1.Expression of HLA-DR antigen in different histologic types of gastric carcinoma.
Soo Sang SON ; Young Hun KIM ; In Ho KIM ; Eun Sook CHANG ; Sang Pyo KIM
Journal of the Korean Cancer Association 1993;25(6):818-825
No abstract available.
HLA-DR Antigens*
2.Effect of HLA-DR expression on IL_1 production by keratinocytes.
Woo Young SIM ; Jai Kyung PARK ; Choong Rim HAW
Korean Journal of Dermatology 1991;29(6):713-726
No abstract available.
HLA-DR Antigens*
;
Keratinocytes*
3.HLA-DR genotyping from one drop blood by double PCR.
Hoon HAN ; Jung Bin LEE ; Yeun Jun CHUNG ; Byung Uk LIM
Journal of the Korean Society for Microbiology 1991;26(2):205-214
No abstract available.
HLA-DR Antigens*
;
Polymerase Chain Reaction*
4.HLA-DR genotyping from sperm by double PCR.
Hoon HAN ; Byung Uk LIM ; Yeun Jun CHUNG ; Jung Bin LEE
Korean Journal of Immunology 1991;13(1):89-98
No abstract available.
HLA-DR Antigens*
;
Polymerase Chain Reaction*
;
Spermatozoa*
5.Graft-versus-Host Disease: Report of Four Cases.
Jong Yuk YI ; Baik Kee CHO ; Won HOUH ; Chong Won PARK ; Choon Choo KIM
Annals of Dermatology 1989;1(1):21-27
No abstract available.
Graft vs Host Disease*
;
HLA-DR Antigens
6.Abberant expression of HLA-DR antigen in thyroid cancer.
Myung Shik LEE ; Kyung Ja CHO ; Weon Seon HONG ; Chang Min KIM ; Jhin Oh LEE ; Tae Woong KANG
Korean Journal of Immunology 1991;13(2):195-199
No abstract available.
HLA-DR Antigens*
;
Thyroid Gland*
;
Thyroid Neoplasms*
7.Reverse hybridization between non-tailed probes and sample DNA labeled with non-radioactive hapten: a simple and rapid methodrecommended for HLA-DR typing using PCR.
Mun Gan RHYU ; Tai Gyu KIM ; Yeun Jun CHUNG ; Seon Young KIM ; Gum Ryong KIM ; Hoon HAN
Korean Journal of Immunology 1991;13(2):187-194
No abstract available.
DNA*
;
HLA-DR Antigens*
;
Polymerase Chain Reaction*
8.The relationship of HLA-DR and systemic lupus erythematosus
Journal of Practical Medicine 2004;487(9):54-55
Study 87 patients with systemic lupus erythematosus (SLE) treated at National Institute of Demato-Venereology. Among serotypes, prevalence of DR2 in patient group was higher (25.3%). This study, similar to previous studies of Southeast Asia and Asia countries, suggested the relationship of SLE and HLA-DR2, and confirmed again DR2 was a main serotype of HLA-DRB1 locus that determined sensitivity of SLE in Southeast Asia and Asia people.
Lupus Erythematosus, Systemic
;
HLA-DR Antigens
;
Therapeutics
9.HLA-DR typing by PCR-SSP technique
Journal of Practical Medicine 2002;435(11):21-22
Participants of this study were 11 healthy people. Method of amplification for a specific gene fragment in ADN was used. Sample 1 was controlled by PCR-SSO technique in National Laboratory for Histointegration of Saint-Luis Hospital, Paris. Sample 11 was verified by PCR-RFLP in Immunological Laboratory of Department for Microbiology and Immunology, Aichi University, Japan. Result of verification was similar to that of PCR-SSP technique.
Polymerase Chain Reaction
;
HLA-DR Antigens
10.Analysis of Ambiguities of HLA-DR Typing using the Dynal RELI(TM) SSO HLA-DRB Kit and Development of an 'Interpretation Program for Koreans'.
Eun Young SONG ; Sung Keun PARK ; Sun Mee KIM ; Byoung Cheol KIM ; Bok Yeon HAN ; Young Mi LIM ; Myoung Hee PARK
The Korean Journal of Laboratory Medicine 2002;22(4):267-277
BACKGROUND: HLA-DR typing kits using reverse-SSO (sequence specific oligonucleotide) method show considerable ambiguities in HLA-DRB1 generic typing. We analyzed the ambiguities of the Dynal RELI(TM) SSO HLA-DRB test (Dynal DRB test) and developed an 'Interpretation Program for Koreans'. METHODS: A total of 3,000 Koreans were typed for HLA-DRB1/B3/B4/B5 using the 36 probe Dynal DRB test and all of the cases showing ambiguities in HLA-DRB1 generic typing were subjected to confirmatory typing using the PCR-single strand conformation polymorphism (SSCP) method. On the basis of these results, an 'Interpretation Program for Koreans'was developed for the 45 probe Dynal DRB test. RESULTS: Among 3,000 Koreans tested by the 36 probe Dynal DRB test, 456 cases (15.2%) showed ambiguities. In 95% of the ambiguity cases (433/456) and 99.2% of the total cases tested (433/3,000), the'most probable type'could be expected from the DRB1 gene frequencies and DRB1-B3/B4/B5 associations in Koreans and these results were in accordance with the confirmatory typing results as well as the results given by the 'Interpretation Program for Koreans'. Similarly, the 'Most Probable'could be assigned by the program in 99.4% (348/350) of the cases tested with the 45 probe Dynal DRB test. CONCLUSIONS: Ambiguity in the Dynal DRB test was observed in >15% of the Korean samples tested. The majority (95%) of the ambiguities could be resolved on the basis of HLA-DRB1 gene frequencies and DRB1-B3/B4/B5 associations in Koreans. Furthermore, using the program developed in this study, the correct assignment of DRB1 generic types was possible without additional typing in the majority (>99%) of the cases tested.
Dichlororibofuranosylbenzimidazole
;
DNA
;
Gene Frequency
;
HLA-DR Antigens*
;
HLA-DRB1 Chains
Result Analysis
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