1.Mediastinal Lipoblastoma in a Child: A Case Report.
Young Seob AHN ; Jong Chul KIM ; Gyu Sang SONG
Journal of the Korean Radiological Society 2001;44(3):381-384
Lipoblastoma is a benign tumor which frequently arises in the limbs but rarely in the mediastinum, and is common in children under the age of three years. We report a case of mediastinal lipoblastoma in a 27-month-old female child complaining of dyspnea. Plain radiography demonstrated a huge well-defined mass in the me-diastinum, while CT scanning revealed a soft tissue mass with an internal hypodense portion. When radi-ographic images in children under the age of three reveal a soft tissue mass with a fat component in the mediastinum, especially where there is no calcification or a cystic component, lipoblastoma should be included in the differential diagnosis.
Child*
;
Child, Preschool
;
Diagnosis, Differential
;
Dyspnea
;
Extremities
;
Female
;
Humans
;
Lipoblastoma*
;
Mediastinum
;
Radiography
;
Tomography, X-Ray Computed
2.Occult Hepatitis B Virus Infection: Transmission and Reactivation.
Sang Hee SONG ; Seong Gyu HWANG
The Korean Journal of Gastroenterology 2013;62(3):148-153
Occult HBV infection (OBI) is defined as presence of HBV DNA in the liver tissue in patients with serologically undetectable HBsAg. There are differences in virologic and serological profiles of OBI. Majority of OBI are positive for anti-HBs and/or anti-HBc and minor portion are negative for all HBV markers. However, there are no HBV mutations in the surface and its regulatory regions. HBV infection persists by the presence of covalently closed circular DNA (cccDNA) within the infected hepatocytes, which serves as a reservoir for future infection. OBI increases the risk of HBV transmission through transfusion, hemodialysis, and organ transplantation. Therefore effective measures should be employed to screen OBI. Antiviral therapy is needed in HBsAg-negative transplant patients who are anti-HBc positive to prevent the recurrence of HBV infection. Since HBV replication is strongly suppressed by immune surveillance system in OBI patients, immunosuppression results in massive HBV replication. This leads to acute hepatitis and sometimes mortality when immune surveillance is recovered after stopping immunosuppressive drugs/anticancer chemotherapy. Therefore, narrow surveillance is required to recognize the viral reactivation and start antiviral agents during immunosuppressive therapy/anticancer chemotherapy in patients with OBI.
Blood Transfusion
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DNA, Viral/analysis
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Hepatitis B/*diagnosis/transmission
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Hepatitis B Core Antigens/immunology
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Hepatitis B virus/genetics/*physiology
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Humans
;
Liver Transplantation
;
Renal Dialysis
;
Virus Activation
3.A Case of Endometriosis in the Abdominal Subcutaneous Tissue.
Hyun Ju MOON ; Tae Gyu AHN ; Kyung LEE ; Hyoung Gyun ROH ; Sang Joon CHOI ; Chang Hoon SONG ; Hyuk JUNG
Korean Journal of Obstetrics and Gynecology 1999;42(3):641-645
the ineidence of abdominal subcutaneous endometriosis is quite rare we have experienced one case of subcutaneous endometriosis. The typical clinical bistory and local findings of endometriasis enabk us to make the conect diagnosis. the treatment of choice is complete surgical excision of endometrial tissue and post operative medical therapy. This case was reported with a brief review of the comcemed literatures.
Diagnosis
;
Endometriosis*
;
Female
;
Subcutaneous Tissue*
4.The detection of anti-ENA antibodies in systemic rheumatic diseases.
Sang Cheol BAE ; Gwan Gyu SONG ; In Hong LEE ; Dae Hyun YOO ; Seong Yoon KIM ; Think You KIM
Korean Journal of Medicine 1993;45(4):422-436
No abstract available.
Antibodies*
;
Rheumatic Diseases*
5.A Case of Peripartum Cardiomyopathy.
Sang Bum HA ; Yong Suk CHOI ; Jong Oh KIM ; Seong Lim LEE ; Seung Gyu SONG ; Bong Choon JO
Korean Journal of Perinatology 2001;12(3):384-387
No abstract available.
Cardiomyopathies*
;
Peripartum Period*
6.Cystic Teratoma of the Sacrococcygeal Region in Adult: A Case Report.
Jong Myeong YANG ; June Sik CHO ; Kyung Sook SHIN ; Gyu Sang SONG
Journal of the Korean Radiological Society 2001;45(3):301-304
Sacrococcygeal teratoma is the most common solid tumor to occur in neonates, in whom it mostly takes the form of an obvious exophytic mass. They are, however, rarely found in adults. We report the CT and histopathologic findings of an adult cystic teratoma arising from the lower sacrococcygeal region that was discovered incidentally. Unenhanced CT scans showed an oval-shaped, cystic lesion with hyperattenuating content and no contrast enhancement. After surgery, the gross specimen was seen to be a cystic lesion filled with mucin. Microscopy revealed three germ cell layers in the cystic wall and the lesion was confirmed as cystic teratoma.
Adult*
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Germ Cells
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Humans
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Infant, Newborn
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Microscopy
;
Mucins
;
Sacrococcygeal Region*
;
Teratoma*
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Tomography, X-Ray Computed
7.Comparative Study of Anti-HCV by New HCV EIA, Immunoblotting and RT-PCR in Korean Blood Donors.
Sang Jin EUN ; Jang Soo SUH ; Won Kil LEE ; Jay Sik KIM ; In Soo KIM ; Jong Gyu KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1994;5(1):9-16
A newly developed third generation enzyme immunoassay(Lucky HCD 3.0 EIA) for hepatitis C virus(HCV) antibodies was added with the envelope(E1E2)/NS4 fusion proteins and expanded NS5 proteins as well as the core/NS3 fusion proteins. Authors evaluated the HCD 3.0 EIA with the previously available second generation EIA(HCD 2.0) in 10,435 Red Cross blood donors. Among 10,435 donors who were screened for the presence of HCV antibodies by HCD 2.0 assay, 22(0.21%) sera were repeatedly reactive. All of these sera were tested for further testing. Only 13 of all tested sera were reactive by HCD 3.0 EIA, and nine sera were not reactive. Nine of 13 HCD 3.0 positive sera were reactive by recombinant immunoblot assay(Lucky-Confirm). Also seven of these 13 sera had detectable HCV genomic RNA by reverse transcriptase-polymerase chain reaction(RT-PCR). None of nine HCD 3.0 negative samples had detectable immunoblot assay and HCV genomic RNA. It is concluded that the new HCV EIA can decrease a significant false positivity of second generation EIA in a blood donor population. This new assay correlates well with detection of HCV-RNA by RT-PCR and identifies donors who are truly infected.
Antibodies
;
Blood Donors*
;
Hepatitis C
;
Hepatitis C Antibodies
;
Humans
;
Immunoblotting*
;
Red Cross
;
RNA
;
Tissue Donors
8.A Case of Bleeding Duodenal Varices Confirmed with Intra - operative Endoscopy.
Jong Seo LEE ; Sang Seob YUN ; Eung Kook KIM ; Young Tack SONG ; Sang Yong CHOO ; Jin Mo YANG ; Myung Gyu CHOI ; In Sik CHUNG ; Hee Sik SUN
Korean Journal of Gastrointestinal Endoscopy 1991;11(1):29-32
The bleeding duodenal varices ia uncommon and frequeintly present a difficult diagnostic problem While the bleeding duodenal varices is a complication of portal hypertension, the possibility of bleeding duodenal varices in the absence of eaophageal varix bleeding should be kept mind. For the surgeon, the mikin technical problem is that even when identified by frequently impalpable, and invisible to the naked eye unless they are actively bleeding at the time of surgery. We described simple intra-operative endoscopic technique successfully to identify and bleeding varices in the duodenal third portion prior to the partial duodenal resection. This report summarized our experience and review of literature.
Endoscopy*
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Hemorrhage*
;
Hypertension, Portal
;
Varicose Veins*
9.Pressure Threshold, Grip and Pinch Strength in Female Telephone Operators.
Gyu Han LEE ; Si Bog PARK ; Sang Gun LEE ; Kang Mok LEE ; Sang Chul ROH ; Jaecheol SONG
Journal of the Korean Academy of Rehabilitation Medicine 1997;21(3):589-593
The purpose of this study was to estimate mean pressure thresholds over several skeletal muscles, grip and pinch strengths in female telephone operators. Pressure thresholds on muscles of neck and shoulder were measured with a pressure algometer, and grip and pinch strength were measured with a Jamar dynamometer and a Jamar pinch gauge in 904 female telephone operators. The pressure threshold was highest in the supraspinatus and lowest in the cervical paraspinals. There was no statistically significant difference between right and left corresponding muscles. The mean grip strength was 22.29 kg in the right hand, 21.97 kg in the left hand. The mean tip pinch strength was 0.56 kg in the right, 0.51 kg in the left. The mean lateral pinch strength was 2.21 kg in the right, 2.12 kg in the left. The mean palmar pinch strength was 1.82 kg in the right, 1.66 kg in the left. There was no significant correlation between grip, pinch strength and age(p>0.05). There were positive correlations between height, weight and grip strength. There were positive correlations between exposure duration to visual display terminal and pinch strength.
Cumulative Trauma Disorders
;
Female*
;
Hand
;
Hand Strength*
;
Humans
;
Muscle, Skeletal
;
Muscles
;
Neck
;
Pinch Strength*
;
Shoulder
;
Telephone*
10.Immunohistochemical Detection of p53, erbB-2 and CEA Oncoprotein in Lung Cancer Clinical Correlations.
Seong Su JEONG ; Dong Won KANG ; Gyu Seung LEE ; Dong Seok KO ; Jae Chul SUH ; Geun Hwa KIM ; Kyoung Sang SHIN ; Ju Ock KIM ; Gyu Sang SONG ; Sun Young KIM
Tuberculosis and Respiratory Diseases 1998;45(4):766-775
BACKGROUND: The prognosis of patients with lung cancer is still poor. Lung cancer exhibits a variable clinical outcome, even in those patients with same stage Numerous reports suggest that oncogene expression night play a role in explaining the variability of response and survival But many of these reports are still under debete. So we studied the clinical relevance of oncogene expression in Korean lung cancer patients. lmmunohistochemistry of p53, erbB-2, CEA expression was performed. METHOD: From March, 1992 until March, 1997, 120 patients with lung cancer were reviewed. p53, erbB-2, and CEA expression were detected on paraffin-embedded tumor blocks with the use of monoclonal antibodies. The survival arid response has correlated with the expressibility of p53, erbE-2, arid CEA oncoprotein. RESULTS: Overall, the expression rates of p53 erbB-2, and CEA were 33.7%, 59.3%, and 32.6% respectively. Expression rates were not con-elated to cell type or stage. Compared with response to chemotherapy, no correlation was found. The expression of p53, erbB-2, or CEA was not correlated with 2-year survival. With simultaneous applications of p53. erbB-2, and CEA, patients with 2 or more expressions also did not show poor response to chemotherapy. CONCLUISON: We conclude the p53, erbB-2, and CEA expression are clinically less useful in predicting response to chemotherapy or survival.
Antibodies, Monoclonal
;
Drug Therapy
;
Humans
;
Immunohistochemistry
;
Lung Neoplasms*
;
Lung*
;
Oncogenes
;
Prognosis