1.A Case of Congenital T Cell Lymphoblastic Lymphoma.
Eun Sun YOO ; Young Mi HONG ; Kyung Hee KIM ; Hae Soo GYU ; Eun Chul CHUNG
Journal of the Korean Pediatric Society 1994;37(9):1296-1304
T cell lymphoblastic lymphoma is characterized by immature lymphoid cells that are indistinguishable from the lymphoblasts and prolymphocytes of acute lymphoblastic leukemia. Several characteristic clinical features of lymphoblastic lymphoma, with include a high male-to-female ratio, a relatively high incidence in older children and young adults, the frequent presence of mediastinal involvement at the time of diagnosis. Also, this disease is rapidly progressive, and early dissemination to the bone marrow, blood, and central nervous system leads to the evolution of a picture resembling a acute lymphoblastic leukemia. We have experienced a rare case of congenital T-cell lymphoblastic lymphoma in which 1/365 year old female newborn had generalized multiple irregular protruding mass on her body. On bone marrow biopsy, CSF analysis, ultrasonogram and whole body MRI studies. We found metastasized tumor mass to, orbit, abdominal cavity, bulva, skin, and lower extremities. Histopathologically, specimen from mass on the right thigh showed diffuse infiltration of poorly differentiated and immature lymphoid cells in the skelectal muscle and subcutaneous soft tissue. By immunophenotyping studies using anti T cell and B cell monoclonal antibody, these cells were reactive with UCHL-1, MB2, but unreactive with MB1, L26. Based on these findings, the lesion was diagnosed as lymphoblastic lymphoma of the T-cell type, which occurred congenitally. Most T cell lymphoblastic lymphoma are noted, but congenital case was not reported. So we report it with a brief review of literature.
Abdominal Cavity
;
Biopsy
;
Bone Marrow
;
Central Nervous System
;
Child
;
Diagnosis
;
Female
;
Humans
;
Immunophenotyping
;
Incidence
;
Infant, Newborn
;
Lower Extremity
;
Lymphocytes
;
Magnetic Resonance Imaging
;
Orbit
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Skin
;
T-Lymphocytes
;
Thigh
;
Ultrasonography
;
Young Adult
2.Effects of chemical components of urine on sperm motility.
Korean Journal of Urology 1993;34(6):991-998
The acidity and osmolarity of urine, and semen contamination with cell suspension or bacteria in the urine could lower sperm motility of retrograde ejaculates. So far, however, very few reports about the influence of chemical components of the urine on the sperm motility have been published. In the present study, the effects or the major chemical components in the urine (ammonia, creatinine, urea, and uric acid) on the sperm motility were investigated. For objective and accurate determination of the sperm motility, Sperm Quality Analizer was utilized in addition to Makler counting chamber, and semens were taken from one and the same young man with normal spermiogram. The amount of the chemical components which were applied to the semen was determined by calculating their daily output in urine. Each test was repeated 5 times. The higher the concentration of The urine to normal saline in the state of the same pH and osmolarity, the lower the sperm motility, which means the chemical components of the urine may have detrimental effect on the motility. Uric acid, urea and crealinine had little effects on the motility, regardless of concentration until 30 minutes after exposure. But ammonit had acute lethal effect on the motility even in the minimal amount. In conclusion, ammonia seems to be one of the most import factors in urine detrimental to sperm motility.
Ammonia
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Bacteria
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Creatinine
;
Hydrogen-Ion Concentration
;
Osmolar Concentration
;
Semen
;
Sperm Motility*
;
Spermatozoa*
;
Urea
;
Uric Acid
3.Experimental Study on Alloplastic Spermatocele.
Korean Journal of Urology 1988;29(2):280-284
The "bridge" alloplastic spermatocele, which connected the tails of the both epididymis and collected sperms from both testes, were constructed in 30 male Wistar rats, using Goretex cylinder. The artificial cylinder were aspirated postoperatively every week for 8 weeks, and the animals were then sacrificed and the epididymis connected with spermatoceles were examined histologically. The valid experimental results were not obtained because of the inflammation. However, the surgical procedure was relatively easy and a greater quantity of aspirate was obtained with easy execution of the single puncture. The number of sperms was markedly decreased from the 3rd weeks, and no sperms were survived at the first week in all the experimental rats. Therefore, it is recommended that the basic aspect of the spermatocele should be worked out experimentally before applying it to human patients.
Animals
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Epididymis
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Humans
;
Inflammation
;
Male
;
Polytetrafluoroethylene
;
Punctures
;
Rats
;
Rats, Wistar
;
Spermatocele*
;
Spermatozoa
;
Testis
4.A Case of Antenatally Diagnosed Fetal Ovarian Cyst.
Chi Hun SONG ; Seo Yoo HONG ; Soo Mi CHUNG ; Kyung Chul HAN ; Chul Bum PARK ; Bong Gyu SHIN
Korean Journal of Obstetrics and Gynecology 1999;42(3):651-655
Ovarian cysts in the newborn are uncormnon. Fetal ovarian cysts are being diagnosed with inaeasing fiequency with development of obstetrical sonography. Most of these cysts are found within the first few months of life and have no clinical significance. But, a large ovarian cyst would be founded antenatally with sonography. A large ovarian cyst can cause life-theatening complications during parturition and in the neonatal period. We have experienced a case of fetal ovarian cyst in a 32-year-old primiparous woman with antenatal sonography and report our experience with a brief review of literatures.
Adult
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Female
;
Humans
;
Infant, Newborn
;
Ovarian Cysts*
;
Parturition
;
Ultrasonography
5.The significance of C-reactive protein levels in maternal serum with outcome of tocolysis.
Chung Ok PARK ; Tae Gyu PARK ; Chul Sung BAE ; Yoon Kee PARK ; Sung Ho LEE ; Wun Yong CHUNG
Korean Journal of Obstetrics and Gynecology 1991;34(6):781-789
No abstract available.
C-Reactive Protein*
;
Tocolysis*
6.Evaluation of repetitive sequence-based genomic fingerprinting for molecular classification and identification of vibrio species.
Gyu Won KIM ; Hun Jong CHUNG ; Chul Min PARK ; Kijeong KIM ; Wonyong KIM ; Sang In CHUNG
Korean Journal of Medicine 2006;71(2):189-197
BACKGROUND: The aims of this study were to compare the suitability of repetitive-PCR genomic fingerprinting procedures to investigate genetic relatedness of the genus Vibrio and its applicability for the molecular identification of Vibrio vulnificus. METHODS: Forty-eight Vibrio strains were included for this study. REP-, ERIC-, BOX- and SERE-PCR were compared with 13 members of the genus Vibrio. RESULTS: REP-, BOX- and SERE-PCR showed V. vulnificus strains could not be separated well from other Vibrio species. However, approximately 320 bp of highly discriminatory specific fragments was recovered from V. vulnificus strains by ERIC-PCR. CONCLUSIONS: ERIC-PCR could be used as rapid classification and identification methods of V. vulnificus from other members of the genus Vibrio.
Classification*
;
Dermatoglyphics*
;
Vibrio vulnificus
;
Vibrio*
7.The Differential Assessment of Human Cytomegalovirus Infectivity by in Situ Polymerase Chain Reaction.
Ki Chul SHIN ; Dae Joong KIM ; Jin Hee KIM ; Chung Gyu PARK ; Eung Soo HWANG ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1999;34(4):363-372
No abstract available.
Cytomegalovirus*
;
Humans*
;
Polymerase Chain Reaction*
8.Application of Goretex to Reconstruct Protrusion of the Prosthesis against Thin Tunicae Albuginea after Hydroflex Penile Prosthesis.
In Gyu CHOI ; Young Eun LEE ; Sae Chul KIM
Korean Journal of Urology 1989;30(2):286-289
We recently experienced a case of protrusion of the penile prosthesis against thin tunicae albuginea after Hydroflex penile prosthesis in a 30-year-old man having neurogenic and vasculogenic impotence associated with urethral injury. The thin tunicae albuginea were reconstructed by application of Goretex.
Adult
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Female
;
Humans
;
Impotence, Vasculogenic
;
Male
;
Penile Prosthesis*
;
Polytetrafluoroethylene*
;
Prostheses and Implants*
9.Efficacy of Primary Intravitreal Ranibizumab Injection for Treatment of Type 1 Retinopathy of Prematurity.
Gyu Chul CHUNG ; Sung Hyuk MOON
Journal of the Korean Ophthalmological Society 2017;58(9):1080-1086
PURPOSE: To evaluate the effectiveness and safety of primary intravitreal ranibizumab injection as a treatment for retinopathy of prematurity. METHODS: Retrospective analysis of the medical records of patients diagnosed with retinopathy of prematurity and treated with intravitreal ranibizumab injection from January 1, 2013 to January 1, 2016 was performed. We complied with the standards for ‘prethresold, type 1’ established by the Early Treatment of Retinopathy of Prematurity study for intravitreal ranibizumab injection. The follow-up period after injection was at least 9 months. Patients who received additional treatment such as laser photocoagulation or intravitreal injection without reactivation of retinopathy of prematurity were excluded. RESULTS: A total of 21 patients (39 eyes) were included in this study. Nine (16 eyes) were male and 12 (23 eyes) were female. The average duration between treatment decision and intravitreal ranibizumab injection was 2.1 ± 1.5 days. Complete regression of the plus sign occurred 18.2 ± 9.1days after injection. One eye with reactivation was treated with panretinal laser photocoagulation while four other eyes with reactivation were treated with intravitreal bevacizumab injection. There were 87.1% (34/39) eyes that underwent primary intravitreal ranibizumab injection with stable results without any reactivation. There were no systemic complications related to intravitreal ranibizumab injection. CONCLUSIONS: Primary intravitreal ranibizumab injection as a treatment for retinopathy of prematurity showed good efficacy and safety. However, thorough evaluation is needed after primary intravitreal ranibizumab injection due to the potential for reactivation. Long-term monitoring is needed after intravitreal ranibizumab injection.
Bevacizumab
;
Female
;
Follow-Up Studies
;
Humans
;
Intravitreal Injections
;
Light Coagulation
;
Male
;
Medical Records
;
Ranibizumab*
;
Retinopathy of Prematurity*
;
Retrospective Studies
10.Complications of Penile Prosthetic Surgery.
Sae Chul KIM ; In Gyu CHOI ; Chung Hwan OH
Korean Journal of Urology 1989;30(4):576-583
We have followed up 85 patients who have underwent penile prosthetic surgeries(Jonas ; 12. AMS 600 ; 33. AMS 700 ; 11, AMS 700 CX ; 5, Mentor ; 1, Hydroflex ; 23) for erectile dysfunction with a mean follow-up period of 28.7 months. Nineteen cases of complications in 15 patients(17.6%) developed of which 17 cases of medico-surgical in 14 patients and 2 cases of mechanical in one patient. As the medico-surgical complications, occurred a crural corporeal perforation, a protrusion of AMS 600 against glans, an acute angled protrusion of Hydroflex on penile base in flaccid state, 2 cases of exposure of Scott's inflatable prostheses through scrotal erosion (a case of tubing exposure and a case of pump exposure), two cases of urethral erosion and urine leak with infected prostheses, a skin necrosis of glans, 2 infected prostheses, 4 cases of urinary retention, and a dehiscence of perineal surgical wound. As the mechanical complications, crevice of the Hydroflex of both sides with fluid leak happened with 9 months interval in one patient.
Erectile Dysfunction
;
Follow-Up Studies
;
Humans
;
Male
;
Mentors
;
Necrosis
;
Penile Prosthesis
;
Prostheses and Implants
;
Skin
;
Urinary Retention
;
Wounds and Injuries