1.Heterotopic Glial Nodule in the Lung of an Anencephaly Patient : An autopsy case.
Hye Joung LEE ; Soo Min KANG ; Gyung Hyuck KO
Korean Journal of Pathology 1991;25(5):457-461
The heterotopic and tissues may be divided into two categories: those that are found in the head and neck region, and those that arise elsewhere. The latter type is rare and most cases are found in the lungs of patients with neural tube defect, particularly anencephaly. Our report descrives anencephalic male infant with heterotopic glial nodules in both lungs. The largest nodule is 2x1.5x1 cm, locates in the lower lobe of the left lung, and has a round gray-white cut surface with cystic spaces. Microscopically, the nodules consist of irregularly arranged astrocytes and glial fibers, in which are embedded gland-like or cystically dilated bronchioles. The astrocytes and glial fibers are strongly positive for glial fibrillary acidic protein and show astrocytic filaments on electron microscopy. This will be an additional case supporting the amniotic fluid aspiration/implantation theory of pathogenetic mechanism of distal heerotopic glial tissue.
Infant
;
Male
;
Female
;
Humans
2.A Study on the Precancerous Lesion of Breast Carcinoma in 9, 10-Dimethyl-1, 2-Benzanthracene-treated Rats.
Cheon Sik CHOI ; Soo Min KANG ; Hye Jung LEE ; Gyung Hyuck KO ; Cheol Keun PARK
Korean Journal of Pathology 1991;25(2):104-113
Following results were obtained from the light microscopic and stereomicroscopic observations of the breasts of rats treated with 9, 10-Dimethyl-1,2-Benzanthracene(DMBA). 1) Adenocarcinomas developed in 17 rats (24%) among 70 DMBA-treated rats. 2) Terminal and buds (TEB) were observed longer in DMBA-treated rats than in control group, but they finally disppeared 4 monthes after treatment. 3) Many hyperplastic alveolar nodules (HAN) developed in DMBA-treated rats. 4) There were no transitional lesions between TEB and adenocarcinoma or HAN and adenocarcinoma. 5) The number of lobules was decreased in DMBA-treated rats. On the other hand, terminal ducts were increased in number. These findings suggest that DMBA stimulate the regression of lobules and induce to form terminal ducts from which adenocarcinomas and HAN develop independently.
Rats
;
Animals
;
Adenocarcinoma
;
Breast Neoplasms
3.Effect of induction chemotherapy in advanced epithelial ovarian cancer.
Tchan Kyu PARK ; Hyung Min CHOI ; Soo Nyung KIM ; Hyeong Soon KIM ; Gyung Soo KIM ; Jeong Yeon KIM
Journal of the Korean Cancer Association 1992;24(5):724-729
No abstract available.
Induction Chemotherapy*
;
Ovarian Neoplasms*
4.Medium Tau Inversion Recovery(MTIR) Sequence for White Matter Suppression in Brain Cortical Lesions.
Gyung Ho CHUNG ; Jeong Min LEE ; Chong Soo KIM
Journal of the Korean Society of Magnetic Resonance in Medicine 1999;3(1):60-65
PURPOSE: The purpose of this study was to evaluate the image quality, contrast characteristics, and possible clinical utility of Medium Tau Invesion Recovery(MTIR) sequence with white matter suppression in patients with brain cortical lesion. MATERIALS AND METHODS: Two normal volunteers and twenty-one patients with cortical lesion were scanned with MTIR as well as other MR imaging sequences. Gray-white matter contrast was evaluated objectively using region-of-interest calculations, including percent contrast and contrast-to-noise ratio(CNR). MTIR sequence was visually compared with other sequences in 21 patients with cortical lesion including conspicuity and detection rate. RESULTS: MTIR sequence had the highest percent contrast and CNR between the gray matter and white matter. In twenty-one cases of cortical lesion including cortical dysplasia, MTIR sequence improved delineation and conspicuity of lesion, but MTIR sequence could not detect new lesions. CONCLUSION: MTIR sequence demonstrated a superior percent contrast and CNR to other MR pulse sequences. The MTIR sequence well delineated the cortical lesions, particularly in including cortical dysplasia. It may be used as an adjunctive imaging sequence in case of poor gray and white matter differentiation with conventional T1-weighted sequences.
Brain*
;
Healthy Volunteers
;
Humans
;
Magnetic Resonance Imaging
;
Malformations of Cortical Development
5.The Therapeutic Effects of Dexamethasone Therapy in Neonate with Bacterial Meningitis.
Eun Gyung LEE ; Kook In PARK ; Min Soo PARK ; Moon Sung PARK ; Ran NAMGUNG ; Chul LEE ; Dong Kwan HAN
Journal of the Korean Pediatric Society 1995;38(5):602-611
No abstract available.
Dexamethasone*
;
Humans
;
Infant, Newborn*
;
Meningitis, Bacterial*
6.Short- & Long-term Effectiveness of Intracavitary Urokinase in Loculated Thoracic Empyema.
Young Min HAN ; Ki Chul CHOI ; Chong Soo KIM ; Gyung Ho CHUNG ; Myung Hee SOHN ; Tae Gon JEONG
Journal of the Korean Radiological Society 1995;32(1):115-119
PURPOSE: The purpose of this study was to evaluate the short- and long-term effectivensess of intracavitary urokinase with percutaneous catheter drainage in Ioculated thoracic empyemas. MATERIALS AND METHODS: 15 patients were identified as second stage of Ioculated thoracic empyema by estimating nature of pleural fluid, chest PA, lateral decubitus view and CT scan. Under the guidance of fluoroscopy or ultrasound, catheter was inserted percutaneously. Instillation of urokinase was started when amount of drained fluid became less than 30ml per day with 100,000U of urokinase mixed with 100ml of normal saline. Trial of urokinase was repeated until complete drainage of empyema was demonstrated on plain chest film obtained after 48 hours. RESULTS: Successful complete drainage was achieved in 14 of 15 patients. In long-term study, complete resorption was demonstrated in 11 of 12 patients. Average dosage of used urokinase was 330,000U and mean duration of catherter insertion was 35 days. CONCLUSION: lntracavitary urokinase with percutaneous catheter drainage is a safe and effective method to facilitate drainage of Ioculated empyema and to prevent recurrence.
Catheters
;
Drainage
;
Empyema
;
Empyema, Pleural*
;
Fluoroscopy
;
Humans
;
Recurrence
;
Thorax
;
Tomography, X-Ray Computed
;
Ultrasonography
;
Urokinase-Type Plasminogen Activator*
7.Short- & Long-term Effectiveness of Intracavitary Urokinase in Loculated Thoracic Empyema.
Young Min HAN ; Ki Chul CHOI ; Chong Soo KIM ; Gyung Ho CHUNG ; Myung Hee SOHN ; Tae Gon JEONG
Journal of the Korean Radiological Society 1995;32(1):115-119
PURPOSE: The purpose of this study was to evaluate the short- and long-term effectivensess of intracavitary urokinase with percutaneous catheter drainage in Ioculated thoracic empyemas. MATERIALS AND METHODS: 15 patients were identified as second stage of Ioculated thoracic empyema by estimating nature of pleural fluid, chest PA, lateral decubitus view and CT scan. Under the guidance of fluoroscopy or ultrasound, catheter was inserted percutaneously. Instillation of urokinase was started when amount of drained fluid became less than 30ml per day with 100,000U of urokinase mixed with 100ml of normal saline. Trial of urokinase was repeated until complete drainage of empyema was demonstrated on plain chest film obtained after 48 hours. RESULTS: Successful complete drainage was achieved in 14 of 15 patients. In long-term study, complete resorption was demonstrated in 11 of 12 patients. Average dosage of used urokinase was 330,000U and mean duration of catherter insertion was 35 days. CONCLUSION: lntracavitary urokinase with percutaneous catheter drainage is a safe and effective method to facilitate drainage of Ioculated empyema and to prevent recurrence.
Catheters
;
Drainage
;
Empyema
;
Empyema, Pleural*
;
Fluoroscopy
;
Humans
;
Recurrence
;
Thorax
;
Tomography, X-Ray Computed
;
Ultrasonography
;
Urokinase-Type Plasminogen Activator*
8.A Histopathological Study on the Estrogen-induced Breast Lesion in Rats.
Gyung Hyuck KO ; Cheol Keun PARK ; Myoung Keun SHIN ; Soo Min KANG ; Hye Jung LEE ; Jeong Hee LEE
Korean Journal of Pathology 1992;26(5):466-475
Forty eight female Sprague-Dawley rats received a subcutaneous implant containing 12.5 mg estradiol ant the age of 3 weeks. Three rats were killed in 1, 2, 3, 4, 6 weeks and in every month during 2~12 months after implantation, and the breasts were examined by light microscope. In all rats, enlargement of terminal end buds was obseved in 1~2 weeks, maximum development of hyperplastic alveolar nodules in 3 weeks, and marked dilatation and secretion of alveoli or ducts in 1~12 months after implantation. Ductal epithelial hyperplasia was observed in 27 rats and carcinomas developed in 23 rats in 2~12 months after implantation. It was thought that the changes induced by estradiol are more similar to the human breast lesions, compared with changes induced by chemical carcinogens such as dimethylbenzanthracene(DMBA), because breast carcinomas developed in close relationship with ductal epithelial hyperplasia in both estradiol-treated rats and humans, but not in DMBA-treated rats.
Female
;
Humans
;
Rats
;
Animals
;
Carcinogens
9.CT findings of sclerosing hemangioma of the lung: Two cases report.
Young Min HAN ; Ho Young SONG ; Gyung Ho CHUNG ; Chong Soo KIM ; Kong Geun LEE ; Ki Chul CHOI
Journal of the Korean Radiological Society 1993;29(1):104-110
Sclerosing hemangiomas are rare benign neoplasms in pulmonary parenchyme, We analyzed CT findings of two cases of sclerosing hemangiomas of the lung in two adult females. Chest radiograph showed well-circumscuribed, round soft tissue mass with calcification in right lower lobe of one patient and without calcification and moderate or marked contrast enhancement was clearly demonstrated with CT scan. CT findings of contratst enhancement and contour of calcification allow differentiation of sclerosing hemangioma from other venign neoplasms or postinflammotory pseudotusrs of the lung.
Adult
;
Female
;
Histiocytoma, Benign Fibrous*
;
Humans
;
Lung
;
Pulmonary Sclerosing Hemangioma*
;
Radiography, Thoracic
;
Tomography, X-Ray Computed
10.Agenesis of the right lobe of liver.
Jeung Min LEE ; Chong Soo KIM ; Soo Hyun CHUNG ; Myung Hee SOHN ; Gyung Ho CHUNG ; Young Min HAN ; Ki Chul CHOI ; Baik Hwan CHO
Journal of the Korean Radiological Society 1993;29(4):805-808
Agenesis of the right lobe of the liver is a rare anomaly which may be associated with stone diseases, portal hypertension, and other congenital anomalies. The radiological differential diagnosis includes lobar atrophy due to cirrhosis or hilar cholangiocarcinoma. We present a case of agenesis of the right lobe of the liver with characteristic clinical and radiological findings.
Atrophy
;
Diagnosis, Differential
;
Fibrosis
;
Hypertension, Portal
;
Klatskin Tumor
;
Liver*