great advantage, especially in necrosis of the parenchyme. Both were limited on the detection of hemorrhagic form of micronecrosis.
Diagnosis ; pancreatitis ; ultrasonography ; Tomography Scanners, X-Ray Computed

Pancreatitis, Acute Necrotizing; Patients; Image Processing, Computer-Assisted; From January 1996 to December 2000, at Viet Duc Hospital, 41 patients were undergone a CT scanning and at the end, an operation or an amylase quantitation with a threefold higher blood level. In most of cases CT scanner showed a size of threefold large than normal pancrea. However no larger size was found in the cases of necrotic of the periphery of the pancrea associated with peripheral infiltrated tissues, on CT image the peripheral infiltrated tisues, the dim borders, the rough parenclyma before and after injection of photocontrast agent are significant signs for diagnosing acute hemorrhagic necrotic pancreatitis
Pancreatitis, Acute Necrotizing ; Patients ; Image Processing, Computer-Assisted

From Jan 1998 to Dec 2000 a study on 41 acute pancreatitis patients was conducted by comparation description with ultrasound and CT scanning. The diagnostic results of two techniques are coincident considerably such as the large dimension of pancrea, the infiltration of the tissues around the pancrea, the gangrene of parenchyma. However, CT is preferable to ultrasound in the prognosis, these two techniques were suitable in diagnosis of acute pancreatitis, ultrasound can be used as a detective tool for discovering preliminarily acute pancreatitis and afterwards, CT can conducted to evaluate the prognosis. These techniques can let pass the dispensed hemorrlagy and the gangrene of parenchyma
Pancreatitis, Acute Necrotizing ; ultrasonography ; Patients ; Tomography, Emission-Computed

11 patients aged 24-70, with pancreatitis admitted at Viet Duc Hospital from Jan 1998 to Dec 2002. Ultrasonic examination was carried out and terminated diagnosis was performed surgically, blood level of amylase increased by 3 times versus normal level. The highest incidence level is in the middle age (13/14 patients – 31,7%). Ultrasonic signs characteristic for acute pancreatitis of edematous form is enlarged pancrea with appeared edge, low echo or equal echo of pancrea parenchyma. In necrojy form of acute pancreatitis the pancrea edge is dim, pancrea parenchyma is unregulated with the mixed structure. In 9/41 patients, by ultrasound the pancrea is not appeared. Thus in accessing the pancrea, pancreatitis can be diagnosed with a sensibility of 81,23%
Pancreatitis ; Ultrasonics ; Pancreatitis, Acute Necrotizing

Endophytic fungi are promising sources for the production of podophyllotoxin-an important anticancer compound, replacing depleted medical plants. In this study, the endophytes associated with Dysosma difformis-an ethnomedicinal plant species were isolated to explore novel sources of podophyllotoxin. Fifty-three endophytic fungi were isolated and identified by morphological observation and ITS-based rDNA sequencing, assigning them to 27 genera in 3 divisions. Fusarium was found the most prevalent genus with a colonization frequency of 11.11%, followed by Trametes (9.26%) and Penicillium (7.41%). Phylogenetic trees were constructed for the endophytic fungi community in two collection sites, Ha Giang and Lai Chau, revealing the adaptation of the species to the specific tissues and habitats. Cytotoxic activity of endophytic fungal extracts was investigated on cancer cell lines such as SK-LU-1, HL-60, and HepG2, demonstrating strong anti-cancer activity of six isolates belonging to Penicillium, Trametes, Purpureocillium, Aspergillus, and Ganoderma with IC 50 value of lower than 10 10 µg/mL. The presence of podophyllotoxin was indicated in Penicillium, Trametes, Aspergillus and for the first time in Purpureocillium and Ganoderma via high-performance liquid chromatography, which implied them as a potential source of this anticancer compound.

Sphaeranthus africanus is commonly used as a traditional remedy for sore throats and pain treatment in Vietnam. The aerial parts have been studied for its anti-inflammatory and anti-proliferative properties. However, the antioxidant and antidiabetic potential of the plant has not been explored. In this work, hydrophilic extracts of the plant's aerial parts were prepared in order to investigate its antioxidant and anti-diabetic properties. Also, the cytotoxicity of the root was evaluated and compared to that of the aerial parts. All of the extracts inhibited lipid peroxidation with IC 50 values ranging from 2.05 to 3.56 µg/mL, indicating substantial antioxidant activity. At an IC 50 value of 4.80 μg/mL, the 50% ethanol extract exhibited the most potent inhibition of α-glucosidase. The cytotoxic activity of root extracts is 2 to 5-fold less than that of the aerial parts. Nevertheless, dichloromethane and ethyl acetate extracts of the root demonstrated a selective effect on leukemia cells, with no harm towards the normal HEK-293 cell line. This work provides a scientific support for the antioxidant and antidiabetic activity of the plant. Hence, it may find a promising material for the development of novel antioxidant and antidiabetic agents. More research can be conducted on the phytochemistry and anticancer activities of the plant’s root.