2.Investigation in related influencing factors of satisfaction degree with nursing in central injection room of our hospital
Chinese Journal of Practical Nursing 2012;28(31):78-79
Objective To understand the influencing factors of satisfaction degree with nursing in our hospital by investigation in satisfaction degree in central injection room.Methods 252 patients were selected in our hospital from January to December 2011 as the research object,questionnaires were used to investigate the patients,and the influencing factors of satisfaction degree of nursing work were analyzed.Results Among the patients who accepted the investigation,patients' satisfaction scores were correlated with the patients' age,education level,income level,inpatient department,hospital stay time and whether they accepted an operation.Conclusions Nursing staff should pay attention to and strengthen the nursing work quality and efficiency,improve the satisfaction degree with nursing of clinical patients.
3.Treatment strategies for relapsed/refractory multiple myeloma
Journal of Leukemia & Lymphoma 2013;22(1):28-31
Multiple myeloma is a malignancy of plasma cells,which is still incurable now.Despite dramatic improvement of the response rate and overall survival have been made due to the application of target therapy and stem cell transplantation,the treatment effect is difficult to maintain,nearly all patients will eventually relapse and become refractory.At relapse,the challenge is to select the appropriate treatment for each patient.The decision will be both disease-dependent and patient-dependent.
4.Analysis on the application of antibiotics in the National Essential Drug List in Obstetric medical institutions of Western Hunan
Chinese Journal of Primary Medicine and Pharmacy 2012;19(3):331-332
Objective To analyze the application of antibiotics in the national essential drug list used by women in obstetric medical institutions at all levels of Western Hunan ( Basic Medical and Health Institutions Part,2009 version).Methods Medical records were reviewed respectively from May,2010 to December,2010.Results The rate of the use of antibiotics in the essential medicines list in township hospitals was more than 50%,which was higher than that of the secondary and tertiary hospitals.Conclusion The management of the use of medicine in the essential medicines list in hospitals at all levels should be strengthened to control the delivery cost.
5.The adjunctive action of enantone in chocolate cyst after laparoscopic surgery
Jing HE ; Jieqiang LU ; Xiaohong HOU ;
Cancer Research and Clinic 2001;0(04):-
Objective To study the action of enantone in chocolate cyst after laparoscopic surgery. Methods To devide the 76 patients into two groups, study group(50 patients, additional enantone after laparoscopic surgery) and the control group (26 patients, only laparoscopic surgery), to analyse their recurrence rate and pregnancy rate. Results The recurrence rate of study group was obviously lower than control group. In the 48 patients with infertility, the pregnancy rate of study group was higher than control group. Conclusions In chocolate cyst after laparoscopic surgery, enantone can decrease the recurrence rate and increase pregnancy rate.
6.Vasodilation Effect and Underlying Mechanism of Active Fraction from Compound Prunella Vulgaris L. in I-solated Thoracic Aorta of Rats
Suyun QUE ; Yiceng LOU ; Jing HOU
China Pharmacist 2015;(6):884-887
Objective:To investigate the vasorelaxant effect of active fraction from compound Prunella vulgaris L. ( AFCP) on the i-solated thoracic aorta of rats and underlying mechanism. Methods:The study was performed with the tension experiment of the isolate rat thoracic aorta. The changes of vascular ring tension were measured by biological signal acquisition and analysis system, and the vasodila-tor effect of AFCP was observed. Results:AFCP(100-500μg·ml-1)could induce significant relaxation in aorta rings pre-contracted by phenylephrine (PE,1 μmol·L-1), and the relaxation effect was significant(75% ±8%) in endothelium-intact aortic and endothelium-denuded aortic. The vasodilatation effect of AFCP was not significantly affected by nitric oxide synthase ( NOS) inhibitor NG-nitro-L-argi-nine( L-NNA) , guanylate cyclase inhibitor MB,potassium channel blocker TEA and glibenclamide. In Ca2+-free bath solutions, AFCP (300 μg·ml-1 ) could shift downward dose-response curve of CaCl2 and significantly reduce the maximum contraction amplitude of PE. Conclusion:AFCP can relax rat aorta rings in a dose-dependent manner, which is endothelium-independent. The mechanism may be re-lated to the inhibition of intracellular calcium release and extracellular calcium flow, and has nothing to do with NO pathway, prostacyclin generation and calcium-activated potassium channels.
7.Clinical characteristics of 254 cases of polypoidal choroidal vasculopathy
Yong TAO ; Jing HOU ; Xiaoxin LI
Chinese Journal of Ocular Fundus Diseases 2012;28(5):441-444
Objective To observe the clinical characteristics of polypoidal choroidal vasculopathy (PCV).Methods Two hundreds fifty-four PCV patients (306 eyes) were enrolled in this study.All the patients were examined for corrected visual acuity (BCVA) testing,slit-lamp microscope,indirect ophthalmoscopy,fundus photography,fluorescein angiography,indocyanine green angiography and optic coherence tomography.Results The patients included 152 males (59.8%) and 102 females (40.2%) ; the age was from 38 to 91 years,with a mean age of (65.4±8.9) years.Bilateral lesions were observed in 52 patients (20.5%) and unilateral lesions were observed in 202 patients (79.5%).BCVA varied from nonlight perception to 1.2.BCVA was lower than <0.1 in 167 eyes (54.6%),≥0.1 but <0.3 in 92 eyes(30.1%) and ≥0.3 in 47 eyes (15.4%).Vitreous hemorrhage was observed in 61 eyes (19.9%).In 202 patients with unilateral PCV lesions,drusen can be observed in the contralateral eyes of 68 patients (33.7%),exudative age-related macular degeneration changes in the contralateral eyes of 24 patients (11.9 %),and central serous chorioretinopathy history was positive in the contralateral eyes in nine patients (4.5%).In 306 eyes,there were 43 eyes (14.1%) with high permeable choroid.PCV lesions located at macula area in 199 eyes (65.0%),under the temporal retinal vascular arcade in 49 eyes (16.0%),and peripapillary in 15 eyes (4.9%).PCV lesion formation was single in 110 eyes (35.9%),cluster in 176 eyes (57.5%),string in three eyes (1.0%),branch in four eyes (1.3%),and both single and cluster polyps in 13 eyes (4.2%).There were 125 eyes (40.8%) with sub-neuroretinal fluid,121 eyes (39.5%) with hemorrhagic pigment epithelium detachment,and 73 eyes (22.9%) with serous pigment epithelium detachment.Conclusion PCV patients have higher bilateral incidence and female prevalence,and lower rate of peripapillary lesions.
8.Critical Values of Neonatal Coagulation in Clinical Practice and the Investigation of Normal Reference Range
Jing BAI ; Xingning HOU ; Haiqin LAN
Journal of Modern Laboratory Medicine 2017;32(1):150-153
s:Objective To investigate the critical value of neonatal coagulation and the normal reference range in clinical prac-tice,and make Value of the formulation of clinical treatment programs and prevention of neonatal blood coagulation disor-ders.Methods Collected neonatal specimens of 350 cases from January to June 2016 in the General Hospital Ningxia Medi-cal University,after birth with in 6h,the parameters of plasma coagulation:activated partial thromboplastin time (APTT), prothrombin time (PT)clotting time (TT)and fibrinogen (FIB).Made statistics and analysis of all critical information to improve the value of the cases after contact with the telephone registration of neonatology,and critical investigation occurred gestational age children value,birth weight,and critical analysis of the proportion of the value of the proj ect,the distribution of the disease,clinical response and so on.Results Compared with adults and children,four indexes of coagulation levels of newborn were significantly different (t=1.66~2.66,P<0.01),as well as preterm group and term group;additional chil-dren with severe and premature birth or low weight occurs critical the possibility of greater value,and the distribution of high APTT and low FIB profile occured in the most critical values,neonatal jaundice and severe pneumonia was a risk factor critical values outbreak.Overall clinical response rate was 33%,the“answer”and“non response group”in children with in-tracranial hemorrhage of digestive and tract,and the diagnosis rate of statistical results was no significance (χ2=36.68/39, P>0.05).The range of personal critical value of the newborn infant was intended to develop:PT(≤8 s and≥30 s),APTT (≤20 s and ≥90 s)and FIB(≤0.6 g/L and ≥10 g/L).Revised “response rate”,clinicians have increased attention com-pared with the previous increase,reducing the false critical value report incidence.Conclusion The indicators of neonatal co-agulation were different from the adults and children.For the establishment of neonatal blood coagulation parameters refer-ence range,on a regular basis to summary on the clinical data of blood coagulation critical value,and contribute to the devel-opment of suitable critical value standard,and improve the clinical comprehensive diagnosis and treatment level.
9.The relationship between cystatin C and glomerular filtration rate in creatinine-blind range elder patients.
Jian LIU ; Yonglun HANG ; Jing HOU
Chinese Journal of Practical Internal Medicine 2002;0(08):-
Objective To explore the relationship bewteen serum cystatin C (Cys-C )and glomerular filtration rate(GFR) in creatinine-blind range elderly patients. Methods From Jan.2002 to Dec.2003,in the Affiliated Hospital of Luzhou Medical College,the study was performed in 86 elderly patients with chronic renal disease.Serum Cys-C was determined by particle-enhanced immunoturbidimetry.Serum creatinine(Scr) was determined by auto-analyzer.Creatinine clearance rate(Ccr) was estimated by CockCroft-Cault formula.For statistical evaluation,linear regression analysis was used. Results Concentration of Cys-C increased in 56 patients(56.1%).When Ccr was higher than 59mL/min,concentration of Cys-C increased in 44.2% patients.Significant positive correlation was observed between Cys-C and Scr( r =0.89, P
10.Comparison of atrial fibrillation inducibility due to electrical stimulation of the extrinsic vs the intrinsic cardiac autonomic innervation
Jing ZHOU ; Yansheng DING ; Yinglong HOU
Chinese Journal of Interventional Cardiology 1996;0(04):-
Objective To investigate the influence of cervical vagosympathetic trunk or ganglionated plexi stimulation to the inducibility of atrial fibrillation(AF) in dogs.Methods In 16 anesthetized dogs,right cervical vagosympathetic trunk(VST) were dissected.A right thoracotomy was used to expose fat pad(FP) containing the ganglionated plexi(GP) at the caudal end of the sinus node.An electrode catheter was attached along the right superior pulmonary vein to allow programmed atrial pacing.At 2?,4? and 10? threshold atrial refractory periods(ARPs) were determined with and without VST or GP stimulation.At each pacing threshold AF inducibility was measured from the window of vulnerability(WOV).A cumulative WOV sum made of all WOVs was calculated in each group.Results In the baseline state the heart rate(HR) averaged 153?22 beats/min.Slowing of the HR by VST stimulation(79?44 beats/min) was not significantly different than with GP induced slowing(87?99 beats/min,P=NS).Furthermore,there were no significant differences between the lowest ARPs with VST stimulation and GP stimulation,accounting to 90?17 ms and 91?13 ms respectively(P=NS),but both are shorter than that in the baseline state,which was 101?20 ms(P