3775 pregnant women attending Tu Du maternal hospital in the period 1995-1997 were randomly included in the study. The results showed that, 3 pregnant women (0.1%) had HIV seropositivity, 290 (7.7%) HBsAg positivity, 21 (0.6%) treponema infection. Among 293 sera screened for toxoplasma infection, there were 17 seropositive cases (16%). History of blood transfusion were found to be factors associated with treponema seropositivity by univariable analysis
HIV, Seroepidemiologic Studies ; Hepatitis B ; toxoplasmosis ; Treponemal Infections ; pregnant women

BACKGROUND: The epidemic of human immunodeficiency virus (HIV) or sexually transmitted infections (STIs) is an important public health issue in the worldwide. Therefore, we investigated the trends of the seroprevalence of HIV and, syphilis and the gonorrhea positive rates in Gwangju from 2002 to 2006. MATERIALS AND METHODS: The results of laboratory tests for HIV, syphilis and gonorrhea were collected from five public health centers and 19 hospitals in Gwangju. The number of tested patients from 2002 to 2006 was 348,202 cases for HIV, 80,115 cases for syphilis and, 103,548 cases for gonorrhea. RESULTS: HIV/AIDS infections have rapidly increased at public health centers and hospitals. Especially, most of newly HIV-infected people were patients on ambulatory care/hospitalization, and they were also found via preoperation tests and according to the clinical symptoms. The gonorrhea positive rates have gradually decreased by year while the syphilis infection rates have slightly increased from 2002 to 2006. CONCLUSIONS: We have to determine the reasons why HIV and syphilis infections, but not gonorrhea, have increases simultaneously by the year. These results should be helpful to create a more effective STD prevention policy and the treatment guidelines for the people in Gwangju in the near future.
Gonorrhea ; HIV ; Humans ; Public Health ; Seroepidemiologic Studies ; Syphilis

BACKGROUND: The epidemic of human immunodeficiency virus (HIV) or sexually transmitted infections (STIs) is an important public health issue in the worldwide. Therefore, we investigated the trends of the seroprevalence of HIV and, syphilis and the gonorrhea positive rates in Gwangju from 2002 to 2006. MATERIALS AND METHODS: The results of laboratory tests for HIV, syphilis and gonorrhea were collected from five public health centers and 19 hospitals in Gwangju. The number of tested patients from 2002 to 2006 was 348,202 cases for HIV, 80,115 cases for syphilis and, 103,548 cases for gonorrhea. RESULTS: HIV/AIDS infections have rapidly increased at public health centers and hospitals. Especially, most of newly HIV-infected people were patients on ambulatory care/hospitalization, and they were also found via preoperation tests and according to the clinical symptoms. The gonorrhea positive rates have gradually decreased by year while the syphilis infection rates have slightly increased from 2002 to 2006. CONCLUSIONS: We have to determine the reasons why HIV and syphilis infections, but not gonorrhea, have increases simultaneously by the year. These results should be helpful to create a more effective STD prevention policy and the treatment guidelines for the people in Gwangju in the near future.
Gonorrhea ; HIV ; Humans ; Public Health ; Seroepidemiologic Studies ; Syphilis

To assess the prevalence of HIV infection in patients with sexually-transmitted diseases(STD), we screened STD patients who visited STD clinics in Seoul area during the period of April 1993-Octorber 1993. Blood samples were collected by unlinked anonymous method, and antibodies against HIV were screened. Fi-ve hundred and thirty patients with STD werescreened. Median age of the patients was 23 year. Male to female ratio was 1:2.8. None of the patients had HIV antibody. The prevalence of HIV infection in STD patients was estimated to be less than 5%.
Anonyms and Pseudonyms ; Antibodies ; Female ; HIV Infections* ; HIV* ; Humans ; Male ; Prevalence ; Seoul ; Seroepidemiologic Studies* ; Sexually Transmitted Diseases*

OBJECTIVES: Brucellosis is a systemic disease with a wide spectrum of clinical manifestations. This study aimed to determine the seroprevalence of brucellosis in human immunodeficiency virus (HIV) infected patients in Hamadan Province in the west of Iran. METHODS: A total of 157 HIV-infected patients were screened through standard serological tests, including Wright’s test, Coombs’ Wright test, and 2-mercaptoethanol Brucella agglutination test (2ME test), blood cultures in Castaneda media, and CD4 counting. Data were analyzed using Stata version 11. RESULTS: Wright and Coombs’ Wright tests were carried out, and only 5 (3.2%) patients had positive serological results. However, all patients had negative 2ME results, and blood cultures were negative for Brucella spp. Moreover, patients with positive serology and a mean CD4 count of 355.8 ± 203.11 cells/μL had no clinical manifestations of brucellosis, and, and the other patients had a mean CD4 count of 335.55 ± 261.71 cells/μL. CONCLUSION: Results of this study showed that HIV infection is not a predisposing factor of acquiring brucellosis.
Agglutination Tests ; Brucella ; Brucellosis* ; Causality ; CD4 Lymphocyte Count ; HIV Infections ; HIV* ; Humans* ; Iran* ; Mercaptoethanol ; Seroepidemiologic Studies* ; Serologic Tests

OBJECTIVE: To investigate the status of transfusion-transmissible infection (TTI) among voluntary blood donors in Nanjing in recent five years, in order to provide data support for the recruitment of blood donors and formulation and updating of blood screening strategies. METHODS: HIV/HBV/HCV/TP serological markers were detected by ELISA in 487 120 blood donors in Nanjing from 2016 to 2020. Confirmatory assay was applied in anti-HIV positive samples by Nanjing Municipal Center for Disease Control and Prevention. The prevalence of TTI was calculated and the trend of disease was analyzed under different demographic groups. RESULTS: The total positive rate of TTI in blood donors was 0.49% (2 411/487 120), in which the overall seroprevalence rate of HBsAg, anti-HCV, anti-HIV and anti-TP was 0.23%, 0.09%, 0.01% and 0.16%, respectively. The overall prevalence of HIV and TP remained relatively steady (P>0.05), whereas HBV and HCV decreased year by year (P<0.05). The prevalence of TTI was higher among people with lower education level, high age group and first-time blood donation. CONCLUSION The prevalence of TTI among voluntary blood donors in Nanjing is at a low level from 2016 to 2020, but the risk still exists. The recruitment of regular donors and the improvement of blood screening technology can effectively reduce the risk of TTI.
Blood Donors ; HIV Infections/epidemiology* ; Hepatitis B Surface Antigens ; Humans ; Prevalence ; Seroepidemiologic Studies ; Syphilis ; Volunteers

OBJECTIVETo understand the current epidemic situation and high risk factors of human immunodeficiency virus (HIV) infection among paid blood donors living in Shandong provincial China Comprehensive Response (CARES) Project Areas.

METHODSAll residents between 20 to 60 years old were selected from one or several counties in August 2003.

RESULTSThere were 19 HIV(+) infections among 661 subjects interviewed. HIV prevalence rate among paid blood donors was higher (3.98%) than that of others (0.48%) while HIV prevalence rate was higher in plasma donors (7.24%) than that in both plasma and full blood donors (2.90%). There was no infections identified in full blood donors. Donors who donated blood during 1994 - 1995 had a higher prevalence rate (7.07%) than those who started donation after 1995 and those began donation before 1993 (0.99%). The rate of condom use was lower among paid blood donors (13.72%) than that of others. There was a lower rate of voluntary HIV testing among paid blood donors than that of others.

CONCLUSIONThe main high risk population of HIV infection were paid donors in CARES Project Areas, whose risk factor was plasma donation and were infected mainly before 1995. Both the rate of condom use and HIV testing were all very low, indicating that they knew little on HIV/AIDS and paid less attention to self-proctection. It is necessary to enhance HIV/AIDS health education and behavior intervention on paid blood donors.

Adult ; Blood Donors ; China ; epidemiology ; Female ; HIV Infections ; epidemiology ; HIV Seroprevalence ; HIV-1 ; Humans ; Incidence ; Male ; Middle Aged ; Plasma Exchange ; adverse effects ; Risk Factors ; Seroepidemiologic Studies

BACKGROUND: Cytomegalovirus (CMV) infection is one of the important opportunistic infections in immuno-compromised patients. In Korea, seroprevalence of IgG against CMV is over 95%. Therefore, CMV diseases are expected to be a prevalent opportunistic infection in AIDS patients in Korea. METHODS: We reviewed the medical records of 128 patients with HIV infection who visited the Seoul Na-tional University Hospital during the period from Nov. 1987 to Sep. 1996. All the patients were examined by one ophthalmologist and the diagnosis of CMV retinitis were made by funduscopic findings. Other CMV dise-ases were diagnosed when histopathologic examinations showed the characteristic cytomegalic cells. RESULTS: Median duration of follow-up was 8 (0 ~ 59) months. Eleven CMV diseases were found in 7 patients (5.4%) : 6 patients had retinitis, 2 esophagitis, 1 colitis, 1 pneumonitis, and one patient developed disse-minated infection. Fifteen percent (6/33) of the patients whose CD4 + lymphocyte counts were less than 200/ mm 3 at baseline developed CMV diseases. Out of the 9 cases treated with ganciclovir, 7 improved or were stabi-lized. No patient received maintenance treatment and 3 had relapsed. CONCLUSION: CMV diseases are common opportuni-stic infections in AIDS patients in Korea.
Colitis ; Cytomegalovirus* ; Diagnosis ; Esophagitis ; Follow-Up Studies ; Ganciclovir ; HIV ; HIV Infections ; Humans ; Immunoglobulin G ; Korea ; Lymphocyte Count ; Medical Records ; Opportunistic Infections ; Pneumonia ; Retinitis ; Seoul ; Seroepidemiologic Studies

HHV-8 virus is known to be associated with Kaposi's sarcoma (KS) in HIV seropositive patients and its seroprevalence has geographic difference. In South Korea, incidence of KS is low not only in general population but also in HIV patients compared to other countries. It is speculated that low seroprevalence of HHV-8 has contributed to the low incidence of KS in South Korea. We examined the seroprevalence of anti HHV-8 IgG of HIV seronegative health care workers in one University hospital. Enzyme-linked immunosorbent assay(ELISA) was used for diagnosis. One person (0.6%, 1/164) was seropositive, six were equivocal (3.7%, 6/164) and 157 people were seronegative (95.73%, 157/164). This study revealed that seroprevalence of HHV-8 in general population was low in South Korea. Further studies are needed to be carried out to evaluate the low HHV-8 seroprevalence in Korea.
Delivery of Health Care ; Herpesvirus 8, Human ; HIV ; Humans ; Immunoglobulin G ; Incidence ; Korea ; Republic of Korea ; Sarcoma, Kaposi ; Seroepidemiologic Studies ; Viruses

HHV-8 virus is known to be associated with Kaposi's sarcoma (KS) in HIV seropositive patients and its seroprevalence has geographic difference. In South Korea, incidence of KS is low not only in general population but also in HIV patients compared to other countries. It is speculated that low seroprevalence of HHV-8 has contributed to the low incidence of KS in South Korea. We examined the seroprevalence of anti HHV-8 IgG of HIV seronegative health care workers in one University hospital. Enzyme-linked immunosorbent assay(ELISA) was used for diagnosis. One person (0.6%, 1/164) was seropositive, six were equivocal (3.7%, 6/164) and 157 people were seronegative (95.73%, 157/164). This study revealed that seroprevalence of HHV-8 in general population was low in South Korea. Further studies are needed to be carried out to evaluate the low HHV-8 seroprevalence in Korea.
Delivery of Health Care ; Herpesvirus 8, Human ; HIV ; Humans ; Immunoglobulin G ; Incidence ; Korea ; Republic of Korea ; Sarcoma, Kaposi ; Seroepidemiologic Studies ; Viruses