PURPOSE: We have examined the utility of 99mTc-MAG3 perfusion indices for assessing renal graft function in early post-transplantation period. MATERIALS AND METHODS: Our study included 80 renal transplant recipients (48 men and 32 women, mean age: 40.3 years). Diagnosis was based on biopsy, laboratory data and clinical course. Renal scintigraphy (RS) was obtained using 100 MBq of 99mTc-MAG3 from 11 days to 23 days of kidney transplantation. We measured 5 indices in whole-kidney (WK) and cortical (C) renograms; Hilson's perfusion index (PI), transplant perfusion index (TP) and transplant function index (TF) as perfusion parameter, and the time to peak activity (Tmax) and the ratio of renal counts at 20 min to that at 3 min (K20/3) as functional parameter. RESULTS: The diagnoses at the day of RS were normal graft (NG) in 44, acute rejection (AR) in 14, acute tubular necrosis (ATN) in 10, and Cyclosporine A nephrotoxicity (CsA) in 12. TP and TF were significantly decreased in AR, ATN and CsA, compared to those in NG. K20/3 of AR and ATN were significantly greater than that of NG. WK-Tmax of AR was significantly longer than that of NG. K20/3 of AR and C-K20/3 of ATN were significantly prolonged relative to those of CsA. There were no statistically significant perfusion indices among complication groups. CONCLUSION: TP and TF reflecting microperfusion and initial tubular extraction are reliable in assessing graft function. However, it is required to correlate perfusion indices with functional indices and clinical course in differentiating from one another among complication groups.
Biopsy ; Cyclosporine ; Diagnosis ; Female ; Humans ; Kidney Transplantation ; Male ; Necrosis ; Perfusion* ; Radionuclide Imaging ; Technetium Tc 99m Mertiatide* ; Transplantation ; Transplants

No abstract available.

No abstract available.
Anxiety Disorders* ; Anxiety* ; Humans ; Lymphocyte Subsets* ; Lymphocytes*

We studied the age of onset, occupation, inducing or aggravating factors, distribution of skin lesions in 153 patients and recall antigen test in 15 patients of seborrheic dermatitis. The results were as follows : l. Seborrhic dermatitis occurred most frequently at the third decade and the number of patients was 1(0.7%) in the first decade, 41(26.8%) in the second decade, 58(37.9 %) in the third decade, 29(l9.0%) in the fourth decade, 12(7.8%) in the fifth decade, 5(3.3%) in the sixth decade, 4(2.6%) in the seventh decade, and 3(1.9%) in the eighth decade 2. There was family history of seborrheic dermatitis in 40 patients(26.1%) 3. Of the occupations, 48 patients(31.4%) were clerks or office workers, 42 patients (27.5%) were housewives, 23 patients(15.0%) were laborers or factory workers, ll patients(7.2%) were students, 9 patients(5.9%) were managers, and 6 patients(3.9%) were drivers. 4. Inducing or aggravating factors were emotional stress in 75 patrents(49.0%), seasonal change in 53 patients(34.6%), sunlight in 23 patients(15.0%), foods in 15 patients(9.8%), upper respiratory tract infection in 14 patients(9.2%), menstruation in 9 patients(5.9%), and drinking of slcohol in 9 patients(5.9%). 5. I,esions occurred on the scalp in 128 patients(83.7%), on the face in 115 patients (75.2,l6), on the neck in 42 patients(27.5%), on the trunk in 29 patients(19.096), on the intertriginous areas in 12 patients(7.8%), and on the extremities in 6 patients(3.996), 6. The intensity and rate of delayed hypersensitivity reaction in 15 patients of seborrhic dermatitis(1.62+/-0.92mm, 28.67+26.4596) were not significantly decreased than those of control group(1.99+1.08mm, 39.23+/-22.34%) (p>0.05). Anergy and hypoergy were found in 10 patients(6796) with seborrheic dermatitis in contrast to 6 persons(4096) in control group.
Age of Onset ; Dermatitis ; Dermatitis, Seborrheic* ; Drinking ; Extremities ; Female ; Humans ; Hypersensitivity, Delayed ; Menstruation ; Neck ; Occupations ; Respiratory Tract Infections ; Scalp ; Seasons ; Skin ; Stress, Psychological ; Sunlight

PURPOSE: This study was aimed to determine the optimum low-density lipoprotein : high-density lipoprotein-cholesterol (LDL : HDL-C) ratio for predicting coronary heart disease(CHD) in Korean people. METHODS: It was analyzed this data of 5,431 adults who had undergone health examinations in a hospital in Gyeonggi-do between January 2006 and December 2007. The covariation of the coronary risk factors such as age, HbA1C, systolic blood pressure(SBP), and waist-to-stature ratio(WSR) were analyzed by using logistic regression analysis. RESULTS: The LDL : HDL-C ratio in the male and female groups was mostly distributed between 1.5 and 4.0. The LDL : HDL-C ratio was the most significant cholesterol-related parameter influencing CHD(male: B = .306, p = .054, female : B = .940, p = .010), followed by LDL-C and total cholesterol. It was observed a sharp increase in the odds ratios for LDL : HDL-C ratios of 2.25 - 2.50(male) and 2.00 - 2.25(female). A significant difference was observed in both male(2.25 : chi-square = 2.494, p = .072) and female(2.00 : chi-square = 413.742, p = .000) groups. CONCLUSION: The risk level of CHD was set to 2.25 for males and 2.00 for females. Therefore, the optimum LDL : HDL-C ratio for Koreans should be far lower than that for the people in western countries.
Adult ; Cholesterol ; Coronary Disease ; Female ; Heart ; Humans ; Lipoproteins ; Logistic Models ; Male ; Odds Ratio ; Risk Factors

No abstract available.
Colorectal Neoplasms* ; Neoplasm Metastasis*

Erythr odysesthesia syndrome is a. peculiar toxic reaction due to anti-cancer drug. lt is characterized by a painful, purple-colored patch on the palms and soles, and may form bullae. We report a case of erythrodysesthesia syndrome in a 46-year-old woman. 5-FU and leucovorin were administered for 5 days because of her colon cancer. Two weeks after anti-cancer therapy, purple-colored erosive patch appeared on the face, and 10 days later, purple-colored vesicular patches were seen on both palms and soles, accompanied with pain. Histopathologic examination reveals a severe epidermal necrosis. Individual keratinocyte shows cytologic atypia and apoptotic body.
Colonic Neoplasms ; Female ; Fluorouracil* ; Humans ; Keratinocytes ; Leucovorin ; Middle Aged ; Necrosis

PURPOSE: This study examined the relationship between sexual changes and adjustment and identified the factors which affect adjustment after a hysterectomy. METHOD: The subjects were 89 women under 50 years of age registered at gynecology departments of general hospitals in Seoul. RESULT: 60.7% of the women restarted coitus during six weeks to three months post operation. They felt a decrease in vaginal secretions (68%), and abdominal and pelvic pain (59.8%), but2/3 of them didn't change the frequency of coitus and level of orgasm. With respect to the adaptability of the sexual life, there was a significant difference in the time to restart coitus, lack of vaginal secretions, abdominal and pelvic pain, change of frequency of coitus, experience of orgasm, importance of sex and avoidance of coitus, according to job, income, and health condition. CONCLUSION: It is appropriate to restart coitus six weeks to three months after surgery and preliminary information should be given to patients after surgery as abdominal and pelvic pain could be relieved after twelve months. Also, sexual adjustment can be improved if they can recognize the changes after surgery from sexual life before surgery.
Middle Aged ; Hysterectomy/*psychology ; Humans ; Female ; Coitus ; Adult ; Adaptation, Psychological

PURPOSE: The purpose of this study was to classify the research domains and subjects based on existing health problems, sex/gender specific crucial health differences and common risks across the life span. METHOD: Three hundred and seventy seven articles were examined that were published in 3 nursing journals from 1999 to 2004. RESULTS: Research subjects were classified into middle-aged women (23%), nurses (20%), pregnant women (17%), school girls (14%), ill women (8%), working women (4%), elderly women (4%), mothers (3%), married women (3%), and unmarried women (2%) in sequence. The total number of keywords were 820 and the mean was 2.17 per article. Research domains were health behaviors (27%), childbirth (20%), socio-cultural and economic activities (8%), illness (6%), the reproductive system (5%), and demographics (5%) in the order of frequency. Research concepts shown were universal health behaviors (8.4%), mental health (7.2%), labor and delivery (6.2%), parent roles (5.5%), breast- feeding (4.6%), violence (4.5%), climacterics (4.3%), postpartum care (4.0%), weight control behaviors (3.8%), and a healthy life (3.5%) in frequency. CONCLUSION: Based on the research results, research concepts should be chosen closely related with the existing health problems, sex/gender specific differences and common risks across the life span. Especially these matters should be taken into consideration for study: education about the risks of artificial abortion, giving information for decision making on cesarean birth, low birth rates, infection during pregnancy, and the increasing rate of divorce.
Aged ; Birth Rate ; Climacteric ; Decision Making ; Demography ; Divorce ; Education ; Female ; Health Behavior ; Humans ; Mental Health ; Mothers ; Nursing ; Parents ; Parturition ; Postnatal Care ; Pregnancy ; Pregnant Women ; Research Subjects ; Single Person ; Violence ; Women's Health* ; Women, Working

PURPOSE: This study aimed to examine the relationship between pre and post operative sexual condition, differences in sexual attitude through post operational periods, and the relationship between sexual attitude and satisfaction. METHOD: Data was collected with questionares from 119 women registered in the gynecology department of a general hospital in Seoul who had undergone a hysterectomy. RESULT: There was a significant difference between the condition of pre and post operation coital frequency, sexual satisfaction, and spouse's attitude toward the extraction of the partner's uterus. There was a significant difference between their views of the operation. Twelve months after the operation sexual attitude of sexual aspects changed, but not in physical and psychological aspects. There was a significant difference between sexual attitude and satisfaction on sexual, psychological aspects, but not physical aspects. CONCLUSION: The findings suggest that a preliminary sexual condition be identified before surgery, scheduling the operation after helping a spouse gain a positive attitude about the hysterectomy, and couples in their 50's and older get counselling. Increased sexual satisfaction will develop with a belief in positive changes of sexual aspects, but a rapid change should not be expected.
Coitus ; Family Characteristics ; Female ; Gynecology ; Hospitals, General ; Humans ; Hysterectomy* ; Seoul ; Sexuality ; Spouses ; Uterus