BACKGROUND: Because of the differences in dermatophytoses by ographic distribution in Korea, we studied the incidence of dermatophytoses in the Kyongju area. OBJECTIVE: The purpose of the study was to investigate the recant clinical and mycological features of dermatophytoses in the Kyongju area. METHODS: We evaluated the clinical and mycological aspects flermatophytoses in 431 patients from September 1992 to August 1994 in the Kyongju area. RESULTS: 1) The incidence of dermatophytoses was 7.8% out of a total of 5,549 out patients. 2) The incidence of dermatophytoses was Tinea(T.) pedis (36%), T. unguium (30.2%), T. corporis (12.0%), T. cruris, (11.5%), T. manus (7.3%), T. faic (2.2%), T. capitis (0.6%) in order of decreasing frequency. 3) Among the age groups, the in idence rate was highest in the third decade (21.3%). 4) The ratio of male to female patients was 1.5: l.5) Coexisting fungal infections were found in 1 patients (41.0%), and the cases of T. pedis with T. unguium was the most common. 6) In dercimatophytoses, the positive rate of KOH mount examination was 95.7 %, and the positive rate of culture was 77.6%. 7) Trichophytone T. rubrum was the most common causative organism of dermatophytoses (91.8%), T. mentagrophages (4.3%), T. verrucosum (2,3%), Microsporum(M.) canis (1.0%), M. gypseum (0.3%). Epidermoplyte floccosum (0.3%), presenting in order of decreasing freqiency. CONCLUSION: We find that the incidence rate of T. veriosum infection & coexisting dermatophytosis in the Kyongju area are higher than previous studies in Korea
Female ; Gyeongsangbuk-do* ; Humans ; Incidence ; Korea ; Male ; Outpatients ; Tinea* ; Trichophyton

Twenty-two cases of idiopathic myocardiopathy were observed during the period of 1962 to 1971 and follow up clinical study was made in 5 cases. The criteria of diagnosis was based mainly on exclusive diagnosis in etiology unknown marked cardiomegaly. 1) Male and female ratio of idiopathic myocardiopathy was 1.1:1 and age of onset were distributed from first decade to fifth decade with similar number of cases. 2) Cardinal symptoms were dyspnea, palpitation, chest pain and cough. Common physical findings were protodiastolic gallop (in 2 cases), moist rales (in 3 cases) and hepatomegaly(in 3 cases). 3) Laboratory findings were normal except elevated T.T.T. in one case. 4) Electrocardiogram were abnormal in all cases. There were 3 cases of left ventricular hypertrophy, 3 cases of non-specific ST-T changes and one case of first degree A-V block, intraventricular conduction defect, abnormal Q wave and low valtage, respectively. 5) After medical treatment, symptoms were improved in 4 cases but heart size was reduced in only one case and E.C.G. abnormalities were unchanged in all cases.
Age of Onset ; Cardiomegaly ; Cardiomyopathies* ; Chest Pain ; Cough ; Diagnosis ; Dyspnea ; Electrocardiography ; Female ; Follow-Up Studies ; Heart ; Humans ; Hypertrophy, Left Ventricular ; Male ; Respiratory Sounds

Metabolic acidosis (MA) is associated with increased proteolysis, increased osteoclast activity and blunted cardiac muscle response, but the effect of MA on various clinic al parameters in CAPD patients is not well known. To evaluate the effects of MA on serum albumin level and other nutritional parameters in CAPD patients, we studied 106 CAPD patients retrospectively who have had monthly biochemical measurement and urea kinetic studies every 6 months for more than 2 years. The patients were divided into three groups according to their mean total CO2 (tCO2) level of the 2-year follow-up (Group l; mean tCO2 < 22mM/L, Group ll; 22mM/L < or = mean tCO2 < 26mM/L, and Group lll; mean tCO2 > or = 26mM/L), and the clinical, biochemical, and urea kinetic data were compared among the three groups. 1)The mean age of the subjects was 46.9+/-12.2 years with a sex ratio of 1.2:1, the mean CAPD duration 28.3+/-21.8 months, mean body weight (Bwt) 59.0+/-8.9kg, %Bwt/IBW 104.1+/-11.5%, %LBM/Bwt 75.5+/-11.1% and well-nourished patients by subjective global assessment (SGA) were 65%. 2)The mean BUN, creatinine, total protein and albumin of all patients were 55.6+/-13.6mg/dL, 12.3+/-3.5mg/dL, 6.6+/-0.7g/dL and 4.0+/-0.4g/dL, respectively. In urea kinetic study, the mean NPCR, weekly Kt/ Vurea, SCCr and RRF were 0.96+/-0.16g/kg/day, 2.02+/-0.37, 63.7+/-18.4L/week/1.73m2, and 0.99+/-1.32ml/ min, respectively. 3)The mean age was significantly higher in group l (51.0+/-10.8) than those of group ll (47.0+/-12.4) and lll (42.6+/-11.4) (P<0.05). %Bwt/IBW of group l (114.4+/-15.8%) was also significantly higher than those of group ll (104.6+/-12.6%) and lll (103.5+/-13.7 %) (P<0.05), but there were no significant differences in sex ratio, CAPD duration, %LBM/Bwt, and SGA among the three groups. 4)The mean tCO2 in group l, group ll, and group lll were 20.6+/-1.2mM/L, 23.9+/-1.1mM/L, and 27.3+/-0.8mM/L, respectively. Compared to group lll, group l had significantly higher BUN (61.1+/-14.3 vs. 46.1+/-7.2mg/dL, P<0.05) and serum albumin (4.04+/-0.31 vs. 3.75+/-0.39g/dL, P<0.05), in spite of comparable dialysis dose and albumin loss into dialysate. 5)NPCR (1.02+/-0.21g/kg/day vs. 0.88+/-0.14g/kg/ day, P<0.05) and ultrafiltration volume (1.4+/-0.4 vs. 1.0+/-0.3, P<0.05) were significantly higher in group l than those of group lll. But there were no significant differences in Kt/Vurea, SCCr, RRF, and 24-hour dialysate loss of protein/albumin among the three groups. 6)No differences were observed among the three groups in the changes of body weight, %Bwt/IBW, %LBM/Bwt, BUN, albumin, NPCR, and RRF from the baseline values after the 2-year follow-up. 7)There were significant inverse correlations between the mean tCO2 level and NPCR (r=-0.33, P<0.001), %Bwt/IBW (r=-0.32, P<0.001), RRF (r=-0.29, P<0.005), and serum albumin level (r=-0.24, P<0.05). But, creatinine, %LBM/Bwt, and Kt/Vurea did not show any correlation with the mean tCO2 level. 8)Using stepwise multiple regression analysis, NPCR (beta=-0.3491, P<0.001), %Bwt/IBW (beta=-0.046, P<0.001), and ultrafiltration volume (beta=-0.0012, P< 0.005) were independent factors affecting the mean tCO2 level. In conclusion, low total CO2 level in long-term CAPD patients may reflect increased protein intake and mild to moderate degree of metabolic acidosis may not affect the nutritional status of well-dialyzed CAPD patients.
Acidosis* ; Body Weight ; Creatinine ; Dialysis ; Follow-Up Studies ; Humans ; Myocardium ; Nutritional Status ; Osteoclasts ; Peritoneal Dialysis, Continuous Ambulatory* ; Proteolysis ; Retrospective Studies ; Serum Albumin* ; Sex Ratio ; Ultrafiltration ; Urea

No abstract available.
Catheters* ; Peritoneal Dialysis, Continuous Ambulatory*

No abstract available.
Asthma* ; Dyspnea* ; Humans ; Respiratory Function Tests*

OBJECTIVE: To assess the effect of recombinant human leukemia inhibitory factor on in vitro development of 1-cell ICR mouse embryo. MATERIALS AND METHOD: ICR mice were superovulated with PMSG/hCG and 1-cell stage mouse embryos were recruited. 1-cell mouse embryo were cocultured on human oviductal cells in a CO2 incubator (coculture group) and were cultured on 0.4% BSA+HTF media (control group). And anti-hLIF Ab was added the cocultured group in a different concentration (1pg, 10pg, 100pg, 1ng) and developmental rate was compaired to the control group, and rhLIF was added to the preincubated 0.4% BSA+HTF media in a different concentration (2000U, 1000U, 100U, 10U) and its developmental rate was compaired to group which was cultured on 0.4% BSA+HTF media only. RESULT: 1. The cleavage rate of 2-cell mouse embryo co-cultured with human tubal epithelial cell was significantly higher than that of cultured with media alone (HTF with 0.4% BSA) (p<0.05). 2. When LIF antibody was added to the medium with human tubal epitherlial cell, the mouse embryo could not cleave more than 2-cell in 1 ng of LIF antibody, and less than 1 ng, the cleavage rate was lower than cultured without LIF antibody group(p<0.05). 3. Two cell blocked ICR mouse embryos were developed into four cells under LIF(p<0.05), but no further development was observed. CONCLUSIONS: These results shows that LIF enhances the development of preimplantation embryo, and when rhLIF is applicated in vitro, it has positive effects on the development of early mouse embryo and can help overcoming the two-cell block.
Animals ; Blastocyst* ; Coculture Techniques* ; Embryonic Structures ; Epithelial Cells ; Humans ; Incubators ; Leukemia Inhibitory Factor* ; Leukemia* ; Mice ; Mice, Inbred ICR ; Oviducts

No abstract available.
Dialysis* ; Humans ; Kidney Failure, Chronic* ; Pericarditis*

No abstract available.

No abstract available.
Renal Dialysis*

Recently we have experienced a case of orbital lipoma, which occured in the left eye of a 28year-old Korean female. Decreased visual acuity and proptosis of 12 months duration were her chief complaints prior to her visit to hospital. Visual acuity was 1.2 in the right eye and 0.5 in the left eye, and ocular movement of the left eye was normal. The left eyeball was almost protruded out of the orbit. Affected eyeball was protruded 2.5mm than that of the unaffected with the Hertel exophthalmometer (reading: with a bar reading of 102mm, RE: 12.5mm, LE: 15mm). The intraocular pressure was (S.T)O.D.: 5.0/5.5 approximate value 17.30mmHg, O.S.: 4.5/7.5 approximate value 28.0mmHg. (A.T) O.D.: 16.0mmHg, O.S.: 26.0mmHg. Funduscopic examination of the left eye revealed temporal disk margin thins and excavation. Visual field examination with Goldman perimeter appeared sector defect of the inferior temporal portion. Positive contrast orbitography with 20% Hypaque, irregular large filling defect was noted in the medial upper quadrant of the orbit. A-scan ultrasonography revealed intraorbital space occupying mass of the nasal portion of the orbital apex on primary position through the eyelid. Surgical removal of the left orbital mass was made sucessfully under the general anesthesia. Histopathological study revealed fibrofatty tissue within normal limit of the left orbital mass in the superior nasal portion.
Anesthesia, General ; Diatrizoate ; Exophthalmos ; Eyelids ; Female ; Humans ; Intraocular Pressure ; Lipoma* ; Orbit* ; Ultrasonography ; Visual Acuity ; Visual Fields