1.Trigger points: clinical implications of digital infrared thermographic imaging.
Oh Jin KWON ; Keun Sik YU ; Yang Gyun LEE
Journal of the Korean Academy of Rehabilitation Medicine 1991;15(4):527-533
No abstract available.
Trigger Points*
2.Studies on the Effect of Vinyl Mulching on Pleurotus Cultivation: Control of Mushroom Diseases on Pleurotus ostreatus (II).
Se Jong OH ; Jeong Sik PARK ; Dong Chul LEE ; Pyung Gyun SHIN
Mycobiology 2003;31(1):50-53
Perforated vinyl mulching technique was performed on oyster mushroom beds for controlling mushroom diseases. Mycelium under vinyl sheets were safely protected from outside undesirable microorganisms. One of two mushroom farms showed 75% of disease incidence, the other 40% and National Institute of Agricultural Science and Technology (NIAST) 13% in the conventional growing method, whereas 12%, 14%, and 5% in the vinyl mulching cultivation method. Waterlogging caused mushroom bed worse, and Trichoderma spp. were infested on the conventional mushroom bed. Disease incidence investigated in other case was 25% to 30% in the conventional growing method, whereas 5 to 9% in the vinyl mulching cultivation method. Yields in conventional method were 6.5 to 7.2 kg/m2 and those in vinyl mulching method were 7.6 to 8.1 kg/m2. So it was suggested that vinyl mulching technique was good for prevention from disease and elevation of productivity.
Agaricales*
;
Efficiency
;
Incidence
;
Mycelium
;
Pleurotus*
;
Trichoderma
3.Circulating Extracellular-Vesicle-Incorporated MicroRNAs as Potential Biomarkers for Ischemic Stroke in Patients With Cancer
Oh Young BANG ; Eun Hee KIM ; Mi Jeong OH ; Jaein YOO ; Gyun Sik OH ; Jong-Won CHUNG ; Woo-Keun SEO ; Gyeong-Moon KIM ; Myung-Ju AHN ; Seong Wook YANG ;
Journal of Stroke 2023;25(2):251-265
Background:
and Purpose This study aimed to evaluate whether extracellular-vesicle-incorporated microRNAs (miRNAs) are potential biomarkers for cancer-related stroke.
Methods:
This cohort study compared patients with active cancer who had embolic stroke of unknown sources (cancer-stroke group) with patients with only cancer, patients with only stroke, and healthy individuals (control groups). The expression profiles of miRNAs encapsulated in plasma exosomes and microvesicles were evaluated using microarray and validated using quantitative real-time polymerase chain reaction. The XENO-QTM miRNA assay technology was used to determine the absolute copy numbers of individual miRNAs in an external validation cohort.
Results:
This study recruited 220 patients, of which 45 had cancer-stroke, 76 were healthy controls, 39 were cancer controls, and 60 were stroke controls. Three miRNAs (miR-205-5p, miR-645, and miR-646) were specifically incorporated into microvesicles in patients with cancer-related stroke, cancer controls, and stroke controls. The area under the receiver operating characteristic curves of these three miRNAs were 0.7692–0.8510 for the differentiation of patients with cancer-stroke from cancer-controls and 0.8077–0.8846 for the differentiation of patients with cancer-stroke from stroke controls. The levels of several miRNAs were elevated in the plasma exosomes of patients with cancer, but were lower than those in plasma microvesicles. An in vivo study showed that systemic injection of miR-205-5p promoted the development of arterial thrombosis and elevation of D-dimer levels.
Conclusion
Stroke due to cancer-related coagulopathy was associated with deregulated expression of miRNAs, particularly microvesicle-incorporated miR-205-5p, miR-645, and miR-646. Further prospective studies of extracellular-vesicle-incorporated miRNAs are required to confirm the diagnostic role of miRNAs in patients with stroke and to screen the roles of miRNAs in patients with cancer.
4.Innervated Cross-Finger Pulp Flap for Reconstruction of the Fingertip.
Nae Ho LEE ; Woo Sik PAE ; Si Gyun ROH ; Kwang Jin OH ; Chung Sang BAE ; Kyung Moo YANG
Archives of Plastic Surgery 2012;39(6):637-642
BACKGROUND: Fingertip injuries involving subtotal or total loss of the digital pulp are common types of hand injuries and require reconstruction that is able to provide stable padding and sensory recovery. There are various techniques used for reconstruction of fingertip injuries, but the most effective method is functionally and aesthetically controversial. Despite some disadvantages, cross-finger pulp flap is a relatively simple procedure without significant complications or requiring special techniques. METHODS: This study included 90 patients with fingertip defects who underwent cross-finger pulp flap between September 1998 and March 2010. In 69 cases, neurorrhaphy was performed between the pulp branch from the proper digital nerve and the recipient's sensory nerve for good sensibility of the injured fingertip. In order to evaluate the outcome of our surgical method, we observed two-point discrimination in the early (3 months) and late (12 to 40 months) postoperative periods. RESULTS: Most of the cases had cosmetically and functionally acceptable outcomes. The average defect size was 1.7x1.5 cm. Sensory return began 3 months after flap application. The two-point discrimination was measured at 4.6 mm (range, 3 to 6 mm) in our method and 7.2 mm (range, 4 to 9 mm) in non-innervated cross-finger pulp flaps. CONCLUSIONS: The innervated cross-finger pulp flap is a safe and reliable procedure for lateral oblique, volar oblique, and transverse fingertip amputations. Our procedure is simple to perform under local anesthesia, and is able to provide both mechanical stability and sensory recovery. We recommend this method for reconstruction of fingertip injuries.
Amputation
;
Anesthesia, Local
;
Discrimination (Psychology)
;
Finger Injuries
;
Hand Injuries
;
Humans
;
Microsurgery
;
Nerve Transfer
;
Subcutaneous Tissue
5.A Comparison of the Local Flap and Skin Graft by Location of Face in Reconstruction after Resection of Facial Skin Cancer.
Kyung Suk LEE ; Jun Oh KIM ; Nam Gyun KIM ; Yoon Jung LEE ; Young Ji PARK ; Jun Sik KIM
Archives of Craniofacial Surgery 2017;18(4):255-260
BACKGROUND: Surgery for reconstruction of defects after surgery should be performed selectively and the many points must be considered. The authors conducted this study to compare the local flap and skin graft by facial location in the reconstruction after resection of facial skin cancer. METHODS: The authors performed the study in patients that had received treatment in Department of Plastic Surgery, Gyeongsang National University. The cases were analyzed according to the reconstruction methods for the defects after surgery, sex, age, tumor site, and tumor size. Additionally, the authors compared differences of aesthetic satisfaction (out of 5 points) of patients in the local flap and skin graft by facial location after resection of facial skin cancer by dividing the face into eight areas. RESULTS: A total of 153 cases were confirmed. The most common facial skin cancer was basal cell carcinoma (56.8%, 87 cases), followed by squamous cell carcinoma (37.2%, 57 cases) and bowen's disease (5.8%, 9 cases). The most common reconstruction method was local flap 119 cases (77.7%), followed by skin graft 34 cases (22.3%). 86 patients answered the questionnaire and mean satisfaction of the local flap and skin graft were 4.3 and 3.5 (p=0.04), respectively, indicating that satisfaction of local flap was significantly high. CONCLUSION: When comparing satisfaction of patients according to results, local flap shows excellent effects in functional and cosmetic aspects would be able to provide excellent results rather than using a skin graft with poor touch and tone compared to the surrounding normal skin.
Bowen's Disease
;
Carcinoma, Basal Cell
;
Carcinoma, Squamous Cell
;
Humans
;
Methods
;
Skin Neoplasms*
;
Skin Transplantation
;
Skin*
;
Surgery, Plastic
;
Transplants*
;
Treatment Outcome
6.A Functioning Adrenocortical Oncocytoma.
Woo Seok OH ; Jae Wook CHUNG ; Joon Beom KWON ; Tae Gyun KWON ; Jeong Sik KIM ; Gil Sook YOON
Korean Journal of Urology 2009;50(4):401-403
Adrenocortical oncocytomas are exceptionally rare and most are benign and nonfunctioning. Only 3 cases of adrenal oncocytomas have been reported in the Korean literature and all of them were nonfunctioning. Herein, we report a case of a functioning adrenocortical oncocytoma in a 49-year-old man who presented with Cushing syndrome.
Adenoma, Oxyphilic
;
Cushing Syndrome
;
Humans
;
Middle Aged
7.Cutaneous Leiomyosarcoma of the Face.
Nam Gyun KIM ; Jun Oh KIM ; Young Ji PARK ; Jun Sik KIM ; Yoon Jung LEE ; Kyung Suk LEE
Archives of Craniofacial Surgery 2017;18(2):145-148
Cutaneous leiomyosarcoma is an uncommon superficial soft tissue sarcoma and mainly found in the middle aged to elderly males. It can occur in any part of the body, mostly affecting the extremities and rarely affecting the face. It grows relatively slowly, can be diagnosed by biopsy and is treated by surgical excision. It needs to be distinguished from other spindle cell neoplasms, and immunohistochemical markers are usually required to attain an accurate diagnosis. We report a case of cutaneous leiomyosarcoma appeared on the left cheek within 6 month of a 73-year-old female patient suspected with malignant melanoma before surgery.
Aged
;
Biopsy
;
Cheek
;
Diagnosis
;
Extremities
;
Female
;
Humans
;
Leiomyosarcoma*
;
Male
;
Melanoma
;
Middle Aged
;
Sarcoma
8.Cutaneous Basal Cell Carcinoma Arising in Odontogenic Cutaneous Fistula.
Nam Gyun KIM ; Jun Oh KIM ; Young Ji PARK ; Jun Sik KIM ; Yoon Jung LEE ; Kyung Suk LEE
Archives of Craniofacial Surgery 2017;18(2):141-144
An odontogenic cutaneous fistula is a pathological communication between the outer skin surface of the face and the oral cavity. Facial cutaneous fistula is a complication of odontogenic infection that is often misdiagnosed with skin infection. We report a rare case, which was diagnosed as basal cell carcinoma based on the biopsy of skin lesions in the patient who had been diagnosed with odontogenic cutaneous fistula. A 64-year-old male patient presented with a cutaneous odontogenic fistula. The patient had undergone surgical extraction of fistula tract and loose tooth before dermatology or plastic surgery consultation. With the biopsy and computed tomography, it was confirmed that fistula and basal cell carcinoma. However, the connection between the fistula and skin cancer was not clear. Positron emission tomography-computed tomography scan was performed and was not detected as other local or distant metastasis. After that, wide excision of the skin lesion was performed. Although skin cancer is not commonly observed, it is necessary to rule out this disease entity by performing biopsy of skin lesions.
Biopsy
;
Carcinoma, Basal Cell*
;
Cutaneous Fistula*
;
Dermatology
;
Electrons
;
Fistula
;
Humans
;
Male
;
Middle Aged
;
Mouth
;
Neoplasm Metastasis
;
Skin
;
Skin Neoplasms
;
Surgery, Plastic
;
Tooth
9.Cutaneous Leiomyosarcoma of the Face.
Nam Gyun KIM ; Jun Oh KIM ; Young Ji PARK ; Jun Sik KIM ; Yoon Jung LEE ; Kyung Suk LEE
Archives of Craniofacial Surgery 2017;18(2):145-148
Cutaneous leiomyosarcoma is an uncommon superficial soft tissue sarcoma and mainly found in the middle aged to elderly males. It can occur in any part of the body, mostly affecting the extremities and rarely affecting the face. It grows relatively slowly, can be diagnosed by biopsy and is treated by surgical excision. It needs to be distinguished from other spindle cell neoplasms, and immunohistochemical markers are usually required to attain an accurate diagnosis. We report a case of cutaneous leiomyosarcoma appeared on the left cheek within 6 month of a 73-year-old female patient suspected with malignant melanoma before surgery.
Aged
;
Biopsy
;
Cheek
;
Diagnosis
;
Extremities
;
Female
;
Humans
;
Leiomyosarcoma*
;
Male
;
Melanoma
;
Middle Aged
;
Sarcoma
10.Cutaneous Basal Cell Carcinoma Arising in Odontogenic Cutaneous Fistula.
Nam Gyun KIM ; Jun Oh KIM ; Young Ji PARK ; Jun Sik KIM ; Yoon Jung LEE ; Kyung Suk LEE
Archives of Craniofacial Surgery 2017;18(2):141-144
An odontogenic cutaneous fistula is a pathological communication between the outer skin surface of the face and the oral cavity. Facial cutaneous fistula is a complication of odontogenic infection that is often misdiagnosed with skin infection. We report a rare case, which was diagnosed as basal cell carcinoma based on the biopsy of skin lesions in the patient who had been diagnosed with odontogenic cutaneous fistula. A 64-year-old male patient presented with a cutaneous odontogenic fistula. The patient had undergone surgical extraction of fistula tract and loose tooth before dermatology or plastic surgery consultation. With the biopsy and computed tomography, it was confirmed that fistula and basal cell carcinoma. However, the connection between the fistula and skin cancer was not clear. Positron emission tomography-computed tomography scan was performed and was not detected as other local or distant metastasis. After that, wide excision of the skin lesion was performed. Although skin cancer is not commonly observed, it is necessary to rule out this disease entity by performing biopsy of skin lesions.
Biopsy
;
Carcinoma, Basal Cell*
;
Cutaneous Fistula*
;
Dermatology
;
Electrons
;
Fistula
;
Humans
;
Male
;
Middle Aged
;
Mouth
;
Neoplasm Metastasis
;
Skin
;
Skin Neoplasms
;
Surgery, Plastic
;
Tooth