Recombinant trichobakin (TBK) has been subjected to study its capacity in inhibiting the growth of three lines of human cancer cell - epidermoid carcinoma of the mouth (KB), rabdomyo sarcoma (RD-26) and myelo sarcoma (2/0-Ag-14), it has been shown that TBK has inhibited the cancer cells. Myeloma sarcoma cells were inhibited by TBK at the lowest dose (ID50  2.55 microgram/ml). For RD-26 and KB cell lines, ID50 = 7.27microgram and 10.5 microgram/ml respectively. After 2 year preservation, protein recombinant contains almost the same inhibition activity from its original one
Neoplasms ; Therapeutics ; drugs

Green tea is one of the most widely consumed beverages in Vietnam. Polyphenol in green tea possess biological effects such as antitumoral, anticarciogenic, anti-inflammatory and reduce the risk of cardiovascular disease by increasing the plasma antioxidative capacity in human. Lipid peroxidation and oxidative modification of low-density lipoprotein have been implicated in human atherosclersis. Green tea extract with doses of 100 mg, 150 mg/kg body weight/day reduced levels of MDA plasma and injury of aortic atherosclerosis
Atherosclerosis ; Plant Extracts ; Tea

The remedy "Tu vat dao hong" is made up and manufactured at Pharmacy in Army Traditional Medical Institute. The experiment is conducted on healthy rabbits after coagulating endovascular scattered blood in 3 groups (treated group, controlled group, tanakan group). Results: Howell time in all groups were shorted, rabbits died at second week in controlled group; Quick time were also shorted, and rabbits died also at second week; APTT time reduced significantly (p<0.05) when compared with previous experiment. Platelet quantify, fibrinogen quantify, ethanol test were limited. The remedy have good relative effects when compared tanakan standard drug used in same condition
Prescriptions, Drug ; Pharmacy ; Medicine, Traditional

This is a cross sectional study, including quantitative (household survey) and qualitative methods (indept- interview) on 699 people of 157 household living at Cau Giay district. Findings reveal that few people used medical care at the centers (4.3%), the self-medicated rate was highest (42.3%), then the rate of using private services: 27.7% and using services of higher referral levels: 16.7%... Quality and favorable of services, and level of illness... had major influenced to the choices of healthcare services
Health Care Facilities, Manpower, and Services ; Delivery of Health Care ; Medical Staff

This study was carried out on 44 patients with celebrovascular accident (CVA) at Huu Nghi Hospital. Results showed that CVA infarctus particularly happens in the rest time much more than in working time (66.0%). 86.6% of the patients had been started to rehabilitation is less than 10 days after CVA. Average distance of the time from CVA to: help to sit up: 4.59 days, one's self sit up: 8.29 days, help to stand up: 9.55 days, one's self stand up: 10.5 days, help to walk: 10.87 days, one's self walk: 13.26 days
Chronobiology ; Cerebrovascular Accident ; Rehabilitation

Study on 41 pharmaceutical companies in Hanoi city from March 1999 to February 2000. The results: there was an average of 46 pharmaceutical companies of sixteen countries bought the biding documents and about 43% of those companies submitted the bid documents. At each International Competitive Bids, the average of prices of pharmaceutical drugs were correlative with that announced by UNICEF, however, there was still a case of the mean prices of pharmaceutical drugs were higher than that announced by UNICEF. The prices of pharmaceutical drugs were considered lowest, lower than the average of prices of similar products, which were imported into the Vietnam market and announced by UNICEF
Pharmacy ; Pharmaceutical Preparations

Studying the effectiveness of irradiation on bone-marrow, the numbers of leukocyte, erythrocyte, hemoglobin of mice (25 normal mice and 35 mice treated by gamma irradiation with the dose of 600 rad/(100rad/day) (60 Co) showed that: Gamma irradiation reduced total of leucocytes, the number of different leucocytic (lymphocyte, granulocyte, mono and natural killer cells), the ratio of reticulocyte, number of mature erythrocyte and hemoglobin: Total of leucocytes (3,14 ± 1,58 in comparison with 13,45 ± 4,6); monocytes (0,05 ± 0,03 in comparison with 0,26 ± 0,13), lymphocytes (1,66 ± 0,36 in comparison with 6,34 ± 2,84). After gamma irradiation, the number of reticulocyte was 55%, mature erythrocyte was 73% and hemoglobin was 82%
Therapeutics ; Mice

Study on white mices with age of 6-8 weeks, 18-20g body weight. They were divided into 3 groups: group 1 (control group): 30 mices; group 2: mices were immunesuppressed by 200mg cyclophosphamid per one kilogram of body weight, being checked after 5 days of injection; and 300mg cyclophosphamid per one kilogram (200mg on the first day and 100mg on the fifth day) and it was checked after 10 days of injection (group 3). The results: immunesuppressed model implemented by intraperitonial injection of 200mg per one kilogram of body weight checked after 5 days of injeciton. These parameters were used to assign the immune function
Immunosuppressive Agents ; Mice ; Animal Experimentation ; Cyclophosphamide

Heterogenous transplantation of skin was studied on two strains of mice BALB/C and Swiss.The subjects were divided into various groups :normal group, cyclophosphamid (CP) inhibited group, cyclosporin A (CPA) inhibited group, and the group processed with DY1. The onset of reject phenomenon of the graft and the completed reject of the graft in the groups of mice using CP, CPA and DY1 were more delayed in comparing with the controlled subjects. The cell numbers decreased and the percentage of transformed cells also decreased in all groups using CP, CPA and DY1
Skin Transplantation ; Mice ; Cells

The solid dispersion system (SDA) of dihydroartemisinine (DHA) with PEG 400, PEG 1540, PEG 4000, PEG 6000 and Tween 20, cremophor EL, PEG 400 stearate as cocarrier were prepared. the experimental results showed that the release rate of DHA from suppository base was greater than the semi-synthetic triglyceride base and the physico-mixture
Sesquiterpenes ; Suppositories