1.A Case of Hereditary Spherocytosis.
Eui Lim CHOI ; Chul Hwan PARK ; Tae Gyu HWANG ; In Soon PARK ; Soon Yong LEE
Journal of the Korean Pediatric Society 1983;26(11):1120-1124
No abstract available.
2.A case of idiopathic rhabdomyolysis in a patient with chronic renal insufficiency.
Soung Soo KIM ; Gyu Taek LIM ; Chul Woo YANG ; Suk Young KIM ; In Seok PARK ; Yoon Sik CHANG ; Byung Kee BANG
Korean Journal of Nephrology 1992;11(2):173-179
No abstract available.
Humans
;
Renal Insufficiency, Chronic*
;
Rhabdomyolysis*
3.Effect of Treatment With Excision of Papillae and Supratarsal Triamcinolone Injection on Refractory Vernal Keratoconjunctivitis.
Won CHOI ; Seong Gyu LIM ; Kyung Chul YOON
Journal of the Korean Ophthalmological Society 2010;51(4):492-497
PURPOSE: To evaluate the therapeutic effect of the combined treatment of excision of the papillae and a supratarsal injection of triamcinolone on refractory vernal keratoconjunctivitis (VKC). METHODS: Twenty-three eyes of 14 patients with refractory vernal keratoconjunctivitis were included. Patients were treated with the combined excision of papillae and supratarsal injection of triamcinolone. Best corrected visual acuity (BCVA), intraocular pressure, symptoms of itching, tearing, discomfort, secretion and epiphora, and signs including limbal hypertrophy, hyperemia, papilla size, keratitis, corneal neovascularization and blepharitis were evaluated before and two weeks, four weeks, and eight weeks after treatment. The CCL11 level in the tears of each eye were analyzed before and two weeks after treatment. RESULTS: The mean scores of subjective symptoms and objective signs as well as BCVA were significantly improved two weeks after treatment. CCL11 levels in the tears were 389.5+/-474.9 pg/ml before treatment and were undetectable two weeks after treatment. Improvement of symptom and sign parameters was maintained up to eight weeks after treatment. However, seven eyes (30.4%) recurred within two weeks after treatment. CONCLUSIONS: Combined excision of the papillae and a supratarsal injection of triamcinolone may be effective in the treatment of refractory VKC.
Blepharitis
;
Conjunctivitis, Allergic
;
Corneal Neovascularization
;
Eye
;
Humans
;
Hyperemia
;
Hypertrophy
;
Intraocular Pressure
;
Keratitis
;
Lacrimal Apparatus Diseases
;
Pruritus
;
Tears
;
Triamcinolone
;
Visual Acuity
4.A Case of Toxic Epidermal Necrolysis Concomittantly Presented with GI Bleeding and Its Gastrofiberscopic Findings.
Na Young KIM ; Kye Heui LEE ; Seon Hee LIM ; Gyu Hyun LEE ; Yong Ju PARK ; Kyung Ju AHN ; Byung Chul LIM ; Joon Woo SHIN
Korean Journal of Gastrointestinal Endoscopy 1996;16(4):608-613
Toxic epidermal necrolysis (T~EN) is a severe mucocutaneous disease characterized by epidermal necrosis possibly extended to the entire body surface and involving multiple internal organs. Digestive tract may be involved too, but there is few report about gastrointestinal lesion in patient with TEN. Recently we experienced a case of TEN with gastrointestinal bleeding in previously healthy 32-year-old woman. The condition developed three days after the initiation of treatment with NSAID and progressed caudally, involving 60 percent of the skin surfaces. During a period of admission gastrointestinal bleeding was noticed. The gastrofiberscopy showed diffuse superficial mucosal lesion with oozing from swollen friable and erythematous mucosa. The skin lesion was progressed inspite of withdrawal of causative agents. The patient was expired due to combined septic shock 10 days later. We report this case with gastrofiberscopic findings and a brief review of literature.
Adult
;
Female
;
Gastrointestinal Tract
;
Hemorrhage*
;
Humans
;
Mucous Membrane
;
Necrosis
;
Shock, Septic
;
Skin
;
Stevens-Johnson Syndrome*
5.Right side fixation of sigmoid colon with a hepato-sigmoidocolic fistula in patient with hepatocellular carcinoma and midgut malrotation.
Nam Gyu CHOI ; Ok In MOON ; Jin Ha KIM ; Sharon LIM ; Sung Chul LIM ; Jun LEE ; Kyung Jong KIM
Journal of the Korean Surgical Society 2013;84(4):256-260
The location of the sigmoid colon varies within the abdominal cavity, but its mesocolon is fixed to the left side. Right side fixation of the sigmoid colon is a very rare congenital positional anomaly. In addition, it has been reported that hepatocolic fistula is also a very rare disease that may present lower gastrointestinal bleeding. Here, the authors describe a case of a 71-year-old man who underwent surgery for hepato-sigmoidocolic fistula complicated by hepatocellular carcinoma and the right side fixation of the sigmoid colon.
Abdominal Cavity
;
Carcinoma, Hepatocellular
;
Colon, Sigmoid
;
Fistula
;
Hemorrhage
;
Humans
;
Mesocolon
;
Rare Diseases
6.Comparison of Inner Retinal Thickness between the Fellow Eyes of Unilateral Branch Retinal Vein Occlusion and Normal Control.
Gyu Chul CHUNG ; Dong Eun LEE ; Chang Ki YOON ; Hyun Woong KIM ; Jung Lim KIM
Journal of the Korean Ophthalmological Society 2017;58(2):165-170
PURPOSE: The purpose of this study was to compare inner retinal thickness and retinal nerve fiber layer (RNFL) thickness between fellow eyes with unilateral branch retinal vein occlusion (BRVO) and normal control eyes. METHODS: Retrospective cross-sectional study including 59 patients diagnosed with unilateral BRVO and 51 control subjects. Using spectral domain optical coherence tomography, we investigated the average, 4 quadrant, and 12 clock-hour RNFL thicknesses and the average, minimum, superior, superonasal, superotemporal, inferior, inferonasal, and inferotemporal thicknesses of the ganglion cell-inner plexiform layer (GCIPL) layer. RESULTS: Patients with unilateral BRVO had a higher incidence of hypertension. In the fellow eyes of the unilateral BRVO patients, 7 and 11 o'clock RNFL thicknesses were significantly thinner than for the control eyes. There was no significant difference in the GCIPL thickness between the two groups CONCLUSIONS: The RNFL thickness of the fellow eyes of the unilateral BRVO patients showed significant decreases in the 7 and 11 o'clock sectors (p=0.005, 0.017, respectively), whereas there was no significant difference in the GCIPL thickness between the two groups. In the RNFL thickness analysis, the 7 and 11 o'clock sectors were found to be dominant locations of decreased RNFL thickness for the open angle glaucoma. Further, glaucomatous change should be carefully monitored in the fellow eyes of unilateral BRVO patients.
Cross-Sectional Studies
;
Ganglion Cysts
;
Glaucoma
;
Glaucoma, Open-Angle
;
Humans
;
Hypertension
;
Incidence
;
Nerve Fibers
;
Retinal Vein Occlusion*
;
Retinal Vein*
;
Retinaldehyde*
;
Retrospective Studies
;
Tomography, Optical Coherence
7.Expression of E-cadherin/beta-catenin Complex in Uterine Cervix Cancer.
Sangjoon CHOI ; Seijun HAN ; Hyuk JUNG ; Tae Gyu AHN ; Chang Hoon SONG ; Sung Chul LIM
Korean Journal of Obstetrics and Gynecology 2003;46(7):1306-1315
OBJECTIVE: The objective of this study was to determine relationship between alteration of expression of E-cadherin, beta-catenin and tumor progression, clinical stage, lymph node metastasis, age of patients with uterine cervical cancer. METHODS: The authors evaluated the immunohistochemical expression pattern of E-cadherin and beta- catenin in relationship with tumor stage and clinicopathologic parameters in 71 cervical neoplasia including 36 cases of squamous cell carcinoma (SCC), 10 cases of microinvasive SCC, 22 cases of squamous cell carcinoma in situ, and 3 cases of severe dysplasia. RESULTS: There were aberrant expression in 76.1% of E-cadherin (54 of 71) and 74.6% of beta-catenin (53 of 71) in the cervical cancer. There was positive correlation of aberrant expression of E-cadherin with tumor progression and clinical stage (<0.005). There was positive correlation of aberrant expression of beta- catenin with tumor progression and clinical stage (<0.005). CONCLUSION: These results suggest that the degree or the pattern of E-cadherin, beta-catenin, and E-cadherin/beta-catenin complex may be related to histologic grade and clinical stage of uterine cervical cancer.
beta Catenin
;
Cadherins
;
Carcinoma, Squamous Cell
;
Cervix Uteri*
;
Female
;
Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Uterine Cervical Neoplasms
8.Chylous Ascites in a Patient Undergoing Continuous Ambulatory Peritoneal Dialysis.
Young Jun KIM ; Gyu Chul LIM ; Sun Ae LEE ; Chong Ik JUNG ; Jin Hwui KIM ; Duk Ho KWON ; Sang Yong JUNG ; Sang Yeol SUH
Korean Journal of Nephrology 1998;17(4):649-652
Chylous ascites is extravasation of lymphatic fluid and retention in the peritoneal cavity due to traurna or obstruction of the lymphatic system. Chylous ascites is very rare complication of Continuous Ambulatory Peritoneal Dialysis (CAPD) and is associated with trauma to the lymphatics during catheter insertion in the early stage of CAPD and repeated mild trauma to the lyrnphatics during longterm dialysis. Chylous ascites in the CAPD is suspected when the drained peritoneal fluid is milky white and confirmed by demonstration of the specific components of chyle, such as elevated triglyceride and low cholesterol than plasma and should be differentiated from pseudochyle and bacterial peritonitis. We report a case of chylous ascites in a patient undergoing CAPD at 2 months later of initiation of CAPD, which was not improved by conservative management. So CAPD catheter was removed and renal replacement therapy was changed to hemodialysis.
Ascitic Fluid
;
Catheters
;
Cholesterol
;
Chyle
;
Chylous Ascites*
;
Dialysis
;
Humans
;
Lymphatic System
;
Peritoneal Cavity
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis
;
Plasma
;
Renal Dialysis
;
Renal Replacement Therapy
;
Triglycerides
9.Autonomic Dysfunction in Chronic Renal Failure.
Sang Ho LEE ; Soo Chul CHOI ; Seoung Pyo HONG ; Tae Won LEE ; Chun Gyu LIM ; Myung Jae KIM
Korean Journal of Medicine 1998;55(2):221-231
OBJECTIVES : Impaired autonomic function in patients with chronic renal failure has been well documented in a number of studies to assess the degree of cardiovascular autonomic dysfunction and to assess the relationship with plasma catecholamines. The purpose of the present study was to evaluate the prevalence of autonomic dysfunction and to determine the effect of autonomic dysfunction on the increment of plasma catecholamine, dialysis-induced hypotension and hypotension during chronic dialysis. METHODS: We measured the degree of autonomic damage and the concentration of plasma catecholamines in 20 patients on maintenance hemodialysis, 12 pre- dialysis patients with chronic renal failure and 20 normal controls using a standardized battery of five cardiovascular reflex tests. RESULTS: 1) In normal controls, 70% of cases had a normal or early parasympathetic abnormalities however in patients with chronic renal failure, 45.2% of patients had severe abnormalities. The prevalence of autonomic dysfunction was 62.5% and there was significant correlation between sympathetic and parasympathetic score in patients with chronic renal failure. 2) Although overall autonomic function was not different in two chronic renal failure groups, the magnitude of heart rate response to Valsalva maneuver was increased and the magnitude of fall of blood pressure in response to standing-up was reduced in dialyzed patients compared with nondialyzed patients. 3) Patients with autonomic dysfunction was older and had higher postdialysis concentration of plasma norepinephrine than those with normal autonomic function. 4) In dialyzed patients, predialysis concentration of plasma norepinephrine at rest varied widely and was significantly related to the duration of dialysis. Postdialysis concentration of norepinephrine was significantly correlated with the degree of parasympathetic damage. 5) There were no significant differences in autonomic damage or plasma catecholamines whether dialysis- induced hypotension and hypotension in chronic hemodialysis or not. CONCLUSION : Disturbances of autonomic nerve system are common in chronic renal failure with distinct abnormalities of parasympathetic function and additional sympathetic dysfunction. Elevated plasma norepinephrine seems to be related to the compensatory response of sympathetic nerve system to parasympathetic damage. Impairment of autonomic function does not appear specifically related to dialysis-induced hypotension or hypotension in chronic dialysis.
Autonomic Pathways
;
Blood Pressure
;
Catecholamines
;
Dialysis
;
Heart Rate
;
Humans
;
Hypotension
;
Kidney Failure, Chronic*
;
Norepinephrine
;
Plasma
;
Prevalence
;
Reflex
;
Renal Dialysis
;
Valsalva Maneuver
10.Factor V Deficiency in Korean Patients: Clinical and Laboratory Features, Treatment, and Outcome.
Young Hoon PARK ; Joo Han LIM ; Hyeon Gyu YI ; Moon Hee LEE ; Chul Soo KIM
Journal of Korean Medical Science 2016;31(2):208-213
Due to rarity of factor V (FV) deficiency, there have been only a few case reports in Korea. We retrospectively analysed the clinical-laboratory features of FV deficiency in 10 Korean patients. Between January 1987 and December 2013, 10 case reports published in a Korean journal or proceedings of Korea Society on Thrombosis and Hemostasis were reviewed. Severity is defined as mild (> 5% of factor activity), moderate (1%-5%), and severe (< 1%). The median age at diagnosis, six males and four females, was 26 years (range, 1 month-73 years). Six of 10 patients were classified as moderate, three as mild, and one as severe disease. Eight patients were diagnosed as inherited FV deficiency. The most frequent symptoms were mucosal tract bleedings (40%) such as epistaxis, and menorrhagia in female. Hemarthroses and postoperative bleeding occurred in one and four patients, respectively. Life-threatening bleeding episodes occurred in the peritoneal cavity (n = 2), central nerve system (n = 1), and retroperitoneal space (n = 1). No lethal haemorrhages happened to patients with mild disease. The majority of bleeding episodes were controlled with local measures and fresh-frozen plasma replacement. Two acquired FV deficient-patients showing life-threatening haemorrhages received the immunosuppressive therapy, but one of them died from postoperative bleeding complications. Despite the small sample size of this study due to rarity of the disease, we found that Korean patients with FV deficiency had similar clinical manifestations and treatment outcomes shown in previous studies.
Adolescent
;
Adult
;
Aged
;
Asian Continental Ancestry Group
;
Blood Transfusion
;
Child
;
Databases, Factual
;
Factor V Deficiency/drug therapy/*pathology
;
Female
;
Hemorrhage/etiology
;
Humans
;
Immunoglobulins, Intravenous/therapeutic use
;
Immunosuppressive Agents/therapeutic use
;
Infant
;
Male
;
Middle Aged
;
Plasma
;
Republic of Korea
;
Retrospective Studies
;
Severity of Illness Index
;
Treatment Outcome
;
Young Adult