1.The Displaced Bucket-Handle Tear of the Meniscus: MRi Findings.
Young Mi KWON ; Seon Kwan JUHNG ; Jong Jin WON ; Gyung Hi PARK ; Gang Deuk KIM
Journal of the Korean Radiological Society 1994;31(1):145-150
PURPOSE:To describe the features of displaced bucket-handle tears of the menisci on magnetic resonance (MR) images and to assess associated knee injuries. MATERIALS AND METHODS: We retrospectively reviewed coronal and sagittal MR images in 21 bucket-handle tears. The subjects were patients who had underwent preoperative MR evaluations of the knee and were identified from the arthroscopic surgical records as bucket-handle tear. We also described patterns of associated injuries. RESULTS:On coronal MR images, (a) in all cases, peripheral portion of the meniscus(bucket) had the appearance of a truncated or altered wedge;(b) central fragments(handle) were observed to be sitting in the intercondylar notch(16 cases) or located between the fernoral condyle and tibial plateau (5 cases). On sequential sagittal MR images, (c) the bow-tie appearance of the body of the meniscus was not seen (13 cases);(d) the bow-tie appearance of the displaced inner fragment was seen at the intercondylar notch level (9 cases);(e) "double posterior cruciate ligament" sign was presented (7 cases). Associated joint abnormalities included anterior cruciate ligament tears(l 1), contralateral meniscal tears(l 1), posterior cruciate ligament tears(3), medial collateral ligament tears(3), osteoarthritis(1), and Baker's cyst(l). CONCLUSION:Awareness of these characteristic MR findings(a-e) may increase the sensitivity of MR imaging in the diagnosis of displaced bucket-handle tears, and the MRI may be helpful to correctly characterize the displaced fragment and patterns of associated injury, providing arthroscopists a guide to appropriate surgical plans.
Anterior Cruciate Ligament
;
Collateral Ligaments
;
Diagnosis
;
Humans
;
Joints
;
Knee
;
Knee Injuries
;
Magnetic Resonance Imaging*
;
Posterior Cruciate Ligament
;
Retrospective Studies
2.Freeman-Sheldon Syndrome: Difficult Intubation A case report.
Eun Gyung PARK ; Chi Hyo KIM ; Jong Hak KIM ; Choon Hi LEE
Korean Journal of Anesthesiology 1998;34(6):1254-1257
The Freeman-Sheldon syndrome (FSS) is a rare congenital myopathy. Main manifestations are "whistling face", camptodactyly with ulnar deviation of the finger and talipes equinovarus. Myopathic fibrotic circumoral musculature result in microstomia with the characteristic protruding pursed "whistling lip" and mandibular and laryngeal development may also be abnormal. Thus the patients with FSS are expected to difficult intubation and the use of muscle relaxant should not be expected to improve intubating condition. We report a children with the Freeman-Sheldon syndrome who was intubated with fiberoptic laryngoscope and discuss anesthetic consideration.
Child
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Clubfoot
;
Fingers
;
Humans
;
Intubation*
;
Laryngoscopes
;
Microstomia
;
Muscular Diseases
3.Percutaneous catheter drainage of abdominal abscess associated with fistulas.
Byung Suk ROH ; Gyung Hi PARK ; See Sung CHOI ; Chang Guhn KIM ; Jong Jin WON ; Kwon Mook CHEA
Journal of the Korean Radiological Society 1993;29(2):262-267
The authors retrospectively reviewed the efficacy of percutaneous catheter drainage in treatment of abdominal abscess associated with fistulas. One hundred sixty four consecutive patients with abdominal abscesses drained percutaneously since 1985 at department of Radiology, Wonkwang University Hospital were studied. Among these, 13 patients were found to have fistulous communications to the biliary duct, the intestinal tract, or the renal calyx. Eleven patients (85%) were successfully treated without surgical intervention while two patients (15%) needed surgical drainage and fistulectomy. The duration of drainage ranged from 7 days to 9 months. Initial drainage of abdominal abscess was performed in the hospital, but 5 of 13 patients were discharged with a tube in place and were followed up as outpatients. In conclusion, percutaneous catheter drainage is an effective and safe means of treating abdominal abscesses with fistulas.
Abdominal Abscess*
;
Catheters*
;
Drainage*
;
Fistula*
;
Humans
;
Outpatients
;
Retrospective Studies
4.Extension of Sensory Blockade after Thoracic and Lumbar Epidural Administration of a Test dose of Lidocaine.
Eun Gyung PARK ; Jong Hak KIM ; Choon Hi LEE
Korean Journal of Anesthesiology 2000;38(5):805-809
BACKGROUND: The distribution of solutions injected into the epidural space has not been well determined. The aim of this study was to compare the difference in extension of sensory blockade between the thoracic and lumbar regions in epidural analgesia. METHODS: Forty-five female patients scheduled for postoperative pain control were enrolled. In group 1 (n = 22), the Tuohy needle was inserted at T6 10 levels and in group 2 (n = 23), it was inserted at T12 L2 levels. The catheter was introduced 3 4 cm into the epidural space and 3 ml of 1.5% lidocaine with epinephrine (1:200,000) was injected. The extension of sensory anesthesia to loss of cold sensation and pinprick test was measured every 5 minute for 15 minutes. RESULTS: Fifteen minutes after epidural injection, the mean sensory block extension in group 1 (7.8 +/- 2.0 dermatomes) was significantly wider than in group 2 (4.7 +/- 2.2 dermatomes) but cranial and caudad spread of sensory blockade in relation to the puncture level was the same in both groups. CONCLUSION: The mean dose of local anesthetic required for analgesia was smaller in the thoracic region than in the lumbar region.
Analgesia
;
Analgesia, Epidural
;
Anesthesia
;
Catheters
;
Epidural Space
;
Epinephrine
;
Female
;
Humans
;
Injections, Epidural
;
Lidocaine*
;
Lumbosacral Region
;
Needles
;
Pain, Postoperative
;
Punctures
;
Sensation
5.Loss of estrogen receptor-alpha (ER-alpha) and promoter hypermethylation in gastric cancer.
In Sook WOO ; Do Ho MOON ; Seong Hun KIM ; So Hi IM ; Myung Ah LEE ; Jin Hyoung KANG ; Young Seon HONG ; Kyung Shik LEE ; Myung Kyu CHOI ; In Shik CHUNG ; Gyung Shin PARK
Korean Journal of Medicine 2004;66(5):504-512
BACKGROUND: The significance of ER expression and hormone manipulation in gastric cancer is not established. There have been several reports supporting the role of the ER gene as tumor suppressor gene in carcinogenesis. The ER-alpha gene is located on chromosome 6q25.1. Deletions of the long arm of chromosome 6 are common in gastric carcinoma, suggesting the presence of tumor suppressor genes in this region. The proportion of ER-positive gastric cancers ranges between 0% and 67% depending on the method of detection. Epigenetic inactivation might explain the loss of ER-alpha gene expression in gastric cancer. There is no information available regarding the methylation status of the ER-alpha gene promoter region in gastric cancer so far. The aim of this study was to assess the expression of ER-alpha in gastric cancer cell lines and determine whether methylation of the 5' promoter region is associated with loss of ER-alpha expression in gastric cancer. METHODS: We investigated such methylation in 13 gastric cancer cell lines. Western blot analysis, reverse transcription-polymerase chain reaction (PCR), methylation-specific PCR (MS-PCR) and bisulfite sequencing analyses were used. Immunohistochemical staining for the ER-alpha gene was dome for forty-two paraffin embedded tissues from gastric cancer patients. RESULTS: ER-alpha protein was not detected in any cell line, ER-alpha mRNA was expressed in only Kato III cell line. MS-PCR and bisulfite sequencing showed all thirteen gastric cancer cell lines had methylated CpG regions in their ER-alpha gene promoters. Immunohistochemical staining of ER-alpha showed no positivity in any of examined samples. CONCLUSION: Inactivation of ER-alpha gene expression in gastric cancer cell lines appears associated with CpG island methylation near the TGA initiation codon of the ER-alpha gene.
Arm
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Blotting, Western
;
Carcinogenesis
;
Cell Line
;
Chromosomes, Human, Pair 6
;
Codon, Initiator
;
CpG Islands
;
Epigenomics
;
Estrogens*
;
Gene Expression
;
Genes, Tumor Suppressor
;
Humans
;
Methylation
;
Paraffin
;
Polymerase Chain Reaction
;
Promoter Regions, Genetic
;
RNA, Messenger
;
Stomach Neoplasms*