1.A case of Fanconi syndrome.
Yong Woon LEE ; In Seok LIM ; Chul Ha KIM
Journal of the Korean Pediatric Society 1993;36(5):737-742
Fanconi syndrome is a complex of renal tubular dysfunction defined by glycosuria without diabetes, generalized aminoaciduria, phosphaturia, bicarbonaturia, uric aciduria, and renal tubular acidosis. It is often associated with hypokalemia, hypophosphatemia, rickets and osteomalacia. We have experienced one case of Fanconi syndrome with chronic tubulointerstitial nephritis. The patient was a 4 year old and his chief complaints were polyuria, polydipsia, and poor weight gain. There were hyperchloremic metabolic acidosis, hypokalemia, glycosuria, generalized aminoaciduria and phosphaturia. We report a case of Fanconi syndrome with brief review of the literatures.
Acidosis
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Acidosis, Renal Tubular
;
Child, Preschool
;
Fanconi Syndrome*
;
Glycosuria
;
Humans
;
Hypokalemia
;
Hypophosphatemia
;
Hypophosphatemia, Familial
;
Nephritis, Interstitial
;
Osteomalacia
;
Polydipsia
;
Polyuria
;
Rickets
;
Weight Gain
2.Comparison of Diagnostic and Post-therapy Radioiodine Scan in Well-Differentiated Thyroid Cancer and the Clinical Outcome.
Seok Mo LEE ; Sang Kyun BAE ; Ha Yong YUM
Korean Journal of Nuclear Medicine 2000;34(1):22-29
PURPOSE: We compared the first postoperative diagnostic and post-therapy scans of patients who received therapeutic doses of I-131, to investigate the difference in clinical outcomes between patients with concordant findings of diagnostic and post-therapy scans and patients with discrepant (more lesions in post-therapy scan) findings. MATERIALS AND METHODS: The first postoperative diagnostic and post-therapy radioiodine scans of one hundred forty three patients with well differentiated thyroid carcinoma were reviewed. Diagnostic scans were obtained following ingestion of 185 MBq of I-131 and post-therapy scans were obtained after therapeutic dose of 3.7~9.3 GBq of I-131. Successful ablation was defined as no radioiodine uptake on diagnostic radioiodine scan and normal range of serum thyroglobulin level (<10 ng/ml) during serum TSH elevation. RESULTS: Discrepant scan findings were noted in 25 (17.5%) patients. Twenty-two patients (15.4%) showed more lesions in post-therapy scan and 3 patients (2.1%) showed stunning effect. Nine (64.3%) of 14 patients with distant metastasis revealed metastatic lesion(s) only on post-therapy scan. Stunning effect was considered as sublethal damage in 1 patient and treatment by a diagnostic dose in 2 patients. Ablation was achieved in 52.4% (75/143) of all patients. Ablation rate and mean cumulative radioiodine dose were not different statistically between concordant and discrepant groups. CONCLUSION: There were 17.5% difference between diagnostic and post-therapy scan findings when using 185 MBq of I-131 as a diagnostic dose. However, 64.3% of distant metastases were revealed only on post-therapy scan. Ablation rate and mean cumulative radioiodine dose were not different statistically between concordant and discrepant groups. The stunning effect was considered as not only sublethal damage but also treatment by a small diagnostic dose of radioiodine.
Eating
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Humans
;
Neoplasm Metastasis
;
Reference Values
;
Thyroglobulin
;
Thyroid Gland*
;
Thyroid Neoplasms*
3.Clinical and statistic analysis of cesarean section.
Ha Bong KIM ; Jong Seok KO ; Myeong Suk LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):1196-1205
No abstract available.
Cesarean Section*
;
Female
;
Pregnancy
4.A Case of 4P-Syndrome.
Hong Kyu LEE ; Sung Sik LEE ; Soon Il LEE ; Young Seok LEE ; Kweon Ha SON
Journal of the Korean Pediatric Society 1988;31(10):1366-1370
No abstract available.
5.Abnormal Imposition of hands as a Possible Cause of Syphilis.
Ha Wook BONG ; Seok June LEE ; Kee Yang CHUNG ; Min Geol LEE ; Jung Bock LEE
Korean Journal of Dermatology 1994;32(3):542-546
Syphilis is a communicahble disease caused by the motile microaerophilic spirochete Treponema pallidum, which is only a netural pathogen for human. Prevalence of syphilis and other sexually transmitted diseases has traditioially fluctuated with changes in sccia, conditions and sexual behavior. Although sexual contact is the main route of transmission, T. pallidum may also be infected through direct contact with syphilitic lesions, blood transfusion, ingestion of menstrual blood or vaginal secretions, or trsnsplacental transemission. Fomites as the means of transfer is only hypothetical and account for very few, if any, infection. Prosectors, blood handlers and laboratory technicians are at risk for accidental inoculation with infected materials. In extremely unusual circumstances, infection by means of contact with a skin lesion and human bite have been reported. We report two cases of eyphilis following the abnormal imposition of hands, which caused unnecessary erosive trauma with fingernails,
Bites, Human
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Blood Transfusion
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Eating
;
Fomites
;
Hand*
;
Humans
;
Laboratory Personnel
;
Nails
;
Prevalence
;
Sexual Behavior
;
Sexually Transmitted Diseases
;
Skin
;
Spirochaetales
;
Syphilis*
;
Treponema pallidum
6.A Case of Fetal Nuchal Cystic Hygroma.
Yung Ha CHOI ; Chung Ok PARK ; Wan Seok PARK ; Tae Hyung LEE ; Sung Ho LEE
Yeungnam University Journal of Medicine 1989;6(1):165-169
Fetal cystic hygroma is a rare congenital malformation of the lymphatic system appearing as a single or multiloculated fluid-filled cavity, most often in the neck. A case of fetal nuchal cystic hygroma was diagnosed by Ultrasonography at 22 weeks of gestation and the diagnosis was confirmed at autopsy. We present the case with a brief review of literature.
Autopsy
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Diagnosis
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Lymphangioma, Cystic*
;
Lymphatic System
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Neck
;
Pregnancy
;
Ultrasonography
7.A Case of Idiopathic Long QT Syndrome with 2:1 Atrioventricular Block.
Kwang In LEE ; Chul Ha KIM ; In Seok LIM ; Dong Keun LEE ; Byoung Hoon YOO
Journal of the Korean Pediatric Society 1995;38(12):1701-1705
No abstract available.
Atrioventricular Block*
;
Long QT Syndrome*
8.Total Ankle Arthroplasty: Report of 6 cases
Mun Kyoo KIM ; Seok Ha LEE ; Seong Jong LEE ; Taik Seon KIM ; Jai Ik SHIM
The Journal of the Korean Orthopaedic Association 1994;29(2):683-689
Ankle arthrodesis has been regarded as a good operative treatment for post traumatic and rheumatoid arthritis of ankle, and ankle arthroplasty has been also developed with several types, from 1970, by Lord & Marotte. Ankle arthroplasty is more functional & less cosmetic troublesome than arthrodesis, and with more developed prosthesis design, more good result will come. The authors operated 6 cases of total ankle arthroplasty for posttraumatic and rheumatoid arthritis of ankle, which were also indications of arthrodesis, and introduce the results and operative problems of ankle arthroplasty.
Ankle
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Arthritis, Rheumatoid
;
Arthrodesis
;
Arthroplasty
;
Prosthesis Design
9.The Therapeutic Effect of Postganglionic Nerve Block for Symptomatic Schmorl Nodule: A Retrospective Case Series
In Seok SON ; Suk Hyun HWANG ; Suk Ha LEE ; Min Seok KANG
Journal of Korean Society of Spine Surgery 2018;25(4):147-153
OBJECTIVES:
We retrospectively evaluated the clinical efficacy of postganglionic nerve block in symptomatic Schmorl nodules (SNs).SUMMARY OF LITERATURE REVIEW: SNs are common lesions that are often asymptomatic. In certain cases, SNs have been reported to cause severe axial back pain, thereby considerably impacting patients' quality of life. No consensus currently exists on the treatment of symptomatic SNs.
MATERIALS AND METHODS:
From October 2015 to October 2017, a total of 21 patients with symptomatic SNs diagnosed by magnetic resonance imaging (MRI) that did not respond to conservative treatment after 4 weeks were included in the study. All patients received postganglionic nerve block. We evaluated effective pain relief (improvement of back pain of more than 50% compared with before the intervention) and functional improvements, assessed by visual analogue scale (VAS) and Oswestry Disability Index scores obtained at 4 hours, 4 weeks, 8 weeks, 3 months, and 6 months after the procedure.
RESULTS:
Symptomatic SNs were more common at the L2-3 level, and the lower end plate was more commonly involved than the upper end plate. Eighteen of the 21 patients (85.7%) showed effective pain relief, and no deterioration was observed within the follow-up period. Throughout the follow-up period, the VAS remained significantly improved compared to before the procedure (p < 0.05). Complications were not reported in any cases.
CONCLUSIONS
Postganglionic nerve block for symptomatic SNs that do not respond to conservative treatment is a non-invasive modality for pain relief.
10.Late-Onset Candida Vertebral Osteomyelitis in Two Young Patients Who Underwent Heart Transplant Surgery
Min Seok KANG ; In Seok SON ; Tae Hoon KIM ; Suk Ha LEE
The Journal of the Korean Orthopaedic Association 2019;54(1):72-77
Candida vertebral osteomyelitis (CVO) is a rare disease that is a complication of intravenous drug use, but recently it has been recognized as mostly an opportunistic infection. Because CVO appears to mimic pyogenic spondylodiscitis in terms of the clinical and radiologic presentations, it is often neglected in a usual clinical setting. The clinical, radiological, and biological characteristics of CVO are often used to make a differential diagnosis with vertebral osteomyelitis from other etiologies. Once an initial proper diagnosis was performed, the treatment relies on the prompt initiation of appropriate pharmacotherapy and serial monitoring of the clinical progress. This paper report late-onset CVO in two young patients who underwent a heart transplant surgery and had postoperative systemic candidiasis. These two cases are a good reminder of the potential of CVO in immunosuppressive patients treated with anti-fungal agents. This paper presents these two cases with a review of the relevant literature.
Candida
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Candidiasis
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Diagnosis
;
Diagnosis, Differential
;
Discitis
;
Drug Therapy
;
Heart Transplantation
;
Heart
;
Humans
;
Opportunistic Infections
;
Osteomyelitis
;
Population Characteristics
;
Rare Diseases