No abstract available.
Cesarean Section* ; Endometritis* ; Female ; Pregnancy

Inducible nitric oxide(NO) is understood as a tumoricidal molecule. In animal study, urinary NO excretion after intravesical BCG instillation is recently known. In this study, the authors investigated the pattern of urinary nitrite (stable oxidizide form of nitric oxide) excretion according to the dosage of instilled BCG or number of BCG instillation. According to the dosage of instilled BCG(Pasteur strain :8.l5 x 1000000CFU/mg), 32 Sprauge-Dawley female rats were di-vided into 4 Groups(Group I: control, Group II: BCG1/l0X, Group III: BCGlX. Group IV :BCG10X). Also, each Group was subdivided into a one-time instillation subgroup(one time instillation at the first day) and a six-time instillation subgroup( weekly instillation for six weeks). The urinary nitrite in 24 hours' urine was measured quantitatively in each group by Titertek Multiscan MCC/340 ELISA Reader on an every other day basis after BCG instillation until decreased to control level. Intravesical BCG instillation of the rats led to significant urinary nitrite excretion in Group II (BCG 1/10X:one-time ;30+/-12, six-time ;52+/-6), Group III(BCG 1X,57+/-8, 62+/-2uM/L), Group IV (BCG 10X;65+/-2, 80+/-5uM/L) compared to Group I (control;22+/-4, 21+/-3uM/L) respectively( p<0.05). There was no statistical difference in the increment of urinary nitrite excretion between Group II, Group III and Group IV. The urinary nitrite excretion increased significantly in Group II and Group IV of six-time instillation subgroup compared to one-time instillation subgroup(p <0.05). BCG instillation resulted in significant excretion of urinary nitrite at the first day, which reached peak urinary level at the period of the 3rd to 9th day and the 11th day after instillation in one-time and six-time instillation subgroup respectively. The excretion also remained increased for 33 days and 44 days in two subgroups respectively. The preservation of the urine at -40'C for 4-weeks had no influence on the urinary nitrite concentration. The study demonstrates the pattern of urinary excretion according to the dosage of instilled BCG or number of instillations in addition to disclosing good effects of BCG on the excretion of urinary nitrite in rats. The following can be deduced from this study. Intravesical BCG instillation using only one tenth of the usual dose of which the BCG is used for treatment of superficial bladder tumor, and six-times resulted in effective excretion of urinary nitrite in rats.
Animals ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Mycobacterium bovis* ; Nitric Oxide* ; Rats* ; Urinary Bladder Neoplasms

No abstract available.
Esophageal Achalasia

The authors report a case of superficial femoral arterial trauma caused by external fixator in 53 year-old male patient who had supracondylar fracture of femur due to automobile accident. After removal of external fixator, autogenous bypass graft was perfomed with reversed great saphenous vein. The occlusion of the graft occurred 3 months later, we thought that interposition graft in the chronic inflammatory and fibrotic tissue should be avoided.
Automobiles ; External Fixators ; Femoral Artery ; Femur ; Humans ; Male ; Middle Aged ; Rupture ; Saphenous Vein ; Transplants

Herpes zoster is a disease that causes a skin rash with blisters and extreme pain along mainly the unilateral dermatome. It often occurs in the thoracic nerve area, but can also occur in the cranial, cervical, and lumbar nerve areas. It is not clear that the interventions such as nerve block or subcutaneous local anesthetics result in a lower incidence of postherpetic neuralgia than the natural course of herpes zoster. However, the severity of acute pain is known as a risk factor for postherpetic neuralgia. There have been many studies on the epidural block or paravertebral block for acute pain control of herpes zoster, but superficial cervical plexus block has not been widely applied. We performed a superficial cervical plexus block to alleviate the acute pain of herpes zoster in the neck and obtained the expected result, so we present it with a literature review.

Herpes zoster is a disease that causes a skin rash with blisters and extreme pain along mainly the unilateral dermatome. It often occurs in the thoracic nerve area, but can also occur in the cranial, cervical, and lumbar nerve areas. It is not clear that the interventions such as nerve block or subcutaneous local anesthetics result in a lower incidence of postherpetic neuralgia than the natural course of herpes zoster. However, the severity of acute pain is known as a risk factor for postherpetic neuralgia. There have been many studies on the epidural block or paravertebral block for acute pain control of herpes zoster, but superficial cervical plexus block has not been widely applied. We performed a superficial cervical plexus block to alleviate the acute pain of herpes zoster in the neck and obtained the expected result, so we present it with a literature review.

OBJECTIVE: The aim of this article was investigated whether changes of superoxide dismutase isozymes in the placenta of patients with preeclampsia contribute to radical-induced tissue injury. METHODS: The activities of antioxidant enzymes (superoxide dismutase (SOD), catalase, glutathione peroxidase (GSHPx)) and the contents of thiobarbituric acid reactive substance (TBARS) in the erythrocytes and in the placenta were assayed from 35 women with preclampsia and 35 normotensive pregnant women. RESULTS: The superoxide dismutase (SOD) activities were significantly reduced in the erhtyrocytes and the placenta of patients with pre-eclampsia compared with normotensive pregnant women. The activity of catalase was increased in the erythrocytes of patients with preeclampsia but the statistically significant difference of catalase activity in the placenta and GSHPx activity in both erythrocytes and placenta were not observed. The contents of TBARS were increased significantly in the erythrocytes and placenta of patients with preeclampsia. In preeclamptic placenta, copper and zinc containing superoxide dismutase (CuZn-SOD) was decreased (3.9+/-0.5 vs 5.1+/-0.6 U/mg protein) whereas manganeus containing superoxide dismutase (Mn-SOD) was increased (2.0+/-0.3 vs 2.7+/-0.4 U/mg protein). CONCLUSION: In these results, the decreased CuZn-SOD activity may some roles in increment of TBARS contents in pre-eclamptic placenta and decreased CuZn-SOD activity may be more prone to oxidative stress in the placenta.
Catalase ; Copper ; Erythrocytes ; Female ; Glutathione Peroxidase ; Humans ; Isoenzymes* ; Oxidative Stress ; Placenta* ; Pre-Eclampsia* ; Pregnant Women ; Superoxide Dismutase* ; Superoxides* ; Thiobarbituric Acid Reactive Substances ; Zinc

PURPOSE: The purpose of this study was to assess the clinician satisfaction of a newly introduced around-the-clock radiology coverage system for the emergency department. MATERIALS AND METHODS: Seventeen emergency physicians (8 board certified physicians, 9 residents) were invited to fill out a survey pertaining to the newly introduced radiology coverage system for the emergency department. The questionnaire included 10 questions covering three major topics. The first topic related to the around-the-clock radiology coverage by two full-time radiology residents. The second topic focused on the preliminary interpretations of radiology residents. The last topic included the interpretation assistance system by board-certified radiologists. The answers to each question were assessed using a scoring system of 1 to 5. RESULTS: The mean satisfaction score of the around-the-clock radiology coverage system by the two full-time radiology residents was 4.6 (range 3-5). The mean score for the preliminary interpretation system by the radiology residents was 4.8 (range 4-5). The score for the reliability of the preliminary versus the final interpretations was 4.1 (range 4-5). Lastly, the mean score for the interpretation assistance system by board-certified radiologists was 4.9 (range 4-5). CONCLUSION: The results of this study indicate a high satisfaction rating among clinicians' of the new around-the-clock radiology coverage system for the emergency department.
Emergencies ; Emergency Service, Hospital ; Surveys and Questionnaires

No abstract available.
Carcinoma, Hepatocellular*

Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation. PTLD is the disorder arising from the combined effects of Epstein-Barr virus associated lymphoproliferation with the disruption of the normal immune control of cytotoxic T cells. The only effective treatment of PTLD is often the reduction or elimination of intense immunosuppressive therapy. But we presented here a case of severe acute rejection developed in orthotopic liver transplantation patient after discontinuing the immunosuppression. A 58 year-old male had a liver transplantation for hepatitis B viurs-associated liver cirrhosis and taking cyclosporine postoperatively. He presented two months later with palpable neck mass and abdominal pain. CT scan showed multiple lymphadenopathies in retroperitoneum and more than 3 cm conglomerulated mass in left supraclavicular area. Percutaneous needle biopsy was done in which a this neck mass proved not to be a infectious mononucleosis-like disease or a definite lymphoma. In situ hybridization (ISH) for EBV encoded RNA was positive in a few cell. It suggested a possibility of PTLD, Even though the lymph node is totally necrotic in the given specimen. At that time, the immunosuppression was discontinued, and he was treated with iv gancyclovir. No chemothreapy was administered. Two weeks later, severe acute rejection (RAI=7) followed requiring treatment with steroid pulse. Tacrolimus had replaced cyclosporine and was maintained. Liver function test profile decreased gradually. Serial CT scan showed partial improvement of multiple necrotic lymphadenopathy in the retroperitoneum and supraclavicular area. Two months later, he presented with palpable neck mass and abdominal pain repeatedly. Another incisional biopsy was performed. The results showed B cell lymphoma with CD20 (+), CD3 (-), bcl6 (-), Ki-labelling index 80%, bcl (-), p53 (-). He received 2 courses of cyclophosphamide (600 mg/m2, on day 1 of each course) and prednison (2 mg/kg/day for 5 day). The first 2 courses were given in combination with 4 weekly doses of rituximab (375 mg/m2, i.v). After symptomatic improvement, he was discharged.
Abdominal Pain ; Biopsy ; Biopsy, Needle ; Cyclophosphamide ; Cyclosporine ; Ganciclovir ; Hepatitis B ; Herpesvirus 4, Human ; Humans ; Immunosuppression* ; In Situ Hybridization ; Liver Cirrhosis ; Liver Function Tests ; Liver Transplantation ; Lymph Nodes ; Lymphatic Diseases ; Lymphoma ; Lymphoma, B-Cell ; Lymphoproliferative Disorders* ; Male ; Middle Aged ; Neck ; Organ Transplantation ; RNA ; Rituximab ; T-Lymphocytes ; Tacrolimus ; Tomography, X-Ray Computed ; Transplants