1.Fetal and preterm infant microbiomes: a new perspective of necrotizing enterocolitis.
Korean Journal of Pediatrics 2017;60(10):307-311
Necrotizing enterocolitis (NEC) is a devastating condition of hospitalized preterm infants. Numerous studies have attempted to identify the cause of NEC by examining the immunological features associated with pathogenic microorganisms. No single organism has proven responsible for the disease; however, immunological studies are now focused on the microbiome. Recent research has investigated the numerous bacterial species residing in the body and their role in diseases in preterm infants. The timing of initial microbial colonization is a subject of interest. The microbiome appears to transfer from the mother to the newborn, as well as to the fetus. Cross-talk between the fetus and fetal microbiome takes place continuously to generate a unique immune system. This review examined the transfer of the microbiome to the human fetus, and its potential relationship with NEC.
Colon
;
Enterocolitis, Necrotizing*
;
Fetus
;
Humans
;
Immune System
;
Infant, Newborn
;
Infant, Premature*
;
Microbiota*
;
Mothers
2.A Case of Hereditary Spherocytosis.
Eui Lim CHOI ; Chul Hwan PARK ; Tae Gyu HWANG ; In Soon PARK ; Soon Yong LEE
Journal of the Korean Pediatric Society 1983;26(11):1120-1124
No abstract available.
3.Diagnosis of Budd-Chiari Syndrome by Measuring the Diameter of Azygos-hemiazygos Vein on CT.
Moon Gyu LEE ; Yong Ho AUH ; Cheol Min PARK ; Gi Young KO ; Sang Hee CHOI
Journal of the Korean Radiological Society 1995;32(5):763-767
PURPOSE: The diagnosis of Budd-Chiari syndrome on CT is difficult if CT do not demonstrate obstruction of the IVC or hepatic vein and other parameter is needed for the correct diagnosis. The purpose of our study was to determine the usefulness of measuring the diameter of azygos-hemiazygos vein on CT to differentiate Budd-Chiari syndrome from advanced liver cirrhosis. MATERIALS AND METHODS: Fourteen patients who were proven as Budd-Chiari syndrome on vena cavography were studied for analysis. All patients showed evidence of liver cirrhosis on CT. As a control group fifteen cases of advanced liver cirrhosis who underwent endoscopic sclerotheraphy due to esophageal variceal bleeding were also included for comparison. The largest short axis diameter of azygos-hemiazygos vein was measured in all patients at the level of diaphragm on axial CT and the results were compared in both groups. RESULTS: In patients with Budd-Chiari syndrome the largest short axial diameter of azygos-hemiazygos vein ranged from 0.5cm to 2.5cm(mean ;1.5cm). Only one patient who showed hepatic venous obstruction demonstrated a diameter of less than 1 cm(0. Scm). In contrast, the diameter in patients with advanced liver cirrhosis without obstruction of IVC or hepatic vein was less than 1 cm with a range from 0.2cm to 1 cm(mean ;0.6cm). CONCLUSION: The short axis diameter of azygos-hemiazygos vein was an indicator of IVC obstruction (Budd-Chiari syndrome).
Axis, Cervical Vertebra
;
Budd-Chiari Syndrome*
;
Diagnosis*
;
Diaphragm
;
Esophageal and Gastric Varices
;
Hepatic Veins
;
Humans
;
Liver Cirrhosis
;
Veins*
4.Acupuncture needles in the abdominal organs: features on plain radiography, US and CT.
Seung Yon BAEK ; Moon Gyu LEE ; Hye Young CHOI ; Kyoung Sik CHO ; Yong Ho AUH
Journal of the Korean Radiological Society 1992;28(4):589-592
Acupuncture with gold needle insertion is utilized in Oriental medicine, and the effect of therapy is represented by anti-inflammatory and analgesic function, But sometimes the needle is erroneously inserted into abdominal organs, and then it may cause dangerous complications. We report a case of multiple gold needles in the abdominal organs without having definete clinical symptoms.
Acupuncture*
;
Medicine, East Asian Traditional
;
Needles*
;
Radiography*
5.Purification of the Protective Antigen from Bacillus anthracis.
Jeung Moon PARK ; Yong Keel CHOI ; Seong Kun CHO ; Young Gyu CHAI ; Seong Joo KIM
Journal of the Korean Society for Microbiology 1998;33(6):589-594
Anthrax toxin consists of three separate proteins, protective antigen (PA), edema factor (EF), and lethal factor (LF). PA binds to the receptor on mammalian cells and facilitates translocation of EF or LF into its cytosol. PA is the primary component of anthrax vaccines. In this study we purified PA from culture filtrates of Bacillus anthracis. The purification involved sequential chromatography through hydroxylapatite, DEAE-Sepharose CL-4B, followed by Mono-Q. The purified PA was judged to be homogeneous on SDS-PAGE, and consisted of a single polypeptide chain with a relative molecular weight of 85,000.
Anthrax
;
Anthrax Vaccines
;
Bacillus anthracis*
;
Bacillus*
;
Chromatography
;
Cytosol
;
Durapatite
;
Edema
;
Electrophoresis, Polyacrylamide Gel
;
Molecular Weight
6.Stomach cnacer with ureteral metastasis: CT findings and mode of metastasis.
Hye Young CHOI ; Kyoung Sik CHO ; Moon Gyu LEE ; Yong Ho AUH
Journal of the Korean Radiological Society 1992;28(3):407-412
No abstract available in English.
Neoplasm Metastasis*
;
Stomach*
;
Ureter*
7.A Case of Intracranial Mycotic Aneurysm due to Aspergillus species.
Hyeon Yong CHOI ; Yong Cheol LIM ; Jae Gyu KANG
Korean Journal of Cerebrovascular Surgery 2010;12(3):123-125
Intracranial mycotic aneurysms due to Aspergillus species are extremely uncommon but fatal. A medium-sized ruptured intracranial aneurysm at the middle cerebral artery bifurcation was identified in a 50-year-old female patient. Proper microsurgical clipping was not feasible due to the aneurysm's friable nature. Microsuture and wrapping were done instead. Histological findings confirmed a mycotic aneurysm caused by Aspergillus. Herein, we report on the clinical course and histopathological findings with a relevant literature review.
Aneurysm, Infected
;
Aspergillus
;
Female
;
Humans
;
Intracranial Aneurysm
;
Middle Aged
;
Middle Cerebral Artery
;
Subarachnoid Hemorrhage
8.Short-term Clinical Outcomes after Flanged Intrascleral Fixation of Intraocular Lenses Using Oblique Intrascleral Tunnels
Hyeon Gyu CHOI ; Yong-Kyu KIM ; Sung Pyo PARK ; Yong Dae KIM
Journal of the Korean Ophthalmological Society 2023;64(7):557-565
Purpose:
To report the short-term clinical outcomes after intrascleral fixation of intraocular lenses (IOLs) using oblique intrascleral tunnels.
Methods:
We retrospectively studied 17 patients (18 eyes) who underwent flanged intrascleral IOL fixation from October 2019 to October 2021. The patients were divided into those who underwent fixation using horizontal (group A) and oblique (group B) intrascleral tunnels. We compared the best-corrected visual acuities (BCVAs), cylindrical powers, refractive errors (the differences between the targeted spherical equivalents [SEs] and postoperative SEs) before and 3 months after surgery, and operating times.
Results:
At 3 months vs. preoperatively, there were no significant differences in BCVA (-0.83 ± 0.43 vs. -0.48 ± 0.59), refractive error (-0.06 ± 0.97 diopter [D] vs. -0.05 ± 0.80 D), cylindrical power (-0.42 ± 3.81 D vs. -0.33 ± 1.20 D), or operating time (83.33 ± 28.05 minutes [min] vs. 66.33 ± 20.57 min) between groups A and B, respectively.
Conclusions
In terms of the short-term clinical outcomes after use of horizontal and oblique intrascleral tunnels, we found no significant differences in any parameters studied. However, use of an oblique intrascleral tunnel may shorten the operating time.
9.A Case of Colonoscopically Removed Granular Cell Tumor in the Ascending Colon.
Jae Kyung CHOI ; Myoung Gyu CHOI ; Kyu Yong CHOI ; In Sik CHUNG ; Sang Bok CHA ; Kyu Won CHUNG ; Hee Sik SUN ; Boo Sung KIM ; Young Jin CHOI ; An Hee LEE
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):383-386
This case report describes a patient with semipedunclated granuylar cell tumor(granular cell myoblastoma) of the proximal ascending colon removed by endoscopic polypectomy. A 39-year old femalie was visited to our hospital for intermittent abdominal pain and loose stool. Colonoscopic examination showed a semipedunclated lesion covered with yellowish white smooth mucosa in the proximal ascending colon. The tumor was removed by endoscopic polypectomy. The collected specimen was 0.9x0.8 cm in size. The cut surface of the specimen showed a white round firm tumor covered with mormal epithelium of the colon. Using immunohistochemical study, the tumor cells were to be positively stained by S-100 protein and negatively stained by desmin, which supports the concept of the Schwann cell origin of granular cell tumor. In Korea, 2 cases of granular cell tumor of the colon and rectum, which were treated by surgical removal, have been reported. This case in the first endoscopic polypectomy of granular cell tumor of the colon and retum in Korea. The endoscopic polypectomy is thought to be useful for the therapy of small pedunclated or semipedunclated granular cell tumor, intracolonic type.
Abdominal Pain
;
Adult
;
Colon
;
Colon, Ascending*
;
Desmin
;
Epithelium
;
Granular Cell Tumor*
;
Humans
;
Korea
;
Mucous Membrane
;
Rectum
;
S100 Proteins
10.A Case of Internalization of Thracoamniotic Shunt of Fatal Bilateral Chylothorax.
Soo Pyung KIM ; Jong Chul SHIN ; Sa Jin KIM ; Seung Hye RHO ; Gui Se Ra LEE ; Seung Gyu SONG ; Yong Suk LEE ; Hae Gyu LEE ; Yoon Kyung CHOI
Korean Journal of Perinatology 1998;9(4):429-433
Using 3D ultrasound, bilateral chylothorax was diagnosed antenatally in the second trimester. Apparently stable, bilateral pleural effusion progressed rapidly to severe hydrops with facial edema during observation, and then we decided bilateral pleural-amniotic shunt operation. Here we present a case where drainage of pleural effusion by a double reverse pig tail stent made by ourself was achieved, although placement of the thoracoamniotic shunt resulted in near complete drainage of bilateral pleural effusion with normalization of intrathoracic anatomic relationships, subsequent resolution of fetal hydrops, but the ultimate outcome was unsuccessful due to the internalization of one catheter and unknown sudden death. We think that ongoing research is required to further evaluation about complications associated with this procedure, specifically failure of function due to obstruction, migration of the catheter,
Catheters
;
Chylothorax*
;
Death, Sudden
;
Drainage
;
Edema
;
Female
;
Humans
;
Hydrops Fetalis
;
Pleural Effusion
;
Pregnancy
;
Pregnancy Trimester, Second
;
Stents
;
Tail
;
Ultrasonography