Dupuytren's contracture is caused by a proliferative fibroplasia of the subcutaneous palmar tissue. It is most common in those of Scandinavian and Celtic origin, although it has rarely been reported in Orientals. Many types of surgery are advocated, all with apparent success. Then operative result of 23 cases of Dupuytren's contracture including seven bilateral involvment was analyzed partial fasciectomy was performed in all cases by one surgeon. Average follow-up period was 18 months. We analyzed the results of the operation, to Honner s classification. Excellent result was obtained in 6 cases(26%), good in 14(61%) fair in 3(13%), and poor in 0(0%). The complication were 8(34%) case as followshematoma 4(17%), stiffness 3(13%), skin necrnsis 1(4%). All patrents were not performed that skin graft and total fasciectomy. The partial fasciectomy is suggested as one of the successful method for the treatment of Dupuytren's contracture.
Classification ; Clinical Study ; Dupuytren Contracture ; Follow-Up Studies ; Methods ; Skin ; Transplants

No abstract available.
Alopecia* ; Minoxidil*

Etretinate(Ro 10-9359), an aromatic analogue of vitamin A acid, has been known to be effective in the treatment of psoriasis, Darier's disease, pityriasis rubra pilaris, ichthyosis, and palmoplantar keratoderma when administered orally. In this experiment, we compared the therapeutic and side effects between a group with high dose therapy(initially 75mg of etretinate a day) and an another group with low dose therapy(initially 40mg of etretinate a day). We also observed whether the pretreatment followed by combined treatment with vitamin E could potentiate the therapeutic effect as well as reduce the side effects of oral etretinate. This experiment comprised 102 moderate to severe psoriatic patients. The following results were obtained from this experiment. 1. Fifty-six among 92 patients(61%) who were treated with etretinate for more than 4 weeks showed good to excellent therapeutic effect. 2 The high dose therapy was more effective, but showed more side effects than low dose therapy. 3 Vitamin E did not potentiate the effect of etretinate. In low dose therapy, the pretreatment followed by combined treatment with vitamin E showed a tendency to reduce the side effects of etretinate.
Acitretin* ; Darier Disease ; Etretinate* ; Humans ; Ichthyosis ; Keratoderma, Palmoplantar ; Pityriasis Rubra Pilaris ; Psoriasis* ; Tretinoin ; Vitamin E* ; Vitamins*